听力与言语-语言病理学

行为科学

医学伦理学

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  • Prevalence and risk factors for Pulmonary Hypertension associated with chronic Myeloproliferative Neoplasms.

    abstract:OBJECTIVES:Pulmonary hypertension (PH) is commonly reported in Philadelphia-chromosome negative myeloproliferative neoplasms (MPNs) including polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF). PH may be diagnosed directly by right heart catheterization (RHC) or estimated by transthoracic ec...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13543

    authors: Ferrari A,Scandura J,Masciulli A,Krichevsky S,Gavazzi A,Barbui T

    更新日期:2021-02-01 00:00:00

  • Treating Secondary Antibody Deficiency in Patients with Haematological Malignancy: European Expert Consensus.

    abstract:OBJECTIVES:Secondary antibody deficiency (SAD), associated with severe, recurrent or persistent infections, is common in patients with haematological malignancies (HM), but unifying guidance on immunoglobulin replacement therapy (IgRT) in these patients is lacking. We aimed to develop consensus statements for the use o...

    journal_title:European journal of haematology

    pub_type: 杂志文章,评审

    doi:10.1111/ejh.13580

    authors: Jolles S,Michallet M,Agostini C,Albert MH,Edgar D,Ria R,Trentin L,Lévy V

    更新日期:2021-01-16 00:00:00

  • Outcomes of relapsed or refractory acute myeloid leukemia patients failing venetoclax-based salvage therapies.

    abstract:OBJECTIVES AND METHODS:We conducted a retrospective analysis to evaluate the outcomes of 28 heavily pretreated (median 3 (2-6) treatment lines, sixteen (57%) allotransplanted) relapsed/refractory acute myeloid leukemia patients who had failed salvage venetoclax-based therapies. RESULTS:The median age was 59 years (20-...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13527

    authors: Zucenka A,Pileckyte R,Trociukas I,Peceliunas V,Vaitekenaite V,Maneikis K,Davainis L,Zvirblis T,Stoskus M,Gineikiene E,Norvilas R,Dirse V,Surauciute A,Zucenkiene E,Griskevicius L

    更新日期:2021-01-01 00:00:00

  • Impact of a comprehensive geriatric assessment on decision making in older patients with hematologic malignancies.

    abstract:OBJECTIVE:Hematological treatment decisions in older adults with hematological malignancies are complex. Our objective is to study the impact of a comprehensive geriatric assessment on hematological treatment decision in older patients and the factors associated with change in treatment plan. METHODS:We conducted a cr...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13570

    authors: Garric M,Sourdet S,Cabarrou B,Steinmeyer Z,Gauthier M,Ysebaert L,Beyne-Rauzy O,Gerard S,Lozano S,Brechemier D,Filleron T,Mourey L,Balardy L

    更新日期:2020-12-19 00:00:00

  • Vitamin E and acute graft-versus-host disease after myeloablative allogeneic hematopoietic cell transplantation.

    abstract:OBJECTIVES:Vitamin E has antioxidant and immunomodulatory effects that might influence the development of acute graft-versus-host disease (GvHD). We investigated the association between plasma vitamin E levels and acute GvHD. METHODS:We studied 115 adults who underwent myeloablative allogeneic hematopoietic cell trans...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13567

    authors: Gjaerde LK,Ostrowski SR,Minculescu L,Andersen NS,Friis LS,Kornblit B,Petersen SL,Schjødt I,Sengeløv H

    更新日期:2020-12-12 00:00:00

  • The hematologic consequences of obesity.

    abstract::The prevalence of obesity is increasing and progressively influencing physician-patient interactions. While there is a sizable amount of data demonstrating that obesity is a state of low-grade inflammation, to our knowledge, there is no single review summarizing its effects on hematologic parameters and thrombotic ris...

    journal_title:European journal of haematology

    pub_type: 杂志文章,评审

    doi:10.1111/ejh.13560

    authors: Purdy JC,Shatzel JJ

    更新日期:2020-12-03 00:00:00

  • COVID-19 coagulopathy: An in-depth analysis of the coagulation system.

    abstract:BACKGROUND:Abnormal coagulation parameters have been reported in COVID-19-infected patients. Although the underlying mechanism of COVID-19 coagulopathy remains unknown, it has been suggested to be a form of disseminated intravascular coagulation (DIC). OBJECTIVES:The aim of our study was to analyze the coagulation par...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13501

    authors: Martín-Rojas RM,Pérez-Rus G,Delgado-Pinos VE,Domingo-González A,Regalado-Artamendi I,Alba-Urdiales N,Demelo-Rodríguez P,Monsalvo S,Rodríguez-Macías G,Ballesteros M,Osorio-Prendes S,Díez-Martín JL,Pascual Izquierdo C

    更新日期:2020-12-01 00:00:00

  • Emicizumab treatment: Impact on coagulation tests and biological monitoring of haemostasis according to clinical situations (BIMHO group proposals).

    abstract::Emicizumab, a bispecific humanised monoclonal antibody restoring to some extent the function of activated FVIII deficient in haemophilia A, represents a major therapeutic advance in the management of haemophilia A patients. No dosage adjustment is required, which leads to a major change for patients used to regular bi...

    journal_title:European journal of haematology

    pub_type: 杂志文章,评审

    doi:10.1111/ejh.13490

    authors: Nougier C,Jeanpierre E,Ternisien C,Proulle V,Hezard N,Pouplard C,Lasne D,With contributions from the Working Group on Biology of Haemorrhagic Disorders (BIMHO, Under the Aegis of GFHT).

    更新日期:2020-12-01 00:00:00

  • Real-world outcomes for 205 patients with chronic lymphocytic leukemia treated with ibrutinib.

    abstract::Ibrutinib has now been approved for treatment of chronic lymphocytic leukemia (CLL) in both front-line setting and as later-line treatment. However, knowledge about the outcomes and adverse events (AE) among patients at a population-based level is still limited. OBJECTIVES:To report outcomes and AEs in a population-b...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13499

    authors: Aarup K,Rotbain EC,Enggaard L,Pedersen RS,Bergmann OJ,Thomsen RH,Frederiksen M,Frederiksen H,Nielsen T,Christiansen I,Andersen MA,Niemann CU

    更新日期:2020-11-01 00:00:00

  • Lenalidomide as maintenance treatment for patients with multiple myeloma after autologous stem cell transplantation: A pharmaco-economic assessment.

    abstract:OBJECTIVE:Autologous stem cell transplantation (ASCT) has improved progression-free survival (PFS) and overall survival in eligible patients with newly diagnosed multiple myeloma (NDMM); however, relapse occurs. Maintenance therapy with lenalidomide (Len-Mt) extends survival and delays relapse and the subsequent initia...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13497

    authors: Uyl-de Groot CA,Ramsden R,Lee D,Boersma J,Zweegman S,Dhanasiri S

    更新日期:2020-11-01 00:00:00

  • A population-based study on serious inpatient bacterial infections in patients with chronic lymphocytic leukemia and their impact on survival.

    abstract:OBJECTIVE:Infections in chronic lymphocytic leukemia (CLL) have been thoroughly investigated in the setting of clinical trials and single-center studies. However, large cohort studies on real-world data and studies on temporal trends are lacking. We performed a nationwide study on serious bacterial infections in CLL. ...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13477

    authors: Steingrímsson V,Gíslason GK,Aspelund T,Turesson I,Björkholm M,Landgren O,Kristinsson SY

    更新日期:2020-11-01 00:00:00

  • Clinical course and risk factors for mortality from COVID-19 in patients with haematological malignancies.

    abstract:BACKGROUND:The impact of coronavirus disease 2019 (COVID-19) in haematological patients (HP) has not been comprehensively reported. METHODS:We analysed 39 patients with SARS-CoV-2 infection and haematological malignancies. Clinical characteristics and outcomes were compared to a matched control group of 53 non-cancer ...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13493

    authors: Sanchez-Pina JM,Rodríguez Rodriguez M,Castro Quismondo N,Gil Manso R,Colmenares R,Gil Alos D,Paciello ML,Zafra D,Garcia-Sanchez C,Villegas C,Cuellar C,Carreño-Tarragona G,Zamanillo I,Poza M,Iñiguez R,Gutierrez X,Alonso R

    更新日期:2020-11-01 00:00:00

  • Anagrelide influences thrombotic risk, and prolongs progression-free and overall survival in essential thrombocythaemia vs hydroxyurea plus aspirin.

    abstract:OBJECTIVE:We report an extension study of patients with essential thrombocythaemia (ET) in the Hungarian Myeloproliferative Neoplasm (HUMYPRON) Registry, which demonstrated that over 6 years anagrelide significantly decreased the number of patients experiencing minor arterial and minor venous thrombotic events (TEs) vs...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13459

    authors: Kellner A,Dombi P,Illes A,Demeter J,Homor L,Ercsei I,Simon Z,Karadi E,Herczeg J,Gy Korom V,Gasztonyi Z,Szerafin L,Udvardy M,Egyed M

    更新日期:2020-10-01 00:00:00

  • Patient outcomes in light chain (AL) amyloidosis: The clock is ticking from symptoms to diagnosis.

    abstract:INTRODUCTION:Symptomology of AL amyloidosis can be vague, with a broad range of manifestations and potential etiologies. We sought to determine whether time from initial patient-reported symptom onset to diagnosis was associated with survival. METHODS:The Boston University Amyloidosis Patient Database was queried for ...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13472

    authors: Schulman A,Connors LH,Weinberg J,Mendelson LM,Joshi T,Shelton AC,Sanchorawala V

    更新日期:2020-10-01 00:00:00

  • Primary pancreatic lymphoma: Clinical presentation, diagnosis, treatment, and outcome.

    abstract::Primary pancreatic lymphoma (PPL) is a rare disease representing 0.1% of malignant lymphomas, which lacks well-defined diagnostic and therapeutic protocols. OBJECTIVES:To describe PPL clinical, diagnostic and histological characteristics, together with therapy and outcome, in a relatively large series of patients. M...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13468

    authors: Facchinelli D,Sina S,Boninsegna E,Borin A,Tisi MC,Piazza F,Scapinello G,Maiolo E,Hohaus S,Zamò A,Merli M,Stefani PM,Mellone F,Basso M,Sartori R,Rusconi C,Parisi A,Manfrin E,Krampera M,Ruggeri M,Visco C,Tecchio C

    更新日期:2020-10-01 00:00:00

  • Causes of hypereosinophilia in 100 consecutive patients.

    abstract:BACKGROUND:Hypereosinophilia (HE, persistent peripheral blood eosinophilia > 1.5 × 109 /L) and hypereosinophilic syndrome (HES, HE with end-organ damage) are classified as primary (due to a myeloid clone), secondary (due to a wide variety of reactive causes), or idiopathic. Diagnostic evaluation of eosinophilia is chal...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13437

    authors: Moller D,Tan J,Gauiran DTV,Medvedev N,Hudoba M,Carruthers MN,Dehghan N,van den Berghe J,Bruyère H,Chen LYC

    更新日期:2020-09-01 00:00:00

  • Circulating extracellular vesicle-associated CD163 and CD206 in multiple myeloma.

    abstract:OBJECTIVES:Extracellular vesicles (EVs) are important for intercellular signalling in cancer. Tumour-associated macrophages, expressing the haemoglobin-haptoglobin and mannose receptors CD163 and CD206, are crucial for cancer progression. We recently identified CD163 on EVs in the circulation as a fraction of total sol...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13371

    authors: Kvorning SL,Nielsen MC,Andersen NF,Hokland M,Andersen MN,Møller HJ

    更新日期:2020-05-01 00:00:00

  • Bridging antifungal prophylaxis with 50 mg or 100 mg micafungin in allogeneic stem cell transplantation: A retrospective analysis.

    abstract:OBJECTIVE:Fluconazole or posaconazole is a standard of care in antifungal prophylaxis for patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT). However, many patients need to interrupt standard prophylaxis due to intolerability, drug-drug interactions, or toxicity. Micafungin has come to promin...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13372

    authors: Rothe A,Claßen A,Carney J,Hallek M,Mellinghoff SC,Scheid C,Holtick U,von Bergwelt-Baildon M

    更新日期:2020-04-01 00:00:00

  • Rivaroxaban versus apixaban in non-valvular atrial fibrillation patients with end-stage renal disease or receiving dialysis.

    abstract:OBJECTIVES:We sought to evaluate the effectiveness and safety of rivaroxaban vs apixaban in non-valvular atrial fibrillation (NVAF) patients with end-stage renal disease (ESRD) and/or receiving dialysis in routine practice. METHODS:Using US MarketScan claims data from January 1, 2014, to December 31, 2017, we identifi...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13383

    authors: Miao B,Sood N,Bunz TJ,Coleman CI

    更新日期:2020-04-01 00:00:00

  • B cell maturation antigen-specific chimeric antigen receptor T cells for relapsed or refractory multiple myeloma: A meta-analysis.

    abstract:INTRODUCTION:Chimeric antigen receptor (CAR) T cells targeting B cell maturation antigen (BCMA) have shown impressive results in clinical studies for relapsed/refractory multiple myeloma (RRMM). We performed a systematic literature review to summarize the current body of evidence on the role of anti-BCMA CAR T cells fo...

    journal_title:European journal of haematology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/ejh.13380

    authors: Gagelmann N,Ayuk F,Atanackovic D,Kröger N

    更新日期:2020-04-01 00:00:00

  • MYC rearrangement and MYC/BCL2 double expression but not cell-of-origin predict prognosis in R-CHOP treated diffuse large B-cell lymphoma.

    abstract:OBJECTIVE:Diffuse large B-cell lymphoma (DLBCL) can be classified as germinal center B cell-like (GCB) or activated B cell-like (ABC)/non-GCB based on cell-of-origin (COO) classification. This study evaluated the prognostic significance of COO classification in 250 patients diagnosed with de novo DLBCL who received R-C...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13384

    authors: Xu J,Liu JL,Medeiros LJ,Huang W,Khoury JD,McDonnell TJ,Tang G,Schlette E,Yin CC,Bueso-Ramos CE,Lin P,Li S

    更新日期:2020-04-01 00:00:00

  • Allogeneic stem cell transplantation in patients with myelofibrosis harboring the MPL mutation.

    abstract:INTRODUCTION:Primary and post-ET/PV myelofibrosis are myeloproliferative neoplasms harboring in most cases driving mutations in JAK2, CALR or MPL, and a variable number of additional mutations in other genes. Molecular analysis represents a powerful tool to guide prognosis and clinical management. Only about 10% of pat...

    journal_title:European journal of haematology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1111/ejh.13318

    authors: Mannina D,Gagelmann N,Badbaran A,Ditschkowski M,Bogdanov R,Robin M,Cassinat B,Heuser M,Shahswar R,Thol F,Beelen D,Kröger N

    更新日期:2019-12-01 00:00:00

  • Impact of central nervous system involvement in AML on outcomes after allotransplant and utility of pretransplant cerebrospinal fluid assessment.

    abstract:OBJECTIVE:The primary objective was to assess the effect of central nervous system involvement in acute myeloid leukemia (CNS-AML) on outcomes after allogeneic hematopoietic stem cell transplant (allo-HCT). The secondary objective was to assess the utility of pretransplant cerebrospinal fluid (CSF) assessment in AML. ...

    journal_title:European journal of haematology

    pub_type: 临床试验,杂志文章

    doi:10.1111/ejh.13314

    authors: Prem S,Atenafu EG,Avena J,Bautista R,Law A,Lam W,Michelis FV,Kim DDH,Viswabandya A,Lipton JH,Mattsson J,Kumar R

    更新日期:2019-11-01 00:00:00

  • Sudden ventricular fibrillation and death during ibrutinib therapy-A case report.

    abstract::Ibrutinib is an oral inhibitor of Bruton tyrosine kinase approved for the treatment of chronic lymphocytic leukaemia, mantle cell lymphoma and refractory Waldenstrom's disease. It increases progression-free survival, overall survival, response rate. The most frequent adverse reactions, are increased risk in of bleedin...

    journal_title:European journal of haematology

    pub_type:

    doi:10.1111/ejh.13290

    authors: Bernardeschi P,Pirrotta MT,Del Rosso A,Fontanelli G,Milandri C

    更新日期:2019-10-01 00:00:00

  • Differences in treatment and monitoring of chronic myeloid leukemia with regard to age, but not sex: Results from a population-based study.

    abstract::There are established guidelines for treatment and monitoring of chronic myeloid leukemia (CML) but little is known about routine care. Data on ICD-10 codes as well as prescribed medications were available for 10.5 million patients in the statutory health insurance system in Bavaria for the years 2010 to 2016. Also, d...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13293

    authors: Lauseker M,Gerlach R,Worseg W,Haferlach T,Tauscher M,Hasford J,Hoffmann VS

    更新日期:2019-10-01 00:00:00

  • Bone marrow WT1 levels in patients with myeloid neoplasms treated with 5-azacytidine: Identification of responding patients.

    abstract:INTRODUCTION:Increased levels of Wilms' tumor (WT1) mRNA have been used to establish risk categories in patients with acute myeloid leukemia (AML). Raised values of WT1 have been associated with progression in myelodysplastic syndrome (MDS). METHODS:We retrospectively analyzed the available bone marrow (BM) samples fr...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13275

    authors: Santaliestra M,Garrido A,Carricondo M,Bussaglia E,Pratcorona M,Blanco ML,Gich I,Hoyos M,Esquirol A,García-Cadenas I,Brunet S,Martino R,Sierra J,Nomdedéu JF

    更新日期:2019-09-01 00:00:00

  • FDA's and EMA's approval of brentuximab vedotin for advanced Hodgkin lymphoma: Another player in the town?

    abstract::ECHELON-1 study is a randomized open-labeled controlled trial investigating whether addition of brentuximab vedotin to chemotherapy offers benefit over the standard chemotherapy regimen in advanced Hodgkin lymphoma. After a median follow-up of 24.6 months, it has met its primary endpoint the reduction of modified prog...

    journal_title:European journal of haematology

    pub_type: 杂志文章,评审

    doi:10.1111/ejh.13269

    authors: Milunović V,Mišura Jakobac K,Kursar M,Mandac Rogulj I,Ostojić Kolonić S

    更新日期:2019-09-01 00:00:00

  • Survival in adult acute lymphoblastic leukaemia (ALL): A report from the Swedish ALL Registry.

    abstract:OBJECTIVES:As new, effective therapies emerge for acute lymphoblastic leukaemia (ALL), the results of clinical trials need to relate to standard of care. METHODS:We used the population-based Swedish ALL Registry to evaluate characteristics, treatment and long-term outcome in 933 patients with diagnosis between 1997 an...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13247

    authors: Lennmyr E,Karlsson K,Ahlberg L,Garelius H,Hulegårdh E,Izarra AS,Joelsson J,Kozlowski P,Moicean A,Tomaszewska-Toporska B,Lübking A,Hallböök H,Swedish Adult Acute Lymphoblastic Leukaemia Group (SVALL).

    更新日期:2019-08-01 00:00:00

  • Direct oral anticoagulants for atrial fibrillation in patients with congenital factor VII deficiency.

    abstract::The management of anticoagulant therapy (OAT) in patients with factor VII (FVII) deficiency is a very challenging clinical issue, as warfarin further reduces FVII levels, thus potentially increasing bleeding risk. On the other hand, the International Normalized Ratio test is misleading in such patients, as they do not...

    journal_title:European journal of haematology

    pub_type: 杂志文章,meta分析

    doi:10.1111/ejh.13246

    authors: Arletti L,Coluccio V,Romagnoli E,Luppi M,Marietta M

    更新日期:2019-07-01 00:00:00

  • Factors predicting early mortality after new diagnosis of myelodysplastic syndrome: A population-based study.

    abstract:OBJECTIVE:Little prospective data regarding factors determining patient outcomes in myelodysplastic syndromes (MDS) are available. To establish features of early mortality in MDS, we compare characteristics of patients dying within 1 year of diagnosis with those surviving longer. METHODS:We prospectively enrolled adul...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13243

    authors: Jacobsen AM,Poynter JN,Richardson MR,Nguyen PL,Hirsch B,Cioc A,Roesler MA,Warlick ED

    更新日期:2019-07-01 00:00:00

  • A new exon 12 mutation in the EPAS1 gene possibly associated with erythrocytosis.

    abstract::In secondary erythrocytosis, the elevated red cell count is powered by factors outside the erythroid compartment, for instance by raised erythropoietin (EPO) synthesis based on congenital defects of the oxygen-sensing pathway. The principal transcriptional regulator of EPO synthesis is endothelial PAS domain-containin...

    journal_title:European journal of haematology

    pub_type:

    doi:10.1111/ejh.13241

    authors: Schelker RC,Herr W,Grassinger J

    更新日期:2019-07-01 00:00:00

  • Autoimmune hemolytic anemia associated with the use of immune checkpoint inhibitors for cancer: 68 cases from the Food and Drug Administration database and review.

    abstract:BACKGROUND:Immune checkpoint inhibitors (CPI) are widely used in modern oncology and have improved the prognosis of lung cancer, malignant melanoma, and other malignancies. Unlike cytotoxic chemotherapy, drugs such as nivolumab, pembrolizumab, and ipilimumab are associated with immune-related adverse effects. We recent...

    journal_title:European journal of haematology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1111/ejh.13187

    authors: Tanios GE,Doley PB,Munker R

    更新日期:2019-02-01 00:00:00

  • Inherited or acquired modifiers of iron status may dramatically affect the phenotype in dehydrated hereditary stomatocytosis.

    abstract::Severe iron overload is frequent in dehydrated hereditary stomatocytosis (DHSt) despite well-compensated hemolysis and no or little transfusion requirement. We investigated 4 patients with proven DHSt, in whom the degree of hemolysis was closely related to iron status. Genetic modifiers increasing iron stores (HFE:pCy...

    journal_title:European journal of haematology

    pub_type:

    doi:10.1111/ejh.13135

    authors: Orvain C,Da Costa L,Van Wijk R,Pissard S,Picard V,Mansour-Hendili L,Cunat S,Giansily-Blaizot M,Cartron G,Schved JF,Aguilar-Martinez P

    更新日期:2018-10-01 00:00:00

  • Quantifying immature platelets as markers of increased platelet production after coronary artery bypass grafting surgery.

    abstract:OBJECTIVES:An increased rate of platelet production is a possible cause of reduced antithrombotic response to once-daily aspirin. Markers of immature platelets (IPs), such as immature platelet count (IPC), immature platelet fraction (IPF), and mean platelet volume (MPV) might be useful for identifying patients who have...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13109

    authors: Xu K,Chan NC,Hirsh J,Ginsberg JS,Bhagirath V,Kruger P,Dale B,Crowther M,Whitlock RP,Li C,Eikelboom JW

    更新日期:2018-09-01 00:00:00

  • Optimising management of deferasirox therapy for patients with transfusion-dependent thalassaemia and lower-risk myelodysplastic syndromes.

    abstract::Effective iron chelation therapy is an important part of treatment in patients with transfusion-dependent thalassaemia and lower-risk myelodysplastic syndromes (MDS). Key strategies for optimising iron chelation therapy include ensuring good adherence and preventing and managing adverse events (AEs). Good adherence to...

    journal_title:European journal of haematology

    pub_type: 杂志文章,评审

    doi:10.1111/ejh.13111

    authors: Kattamis A,Aydinok Y,Taher A

    更新日期:2018-09-01 00:00:00

  • Clinical results according to age in patients with chronic myeloid leukemia receiving imatinib frontline: The younger, the later, the worse?

    abstract:OBJECTIVES:To evaluate differences in clinical results according to age among patients with chronic myeloid leukemia (CML). METHODS:207 consecutive CML patients treated with imatinib frontline were revised, dividing them in young adults (>20 < 45 years) (YA), middle-aged adults (≥45 < 65 years) (MA) and elderly (≥65 y...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13110

    authors: Latagliata R,Breccia M,Carmosino I,Cesini L,De Benedittis D,Mohamed S,Vozella F,Molica M,Campanelli M,De Luca ML,Colafigli G,Quattrocchi L,Loglisci MG,Massaro F,Canichella M,Diverio D,Mancini M,Alimena G,Foà R

    更新日期:2018-06-13 00:00:00

  • Impact of hemophilia B on quality of life in affected men, women, and caregivers-Assessment of patient-reported outcomes in the B-HERO-S study.

    abstract:INTRODUCTION:Health-related quality of life (HRQoL) is impaired in patients with hemophilia; however, the impact in mild/moderate hemophilia B and affected women is not well characterized. OBJECTIVE:To evaluate factors that affect HRQoL in adults with hemophilia B and caregivers of affected children. METHODS:US adult...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13055

    authors: Buckner TW,Witkop M,Guelcher C,Sidonio R,Kessler CM,Clark DB,Owens W,Frick N,Iyer NN,Cooper DL

    更新日期:2018-06-01 00:00:00

  • PlGF and sFlt-1 levels in patients with non-transfusion-dependent thalassemia: Correlations with markers of iron burden and endothelial dysfunction.

    abstract:BACKGROUND:Levels of the angiogenic cytokines placental growth factor (PlGF) and soluble Fms-like tyrosine kinase-1 (sFlt-1) and the angiogenic balance, expressed by sFlt-1/PlGF ratio, are perturbed in sickle-cell disease and iron overload, but they have not been evaluated in non-transfusion-dependent thalassemia (NTDT...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13061

    authors: Kelaidi C,Kattamis A,Apostolakou F,Poziopoulos C,Lazaropoulou C,Delaporta P,Kanavaki I,Papassotiriou I

    更新日期:2018-06-01 00:00:00

  • Clinicopathological characteristics of de novo and secondary myeloid sarcoma: A monocentric retrospective study.

    abstract:OBJECTIVE:Diagnosing myeloid sarcoma remains challenging, and we aimed to provide clinicopathological features to facilitate diagnosis. METHOD:Clinicopathological data from 41 patients with de novo and 31 with secondary myeloid sarcoma were reviewed. RESULTS:Most de novo cases presented with isolated myeloid sarcoma ...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13056

    authors: Claerhout H,Van Aelst S,Melis C,Tousseyn T,Gheysens O,Vandenberghe P,Dierickx D,Boeckx N

    更新日期:2018-06-01 00:00:00

  • Two novel unstable hemoglobin variants due to in-frame deletions of key amino acids in the β-globin chain.

    abstract::Hemoglobinopathies are the most common autosomal recessive disorders and are mostly inherited in a recessive manner. However, certain mutations can affect the globin chain stability, leading to dominant forms of thalassemia. The aim of this work was the molecular and structural characterization of two heterozygous in-...

    journal_title:European journal of haematology

    pub_type: 杂志文章

    doi:10.1111/ejh.13029

    authors: Scheps KG,Hasenahuer MA,Parisi G,Targovnik HM,García E,Veber ES,Crisp R,Elena G,Varela V,Fornasari MS

    更新日期:2018-06-01 00:00:00

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