abstract：OBJECTIVE:Accumulating evidence has demonstrated that long non-coding RNAs (lncRNAs) play important regulatory roles in the tumorigenesis and progression of gastric cancer (GC). The aim of this study was to construct the prognostic predictive model of lncRNAs signature and improve the survival prediction of GC. PATIEN...

journal_title：Gastroenterologia y hepatologia

authors： Zong Z,Li H,Yu ZM,Tang FX,Zhu XJ,Tian HK,Zhou TC,Wang H

更新日期：2020-12-01 00:00:00

abstract：INTRODUCTION:Faecal calprotectin is a useful technique for detecting activity in patients with ulcerative colitis. However, there may be high levels due to factors other than the activity of ulcerative colitis. Our aim was to analyse possible false positive results of calprotectin for the activity of ulcerative colitis...

journal_title：Gastroenterologia y hepatologia

authors： Bermejo F,Algaba A,Bonillo D,Jiménez L,Guardiola-Arévalo A,Pacheco M,Castaño Á,Guerra I

更新日期：2020-02-01 00:00:00

abstract：:The rate of non-adherence to medical treatment in inflammatory bowel disease (IBD) is around 50%, with the consequent negative impact on treatment results, morbidity and cost. OBJECTIVES:To determine through an online survey among gastroenterologists with special dedication to IBD, their knowledge about the adherence...

journal_title：Gastroenterologia y hepatologia

authors： Alonso-Abreu I,Alarcón-Fernández O,Carrillo-Palau M,Ramos-López L,Gisbert JP,Chaparro M,Nos P,Jiménez A,Quintero-Carrión E,en representación de GETECCU.

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:Bibliometric search of citation classics can function as a tool to identify extraordinary landmark articles and advanced research studies. We aimed to examine and characterize the 100 most-cited published articles in the field of hepatology. PATIENTS AND METHODS:A comprehensive list of the 100 most-cited art...

journal_title：Gastroenterologia y hepatologia

authors： Yu Q,Tan S,Ren Y,He M,Fu X,Peng Y,Tang X

更新日期：2020-01-01 00:00:00

abstract：:Eradication of the hepatitis C virus (HCV) with interferon-free therapies (DAAs) has modified the course of the disease, as the rate of patients with compensated cirrhosis who achieve a sustained virological response exceeds 95%. However, the impact on development of hepatocellular carcinoma (HCC) is currently in disp...

journal_title：Gastroenterologia y hepatologia

authors： Hernáez-Alsina T,Caballol-Oliva B,Díaz-González Á,Guedes-Leal C,Reig M

更新日期：2019-10-01 00:00:00

abstract：:TThe incorporation of direct-acting antiviral agents to the treatment of chronic hepatitis C infection has simplified diagnosis and follow-up, allowing optimisation of health resources (consultations and tests) dedicated to the management of the disease. The aim of this study was to estimate the economic impact of thi...

journal_title：Gastroenterologia y hepatologia

authors： Turnes J,García F,Diago M,Andrade RJ,Díaz P,Rubio-Rodríguez D,Rubio-Terrés C

更新日期：2019-09-01 00:00:00

abstract：:Faecal immunochemical tests for haemoglobin (FIT), as an adjunct to clinical information, assist in the triage of patients presenting in primary care with lower abdominal symptoms. Controversy remains regarding whether and which qualitative and quantitative FIT can be used, which groups of patients would benefit most ...

journal_title：Gastroenterologia y hepatologia

authors： Fraser CG

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:The socioeconomic burden of irritable bowel syndrome with constipation (IBS-C) has never been formally assessed in Spain. PATIENTS AND METHODS:This 12-month (6-month retrospective and prospective periods) observational, multicentre study assessed the burden of moderate-to-severe IBS-C in Spain. Patients w...

journal_title：Gastroenterologia y hepatologia

authors： Mearin F,Caballero AM,Serra J,Brotons C,Tantiñà A,Fort E,Martínez-Cerezo FJ,Perelló A,Sánchez-Antolín G,Rey E,Angós Musgo R,Berdier R,Gómez-Rodríguez B,Clavé P,García-Alonso M,Torán-Monserrat P,Tack J

更新日期：2019-03-01 00:00:00

abstract：:The development of high-definition endoscopes with optical zoom, along with the use of the digital chromoendoscopy and staining, has given endoscopists the possibility to study the microanatomy of the gastrointestinal mucosa in vivo. The recognition of the changes in the microstructure of the surface and microvascular...

journal_title：Gastroenterologia y hepatologia

authors： Uchima H,Yao K

更新日期：2019-02-01 00:00:00

abstract：INTRODUCTION:To assess the efficacy and safety of gastric peroral endoscopic myotomy for the treatment of gastroparesis. METHODS:PubMed, Embase, Cochrane Library and Web of Science databases were searched from their earliest records to May 2018. The evaluation of clinical efficacy and safety was based on gastric empty...

journal_title：Gastroenterologia y hepatologia

authors： Zhang H,Zhang J,Jiang A,Ni H

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIM:Treatment for portal vein thrombosis (PVT) is not well established. Nevertheless, anticoagulation therapy can seemingly be used as first-line therapy. However, there are limited data on the role of this treatment in patients with PVT and cirrhosis. We sought to assess the safety and efficacy of antic...

journal_title：Gastroenterologia y hepatologia

authors： Artaza T,Lopes M,Romero M,Gómez AZ,de la Cruz G,Sánchez JJ,González C,Gómez R

更新日期：2018-12-01 00:00:00

abstract：:Video capsule endoscopy (VCE) is a reliable noninvasive method for examination of small-bowel mucosa. However, it has some limitations. The aim of this article was to review the approach in patients with negative VCE. It is clear that a negative VCE should be interpreted based on the indication. In suspected small bow...

journal_title：Gastroenterologia y hepatologia

authors： Sousa M,Pinho R,Rodrigues A,Carvalho J

更新日期：2018-12-01 00:00:00

abstract：INTRODUCTION:Thiopurine therapy can be optimised by determining the concentration of the drug's metabolites. PATIENTS AND METHODS:Retrospective analysis on a prospective database of 31 patients with inflammatory bowel disease who failed therapy with thiopurines. Thiopurine metabolites (6-thioguanine, 6-TGN and 6-methy...

journal_title：Gastroenterologia y hepatologia

authors： Sánchez Rodríguez E,Ríos León R,Mesonero Gismero F,Albillos A,Lopez-Sanroman A

更新日期：2018-12-01 00:00:00

abstract：INTRODUCTION:The eradication of Helicobacter pylori infection represents a clinical challenge. OBJECTIVE:To evaluate the efficacy and safety of quadruple therapy with esomeprazole plus a 3-in-1 capsule containing bismuth subcitrate, metronidazole and tetracycline, plus probiotics in patients diagnosed with H. pylori i...

journal_title：Gastroenterologia y hepatologia

authors： Pérez-Arellano E,Rodriguez-Garcia MI,Galera Rodenas AB,de la Morena-Madrigal E

更新日期：2018-03-01 00:00:00

abstract：:Acute-on-chronic liver failure (ACLF) is a recently defined syndrome characterised by acute decompensation of chronic liver disease, associated with organ failures and high mortality. ACLF is a common condition and may affect up to 30% of patients admitted to hospital for cirrhosis complications. Bacterial infections,...

journal_title：Gastroenterologia y hepatologia

authors： Solé C,Solà E

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Iron deficiency without anaemia (IDWA) is commonly found in outpatients with inflammatory bowel disease (IBD) in an even higher proportion than anaemia. However, its true prevalence and possible impact on health-related quality of life (HRQoL) are unknown. The objectives of this study were: to establish th...

journal_title：Gastroenterologia y hepatologia

authors： González Alayón C,Pedrajas Crespo C,Marín Pedrosa S,Benítez JM,Iglesias Flores E,Salgueiro Rodríguez I,Medina Medina R,García-Sánchez V

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Genotypic distribution and epidemiology of HCV infection in Western Europe countries has changed over the last decades. AIM:To establish the local genotypic profile and characterize the associated demographic variables. MATERIAL AND METHOD:All the genotyping from 1988 to 2015 were considered. Associated de...

journal_title：Gastroenterologia y hepatologia

authors： Acero Fernández D,Ferri Iglesias MJ,Buxó Pujolràs M,López Nuñez C,Serra Matamala I,Queralt Molés X,Aldeguer Manté X

更新日期：2018-01-01 00:00:00

abstract：:Since ancient times the increase of size and hardness sometimes presented by the abdominal structure known as the pancreas has attracted attention. Portal was the first to describe the clinical signs of chronic pancreatitis in 1803. In 1815, Fleischman speculated about the potential role of excessive alcohol consumpti...

journal_title：Gastroenterologia y hepatologia

authors： Navarro S

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To describe the epidemiological, analytical and histological characteristics and clinical course of hepatitis B virus (HBV) carriers with negative HBe antigen. MATERIAL AND METHODS:Observational, retrospective cohort study of HBV carriers with negative HBe antigen (2005-2012), with no other causes of liver d...

journal_title：Gastroenterologia y hepatologia

authors： Guardiola Arévalo A,Gómez Rodríguez R,Romero Gutiérrez M,Gómez Moreno AZ,García Vela A,Sánchez Simón R,Gómez Hernando C,Andrés Esteban EM

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Strong acid inhibition increases cure rates with triple therapy and 14-day are more effective than 7-day treatments. The combination of amoxicillin plus metronidazole at full doses has been shown to overcome metronidazole resistance and to achieve good eradication rates even in patients harboring resistant s...

journal_title：Gastroenterologia y hepatologia

authors： Dacoll C,Sánchez-Delgado J,Balter H,Pazos X,Di Pace M,Sandoya G,Cohen H,Calvet X

更新日期：2017-01-01 00:00:00

abstract：:Helicobacter pylori approximately infect 50% of Spanish population and causes chronic gastritis, peptic ulcer and gastric cancer. Until now, three consensus meetings on H.pylori infection had been performed in Spain (the last in 2012). The changes in the treatment schemes, and the increasing available evidence, have j...

journal_title：Gastroenterologia y hepatologia

authors： Gisbert JP,Molina-Infante J,Amador J,Bermejo F,Bujanda L,Calvet X,Castro-Fernández M,Cuadrado-Lavín A,Elizalde JI,Gene E,Gomollón F,Lanas Á,Martín de Argila C,Mearin F,Montoro M,Pérez-Aisa Á,Pérez-Trallero E,McNicholl A

更新日期：2016-12-01 00:00:00

abstract：INTRODUCTION:Large serrated polyps (SP), proximal SP, SP with dysplasia and the presence of multiple sessile serrated adenomas/polyps (SSA/P), which we refer to as SP with increased risk of metachronous lesions (SPIRML), have been associated with an increased risk of advanced colon lesions on follow-up. It is unclear, ...

journal_title：Gastroenterologia y hepatologia

authors： Urman J,Gomez M,Basterra M,Mercado MD,Montes M,Gómez Dorronsoro M,Garaigorta M,Fraile M,Rubio E,Aisa G,Galbete A

更新日期：2016-11-01 00:00:00

abstract：INTRODUCTION:Variceal upper gastrointestinal bleeding (UGIB) can trigger acute hypoxic hepatitis (AHH). The aim of this study was to analyse the incidence, associated risk factors and mortality of AHH after variceal UGIB. PATIENTS AND METHODS:Retrospective study of cirrhotic patients with variceal UGIB, classified int...

journal_title：Gastroenterologia y hepatologia

authors： Senosiain Lalastra C,Arribas Anta J,Moreira Vicente V,Martínez González J,Maroto Castellanos M,García Sánchez MC,Zaera de la Fuente C,López Durán S,Cañete Ruiz Á,Albillos Martínez A

更新日期：2016-11-01 00:00:00

abstract：:Despite better knowledge of the pathogenesis of severe alcoholic hepatitis (AH), corticosteroids are still the treatment recommended by clinical guidelines, pentoxifylline being the second-line option for non-responders to corticosteriods and for patients with contraindications. Pentoxifylline is a phosphodiesterase i...

journal_title：Gastroenterologia y hepatologia

authors： Caballeria J

更新日期：2016-10-01 00:00:00

abstract：:Inflammatory bowel disease is a chronic disorder of unknown aetiology that results from a pathologic response from both the innate and acquired immune systems, leading to chronic inflammation of the gastrointestinal tract. New drugs have been introduced into the therapeutic armamentarium of inflammatory bowel disease ...

journal_title：Gastroenterologia y hepatologia

authors： Chaparro M

更新日期：2016-09-01 00:00:00

abstract：:Pancreatic cancer continues to have a bleak prognosis. Hardly any therapeutic advances have been made in the last few years and consequently most efforts have focused on preventing its development and on diagnosing precursor lesions. In this regard, the use of statins as a preventive factor and the implementation of s...

journal_title：Gastroenterologia y hepatologia

authors： Lariño Noia J

更新日期：2016-09-01 00:00:00

abstract：INTRODUCTION:Matrix metalloproteinases (MMPs) are overexpressed at different stages of colorectal carcinogenesis and could serve as early surrogate biomarkers of colorectal neoplasia. OBJECTIVE:To assess the utility of plasma MMP2 and MMP9 levels in the detection of advanced colorectal neoplasia and their correlation ...

journal_title：Gastroenterologia y hepatologia

authors： Gimeno-García AZ,Triñanes J,Quintero E,Salido E,Nicolás-Pérez D,Adrián-de-Ganzo Z,Alarcón-Fernández O,Abrante B,Romero R,Carrillo M,Ramos L,Alonso I,Ortega J,Jiménez A

更新日期：2016-08-01 00:00:00

abstract：:Early TIPS is basically a new application of an old concept. This intervention used to be a useful rescue therapy when other interventions failed but has now become a primary intervention in patients with variceal bleeding and risk factors for poor prognosis. This technique has also been proven to control bleeding and...

journal_title：Gastroenterologia y hepatologia

authors： Ruiz-Blard E,Baiges A,Turon F,Hernández-Gea V,García-Pagán JC

更新日期：2016-08-01 00:00:00

abstract：INTRODUCTION:Randomized controlled trials provide the best scientific evidence for the efficacy of biological drugs in inflammatory bowel disease (IBD). However, findings obtained from these trials might not be reproducible in clinical practice. This study aimed to estimate the percentage of patients with IBD treated w...

journal_title：Gastroenterologia y hepatologia

authors： Ginard D,Khorrami S,Pérez-Carazo L,Tavío-Hernández E,López-Sanromán A,García-Alvarado M,Muñoz F,Ibáñez-Samaniego L,Marín-Jiménez I,Guevara J,Casellas F

更新日期：2016-06-01 00:00:00

abstract：INTRODUCTION:Vitamin D (VD) is known to have multiple extra-skeletal health functions. There is emerging interest in exploring the relationship between vitamin D and chronic liver disease (CLD). OBJECTIVES:To determine the prevalence of VD deficiency in patients with CLD in our setting and to assess whether VD supplem...

journal_title：Gastroenterologia y hepatologia

authors： Fernández Fernández N,Linares Torres P,Joáo Matias D,Jorquera Plaza F,Olcoz Goñi JL

更新日期：2016-05-01 00:00:00

abstract：:The present article makes a brief review about dental management of the patients with cirrhosis. It focus on problems related with infections, haemorrhagic events and treatment with drugs of common use in odontology. ...

journal_title：Gastroenterologia y hepatologia

authors： Rodríguez Martínez S,Talaván Serna J,Silvestre FJ

更新日期：2016-03-01 00:00:00

abstract：INTRODUCTION:Triple therapy with telaprevir or boceprevir has proven to be effective in the treatment of chronic hepatitis C with response rates of up to 88%. However, the treatment may be associated with important adverse effects and a high economic impact. OBJECTIVE:To assess the cost-effectiveness and safety of tri...

journal_title：Gastroenterologia y hepatologia

authors： Giménez-Manzorro Á,García-González X,Rodríguez-González CG,Ochoa-Palominos A,Sanjurjo-Sáez M,Clemente-Ricote G

更新日期：2015-12-01 00:00:00

abstract：:Colorectal cancer is the most frequent malignancy in both sexes in Spain. Between 20% and 25% of affected individuals have a family history of the disease, and 5% to 6% have a germ mutation, i.e. the disease develops in the context of a hereditary syndrome. The importance of identifying patients with hereditary syndro...

journal_title：Gastroenterologia y hepatologia

authors： Moreira L

更新日期：2015-09-01 00:00:00

abstract：:Hepatitis B virus (HBV) infection continues to be a major public health problem worldwide. Although treatment indications are well established in clinical practice guidelines, there are some risk groups, such as pregnant women and immunosuppressed patients, who require different and specific management of HBV infectio...

journal_title：Gastroenterologia y hepatologia

authors： Riveiro-Barciela M,Buti M

更新日期：2015-01-01 00:00:00

abstract：:Hepatitis B virus (HBV) reactivation after chemotherapy regimens is a well-known complication. The incidence and risk factors for HBV reactivation remain to be elucidated. We aimed to determine the incidence and risk factors for HBV reactivation in patients receiving rituximab, and the potential role of the cumulative...

journal_title：Gastroenterologia y hepatologia

authors： Gutiérrez García ML,Alonso Lopez S,Martín Rios MD,Sanmartin Fenollera P,Agudo Fernandez S,Fernández Rodriguez CM

更新日期：2015-01-01 00:00:00

abstract：INTRODUCTION:Antiviral drugs for the treatment of hepatitis C virus (HCV) infections have a large number of interactions. The aim of this study was to describe the interactions of telaprevir, boceprevir and sofosbuvir with immunosuppressive drugs in liver transplant recipients. METHODS:A retrospective observational st...

journal_title：Gastroenterologia y hepatologia

authors： Ruiz Ramos J,Romero Hernández I,Marrero Álvarez P,Marqués Miñana MR,Fernández Megía MJ,Poveda Andrés JL

更新日期：2014-12-01 00:00:00

abstract：:Colonoscopies play a vital role in population screening programs, either for initial examinations or as a test carried out after a positive result from a fecal occult blood test or sigmoidoscopy. Colonoscopies, and ancillary techniques such as polipectomies, must comply with basic quality criteria that must be reflect...

journal_title：Gastroenterologia y hepatologia

authors： Bessa Caserras X

更新日期：2014-09-01 00:00:00

abstract：INTRODUCTION:The prevalence of Barrett's esophagus (BE) varies from 0.45% to 2.2% in patients who undergo upper endoscopy and is >12% when the indication is for reflux symptoms. The prevalence has progressively increased in recent years but is unknown in the population of the province of Barcelona. OBJECTIVES:To deter...

journal_title：Gastroenterologia y hepatologia

authors： Rodríguez-D'Jesús A,Gordillo J,Uchima H,Araujo I,Saperas E,Elizalde I,Fernández-Esparrach G

更新日期：2014-08-01 00:00:00

abstract：:Hepatitis B is currently an excellent indication for liver transplantation due to the highly effective strategies of prophylaxis and treatment for recurrent hepatitis B infection. The combined administration of low-dose hepatitis B hyperimmune gamma globulin and a nucleoside/nucleotide analogue with a high genetic bar...

journal_title：Gastroenterologia y hepatologia

authors： Prieto M,García-Eliz M

更新日期：2014-07-01 00:00:00

abstract：:Functional dyspepsia is defined as a group of symptoms, whether related or unrelated to intake, localized in the upper abdomen, that manifest in the form of discomfort or epigastric pain, postprandial fullness and early satiety, in the absence of any demonstrable organic or structural anomaly. The etiopathogenesis and...

journal_title：Gastroenterologia y hepatologia

authors： Sebastián-Domingo JJ

更新日期：2014-04-01 00:00:00