听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览Current Osteoporosis Reports期刊下所有文献
  • Cell Sources for Human In vitro Bone Models.

    abstract:PURPOSE OF REVIEW:One aim in bone tissue engineering is to develop human cell-based, 3D in vitro bone models to study bone physiology and pathology. Due to the heterogeneity of cells among patients, patient's own cells are needed to be obtained, ideally, from one single cell source. This review attempts to identify the...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-020-00648-6

    authors: Ansari S,Ito K,Hofmann S

    更新日期:2021-01-15 00:00:00

  • Ex vivo Bone Models and Their Potential in Preclinical Evaluation.

    abstract:PURPOSE OF REVIEW:Novel therapies for damaged and diseased bone are being developed in a preclinical testing process consisting of in vitro cell experiments followed by in vivo animal studies. The in vitro results are often not representative of the results observed in vivo. This could be caused by the complexity of th...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-020-00649-5

    authors: Cramer EEA,Ito K,Hofmann S

    更新日期:2021-01-11 00:00:00

  • Romosozumab: a Review of Efficacy, Safety, and Cardiovascular Risk.

    abstract:PURPOSE OF REVIEW:Authors review the safety and efficacy of romosozumab for the treatment of osteoporosis as demonstrated in three phase III clinical trials and offer insights into the potential cardiovascular risk associated with its use. RECENT FINDINGS:Incidence of new vertebral fracture is dramatically reduced wit...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-020-00652-w

    authors: Fixen C,Tunoa J

    更新日期:2021-01-07 00:00:00

  • When the Nervous System Turns Skeletal Muscles into Bones: How to Solve the Conundrum of Neurogenic Heterotopic Ossification.

    abstract:PURPOSE OF REVIEW:Neurogenic heterotopic ossification (NHO) is the abnormal formation of extra-skeletal bones in periarticular muscles after damage to the central nervous system (CNS) such as spinal cord injury (SCI), traumatic brain injury (TBI), stroke, or cerebral anoxia. The purpose of this review is to summarize r...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-020-00636-w

    authors: Alexander KA,Tseng HW,Salga M,Genêt F,Levesque JP

    更新日期:2020-12-01 00:00:00

  • Correction to: Do Bisphosphonates Alleviate Pain in Children? A Systematic Review.

    abstract::In a previous version of this publication, the author Mercedes Rodriguez Celin's name was listed as M.R. Celin. ...

    journal_title:Current osteoporosis reports

    pub_type: 已发布勘误

    doi:10.1007/s11914-020-00637-9

    authors: Rodriguez Celin M,Simon JC,Krzak JJ,Fial AV,Kruger KM,Smith PA,Harris GF

    更新日期:2020-10-29 00:00:00

  • The Cannabinoids Effect on Bone Formation and Bone Healing.

    abstract:PURPOSE OF REVIEW:Here, we overview the latest findings from studies investigating the skeletal endocannabinoid (EC) system and its involvement in bone formation and resorption. RECENT FINDINGS:The endocannabinoid system consists of endogenous ligands, receptors, and enzymes. The main cannabinoids found in the cannabi...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-020-00607-1

    authors: Raphael-Mizrahi B,Gabet Y

    更新日期:2020-10-01 00:00:00

  • New and Old Osteocytic Cell Lines and 3D Models.

    abstract:PURPOSE OF REVIEW:The aim of this review was to compile a list of tools currently available to study bone cells and in particular osteocytes. As the interest (and importance) in osteocyte biology has greatly expanded over the past decade, new tools and techniques have become available to study these elusive cells, RECE...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-020-00613-3

    authors: Divieti Pajevic P

    更新日期:2020-10-01 00:00:00

  • Potential Importance of Immune System Response to Exercise on Aging Muscle and Bone.

    abstract:PURPOSE OF REVIEW:The age-related loss of skeletal muscle and bone tissue decreases functionality and increases the risk for falls and injuries. One contributing factor of muscle and bone loss over time is chronic low-grade inflammation. Exercise training is an effective countermeasure for decreasing the loss of muscle...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-020-00596-1

    authors: Cornish SM,Chilibeck PD,Candow DG

    更新日期:2020-08-01 00:00:00

  • New Developments in Fracture Risk Assessment for Current Osteoporosis Reports.

    abstract:PURPOSE OF REVIEW:Identifying individuals at high fracture risk can be used to target those likely to derive the greatest benefit from treatment. This narrative review examines recent developments in using specific risk factors used to assess fracture risk, with a focus on publications in the last 3 years. RECENT FIND...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-020-00590-7

    authors: Leslie WD,Morin SN

    更新日期:2020-06-01 00:00:00

  • The Skeletal Consequences of Bariatric Surgery.

    abstract:PURPOSE OF REVIEW:This review outlines the recent findings regarding the impact of bariatric surgery on bone. It explores potential mechanisms for skeletal changes following bariatric surgery and strategies for management. RECENT FINDINGS:Bone loss following bariatric surgery is multifactorial. Probable mechanisms inc...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-020-00579-2

    authors: Krez AN,Stein EM

    更新日期:2020-06-01 00:00:00

  • Osteocyte-Mediated Translation of Mechanical Stimuli to Cellular Signaling and Its Role in Bone and Non-bone-Related Clinical Complications.

    abstract:PURPOSE OF REVIEW:Osteocytes comprise > 95% of the cellular component in bone tissue and produce a wide range of cytokines and cellular signaling molecules in response to mechanical stimuli. In this review, we aimed to summarize the molecular mechanisms involved in the osteocyte-mediated translation of mechanical stimu...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-020-00564-9

    authors: Yan Y,Wang L,Ge L,Pathak JL

    更新日期:2020-02-01 00:00:00

  • The Interrelationship Between Diabetes, IL-17 and Bone Loss.

    abstract:PURPOSE OF REVIEW:Diabetes has a detrimental effect on bone, increasing the risk of fracture and formation of osteolytic lesions such as those seen in periodontitis. Several diabetic complications are caused by diabetes-enhanced inflammation. This review examines mechanisms by which IL-17 contributes to diabetes-enhanc...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-020-00559-6

    authors: Huang Z,Pei X,Graves DT

    更新日期:2020-02-01 00:00:00

  • Biomechanics of Osteoporotic Fracture Fixation.

    abstract:PURPOSE OF REVIEW:Fractures of osteoporotic bone in elderly individuals need special attention. This manuscript reviews the current strategies to provide sufficient fracture fixation stability with a particular focus on fractures that frequently occur in elderly individuals with osteoporosis and require full load-beari...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-019-00535-9

    authors: Hollensteiner M,Sandriesser S,Bliven E,von Rüden C,Augat P

    更新日期:2019-12-01 00:00:00

  • Monocyte Chemoattractant Protein-1 (MCP-1/CCL2) Drives Activation of Bone Remodelling and Skeletal Metastasis.

    abstract:PURPOSE OF REVIEW:The purpose of this review is to explore the role of monocyte chemoattractant protein-1 (MCP-1 or CCL2) in the processes that underpin bone remodelling, particularly the action of osteoblasts and osteoclasts, and its role in the development and metastasis of cancers that target the bone. RECENT FINDI...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-019-00545-7

    authors: Mulholland BS,Forwood MR,Morrison NA

    更新日期:2019-12-01 00:00:00

  • Quality Measures and Quality Improvement Initiatives in Osteoporosis-an Update.

    abstract:PURPOSE OF REVIEW:The aims of this review are to summarize current performance for osteoporosis quality measures used by Centers for Medicare and Medicaid (CMS) for pay-for-performance programs and to describe recent quality improvement strategies around these measures. RECENT FINDINGS:Healthcare Effectiveness Data an...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-019-00547-5

    authors: French S,Choden S,Schmajuk G

    更新日期:2019-12-01 00:00:00

  • Cellular Processes by Which Osteoblasts and Osteocytes Control Bone Mineral Deposition and Maturation Revealed by Stage-Specific EphrinB2 Knockdown.

    abstract:PURPOSE OF REVIEW:We outline the diverse processes contributing to bone mineralization and bone matrix maturation by describing two mouse models with bone strength defects caused by restricted deletion of the receptor tyrosine kinase ligand EphrinB2. RECENT FINDINGS:Stage-specific EphrinB2 deletion differs in its effe...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-019-00524-y

    authors: Blank M,Sims NA

    更新日期:2019-10-01 00:00:00

  • RNA-seq in Skeletal Biology.

    abstract:PURPOSE OF REVIEW:The goal of this paper is to review state-of-the-art transcriptome profiling methods and their recent applications in the field of skeletal biology. RECENT FINDINGS:Next-generation sequencing of mRNA (RNA-seq) methods have been established and routinely used in skeletal biology research. RNA-seq has ...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-019-00517-x

    authors: Ayturk U

    更新日期:2019-08-01 00:00:00

  • A Second Career for Chondrocytes-Transformation into Osteoblasts.

    abstract:PURPOSE OF REVIEW:The goal of the review is to summarize the current knowledge on the process of chondrocyte-to-osteoblast transdifferentiation during endochondral bone formation and its potential implications in fracture healing and disease. RECENT FINDINGS:Lineage tracing experiments confirmed the transdifferentiati...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-019-00511-3

    authors: Wolff LI,Hartmann C

    更新日期:2019-06-01 00:00:00

  • Glucocorticoid-Induced Osteoporosis: New Insights into the Pathophysiology and Treatments.

    abstract:PURPOSE OF THIS REVIEW:The goal of the review is to provide an updated understanding of the pathophysiology of glucocorticoid-induced osteoporosis and treatment recommendations. RECENT FINDINGS:Glucocorticoids reduce osteoblast and osteocyte lifespan and activity and reduce the vascularity of the bone that together ma...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-019-00498-x

    authors: Lane NE

    更新日期:2019-02-01 00:00:00

  • In Vivo Osteocyte Mechanotransduction: Recent Developments and Future Directions.

    abstract:PURPOSE OF REVIEW:Mechanical loading is an essential stimulus for skeletal tissues. Osteocytes are primarily responsible for sensing mechanical stimuli in bone and for orchestrating subsequent responses. This is critical for maintaining homeostasis, and responding to injury/disease. The osteocyte mechanotransduction pa...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-018-0485-1

    authors: Hinton PV,Rackard SM,Kennedy OD

    更新日期:2018-12-01 00:00:00

  • Carbon Nanomaterials for Treating Osteoporotic Vertebral Fractures.

    abstract:PURPOSE OF REVIEW:To identify the use of carbon nanomaterials in bone regeneration and present new data on the regenerative capacity of bone tissue in osteopenic rats treated with graphene nanoribbons (GNRs). RECENT FINDINGS:The results show that the physical and chemical properties of the nanomaterials are suitable f...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-018-0476-2

    authors: de Carvalho JO,de Carvalho Oliveira F,Freitas SAP,Soares LM,de Cássia Barros Lima R,de Sousa Gonçalves L,Webster TJ,Marciano FR,Lobo AO

    更新日期:2018-10-01 00:00:00

  • Fracture Prediction by Computed Tomography and Finite Element Analysis: Current and Future Perspectives.

    abstract:PURPOSE OF REVIEW:This review critiques the ability of CT-based methods to predict incident hip and vertebral fractures. RECENT FINDINGS:CT-based techniques with concurrent calibration all show strong associations with incident hip and vertebral fracture, predicting hip and vertebral fractures as well as, and sometime...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-018-0450-z

    authors: Johannesdottir F,Allaire B,Bouxsein ML

    更新日期:2018-08-01 00:00:00

  • Current Understanding of Epidemiology, Pathophysiology, and Management of Atypical Femur Fractures.

    abstract:PURPOSE OF REVIEW:To summarize reports published since the 2013 American Society of Bone and Mineral Research Task Force Report on atypical femoral fractures (AFF). RECENT FINDINGS:The absolute incidence of AFFs remains low. AFFs are primarily associated with prolonged bisphosphonate (BP) exposure, but have also been ...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-018-0464-6

    authors: Starr J,Tay YKD,Shane E

    更新日期:2018-08-01 00:00:00

  • New Insights in Understanding and Treating Bone Fracture Pain.

    abstract:PURPOSE OF REVIEW:This paper describes recent advances in understanding the mechanisms that drive fracture pain and how these findings are helping develop new therapies to treat fracture pain. RECENT FINDINGS:Immediately following fracture, mechanosensitive nerve fibers that innervate bone are mechanically distorted. ...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-018-0446-8

    authors: Mitchell SAT,Majuta LA,Mantyh PW

    更新日期:2018-08-01 00:00:00

  • Vitamin D Activity and Metabolism in Bone.

    abstract:PURPOSE OF REVIEW:In addition to the actions of the endocrine hormone, 1alpha,25-dihydroxyvitamin D (1,25(OH)2D) in stimulating intestinal calcium absorption, the regulation of bone mineral metabolism by 1,25(OH)2D is also considered an important contributor to calcium homeostasis. However, recent evidence suggest that...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-017-0394-8

    authors: Anderson PH

    更新日期:2017-10-01 00:00:00

  • microRNA Regulation of Skeletal Development.

    abstract:PURPOSE OF REVIEW:Osteogenesis is a complex process involving the specification of multiple progenitor cells and their maturation and differentiation into matrix-secreting osteoblasts. Osteogenesis occurs not only during embryogenesis but also during growth, after an injury, and in normal homeostatic maintenance. While...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-017-0379-7

    authors: Sera SR,Zur Nieden NI

    更新日期:2017-08-01 00:00:00

  • Denosumab: an Emerging Therapy in Pediatric Bone Disorders.

    abstract:PURPOSE OF REVIEW:Denosumab is an inhibitor of receptor activator of nuclear factor kappa-B ligand (RANKL), and has emerged as an important novel therapy for skeletal disorders. This article examines the use of denosumab in children. RECENT FINDINGS:Considerable safety and efficacy data exists for denosumab treatment ...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-017-0380-1

    authors: Boyce AM

    更新日期:2017-08-01 00:00:00

  • Inherited Arterial Calcification Syndromes: Etiologies and Treatment Concepts.

    abstract:PURPOSE OF REVIEW:We give an update on the etiology and potential treatment options of rare inherited monogenic disorders associated with arterial calcification and calcific cardiac valve disease. RECENT FINDINGS:Genetic studies of rare inherited syndromes have identified key regulators of ectopic calcification. Based...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-017-0370-3

    authors: Nitschke Y,Rutsch F

    更新日期:2017-08-01 00:00:00

  • Diabetes and Bone Marrow Adiposity.

    abstract:PURPOSE OF REVIEW:This study aims to describe bone marrow fat changes in diabetes and to discuss the potential role of marrow fat in skeletal fragility. RECENT FINDINGS:Advances in non-invasive imaging have facilitated marrow fat research in humans. In contrast to animal studies which clearly demonstrate higher levels...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-016-0336-x

    authors: Kim TY,Schafer AL

    更新日期:2016-12-01 00:00:00

  • MicroRNA Exert Macro Effects on Cancer Bone Metastasis.

    abstract::Bone metastasis is a deadly complication of cancers arising from many different primary tumor locations. Cross talk between cancer and bone cells is a well-established driver of bone metastasis, and recent work reveals microRNA (miRNA) as key players in this communication. Functional significance of miRNA was first de...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-016-0316-1

    authors: Baier SR,Wan Y

    更新日期:2016-10-01 00:00:00

  • Risk Factors, Epidemiology and Treatment Strategies for Metabolic Bone Disease in Patients with Neurological Disease.

    abstract::Metabolic bone disease is a major public health concern, especially when it manifests as hip fracture which carries significant morbidity and mortality. Individuals with neurological disease are at higher risk of osteopenia, osteoporosis and fragility fracture compared to age-matched controls, yet this is under-apprec...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-016-0320-5

    authors: Binks S,Dobson R

    更新日期:2016-10-01 00:00:00

  • Mouse Models of Frailty: an Emerging Field.

    abstract::Frailty is highly prevalent in the elderly, increasing the risk of poor outcomes that include falls, incident disability, hospitalization, and mortality. Thus, a great need exists to characterize the underlying mechanisms and ultimately identify strategies that prevent, delay, and even reverse frailty. Mouse models ca...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-015-0283-y

    authors: Seldeen KL,Pang M,Troen BR

    更新日期:2015-10-01 00:00:00

  • Altered Central Sensitization and Pain Modulation in the CNS in Chronic Joint Pain.

    abstract::Musculoskeletal pain disorders are the second largest contributor to global disability underlining the significance of effective treatments. However, treating chronic musculoskeletal pain, and chronic joint pain (osteoarthritis (OA)) in particular, is challenging as the underlying peripheral and central pain mechanism...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-015-0276-x

    authors: Arendt-Nielsen L,Skou ST,Nielsen TA,Petersen KK

    更新日期:2015-08-01 00:00:00

  • Bone cells and bone turnover in diabetes mellitus.

    abstract::Substantial evidence exists that in addition to the well-known complications of diabetes, increased fracture risk is an important morbidity. This risk is probably due, at least in part, to altered bone remodeling and bone cell function in diabetes. Circulating biochemical markers of bone formation, including P1NP, ost...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章

    doi:10.1007/s11914-015-0265-0

    authors: Rubin MR

    更新日期:2015-06-01 00:00:00

  • Defective skeletal mineralization in pediatric CKD.

    abstract::Although traditional diagnosis and treatment of renal osteodystrophy focused on changes in bone turnover, current data demonstrate that abnormalities in skeletal mineralization are also prevalent in pediatric chronic kidney disease (CKD) and likely contribute to skeletal morbidities that continue to plague this popula...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-015-0253-4

    authors: Wesseling-Perry K

    更新日期:2015-04-01 00:00:00

  • Orthobiologics in the augmentation of osteoporotic fractures.

    abstract::Many orthobiologic adjuvants are available and widely utilized for general skeletal restoration. Their use for the specific task of osteoporotic fracture augmentation is less well recognized. Common conductive materials are reviewed for their value in this patient population including the large group of allograft adju...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-014-0249-5

    authors: Watson JT,Nicolaou DA

    更新日期:2015-02-01 00:00:00

  • Calcium supplementation: is protecting against osteoporosis counter to protecting against cardiovascular disease?

    abstract::Calcium is the dominant mineral in bone and is a shortfall nutrient in the diet. For those consuming inadequate dietary calcium, calcium supplements have been a standard strategy for prevention of osteoporosis. Recently, calcium supplementation has been linked to both increased and decreased cardiovascular disease ris...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-014-0208-1

    authors: Weaver CM

    更新日期:2014-06-01 00:00:00

  • Statistical shape and appearance models in osteoporosis.

    abstract::Statistical models (SMs) of shape (SSM) and appearance (SAM) have been acquiring popularity in medical image analysis since they were introduced in the early 1990s. They have been primarily used for segmentation, but they are also a powerful tool for 3D reconstruction and classification. All these tasks may be require...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-014-0206-3

    authors: Castro-Mateos I,Pozo JM,Cootes TF,Wilkinson JM,Eastell R,Frangi AF

    更新日期:2014-06-01 00:00:00

  • Endocrine crosstalk between muscle and bone.

    abstract::The musculoskeletal system is a complex organ comprised of the skeletal bones, skeletal muscles, tendons, ligaments, cartilage, joints, and other connective tissue that physically and mechanically interact to provide animals and humans with the essential ability of locomotion. This mechanical interaction is undoubtedl...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-014-0209-0

    authors: Brotto M,Johnson ML

    更新日期:2014-06-01 00:00:00

  • Therapies for musculoskeletal disease: can we treat two birds with one stone?

    abstract::Musculoskeletal diseases are highly prevalent with staggering annual health care costs across the globe. The combined wasting of muscle (sarcopenia) and bone (osteoporosis)-both in normal aging and pathologic states-can lead to vastly compounded risk for fracture in patients. Until now, our therapeutic approach to the...

    journal_title:Current osteoporosis reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11914-014-0204-5

    authors: Girgis CM,Mokbel N,Digirolamo DJ

    更新日期:2014-06-01 00:00:00

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