解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND:Up to 50% of patients suffer short-term postoperative adverse events (AEs) and metastatic recurrence in the long-term following curative-intent lung cancer resection. The association between AEs, particularly infectious in nature, and disease recurrence is controversial. We sought to evaluate the association...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00395-6
更新日期:2020-12-01 00:00:00
abstract:INTRODUCTION:Lung cancer is the leading cause of cancer death in the USA, claiming more than 140,000 deaths annually. Delays in diagnosis and treatment can lead to missed opportunities for both curative and life prolonging therapies. This study aimed to evaluate duration of time to diagnosis and first treatment, as wel...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00404-8
更新日期:2020-12-01 00:00:00
abstract::Cardiothoracic surgery posits an arrangement of large, significant hemodynamic, and physiologic alterations upon the human body, which predisposes a patient to develop pathology. The care of these patients in the postoperative realm requires an astute physician with deep understanding of the cardiopulmonary system, wh...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-020-00405-7
更新日期:2020-12-01 00:00:00
abstract::Benralizumab and mepolizumab are new therapies for severe eosinophilic asthma. They are both humanized IgG antibodies, targeting the IL-5 receptor and IL-5, respectively, suppressing the corresponding pathways. No specific biomarkers have been proposed to evaluate treatment response to benralizumab or mepolizumab. The...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00379-6
更新日期:2020-10-01 00:00:00
abstract:INTRODUCTION:Driving pressure (DP) while on ECMO has been studied in acute respiratory distress syndrome (ARDS) but no studies exist in those on ECMO without ARDS. We aimed to study association of mortality with DP in all patients on ECMO and compare change in DP before and after initiation of ECMO. METHODS:Consecutiv...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00381-y
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:The immuno-nutritional status is closely related to the prognosis in many cancers. Controlling nutritional status (CONUT) score is a new parameter that reflects the immuno-nutritional status and is prognostic in some cancers. However, the prognostic significance of the CONUT score in small cell lung cancer (SCL...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00361-2
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:This study was conducted to investigate the percentages of Th22 and Th17 cells in the peripheral blood of septic patients with and without acute lung injury (ALI) and their clinical significance. METHODS:A total of 479 patients were divided into non-ALI and ALI groups. The percentages of Th22 and Th17 cells an...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00362-1
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:Pulmonary arteriovenous malformations (PAVMs) are most commonly associated with hereditary hemorrhagic telangiectasia (HHT). Patients with PAVMs can present with serious complications including stroke, transient ischemic attack (TIA), and brain abscess. PAVMs are rare in non-HHT patients and little is known abo...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00367-w
更新日期:2020-08-01 00:00:00
abstract:INTRODUCTION:To evaluate the cardio-pulmonary hemodynamics changes before and after valve treatment, and their correlation with lobe volume reduction. METHODS:This retrospective multicentre study included consecutive patients undergoing bronchoscopic valve treatment for heterogeneous emphysema. In addition to standard...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00351-4
更新日期:2020-06-01 00:00:00
abstract:OBJECTIVE:To explore the role of CARM1 in lung cancer (LC) and its relationship with TP53 and CTNNB1. METHODS:Lung cells H1299 and PC14 were randomly divided into six groups: ov-H1299, si-H1299, ov-PC14, si-PC14, Con-H1299, and Con-PC14. Transwell assay, plate clone formation assay, and flow cytometry were used to det...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00324-7
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:Nicorandil is a hybrid between nitrates and KATP channel opener activators. The aim of this study was to evaluate the nicorandil's effects on ischemia-reperfusion (IR) lung injury and examine the mechanism of its effects. METHODS:Isolated rat lungs were divided into 6 groups. In the sham group, the lungs were ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00339-0
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:In obstructive sleep apnea (OSA), hypoxia secondary to apnea and hypopnea and the resulting systemic inflammatory response are the main causes of comorbidities. The aim of this study was to investigate the relationship between OSA and vimentin, which plays an important role in the activation of cells that synth...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-020-00341-6
更新日期:2020-04-01 00:00:00
abstract::Impaired phagocytosis of Pseudomonas aeruginosa was found in isolated monocytes of peripheral blood of cystic fibrosis patients, but not in their neutrophils, as reported some years ago. In the present study, we analysed the phagocytic capacity of peripheral blood neutrophils and monocytes of cystic fibrosis patients ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00290-9
更新日期:2020-02-01 00:00:00
abstract::The contribution of T-cells after lung transplant (LTx) remains controversial with no current consensus of their role concerning chronic lung allograft dysfunction. Using flow cytometry to assess T-cell subsets of bronchoalveolar lavage fluid (BALF) in 16 cystic fibrosis (CF) LTx recipients, we identified a decline in...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00298-1
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Several new treatments for severe asthma have become available in the last decade; yet, little data exist to guide their use in specific patient populations. OBJECTIVE:A network meta-analysis was conducted comparing the efficacy of FDA-approved monoclonal antibody therapies in preventing exacerbations in pa...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00310-8
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Prolonged exposure to crystalline silica leads to persistent pulmonary inflammation and progressive fibrosis. Connective tissue growth factor (CTGF) has emerged as a potent proinflammatory and profibrotic regulator to participate in a variety of chronic inflammatory diseases. However, the role of CTGF in sil...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00272-x
更新日期:2019-12-01 00:00:00
abstract::Lung cancer screening (LCS) is currently advocated in a subset of current or former smokers with a thirty pack-year smoking history or higher. Studies report that few patients meeting the criteria for screening are undergoing LCS. We conducted a survey to assess if barriers to LCS (race, ethnicity, and socioeconomic s...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00281-w
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Microbiological cultures are the mainstay of the diagnosis of tuberculosis (TB). False-positive TB results lead to significant unnecessary therapeutic and economic burden and are frequently caused by laboratory cross-contamination. The aim of this meta-analysis was to quantify the prevalence of laboratory cr...
journal_title:Lung
pub_type: 杂志文章,meta分析
doi:10.1007/s00408-019-00241-4
更新日期:2019-10-01 00:00:00
abstract:INTRODUCTION:The cardinal symptom of pulmonary hypertension (PH) is dyspnea on exertion, leading to decreased activity in daily living. The aim of this study was to analyze daily physical activity in incident patients with arterial or chronic thromboembolic PH (PAH/CTEPH) and to investigate its correlation with pulmona...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00248-x
更新日期:2019-10-01 00:00:00
abstract::The original version of this article contained an error in the usage of the term "false positive rate". The intention of the authors in those instances was simply to compare the absolute percentage of false positive results in the study vs the NLST, not to make any observations about false positive rate in the strict ...
journal_title:Lung
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00408-019-00269-6
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Sarcoidosis is a systemic disease in which the personal environment seems to drive a differentiated disease frequency and clinical expression. The main epidemiological studies suggest a key influence of potential environmentally linked exposures related to the type of occupation, the household, life style, s...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-019-00243-2
更新日期:2019-08-01 00:00:00
abstract::We aimed to evaluate the utility of coagulation markers for the prediction of rapidly progressive interstitial lung disease (RP-ILD) in patients with dermatomyositis (DM). In this retrospective study, 29 patients with DM-associated ILD were analyzed. The number of patients with RP-ILD was 15 (52%). The baseline clinic...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00245-0
更新日期:2019-08-01 00:00:00
abstract::This multi-centred, randomised controlled trial explored the effects of adding ongoing feedback to a 12-month unsupervised maintenance walking program, on daily physical activity (PA) in people with chronic obstructive pulmonary disease. Participants were randomised to either an intervention group (IG) or a usual care...
journal_title:Lung
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00408-019-00216-5
更新日期:2019-06-01 00:00:00
abstract::A large-scale outbreak of life-threatening, inhaled synthetic cannabinoids (Spice/K2)-associated coagulopathy with bleeding complications was recently reported in Illinois. The causative agents were brodifacoum, difenacoum, and bromadiolone, potent, long-acting, 4-hydroxycoumarin anticoagulant rodenticides (LAAR) that...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00227-2
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:To investigate whether lung function, especially when complicated with SDB, has an increased risk for myocardial infarction (MI) and congestive heart failure (CHF). METHODS:A prospective study was performed within the Sleep Heart Health Study (SHHS). A total of 4161 individuals were followed up for an average ...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00229-0
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:TB nanodiagnostics have witnessed considerable development. However, most of the published reports did not proceed beyond proof-of-concept. Our objectives are to evaluate the diagnostic accuracy of a novel nanogold assay in detecting patients with active pulmonary TB based on results of BACTEC MGIT (reference t...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-018-00194-0
更新日期:2019-04-01 00:00:00
abstract::Recent research showed group B patients express higher mortality compared to group C patients when GOLD A-D grouping is used. We aimed to compare the prognostic accuracy of three GOLD classification systems, I-IV ("pre-2011"), A-D ("2011-2016") and A-D ("2017-present") in relation to mortality, exacerbation risk, qual...
journal_title:Lung
pub_type: 杂志文章,多中心研究
doi:10.1007/s00408-019-00196-6
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:To investigate inpatient prevalence, expenditures, and comorbidities of hospitalized patients with sarcoidosis in the USA. METHODS:Patients with sarcoidosis were identified within the Nationwide Inpatient Sample (NIS) database for the years 2013 and 2014 using the respective ICD-9 diagnostic code. Data on pati...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-019-00210-x
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Transbronchial lung biopsy (TBBX) is a common respiratory diagnostic procedure performed to investigate several lung diseases. There are different types of forceps used to perform this procedure. The alligator and cupped (oval) forceps are most commonly used ones. To date, there are few studies that have com...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-018-0179-6
更新日期:2019-02-01 00:00:00
abstract:: ...
journal_title:Lung
pub_type: 信件
doi:10.1007/s00408-018-0187-6
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:Long Acting Beta2 Agonists (LABA) prevent COPD exacerbations in strictly standardized clinical trials. Our aim was to evaluate the relationship between the amount of LABA provided by the government and the trend in COPD hospital admission (HA) rate in Brazil. METHODS:This is a longitudinal large-scale real-lif...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-018-0158-y
更新日期:2018-12-01 00:00:00
abstract::It is well known that chronic obstructive pulmonary disease (COPD) patients present with muscle dysfunction that may not correlate with the degree of severity of airflow obstruction. Historically, the strength deficit of the knee extensor musculature (quadriceps) has been described as an independent factor of mortalit...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-018-0164-0
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare pulmonary condition, characterized by diffuse proliferation of neuroendocrine cells in the respiratory epithelium. DIPNECH lesions are less than 5 mm in size and are limited to the basement membrane with no invasion. There is li...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-018-0149-z
更新日期:2018-10-01 00:00:00
abstract::Bronchiectasis is characterized by deregulated inflammatory response and recurrent bacterial infection resulting in progressive lung damage and an irreversible dilatation of bronchi and bronchioles. Generally accepted model of the development of bronchiectasis is the "vicious cycle hypothesis" that proposes compromisi...
journal_title:Lung
pub_type: 杂志文章,评审
doi:10.1007/s00408-018-0121-y
更新日期:2018-08-01 00:00:00
abstract:INTRODUCTION:Flexible fiberoptic bronchoscopy (FFB) plays an important role in the surveillance of cystic fibrosis (CF) patients after lung transplantation (LTx). With rapid onset and clearance, propofol provides a safe and efficient method for sedation during FFB, yet sedation requirements for CF patients are not well...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-018-0119-5
更新日期:2018-08-01 00:00:00
abstract::The original version of this article unfortunately contained a mistake in the article title. The correct article title is "Residual Renal Function and Obstructive Sleep Apnea in Peritoneal Dialysis: A Pilot Study". ...
journal_title:Lung
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00408-018-0135-5
更新日期:2018-08-01 00:00:00
abstract::Adolescent idiopathic scoliosis may require surgical treatment for extreme curvature of the spine or loss of pulmonary function. We present a report of a 31-year-old woman with a history of scoliosis and anterolateral spinal fusion who developed chest pain and hemoptysis. Imaging revealed that a fixation rod had migra...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-018-0104-z
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:The right ventricular ejection fraction (RVEF) is a surrogate marker of right ventricular function in pulmonary hypertension (PH), but its measurement is complicated and time consuming. The tricuspid annular plane systolic excursion (TAPSE) measures only the longitudinal component of RV contraction while the...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-018-0089-7
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Histological subdivision into typical (TC) and atypical (AC) is crucial for treatment and prognosis of lung carcinoids but can be also very challenging, even for experts. In this study, we aimed to strengthen or reduce the prognostic value of several pathological, clinical, or per-operative factors some of w...
journal_title:Lung
pub_type: 杂志文章,多中心研究
doi:10.1007/s00408-017-0056-8
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:Sarcoidosis is a chronic granulomatous inflammatory disease of unknown etiology with heterogeneous outcomes. This study reviewed the clinical outcome status (COS) and organ involvement of Israeli sarcoidosis patients during a five-year period. Further, we compared our results to the 'World Association of Sarcoi...
journal_title:Lung
pub_type: 杂志文章
doi:10.1007/s00408-017-0015-4
更新日期:2017-08-01 00:00:00