听力与言语-语言病理学

行为科学

医学伦理学

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  • Obstetric Outcomes in Military Servicewomen: Emerging Knowledge, Considerations, and Gaps.

    abstract::The number of women in the U.S. military is dramatically increasing. Similarly, the roles of active-duty women are greatly expanding, thus exposing them to new occupational risks. Determining the impact of pregnancy outcomes for women while in the military is difficult due to changing exposures over time, difficulty i...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章

    doi:10.1055/s-0040-1712929

    authors: Mezwa K,Adelsheim L,Markenson G

    更新日期:2019-09-01 00:00:00

  • Neuropeptide Control of Puberty: Beyond Kisspeptins.

    abstract::Puberty is a fundamental developmental event in the lifespan of any individual, when sexual and somatic maturation is completed, and reproductive capacity is achieved. While the tempo of puberty is under strong genetic determination, it is also modulated by a wide array of internal and environmental cues, including, p...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0039-3400967

    authors: Barroso A,Roa J,Tena-Sempere M

    更新日期:2019-07-01 00:00:00

  • Neurokinin B and Neurokinin-3 Receptor Signaling: Promising Developments in the Management of Menopausal Hot Flushes.

    abstract::Vasomotor symptoms, including hot flushes and night sweats, pose a significant symptomatic burden to women undergoing menopause, and negatively impact on both their physical and psychological well-being. Management of these symptoms can be challenging, with the use of conventional hormone replacement therapy limited b...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0039-3400241

    authors: Modi M,Dhillo WS

    更新日期:2019-05-01 00:00:00

  • Infertility and the Military Male.

    abstract::Male infertility is a condition that affects approximately 50% of infertile couples and about 30% of those couples have only male factor infertility identified. There has been speculation that male military service members may have an even greater lifetime prevalence of infertility as compared to the general populatio...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0039-1694027

    authors: Reed-Maldonado AB,Madden KC

    更新日期:2019-01-01 00:00:00

  • The Department of Defense Birth and Infant Health Research Program: Assessing the Reproductive Health of U.S. Active-Duty Women.

    abstract::As the percentage of women serving in the active-duty military continues to grow, and as their roles continue to expand, the importance of monitoring reproductive health in the military community increases. The Department of Defense Birth and Infant Health Research (BIHR) program conducts ongoing epidemiologic studies...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0039-1678751

    authors: Khodr ZG,Bukowinski AT,Hall C,Gumbs GR,Wells NY,Conlin AMS

    更新日期:2018-11-01 00:00:00

  • Sperm Epigenetics and Its Impact on Male Fertility, Pregnancy Loss, and Somatic Health of Future Offsprings.

    abstract::Sperm epigenetic programming is tailored to meet the need of this specialized cell, which include its interaction with the oocyte during fertilization and early embryo development. The unique nature of the sperm epigenome has resulted in multiple studies investigating how perturbations in epigenetics might impact male...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0038-1677047

    authors: Ibrahim Y,Hotaling J

    更新日期:2018-05-01 00:00:00

  • Endometriosis and Female Pelvic Pain.

    abstract::Endometriosis is a nonmalignant gynecologic disorder that can have a significant impact on a woman's quality of life with pelvic pain and possible lasting effects on one's fertility. Symptoms, when present, can be severe and affect many organ systems including the gastrointestinal and urinary systems. Other etiologies...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0038-1676103

    authors: Kim JH,Han E

    更新日期:2018-03-01 00:00:00

  • Evaluation of a Center of Research Excellence in Polycystic Ovary Syndrome as a Large-Scale Collaborative Research Translation Initiative, Including Evaluating Translation of Guideline Impact.

    abstract::Research translation and evaluation are often underconsidered in research design and implementation thus limiting research benefit to the end user. In this article, we first describe a best practice approach to evaluation, for a center of research excellence in polycystic ovary syndrome. Within this, we outline a comp...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章

    doi:10.1055/s-0038-1667308

    authors: Garad R,Kozica-Olenski S,Teede HJ

    更新日期:2018-01-01 00:00:00

  • Lesbian Pregnancy: Care and Considerations.

    abstract::The constructs and the provision of preconception and obstetrical care have historically been based on the assumption of heterosexuality, and have often excluded lesbian women. However, due to significant strides in lesbian, gay, bisexual, transgender, and queer (LGBTQ) civil rights, more lesbian women desire to creat...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0037-1606385

    authors: Bushe S,Romero IL

    更新日期:2017-09-01 00:00:00

  • Developmental Origins of Hypothalamic Cells Controlling Reproduction.

    abstract::The hypothalamus-pituitary-gonadal (HPG) axis is the most critical modulator of reproductive function. Genetic or environmental insults to the HPG axis during developmental windows can persist into adulthood, and processes such as gonadal hormone synthesis, timing of puberty, and fertility can be affected. At the leve...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0037-1599083

    authors: Biehl MJ,Raetzman LT

    更新日期:2017-03-01 00:00:00

  • Medical Management of Endometriosis in Patients with Chronic Pelvic Pain.

    abstract::Endometriosis is a common cause of pelvic pain in women of reproductive age. Traditional medical therapies are hormonal in nature, including estrogen-progestin contraceptives, progestins, and gonadotropin-releasing hormone (GnRH) agonists. Other hormonal options are androgens and aromatase inhibitors, with research al...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0036-1597308

    authors: Bedaiwy MA,Allaire C,Yong P,Alfaraj S

    更新日期:2017-01-01 00:00:00

  • Management of Endometriosis Involving the Urinary Tract.

    abstract::Endometriosis is a common cause of infertility and disabling pelvic pain in reproductive age women. The most widely accepted theory of its pathogenesis is the retrograde flow of menstrual products, although extra-abdominal and extrapelvic diagnoses have been made. After the pelvic peritoneum and gynecologic structures...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0036-1597124

    authors: Ajao MO,Einarsson JI

    更新日期:2017-01-01 00:00:00

  • The Impact and Management of Subclinical Hypothyroidism for Improving Reproductive Outcomes such as Fertility and Miscarriage.

    abstract::Subclinical hypothyroidism has been found to be associated with adverse reproductive outcomes, such as infertility, miscarriage, preterm birth, and complications of pregnancy. Multiple studies have investigated the relationships between thyroid function, thyroid antibodies, fertility, and pregnancy. Thyroid autoimmuni...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0036-1593487

    authors: Seungdamrong A

    更新日期:2016-11-01 00:00:00

  • An Introduction to Genome-Wide Association Studies: GWAS for Dummies.

    abstract::Although the genetic origin of many human diseases and phenotypes has been long and widely recognized, identification of the causative gene alleles has been limited, slow, and cumbersome. This has changed substantially with the introduction of genome-wide association studies (GWASs) a decade ago, fueled by studies and...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章

    doi:10.1055/s-0036-1585406

    authors: Uitterlinden AG

    更新日期:2016-07-01 00:00:00

  • Contraception in the Developing World: Special Considerations.

    abstract::The United States Agency for International Development (USAID) estimates that there are 225 million women and girls with unmet contraceptive need yearly. Unmet need for contraception is defined as women who desire a delay in childbearing and are not using a modern method of contraception. It is projected that providin...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0036-1571437

    authors: Schivone GB,Blumenthal PD

    更新日期:2016-05-01 00:00:00

  • Complementary Therapies and Medicines and Reproductive Medicine.

    abstract::Complementary therapies and medicines are a broad and diverse range of treatments, and are frequently used by women and their partners during the preconception period to assist with infertility, and to address pregnancy-related conditions. Despite frequent use, the evidence examining the efficacy, effectiveness, and s...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0035-1571194

    authors: Smith CA,Armour M,Ee C

    更新日期:2016-03-01 00:00:00

  • Trophoblast Development in the Murine Preimplantation Embryo.

    abstract::Trophoblast cells of the murine placenta are derived from the trophectoderm (TE) cells of the preimplantation embryo. Establishment of the TE cell lineage is the result of a cell segregation event early in blastomere division. Models of cell lineage segregation suggest it is driven by the internalization of spatial in...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0035-1570025

    authors: Underhill LA,Robins JC

    更新日期:2016-01-01 00:00:00

  • Wnt Signaling in Stem Cells and Tumor Stem Cells.

    abstract::The Wnt signaling cascade is critically important in stem cell biology, both in homeostatic maintenance and repair and regeneration of tissues and organs, through their respective somatic stem cells (SSCs). However, aberrant Wnt signaling is associated with a wide array of tumor types and Wnt signaling is important in...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0035-1558404

    authors: Kahn M

    更新日期:2015-09-01 00:00:00

  • The Emerging Role of Chronic Low-Grade Inflammation in the Pathophysiology of Polycystic Ovary Syndrome.

    abstract::Polycystic ovary syndrome (PCOS) has become increasingly common over recent years and is associated with reproductive features as well as cardiometabolic risk factors, including visceral obesity, dyslipidemia and impaired glucose homeostasis, and potentially cardiovascular disease. Emerging evidence suggests that thes...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0035-1556568

    authors: Shorakae S,Teede H,de Courten B,Lambert G,Boyle J,Moran LJ

    更新日期:2015-07-01 00:00:00

  • The Role of a Mitochondrial Progesterone Receptor (PR-M) in Progesterone Action.

    abstract::Historically, progesterone functions to regulate gene expression via two nuclear progesterone receptors (PR-B and PR-A). Yet, actions of progesterone independent of gene regulation have been observed for decades. These are based on progesterone induced cellular events that occur too rapidly to involve gene transcripti...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0035-1552583

    authors: Price TM,Dai Q

    更新日期:2015-05-01 00:00:00

  • Human embryo cryopreservation-methods, timing, and other considerations for optimizing an embryo cryopreservation program.

    abstract::The contribution of embryo cryopreservation to the birth rate per in vitro fertilization cycle has escalated from a rare subsidy to a vital tool that is called upon to augment the cycle outcome. Embryology laboratories must identify the embryo stage, quality criteria and methodology that will optimize their ability to...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0035-1546826

    authors: Sparks AE

    更新日期:2015-03-01 00:00:00

  • Noncommunicable diseases.

    abstract::Noncommunicable diseases (NCDs), long considered diseases of little significance to global health, represent the greatest threat to economic development and human health. The main NCDs-diabetes, cancer, cardiovascular disease, and chronic respiratory disease-are the world's number one killer and bear the greatest burd...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章

    doi:10.1055/s-0034-1395277

    authors: Marrero S,Adashi EY

    更新日期:2015-01-01 00:00:00

  • Insights from the Women's Health Initiative: individualizing risk assessment for hormone therapy decisions.

    abstract::Identifying appropriate candidates for menopausal hormone therapy (HT) is challenging given the complex profile of risks and benefits associated with treatment. Most professional societies agree that HT should not be used for chronic disease prevention. Recent findings from the Women's Health Initiative and other rand...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0034-1384626

    authors: Wild RA,Manson JE

    更新日期:2014-11-01 00:00:00

  • Cyclic remodeling of the nonhuman primate endometrium: a model for understanding endometrial receptivity.

    abstract::Old World monkeys display physiological responses to steroid hormones that are similar to those of women. In this review, we describe cyclic morphological changes that take place within the uterus of Old World primates during the menstrual cycle. In primates, estrogen stimulates endometrial growth in the follicular ph...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0034-1376357

    authors: Slayden OD

    更新日期:2014-09-01 00:00:00

  • Indications of intrauterine insemination for male and non-male factor infertility.

    abstract::Intrauterine insemination (IUI) is a widely used fertility treatment for couples with male and/or non-male factor infertility and is a relatively simple and inexpensive procedure. When used for unexplained infertility, IUI combined with ovarian stimulation increases the pregnancy rates, but evidence does not support t...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0034-1375183

    authors: Kim YJ,Park CW,Ku SY

    更新日期:2014-07-01 00:00:00

  • Intrauterine environment and polycystic ovary syndrome.

    abstract::The maternal-fetal environment plays an important role in developmental programming of adult disease. Metabolic and hormonal dysfunction during human fetal development accompanies gestational diabetes as a common occurrence in mothers with polycystic ovary syndrome (PCOS), while human fetal androgen excess from congen...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0034-1371087

    authors: Dumesic DA,Goodarzi MO,Chazenbalk GD,Abbott DH

    更新日期:2014-05-01 00:00:00

  • Microbiota and pelvic inflammatory disease.

    abstract::Female genital tract microbiota play a crucial role in maintaining health. Disequilibrium of the microbiota has been associated with increased risk of pelvic infections. In recent years, culture-independent molecular techniques have expanded understanding of the composition of genital microbiota and the dynamic nature...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0033-1361822

    authors: Sharma H,Tal R,Clark NA,Segars JH

    更新日期:2014-01-01 00:00:00

  • Oocyte development and loss.

    abstract::Soon after implantation, cell lineages bifurcate into future somatic and germ cells. Canonical expression of germ cell-specific genes continues during and after their migration to the gonadal ridge, where, after further cell cycles, they enter meiosis, form syncytial clusters, and arrest at diplotene for folliculogene...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0033-1356475

    authors: Gosden RG

    更新日期:2013-11-01 00:00:00

  • Big enough for an aromatase inhibitor? How adiposity affects male fertility.

    abstract::Obesity is a pandemic and is associated with multiple medical problems including subfertility. Male obesity has been associated with altered semen parameters and reproductive hormonal levels, including a reduced testosterone:estradiol (T:E₂) ratio. Treatment methods employed for obesity-related male subfertility inclu...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0033-1345272

    authors: Stephens SM,Polotsky AJ

    更新日期:2013-07-01 00:00:00

  • Money-back guarantees.

    abstract::As fertility rates among women of advanced reproductive age have steadily increased, so has the utilization of fertility services. National health policies provide infertility treatment coverage in several developed countries; however, in the United States infertility treatment is largely privately funded, resulting i...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章

    doi:10.1055/s-0033-1336600

    authors: Levens ED,Richter KS,Levy MJ

    更新日期:2013-05-01 00:00:00

  • Role of surgery in endometriosis-associated subfertility.

    abstract::Analysis of published series reveals that no more than a fourth of subfertile patients undergoing surgery for peritoneal endometriotic implants, rectovaginal endometriotic lesions, or recurrent endometriomas achieved conception spontaneously. First-line surgery for ovarian endometriotic cysts appears associated with a...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0032-1333478

    authors: Berlanda N,Vercellini P,Somigliana E,Frattaruolo MP,Buggio L,Gattei U

    更新日期:2013-03-01 00:00:00

  • Somatic stem cells in the myometrium and in myomas.

    abstract::The human uterus mainly consists of two layers: an inner endometrium and an outer layer, the myometrium, made of smooth muscle. The uterus is characterized by its unique capacity for regeneration. This capacity permits cyclical regeneration and remodeling of the tissue over the course of a woman's reproductive life. D...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0032-1331801

    authors: Maruyama T,Ono M,Yoshimura Y

    更新日期:2013-01-01 00:00:00

  • The impact of bariatric surgery on obesity-related infertility and in vitro fertilization outcomes.

    abstract::Obesity-related infertility is one of the most common problems of reproductive-age obese women who desire childbearing. The various types of bariatric surgeries have proved effective in controlling excessive weight gain, improving fertility, and preventing certain maternal and fetal complications in these women. This ...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0032-1328880

    authors: Tan O,Carr BR

    更新日期:2012-12-01 00:00:00

  • Advice on the management of ambiguous genitalia to a young endocrinologist from experienced clinicians.

    abstract::The birth of a child with ambiguous genitalia is a challenging and distressing event for the family and physician and one with life-long consequences. Most disorders of sexual differentiation (DSD) associated with ambiguous genitalia are the result either of inappropriate virilization of girls or incomplete virilizati...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0032-1324717

    authors: Wilson JD,Rivarola MA,Mendonca BB,Warne GL,Josso N,Drop SL,Grumbach MM

    更新日期:2012-10-01 00:00:00

  • DSD due to 5α-reductase 2 deficiency - from diagnosis to long term outcome.

    abstract::Most of the patients with 5α-RD 2 deficiency are reared in the female social sex due to their severely undervirilized external genitalia but ~60% who have not been submitted to orchiectomy in childhood undergo male social sex change at puberty. In our cohort of 30 cases from 18 families, all subjects were registered i...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0032-1324727

    authors: Costa EM,Domenice S,Sircili MH,Inacio M,Mendonca BB

    更新日期:2012-10-01 00:00:00

  • Aneuploidy screening for embryo selection.

    abstract::Chromosome abnormalities are extremely common in human oocytes and embryos and are associated with a variety of negative outcomes for both natural cycles and those using assisted conception techniques. Embryos containing the wrong number of chromosomes (aneuploidy) may fail to implant in the uterus, miscarry, or lead ...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0032-1313908

    authors: Fragouli E,Wells D

    更新日期:2012-08-01 00:00:00

  • Does the European Union Tissues and Cells Directive improve quality in the in vitro fertilization laboratory? A case study in a tertiary referral center.

    abstract::Since 2004, assisted conception is encompassed by the European Directive on the Quality and Safety of Tissues and Cells (2004/23/EC). The aim of a standard for quality and safety is to minimize risks of errors, contamination, and accidents and to maximize efficiency of use. This article presents a case study of the im...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章

    doi:10.1055/s-0032-1311521

    authors: Willemen D,D'Hooghe T,Knoops I,De Neubourg D,Spiessens C

    更新日期:2012-06-01 00:00:00

  • Genetic disorders related to male factor infertility and their adverse consequences.

    abstract::Assisted reproductive techniques have revolutionized the treatment of male reproductive failure, allowing biological fatherhood to be achieved by many men that nature would have never permitted. As we are able to help more and more couples with our therapies, the genetic basis of the man's spermatogenic, anatomical, o...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0032-1307418

    authors: Harnisch B,Oates R

    更新日期:2012-04-01 00:00:00

  • Tissue-specific regulation of genes by estrogen receptors.

    abstract::Estrogens are frequently used in reproductive medicine. The Women's Health Initiative trial found that the risks of menopausal hormone therapy (MHT) exceed the benefits. The estrogens in MHT, however, were introduced prior to our understanding of the mechanism of action of estrogens. Estrogen signaling is highly compl...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1299593

    authors: Leitman DC,Paruthiyil S,Yuan C,Herber CB,Olshansky M,Tagliaferri M,Cohen I,Speed TP

    更新日期:2012-01-01 00:00:00

  • Management of recurrent pregnancy loss associated with a parental carrier of a reciprocal translocation: a systematic review.

    abstract::This study reviews systematically the effectiveness of management strategies for carriers of a reciprocal translocation involving two chromosomes, ascertained on the basis of recurrent pregnancy loss. Subsequent pregnancy outcomes were tabulated based on whether management was medical or involved in vitro fertilizatio...

    journal_title:Seminars in reproductive medicine

    pub_type: 杂志文章,评审

    doi:10.1055/s-0031-1293201

    authors: Hirshfeld-Cytron J,Sugiura-Ogasawara M,Stephenson MD

    更新日期:2011-11-01 00:00:00

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