abstract：RESEARCH QUESTION:Endoplasmic reticulum stress (ERS) is caused by the accumulation of the misfolded or unfolded proteins in the endoplasmic reticulum and induces the unfolded protein response (UPR). Peritoneal fluid is important in the pathogenesis of endometriosis. In this study, the role of UPR associated with ERS in...

journal_title：Reproductive biomedicine online

authors： Ekiz-Yilmaz T,Isildar B,Gezer A,Kankaya D,Cansiz-Ersoz C,Kayisli UA,Guzel E

更新日期：2021-01-01 00:00:00

abstract：RESEARCH QUESTION:Are obstetric and perinatal complications associated with morphokinetic parameters of embryo development? DESIGN:This proof-of-concept pilot study included a retrospective analysis of embryo morphokinetic parameters of 85 live births following day 5 single blastocyst transfer. Kinetic variables inclu...

journal_title：Reproductive biomedicine online

authors： Doron-Lalehzari A,Wainstock T,Szaingurten-Solodkin I,Richter D,Zeadna A,Harlev A,Lunenfeld E,Levitas E,Har-Vardi I

更新日期：2021-01-01 00:00:00

abstract：RESEARCH QUESTION:What ethical implications, issues and concerns play a role in conducting follow-up studies of children born after assisted reproductive technologies (ART)? DESIGN:Literature study and relevant experiences of academic medical centres in Brussels, Belgium, and Maastricht, the Netherlands were used to i...

journal_title：Reproductive biomedicine online

authors： Jans V,Dondorp W,Bonduelle M,de Die C,Mertes H,Pennings G,de Wert G

更新日期：2020-12-01 00:00:00

abstract：RESEARCH QUESTION:Fat accumulation is present in most post-menopausal women, but the underlying mechanism remains unclear. Aquaporin 7 (AQP7) is the most important glycerol channel facilitating glycerol efflux in adipocytes. High circulating FSH in post-menopausal women may play an independent role in regulation of the...

journal_title：Reproductive biomedicine online

authors： Chen L,Chen H,Liu X,Li J,Gao Q,Shi S,Wang T,Ye X,Lu Y,Zhang D,Sheng J,Jin L,Huang H

更新日期：2020-12-01 00:00:00

abstract：RESEARCH QUESTION:To assess whether the incidence of placental disorders of pregnancy decreases with increasing parity in repeat IVF pregnancies, in the same way as natural pregnancies. DESIGN:This was a retrospective cohort of deliveries between November 2008 and January 2020, in a single university-affiliated medica...

journal_title：Reproductive biomedicine online

authors： Ganer Herman H,Mizrachi Y,Farhadian Y,Shevach Alon A,Gluck O,Bar J,Kovo M,Raziel A

更新日期：2020-11-29 00:00:00

abstract：:Oocyte vitrification is an attractive and efficient option in the long-term management of endometriosis patients. Which women would benefit from banked oocytes when pregnancy is attempted, and whether oocyte vitrification should be carried out before or after the surgical management of endometriosis, is still debated....

journal_title：Reproductive biomedicine online

authors： Pluchino N,Roman H

更新日期：2020-11-01 00:00:00

abstract：RESEARCH QUESTION:Does the time interval between the last gonadotrophin-releasing hormone (GnRH) antagonist dose and the GnRH agonist trigger affect the efficacy of the trigger in IVF treatments? DESIGN:This retrospective cohort study involved 53 normogonadotrophic patients undergoing GnRH antagonist-based IVF cycles,...

journal_title：Reproductive biomedicine online

authors： Horowitz E,Mizrachi Y,Farhi J,Raziel A,Weissman A

更新日期：2020-11-01 00:00:00

abstract：RESEARCH QUESTION:Are triglyceride fatty acids in the follicular fluid associated with either follicular fluid phospholipid fatty acids or IVF outcomes and, if so, how are they associated? DESIGN:In a prospective cross-sectional study, 70 women undergoing intracytoplasmic sperm injection were recruited. Follicular flu...

journal_title：Reproductive biomedicine online

authors： Zarezadeh R,Nouri M,Hamdi K,Shaaker M,Mehdizadeh A,Darabia M

更新日期：2020-10-04 00:00:00

abstract：RESEARCH QUESTION:Does the use of preimplantation genetic testing for aneuploidies (PGT-A) improve outcomes in couples with severe male factor infertility (SMFI)? DESIGN:This retrospective cohort study included SMFI cases that underwent blastocyst transfer with/without PGT-A. Inclusion criteria were SMFI (azoospermia ...

journal_title：Reproductive biomedicine online

authors： Asoglu MR,Celik C,Serefoglu EC,Findikli N,Bahceci M

更新日期：2020-10-01 00:00:00

abstract：RESEARCH QUESTION:Does 3-months of gonadotrophin releasing hormone agonist (GnRHa) treatment before IVF improve clinical pregnancy rate in infertile patients with endometriosis? DESIGN:Single-blind, placebo-controlled clinical trial of 200 infertile women with endometriosis assigned to use GnRHa (study group) or place...

journal_title：Reproductive biomedicine online

authors： Rodríguez-Tárrega E,Monzo AM,Quiroga R,Polo-Sánchez P,Fernández-Colom P,Monterde-Estrada M,Novella-Maestre E,Pellicer A

更新日期：2020-10-01 00:00:00

abstract：RESEARCH QUESTION:Do uterine size parameters measured by baseline transvaginal ultrasound predict live birth after single embryo transfer (SET) of a high-quality blastocyst? DESIGN:Retrospective cohort study including women undergoing their first SET between August 2010 and March 2014 at a large university hospital re...

journal_title：Reproductive biomedicine online

authors： Steiner N,Ates S,Shaulov T,Tannus S,Dahan MH

更新日期：2020-10-01 00:00:00

abstract：RESEARCH QUESTION:Does anogenital distance (AGD) differ in newborn infants conceived through assisted reproduction technology (ART) compared with those conceived naturally? DESIGN:This case-control study looked at anthropometric and anogenital measurements in 247 male and 200 female newborns born after ART (n = 121) o...

journal_title：Reproductive biomedicine online

authors： Ercin S,Ertas S,Dundar O,Oktem O,Yakin K

更新日期：2020-09-01 00:00:00

abstract：:The advent of vitrification has transformed the therapeutic landscape in assisted reproductive technology. Clear evidence for this is provided by the dramatic rise in the number of frozen embryo transfer (FET) cycles being carried out annually. In this review, we examine the reasons that underlie this trend and the cu...

journal_title：Reproductive biomedicine online

authors： Ahuja KK,Macklon N

更新日期：2020-08-01 00:00:00

abstract：RESEARCH QUESTION:Does obesity affect endometrial gene expression in women with endometriosis, specifically women with stage I disease? DESIGN:Differential gene expression analysis was conducted on endometrium from women with and without endometriosis (n = 169). Women were diagnosed after surgical visualization and st...

journal_title：Reproductive biomedicine online

authors： Holdsworth-Carson SJ,Chung J,Sloggett C,Mortlock S,Fung JN,Montgomery GW,Dior UP,Healey M,Rogers PA,Girling JE

更新日期：2020-07-01 00:00:00

abstract：RESEARCH QUESTION:How many spermatozoa and slides need to be counted to make a reliable assessment of sperm vitality? Currently, various authorities recommend assessing human sperm vitality on counts of at least 200 cells, but on one or two slides. DESIGN:This was an observational study on duplicate eosin-nigrosin sta...

journal_title：Reproductive biomedicine online

authors： Mortimer D

更新日期：2020-06-01 00:00:00

abstract：:Many clinics offer routine genetic testing of pregnancy loss tissue. This review presents a comprehensive literature search and meta-analysis on chromosomal abnormality rates of pregnancy loss tissue from women with a single or recurrent pregnancy loss. A total of 55 studies published since 2000 were included, analyse...

journal_title：Reproductive biomedicine online

authors： Smits MAJ,van Maarle M,Hamer G,Mastenbroek S,Goddijn M,van Wely M

更新日期：2020-06-01 00:00:00

abstract：RESEARCH QUESTION:What are the optimal values of maternal age and body mass index (BMI), paternal age and BMI, number of oocytes retrieved, and serum AMH concentrations for cumulative live birth rate (CLBR) in IVF and embryo transfer (IVF-ET)? DESIGN:This retrospective cohort study included 9494 women who underwent th...

journal_title：Reproductive biomedicine online

authors： Hu KL,Liu FT,Xu H,Li R,Qiao J

更新日期：2020-05-01 00:00:00

abstract：RESEARCH QUESTION:Multiple sclerosis is predominant in women during the childbearing years and, in case of problems with conceiving naturally, assisted reproductive technology (ART) becomes relevant. The efficacy of ART treatment in women with multiple sclerosis has not previously been studied. Our aim was to examine t...

journal_title：Reproductive biomedicine online

authors： Jølving LR,Larsen MD,Fedder J,Nørgård BM

更新日期：2020-05-01 00:00:00

abstract：RESEARCH QUESTION:When and how does the gradual transition of the endocrine control of early pregnancy from the corpus luteum to the placenta, termed luteoplacental shift, take place? DESIGN:Prospective analysis of serum progesterone levels in pregnancies (n = 88) resulting from programmed frozen-thawed embryo transfe...

journal_title：Reproductive biomedicine online

authors： Neumann K,Depenbusch M,Schultze-Mosgau A,Griesinger G

更新日期：2020-05-01 00:00:00

abstract：RESEARCH QUESTION:To compare stimulated cycle (STC) versus modified natural cycle (MNC) for endometrial preparation prior to frozen embryo transfer (FET) in terms of convenience and efficacy. DESIGN:Prospective, open-label, randomized controlled study including 119 patients aged 20-38 years, undergoing intra-conjugal ...

journal_title：Reproductive biomedicine online

authors： Labrosse J,Lobersztajn A,Pietin-Vialle C,Villette C,Dessapt AL,Jung C,Brussieux M,Bry-Gauillard H,Pasquier M,Massin N

更新日期：2020-04-01 00:00:00

abstract：RESEARCH QUESTION:What is the effect of quercetin and indole-3-carbinol (I3C) on extracellular matrix expression, cell migration and proliferation in human myometrial and uterine leiomyoma cells. DESIGN:Myometrial and leiomyoma cells were treated with quercetin or I3C at different concentrations (10 µg/ml; 50 µg/ml; 1...

journal_title：Reproductive biomedicine online

authors： Greco S,Islam MS,Zannotti A,Delli Carpini G,Giannubilo SR,Ciavattini A,Petraglia F,Ciarmela P

更新日期：2020-04-01 00:00:00

abstract：RESEARCH QUESTION:What is the prevalence of triplet and quadruplet pregnancies after single embryo transfer (SET) in Japan. DESIGN:A retrospective observational study was conducted on 274,605 pregnancies after 937,848 SET cycles in registered assisted reproductive technology (ART) data from the Japanese ART national r...

journal_title：Reproductive biomedicine online

authors： Yamashita S,Ikemoto Y,Ochiai A,Yamada S,Kato K,Ohno M,Segawa T,Nakaoka Y,Toya M,Kawachiya S,Sato Y,Takahashi T,Takeuchi S,Nomiyama M,Tabata C,Fujiwara T,Okamoto S,Kawamura T,Kawagoe J,Yamada M,Sato Y,Marumo G,

更新日期：2020-03-01 00:00:00

abstract：RESEARCH QUESTION:Does fetal reduction of triplet pregnancies to singleton result in superior obstetric and neonatal outcomes compared with triplets reduced to twins? DESIGN:A historical cohort study including 285 trichorionic and dichorionic triplet pregnancies that underwent abdominal fetal reduction at 11-14 weeks ...

journal_title：Reproductive biomedicine online

authors： Zemet R,Haas J,Bart Y,Barzilay E,Zloto K,Argaman N,Schwartz N,Weisz B,Yinon Y,Mazaki-Tovi S,Lipitz S

更新日期：2020-03-01 00:00:00

abstract：RESEARCH QUESTION:Can single-nucleotide polymorphisms (SNP) of genes related to progesterone synthesis predict the risk of premature serum progesterone elevation in women undergoing gonadotrophin-releasing hormone agonist protocols for ovarian stimulation? DESIGN:A total of 765 women were divided into high progesteron...

journal_title：Reproductive biomedicine online

authors： Cao P,Miao B,Xu Y,Fan Q,Zhang Q,Zhang G,Zhou C,Xu Y

更新日期：2020-03-01 00:00:00

abstract：RESEARCH QUESTION:Which cryopreservation method better protects reproductive potential: the cryopreservation of a testicular cell suspension (TCS) or the cryopreservation of testicular tissue (TET)? DESIGN:Two cryopreservation strategies for spermatogonial stem cells (SSCs) were compared in a mouse model: cryopreserva...

journal_title：Reproductive biomedicine online

authors： Onofre J,Kadam P,Baert Y,Goossens E

更新日期：2020-02-01 00:00:00

abstract：RESEARCH QUESTION:There is some controversy regarding the impact of ovarian stimulation on immune cells in women undergoing IVF. The study's aim was to determine whether ovarian stimulation affected immune uterine cells in healthy women undergoing IVF. DESIGN:This prospective cohort study included 28 patients undergoi...

journal_title：Reproductive biomedicine online

authors： Alecsandru D,Pacheco A,Guerrero-Mayo A,Fabris A,Aparicio P,Barrio A,Pellicer A,Garcia-Velasco JA

更新日期：2020-01-01 00:00:00

abstract：RESEARCH QUESTION:What is the cost-effectiveness of gonadotrophins compared with clomiphene citrate in couples with unexplained subfertility undergoing intrauterine insemination (IUI) with ovarian stimulation under strict cancellation criteria? DESIGN:A cost-effectiveness analysis alongside a randomized controlled tri...

journal_title：Reproductive biomedicine online

authors： Danhof NA,van Wely M,Repping S,van der Ham DP,Klijn N,Janssen ICAH,Rijn-van Weert JM,Twisk M,Traas MAF,Pelinck MJ,Perquin DAM,Boks DES,Sluijmer A,Mol BWJ,van der Veen F,Mochtar MH,Amsterdam SUPER Study Group.

更新日期：2020-01-01 00:00:00

abstract：RESEARCH QUESTION:Does using an objective time-lapse imaging algorithm (TLIA) after IVF relate to conventional morphological assessment of human blastocysts as a prognosticator for live birth? DESIGN:Prospective use of a TLIA to select embryos in multicentre IVF clinics all using the same strictly controlled laborator...

journal_title：Reproductive biomedicine online

authors： Fishel S,Campbell A,Foad F,Davies L,Best L,Davis N,Smith R,Duffy S,Wheat S,Montgomery S,Wachter A,Beccles A

更新日期：2020-01-01 00:00:00

abstract：RESEARCH QUESTION:Does the quality of transferred embryos have an impact on the rate of congenital malformations in IVF/intracytoplasmic sperm injection (ICSI)-conceived babies? DESIGN:Retrospective cohort study involving 6637 pregnancies of ≥20 weeks' gestation from women undergoing embryo transfer with a single Day ...

journal_title：Reproductive biomedicine online

authors： Abel K,Healey M,Finch S,Osianlis T,Vollenhoven B

更新日期：2019-12-01 00:00:00

abstract：RESEARCH QUESTION:Can serum oestradiol concentrations on the day of progesterone initiation predict live birth rates in single, autologous vitrified-warmed blastocyst transfers following artificial endometrial preparation? DESIGN:This retrospective study included the first transfers of 468 patients with unexplained or...

journal_title：Reproductive biomedicine online

authors： Celik C,Asoglu MR,Karakis LS,Findikli N,Gultomruk M,Cavkaytar S,Bahceci M

更新日期：2019-12-01 00:00:00

abstract：RESEARCH QUESTION:The study aimed to evaluate the associations of endocrine and ultrasound characteristics with metabolic syndrome in women with polycystic ovary syndrome (PCOS), and whether these associations were modified by body mass index (BMI). DESIGN:The study was a secondary analysis of baseline data from a ran...

journal_title：Reproductive biomedicine online

authors： Li J,Wu Q,Wang CC,Wang R,Ng EHY,Liu JP,Mol BWJ,Wu XK,Li WT,PCOSAct Study Group.

更新日期：2019-11-01 00:00:00

abstract：RESEARCH QUESTION:Does ovarian stimulation for oocyte vitrification affect disease-free survival and overall survival rates in women with early breast cancer? DESIGN:This cohort study included 259 patients with early breast cancer; 148 patients underwent ovarian stimulation, whereas 111 patients did not. Patients were...

journal_title：Reproductive biomedicine online

authors： Muñoz E,Domingo J,De Castro G,Lorenzo I,García-Velasco JA,Bellver J,Pellicer A,Garrido N

更新日期：2019-11-01 00:00:00

abstract：RESEARCH QUESTION:What is the influence of the Caesarean section-pregnancy interval (CSPI) on the risk of uterine rupture, and what are the repercussions on IVF pregnancy rates of prolonging it? STUDY DESIGN:Systematic searches were performed using PubMed MEDLINE to identify studies published up until July 2017 for ar...

journal_title：Reproductive biomedicine online

authors： Matorras R,Berreteaga L,Laínz L,Exposito A,Martínez L

更新日期：2019-11-01 00:00:00

abstract：RESEARCH QUESTION:To determine whether there is a risk of localized Zika virus (ZIKV) infection in the upper genital tract, specifically the oocytes, follicular fluids and endometrium, in exposed and/or recently infected reproductive-age women. ZIKV is an Aedes mosquito-borne Flavivirus that can lead to birth defects a...

journal_title：Reproductive biomedicine online

authors： Prisant N,Joguet G,Herrmann-Stock C,Moriniere C,Pavili L,Lurel S,Bujan L

更新日期：2019-10-01 00:00:00

abstract：RESEARCH QUESTION:Is a mixture of preconception serum lipids and lipophilic micronutrients associated with clinical pregnancy and live births? DESIGN:In this prospective cohort study, blood serum was collected on the day of oocyte retrieval for 180 women undergoing IVF at an academic reproductive health centre. Concen...

journal_title：Reproductive biomedicine online

authors： Jamro EL,Bloom MS,Browne RW,Kim K,Greenwood EA,Fujimoto VY

更新日期：2019-10-01 00:00:00

abstract：RESEARCH QUESTION:A close association between Kisspeptin-1 (KISS-1) and reproductive physiology has been reported, but the results on circulatory KISS-1 are ambiguous in patients with polycystic ovary syndrome (PCOS). A systematic review and meta-analysis were conducted to evaluate the association between KISS-1 and PC...

journal_title：Reproductive biomedicine online

authors： Varikasuvu SR,Prasad VS,Vamshika VC,Satyanarayana MV,Panga JR

更新日期：2019-10-01 00:00:00

abstract：RESEARCH QUESTION:Which factors are associated with reproductive outcomes among infertile women undergoing myomectomy for intramural fibroids? DESIGN:This was a historical cohort study including 127 infertile women who underwent myomectomy due to intramural fibroids as part of fertility enhancement treatment at a sing...

journal_title：Reproductive biomedicine online

authors： Lebovitz O,Orvieto R,James KE,Styer AK,Brown DN

更新日期：2019-09-01 00:00:00

abstract：RESEARCH QUESTION:Does artificial oocyte activation improve clinical outcomes for patients at risk of intracytoplasmic sperm injection (ICSI) fertilization failure? DESIGN:In this study, sibling oocytes from patients with previous ICSI failure or severe teratozoospermia were divided equally into two groups, half for a...

journal_title：Reproductive biomedicine online

authors： Li J,Zheng X,Lian Y,Li M,Lin S,Zhuang X,Chen L,Liu P,Qiao J

更新日期：2019-08-01 00:00:00

abstract：RESEARCH QUESTION:Does extending the follow-up after misoprostol treatment for early pregnancy loss increase the success rate? DESIGN:Patients who had experienced early pregnancy loss (<12 weeks) and were treated with misoprostol in a single university-affiliated medical centre were prospectively followed before and a...

journal_title：Reproductive biomedicine online

authors： Mizrachi Y,Tamayev L,Shemer O,Kleiner I,Bar J,Sagiv R

更新日期：2019-07-01 00:00:00

abstract：RESEARCH QUESTION:What is the relationship between the vaginal microbiota profile at the time of embryo transfer and live birth rates in women undergoing IVF/intracytoplasmic sperm injection (ICSI) with donated oocytes? DESIGN:One hundred and fifty Caucasian women receiving donated oocytes were prospectively included ...

journal_title：Reproductive biomedicine online

authors： Vergaro P,Tiscornia G,Barragán M,García D,Rodriguez A,Santaló J,Vassena R

更新日期：2019-06-01 00:00:00