abstract：:The risk of malignant arrhythmias is higher during extremely intense exercise and after its cessation. It is still unclear whether high-intensity interval exercise (HIE), an increasingly popular option in preventive and rehabilitative medicine, can lead to an impaired electrophysiological milieu, as revealed by QT int...

journal_title：Herz

authors： Nie J,Shi Q,Kong Z,Lao CK,Zhang H,Tong TK

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Limited data exist on bioresorbable scaffolds (BRS) in patients with acute coronary syndrome (ACS). The aim of the present study was to evaluate novolimus-eluting BRS (DESolve) as interventional treatment for patients with ACS, and to compare its 12-month outcomes with the everolimus-eluting bioresorbable sc...

journal_title：Herz

authors： Nef HM,Wiebe J,Schmidt G,Möllmann H,Boeder NF,Dörr O,Bauer T,Blachutzik F,Liebetrau C,Elsässer A,Foin N,Hamm CW

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Elevated levels of the extracellular matrix glycoprotein osteopontin (OPN) may be detected in both myocardium and plasma under various pathological conditions affecting the heart. Several studies demonstrated increased plasma OPN levels in patients with heart failure due to dilated cardiomyopathy (DCM), whil...

journal_title：Herz

authors： Podzimkova J,Palecek T,Kuchynka P,Marek J,Danek BA,Jachymova M,Safarikova M,Kalousova M,Zima T,Linhart A

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:We aimed to investigate the predictive value of the fibrinogen-to-albumin ratio (FAR) regarding the development of major cardiovascular events (MACE) in patients treated with percutaneous coronary intervention (PCI) for acute coronary syndrome (ACS). METHODS:This was a prospective, observational cohort stud...

journal_title：Herz

authors： Çetin M,Erdoğan T,Kırış T,Özer S,Yılmaz AS,Durak H,Aykan AÇ,Şatıroğlu Ö

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVES:Endothelial dysfunction is involved in various aspects of vascular biology and different stages of cardiovascular diseases (CVDs). Nucleotide-binding oligomerization domain-containing protein (NOD) 2, a pivotal innate immune receptor for muramyl dipeptide (MDP), has been reported to be a central regulator in...

journal_title：Herz

authors： Kong LJ,Wang YN,Wang Z,Lv QZ

更新日期：2020-11-27 00:00:00

abstract：BACKGROUND:Atrial remodeling in the form of fibrosis is considered the basis in the development of atrial fibrillation (AF). The aim of this study was to investigate the effects of doxycycline on atrial remodeling induced by chronic intermittent hypoxia (CIH) and the mechanisms underlying such changes. METHODS:A total...

journal_title：Herz

authors： Zhang K,Ma Z,Wang W,Liu R,Zhang Y,Yuan M,Li G

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Postcardiac injury syndrome (PCIS) is an inflammatory complication that derives from injury to the epicardium, myocardium, or endocardium. It occurs after trauma, myocardial infarction, percutaneous coronary intervention, cardiac surgery, intracardiac ablation, and implantation of cardiac implantable electro...

journal_title：Herz

authors： Filbey K,Sedaghat-Hamedani F,Kayvanpour E,Xynogalos P,Scherer D,Meder B,Katus HA,Zitron E

更新日期：2020-11-01 00:00:00

abstract：:Oncocardiology is an emerging field in cardiovascular healthcare. Besides establishing surveillance and follow-up strategies for cancer patients, it will be essential to set up specialized oncocardiology services. However, there is a lack of clinical studies to give evidence-based recommendations regarding cardiologic...

journal_title：Herz

authors： Lehmann LH,Totzeck M

更新日期：2020-11-01 00:00:00

abstract：:The progress in cardiology during the last 50 years can best be studied by looking at the diagnostics and treatment of patients with aortic valve stenosis. Previously, the clinical examination, electrocardiography (ECG) and chest X‑ray were used before heart catheterization, which included a transseptal puncture to co...

journal_title：Herz

authors： Erbel R

更新日期：2020-11-01 00:00:00

abstract：:The 4th edition of the Universal Definition of Myocardial Infarction (MI) recommends measurement of cardiac troponin (cTn) T or I for the diagnosis of MI due to their absolute cardiac tissue specificity. In this MI definition, values exceeding the 99th percentile of a healthy reference population distinguish between d...

journal_title：Herz

authors： Giannitsis E,Gopi V

更新日期：2020-09-01 00:00:00

abstract：:The European Society of Cardiology (ESC) has recently published new guidelines on the diagnosis and management of chronic coronary syndromes (CCS). Due to variable symptoms, objective tests are often necessary to confirm the diagnosis, exclude alternative diagnoses, and assess the severity of underlying disease. This ...

journal_title：Herz

authors： Saraste A,Knuuti J

更新日期：2020-08-01 00:00:00

abstract：:Routine determination of troponin levels is recommended for all patients with acute ischemic stroke. In 20-55% of these patients the troponin levels are elevated, which may be caused by ischemic as well as non-ischemic myocardial damage and particularly neurocardiogenic myocardial damage. In patients with acute ischem...

journal_title：Herz

authors： Kruska M,Fastner C,Scheitz JF,Kolb A,Rutsch M,Papavassiliu T,Borggrefe M,Alonso A,Akin I,Szabo K,Baumann S

更新日期：2020-07-06 00:00:00

abstract：OBJECTIVES:Little is known about cardiac involvement in m.3243A>G variant carriers. Thus, this study aimed to assess type and frequency of cardiac disease in symptomatic and asymptomatic m.3243A>G carriers. METHODS:Systematic literature review. RESULTS:The m.3243A>G variant may manifest phenotypically as mitochondria...

journal_title：Herz

authors： Finsterer J,Zarrouk-Mahjoub S

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:In the present study, the electropharmacological activity of traditional Chinese medicine, Ginkgo biloba extract (GBE), on human hyperpolarization-activated nucleotide-gated (HCN) channels and the underlying "funny" currents was investigated. METHODS:Standard two-electrode voltage-clamp recordings were empl...

journal_title：Herz

authors： Chen H,Chen Y,Yang J,Wu P,Wang X,Huang C

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:This study aimed to investigate the impact of metabolic syndrome (MetS) with microalbuminuria on the improvement of cardiac function after acute myocardial infarction (AMI). METHODS:Nondiabetic patients with acute ST segment elevation MI (STEMI) who underwent coronary revascularization from 2013 to 2017 wer...

journal_title：Herz

authors： Jin L,Cai S,Qian J,Ma H,Chen W,Li G,Ge X,Fan X,Fu L

更新日期：2020-05-11 00:00:00

abstract：:With increasing age valvular heart disease is among the most frequent diseases of the heart. Relevant valvular disease impairs not only the long-term prognosis but also physical resilience, activities of daily living and the quality of life. In cases of middle to high-grade symptomatic cardiac defects, valve replaceme...

journal_title：Herz

authors： Nechwatal RM,Bestehorn K,Leuschner F,Hagendorff A,Guha M,Schlitt A

更新日期：2020-04-20 00:00:00

abstract：:Heart failure is one of the leading diseases in internal medicine worldwide. Because of the increase in population aging, the incidence and prevalence of heart insufficiency is rising annually and is now the most frequent individual diagnosis among hospitalized patients in Germany. The mortality rate has recently been...

journal_title：Herz

authors： Wintrich J,Kindermann I,Böhm M

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The most common cause of procedural failure in cardiac catheterization using the transradial approach is radial artery spasm. The aim of this study was to compare the procedural success rate of the 6‑Fr Glidesheath Slender with the 6‑Fr standard sheath in transradial coronary angiography and intervention. M...

journal_title：Herz

authors： Gul B,Stolar M,Stair B,Hermany P,Willis S,Mena-Hurtado C,Attaran R

更新日期：2020-02-01 00:00:00

abstract：:Cardiovascular (CV) risk assessment is based on the utilization of risk scores, enabling clinicians to estimate an individual's risk to develop CV pathologies and events. Such risk scores comprise classic CV risk factors such as smoking, diabetes, hypertension, and blood cholesterol levels. Recently, other CV biomarke...

journal_title：Herz

authors： Schulte C,Zeller T

更新日期：2020-02-01 00:00:00

abstract：:Cardiovascular diseases are the leading cause of death worldwide. Adherence to a healthy lifestyle lifelong is capable of significantly reducing the cardiovascular risk by up to 70% and is therefore a key component in primary prevention of cardiovascular disease. According to the European and American guidelines lifes...

journal_title：Herz

authors： Heinicke V,Halle M

更新日期：2020-02-01 00:00:00

abstract：:Unexplained sudden death in the young is cardiovascular in most cases. Structural and conduction defects in cardiac-related genes can conspire to underlie sudden cardiac death. Here we report a clinical investigation and an extensive genetic assessment of a Tunisian family with sudden cardiac death in young members. I...

journal_title：Herz

authors： Jaouadi H,Bouyacoub Y,Chabrak S,Kraoua L,Zaroui A,Elouej S,Nagara M,Dallali H,Delague V,Levy N,Benkhalifa R,Mechmeche R,Zaffran S,Abdelhak S

更新日期：2020-01-22 00:00:00

abstract：BACKGROUND:In addition to the genetic complexity of hypertrophic cardiomyopathy (HCM), there must be other disease-modifying factors that contribute to its highly variable clinical and phenotypic expression. The authors aimed to investigate serum thiol/disulphide homeostasis as a proxy for oxidative stress using a nove...

journal_title：Herz

authors： Sari M,Erkorkmaz U,Yazar H,Kocayigit I,Omar B,Alizade E,Aksoy MNM,Uslu A,Cakar GC,Pala S

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:The polymer-free biolimus-A9 drug-coated stent (DCS) was reported to have superior safety and efficacy outcomes compared with a bare metal stent in the LEADERS FREE trial of high-bleeding-risk patients with acute coronary syndrome and on dual antiplatelet treatment (DAPT) for 1 month. The aim of this investi...

journal_title：Herz

authors： Lee DJH,Loh JKK,Jafary FH,Ho HH,Watson T,Stoll HP,Ong PJL

更新日期：2019-12-01 00:00:00

abstract：:Geminin, a key regulator of DNA replication licensing in the cell cycle, plays an essential role in determining the fate of cells via suppression of cell proliferation and cellular differentiation. Neuropeptide Y (NPY) intensifies the proliferation of vascular smooth muscle cells (VSMCs) directly by binding with Y1 re...

journal_title：Herz

authors： Liang SY,Zhou YL,Shu MQ,Lin S

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:Cardiovascular magnetic resonance imaging (CMR) has been established as a modality to detect myocardial viability. The aim of this study was to evaluate myocardial viability by observing transmural extent of infraction and microvascular perfusion level. METHODS:We performed CMR in 30 myocardial infarction (M...

journal_title：Herz

authors： Sun W,Sun L,Yang F,Zhao X,Cai R,Yuan W

更新日期：2019-12-01 00:00:00

abstract：:After an unusually long period of time of 6 years, in August 2019 the updated version of the European Society of Cardiology (ESC) guidelines from 2013 on the management of stable coronary artery disease was published. The course of "stable" coronary artery disease is only assumed to be stable and pathologically is oft...

journal_title：Herz

authors： Silber S

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The expansion of the transcatheter aortic valve replacement (TAVR) indication towards patients with intermediate surgical risk (Ref. Society of Thoracic Surgeons, STS, score) was analyzed. The aim was to investigate if the complication rates particularly with respect to TAVR and surgical aortic valve replace...

journal_title：Herz

authors： Barth U

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Renal denervation (RDN) has been proposed as a novel antihypertensive intervention for treating resistant hypertension. It remains to be investigated which patient groups can potentially benefit from RDN. The present study aimed to evaluate the efficacy and safety of RDN in patients with mild-moderate resist...

journal_title：Herz

authors： Chen S,Kiuchi MG,Schmidt B,Hoye NA,Acou WJ,Liu S,Chun KRJ,Pürerfellner H

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the prognostic value of restrictive right ventricular filling pattern (RRVFP) in patients with the first acute inferior wall myocardial infarction (IWMI) complicated by right ventricular myocardial infarction (RVMI) undergoing primary percutaneous coronary interventio...

journal_title：Herz

authors： Altıntaş B,Yaylak B,Ede H,Altındağ R,Baysal E,Bilge Ö,Çiftçi H,Adıyaman MŞ,Karahan MZ,Kaya I,Çevik K

更新日期：2019-04-01 00:00:00

abstract：:Independent of the underlying cause, pulmonary hypertension (PH) remains a devastating condition that is characterized by limited survival. Cumulating evidence indicates that in addition to a dysbalance of mediators regulating vascular tone and growth factors promoting vascular remodeling, failure to resolve inflammat...

journal_title：Herz

authors： Berghausen EM,Feik L,Zierden M,Vantler M,Rosenkranz S

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:The angiographic slow/no-reflow phenomenon after primary percutaneous coronary intervention carries a poor prognosis for patients with non-ST-segment elevation acute coronary syndrome (NSTEACS). There is evidence that contrast agents cause endothelial dysfunction, myocardial cell damage, and coronary spasms....

journal_title：Herz

authors： Ding S,Shi Y,Sun X,Cao Q,Dai H,Guan J

更新日期：2019-02-01 00:00:00

abstract：:The current guidelines of the European Society of Cardiology have up-dated and confirmed the role of a primary percutaneous coronary intervention (PCI) as the preferred reperfusion therapy in patients with acute coronary syndrome and ST-elevation. The establishment of regional network structures for implementation of ...

journal_title：Herz

authors： Haude M,Rupprecht HJ,Schuster S,Uebis R

更新日期：2019-02-01 00:00:00

abstract：:The guidelines on myocardial revascularization published in 2018 are a joint initiative of the European Society of Cardiology and the European Association for Cardio-Thoracic Surgery. To establish indications for myocardial revascularization by percutaneous coronary intervention (PCI) or coronary artery bypass graftin...

journal_title：Herz

authors： Neumann FJ,Hochholzer W,Siepe M

更新日期：2018-12-01 00:00:00

abstract：:Certification is a critical component of quality assurance in medicine. From the certification of individual persons, through units and up to whole hospitals, certification stimulates testing and optimization of treatment processes, thereby improving the quality of care. Minimum case numbers needed to acquire a certif...

journal_title：Herz

authors： Halbach M,Baldus S

更新日期：2018-09-01 00:00:00

abstract：:Exertional dyspnea is a nonspecific symptom with a variety of underlying causes. It can be challenging to differentiate a beginning cardiac disease from a pulmonary disease or from deconditioning alone. In the presence of obesity, the overall assessment is even more difficult. Rare diseases, such as pulmonary hyperten...

journal_title：Herz

authors： Wilkens H,Held M

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Inducible nitric oxide synthase (iNOS) single-nucleotide polymorphisms have been reported to confer susceptibility to hypertension, but no consensus has been reached. The aim of this study was to investigate the association between iNOS and hypertension in a Chinese population. METHODS:This was a case-contr...

journal_title：Herz

authors： Zhai Z,Wang Z,Wang L,Chen S,Ren H,Wang D

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:It is not known whether older patients with acute heart failure (HF) receiving tolvaptan have decreased mortality rates and a better long-term prognosis than patients who receive furosemide. We conducted a systematic review of randomized controlled trials (RCTs) to address this issue. METHODS:The Medline, E...

journal_title：Herz

authors： Huang WL,Yang Y,Yang J,Yang J,Wang HB,Xiong XL,Zhang YF

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Galectin-3 has been reported as a mediator of heart failure (HF) development and progression. Most studies, however, have been conducted on patients with chronic HF rather than acute HF (AHF). The aim of this study was to confirm galectin-3 as a prognostic marker in subjects with AHF and to investigate its p...

journal_title：Herz

authors： Lala RI,Lungeanu D,Darabantiu D,Pilat L,Puschita M

更新日期：2018-03-01 00:00:00

abstract：:The 12-lead surface electrocardiogram (ECG) is of great importance for the diagnostics of cardiac arrhythmias. For the correct and systematic analysis it has a sensitivity and specificity for the correct diagnosis of supraventricular tachycardia or ventricular tachycardia of more than 95%. Nevertheless, the assessment...

journal_title：Herz

authors： Trappe HJ

更新日期：2018-03-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most frequently encountered sustained arrhythmia with a prevalence of 0.5-10%, depending predominantly on age. The arrhythmia is associated with significant morbidity and mortality, mainly due to thromboembolic events including stroke and systemic embolisms. These complications can be e...

journal_title：Herz

authors： Erath JW,Hohnloser SH

更新日期：2018-02-01 00:00:00