abstract：OBJECTIVE:This study aimed to analyze the clinical and genetic characteristics of Chinese children with congenital hyperinsulinemia (CHI) that is spontaneously relieved. METHODS:The patient group comprised 200 children with CHI that were treated at the Beijing Children's Hospital from January 2006 to December 2018. Th...

journal_title：Endocrine

authors： Xu ZD,Hui PP,Zhang W,Zeng Q,Zhang L,Liu M,Yan J,Wu YJ,Sang YM

更新日期：2021-01-27 00:00:00

abstract：INTRODUCTION:Primary autoimmune hypophysitis (PAHs) is a rare inflammatory disease of the pituitary gland. Although largely investigated, the pathogenesis of PAH is not completely clarified. We aimed to investigate the immune response in PAHs. MATERIAL AND METHODS:Serum anti-pituitary and anti-hypothalamus antibodies ...

journal_title：Endocrine

authors： Chiloiro S,Giampietro A,Angelini F,Arena V,Stigliano E,Tartaglione T,Mattogno PP,D'Alessandris QG,Lauretti L,Pontecorvi A,De Marinis L,Bianchi A

更新日期：2021-01-23 00:00:00

abstract：PURPOSE:The distinction between congenital hypogonadotropic hypogonadism (CHH) and constitutional delay of growth and puberty (CDGP) in patients with delayed puberty is difficult to distinguish, but important for timely treatment. The aim of this study is to perform a systematic review and meta-analysis to determine th...

journal_title：Endocrine

authors： Gao Y,Du Q,Liu L,Liao Z

更新日期：2021-01-19 00:00:00

abstract：PURPOSE:Insulin resistance is an important factor in the pathogenesis of polycystic ovary syndrome (PCOS), which is associated with higher risk of metabolic syndrome (MetS) and cardiovascular complications. Early atherosclerotic lesions may be diagnosed by ultrasonographic parameters: brachial artery flow-mediated dila...

journal_title：Endocrine

authors： Krentowska A,Łebkowska A,Jacewicz-Święcka M,Hryniewicka J,Leśniewska M,Adamska A,Kowalska I

更新日期：2021-01-13 00:00:00

abstract：PURPOSE:Throughout the SARS-CoV2 pandemic, multiple reports show higher percentages of hospitalization, morbidity, and mortality among men than women, indicating that men are more affected by COVID-19. The pathophysiology of this difference is yet not established, but recent studies suggest that sex hormones may influe...

journal_title：Endocrine

authors： Mohamed MS,Moulin TC,Schiöth HB

更新日期：2021-01-01 00:00:00

abstract：:Thioredoxin-interacting protein (TXNIP) is a known important regulatory protein of islet β-cell biology and function, but the detailed mechanism is not clear. Autophagy plays a pivotal role in maintaining cellular homoeostasis. This study aimed to elucidate the influence of TXNIP on the autophagy of β-cell. In this st...

journal_title：Endocrine

authors： Deng W,Li Y,Ren Z,He Q,Jia Y,Liu Y,Zhang W,Gan X,Liu D

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:Angiogenesis has been studied in pituitary neuroendocrine tumours (PitNETs), but the role of the tumour microenvironment (TME) in regulating PitNET angiogenesis remains unknown. We aimed to characterise the role of TME components in determining the angiogenetic PitNET profile, focusing on immune cells and tumou...

journal_title：Endocrine

authors： Marques P,Barry S,Carlsen E,Collier D,Ronaldson A,Dorward N,Grieve J,Mendoza N,Nair R,Muquit S,Grossman AB,Korbonits M

更新日期：2020-12-01 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Endocrine

authors： Poli R,Scatolini M,Grosso E,Maletta F,Gallo M,Liscia D,Nelva A,Cesario F,Forte G,Metovic J,Volante M,Arvat E,Papotti M

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:The aims of this study were to assess the role of an in-house competitive thyroglobulin assay (Tg-c) in the follow-up of metastatic differentiated thyroid carcinoma (DTC) patients who presented underestimated Tg measurements by immunometric assays (Tg-IMA) and to compare the results with IMA and LC-MS/MS Tg met...

journal_title：Endocrine

authors： Guastapaglia L,Kasamatsu TS,Nakabashi CCD,Camacho CP,Maciel RMB,Vieira JGH,Biscolla RPM

更新日期：2020-11-22 00:00:00

abstract：PURPOSE:Anti-Müllerian hormone (AMH) is crucial for folliculogenesis. Prenatal exposure to AMH in mice produces a phenocopy of polycystic ovary syndrome (PCOS) in the adult female offspring. The aim of this study was to determine whether genetic variation in AMH gene contribute to PCOS in women of Chinese ancestry. ME...

journal_title：Endocrine

authors： Qin L,Zhao S,Yang P,Cao Y,Zhang J,Chen ZJ,Dunaif A,Zhao H

更新日期：2020-11-09 00:00:00

abstract：PURPOSE:We aimed to evaluate the performance of structural magnetic resonance imaging (MRI)-based quantitative measurements at extraocular muscle (EOM), orbital fat (OF), and especially lacrimal gland (LG) in predicting response to glucocorticoid (GC) in patients with active and moderate-severe thyroid-associated ophth...

journal_title：Endocrine

authors： Hu H,Xu XQ,Chen L,Chen W,Wu Q,Chen HH,Zhu H,Shi HB,Wu FY

更新日期：2020-11-01 00:00:00

abstract：PURPOSE:Histologic and pTNM classification of differentiated thyroid cancer (DTC) is mandatory to assess risk of relapse, risk of death, and radioactive iodine administration. The impact of an expert central review of external pathology reports has not yet been reported. METHODS:Monocentric retrospective study to eval...

journal_title：Endocrine

authors： Hescot S,Sheikh-Alard H,Kordahi M,Hartl D,Hadoux J,Terroir M,Breuskin I,Baudin E,Scoazec JY,Schlumberger M,Al Ghuzlan A,Leboulleux S

更新日期：2020-10-31 00:00:00

abstract：PURPOSE:To evaluate the serum level of zonulin, which is an intestinal permeability (IP) biomarker, in primary hyperparathyroidism (PHPT) and to investigate the relationship between zonulin, calcium, and parathormone (PTH) levels. METHODS:The study included 34 healthy control (HC) and 39 patients with PHPT. Serum calc...

journal_title：Endocrine

authors： Korkmaz H,Sirin FB,Torus B

更新日期：2020-09-28 00:00:00

abstract：PURPOSE:Bisphenol-A (BPA) is an endocrine-disrupting chemical that may affect the hormones and their receptors. The aim of this study is to determine whether BPA has an effect on the development of nonfunctional adrenal incidentaloma (NFAI). METHODS:Fifty patients who were admitted to endocrinology outpatient clinics ...

journal_title：Endocrine

authors： Eker F,Gungunes A,Durmaz S,Kisa U,Celik ZR

更新日期：2020-09-23 00:00:00

abstract：PURPOSE:This study investigated trends in chronic glucocorticoid (GC) use in South Korea, and determined the association between chronic GC use and 5-year all-cause mortality. METHODS:A sample cohort was extracted from the South Korean National Health Insurance database. Patients prescribed a continuous dose of GC for...

journal_title：Endocrine

authors： Oh TK,Song IA

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:An increasing body of evidence suggests that dipeptidyl-peptidase 4 (DPP-4) inhibitors could play a role in the development of bullous pemphigoid. The knowledge regarding this association is based on case reports, pharmacovigilance database analyses, and observational studies. Data from randomized clinical tria...

journal_title：Endocrine

authors： Silverii GA,Dicembrini I,Nreu B,Montereggi C,Mannucci E,Monami M

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:Bone may regulate glucose homeostasis via uncarboxylated bioactive osteocalcin (ucOCN). This study explored whether changes in ucOCN and bone remodeling are associated with change in glucose homeostasis after biliopancreatic diversion (BPD). METHODS:In this secondary exploratory analysis of a 1-year prospectiv...

journal_title：Endocrine

authors： Turcotte AF,Grenier-Larouche T,Lacombe J,Carreau AM,Carpentier AC,Mac-Way F,Tchernof A,Richard D,Biertho L,Lebel S,Marceau S,Ferron M,Gagnon C

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:The hyperthermal liquid, spray and smog caused by energy-based surgical devices (EBDs) may be the potential risk factors for recurrent laryngeal nerve (RLN) thermal injury, but not been reported previously. We aim to demonstrated it both in thyroid surgeries and animal experiments. METHODS:321 thyroid patients...

journal_title：Endocrine

authors： Yu X,Liu C,Yan M,Gong W,Wang Y

更新日期：2020-08-10 00:00:00

abstract：PURPOSE:The study aimed to disclose mortality pattern and quantitatively evaluate risks for cause-specific mortality among thyroid cancer survivors. METHODS:We included 173,710 patients from the Surveillance, Epidemiology, and End Results (SEER) database with thyroid cancer diagnosed between 1975 and 2015. Standardize...

journal_title：Endocrine

authors： Du B,Wang F,Wu L,Wang Z,Zhang D,Huang Z,Gao L,Li Y,Liang C,Li P,Yao R

更新日期：2020-08-08 00:00:00

abstract：BACKGROUND:Wolfram syndrome (WFS) is a rare, monogenic neurodegenerative syndrome characterised by insulin requiring non-autoimmune diabetes mellitus (DM) and optic atrophy which are usually the earliest and commonest manifestations. However, there are other features which are under-recognized, adding to morbidity and ...

journal_title：Endocrine

authors： Das L,Rai A,Mavuduru R,Vaiphei K,Sharma A,Gupta V,Bhadada SK,Lodha S,Panda N,Bhansali A,Singh P,Dutta P

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND AND AIM:A close relationship between adiposity and increased cortisol levels is well established in patients with endogenous hypercortisolism. Nevertheless, hypothalamic-pituitary-adrenal (HPA) axis regulation in overweight subjects is still a matter of concern. We studied free cortisol (urinary free cortiso...

journal_title：Endocrine

authors： Ceccato F,Lizzul L,Barbot M,Scaroni C

更新日期：2020-08-01 00:00:00

abstract：CONTEXT:To prepare for radioactive iodine therapy in post total thyroidectomy patients with well-differentiated thyroid cancer (WDTC), either thyroid hormone withdrawal (THW) or administration of recombinant human thyrotropin (rhTSH) can be performed. OBJECTIVE:Our objective is to compare quality of life (QoL) paramet...

journal_title：Endocrine

authors： Tang CYL,Thang SP,Zaheer S,Kwan CK,Ng DC

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Data on the prevalence and type of endocrine disorders in β-thalassemia intermedia (β-TI) patients are scarce. This multicenter study was designed to determine the prevalence of endocrine complications and the associated risk factors in a large group of β-TI patients. METHODS:In this cross-sectional multice...

journal_title：Endocrine

authors： Karimi M,Zarei T,Haghpanah S,Azarkeivan A,Kattamis C,Ladis V,Kattamis A,Kilinc Y,Daar S,Alyaarubi S,Khater D,Wali Y,Elshinawy M,Almadhani A,Yassin M,Soliman AT,Canatan D,Obiedat M,Al-Rimawi H,Mariannis D,Christodo

更新日期：2020-07-01 00:00:00

abstract：PURPOSE:In previous studies, associations between breast-milk cortisol levels obtained on one occasion and infant neurodevelopment were demonstrated. However, more recent evidence indicates that breast-milk cortisol and cortisone concentrations follow the diurnal rhythm of maternal hypothalamus-pituitary-adrenal axis, ...

journal_title：Endocrine

authors： Toorop AA,van der Voorn B,Hollanders JJ,Dijkstra LR,Dolman KM,Heijboer AC,Rotteveel J,Honig A,Finken MJJ

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:The institutional database of the Thyroid Surgery Division in China-Japan Union Hospital of Jilin University was queried to audit time trend patterns in thyroid cancer (TC) management between 2008 and 2017. METHODS:Retrospective longitudinal analysis. Clinicopathological features and treatment strategies were ...

journal_title：Endocrine

authors： Sui C,Liang N,Du R,He Q,Zhang D,Li F,Fu Y,Dionigi G,Sun H

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To perform an online survey about the use of Thyroid Imaging Reporting and Data System (TIRADS) classification in Italy. METHODS:An online questionnaire was administered to all members of the Italian Society of Medical and Interventional Radiology (Società Italiana di Radiologia Medica ed Interventistica, SIRM...

journal_title：Endocrine

authors： Mauri G,Gitto S,Cantisani V,Vallone G,Schiavone C,Papini E,Sconfienza LM

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:Diabetes mellitus (DM) has a multifactorial etiology that imparts a particular challenge to effective pharmacotherapy. Thyroid hormone actions have demonstrated beneficial effects in diabetic as well as obese rats. In both conditions, inflammation status plays a crucial role in the development of insulin resist...

journal_title：Endocrine

authors： Panveloski-Costa AC,Kuwabara WMT,Munhoz AC,Lucena CF,Curi R,Carpinelli AR,Nunes MT

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:Negative-pressure wound therapy (NPWT) is an adjunct modality in diabetic foot ulcerations (DFUs). Randomized controlled trials (RCTs) have shown its advantage over standard approaches; however, data from observational studies remain scarce.We performed a systematic review of observational non-RCTs evaluating N...

journal_title：Endocrine

authors： Rys P,Borys S,Hohendorff J,Zapala A,Witek P,Monica M,Frankfurter C,Ludwig-Slomczynska A,Kiec-Wilk B,Malecki MT

更新日期：2020-04-01 00:00:00

abstract：PURPOSE:In morbid obesity nonalcoholic fatty liver disease (NAFLD) is endemic. Aim of this study is to evaluate the diagnostic accuracy of the most common noninvasive methods for identify NAFLD and fibrosis in a cohort of morbid obese population. METHODS:Ninety morbid obese patients undergoing bariatric surgery (BS) a...

journal_title：Endocrine

authors： Coccia F,Testa M,Guarisco G,Bonci E,Di Cristofano C,Silecchia G,Leonetti F,Gastaldelli A,Capoccia D

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:Fatty acid binding protein 4 (FABP4) has been demonstrated to be secreted from adipocytes in an unconventional pathway associated with lipolysis. Circulating FABP4 is elevated in metabolic disorders and has been shown to affect various peripheral cells such as pancreatic β-cells, hepatocytes and macrophages, bu...

journal_title：Endocrine

authors： Dou HX,Wang T,Su HX,Gao DD,Xu YC,Li YX,Wang HY

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:To describe sex-related differences in self-care; to identify determinants of self-care according to sex, and to investigate how sex interacts with the effect of clinical and socio-demographic variables on self-care in adults with Type 2 Diabetes Mellitus (T2DM). METHODS:Cross-sectional multicentre study with ...

journal_title：Endocrine

authors： Caruso R,Rebora P,Luciani M,Di Mauro S,Ausili D

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:Hyponatremia is the most common electrolyte disorder in hospitalized patients, and its etiopathogenesis is related to an underlying tumor in 14% of cases. Hyponatremia has been associated with a worse outcome in several pathologies, including cancer, in which the leading cause of this electrolyte alteration is ...

journal_title：Endocrine

authors： Marroncini G,Fibbi B,Errico A,Grappone C,Maggi M,Peri A

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:Parathyroid cancer is a rare tumor associated with poor prognosis particularly when disseminated. While chemotherapy and/or radiotherapy are of no clinical value in disseminated disease, immunotherapy should be considered. SUBJECT AND RESULTS:A patient with CDC73-associated metastatic parathyroid carcinoma was...

journal_title：Endocrine

authors： Sarquis M,Marx SJ,Beckers A,Bradwell AR,Simonds WF,Bicalho MAC,Daly AF,Betea D,Friedman E,De Marco L

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:The evaluation of skeletal fragility in Cushing's syndrome (CS) is a clinical challenge, since dual-energy X-ray absorptiometry (DXA) does not capture abnormalities in bone microstructure induced by glucocorticoid excess. Hypercortisolism was shown to increase bone marrow adiposity, but it is still unknown whet...

journal_title：Endocrine

authors： Ferraù F,Giovinazzo S,Messina E,Tessitore A,Vinci S,Mazziotti G,Lania A,Granata F,Cannavò S

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:In the general population, sleep disorders are associated with an increased risk of cognitive impairment. The prevalence of sleep disorders, such as sleep apnea, in acromegalic patients is higher than in the general population, and they may have additional risk of cognitive impairment due to acromegaly treatmen...

journal_title：Endocrine

authors： Wennberg A,Lorusso R,Dassie F,Benavides-Varela S,Parolin M,De Carlo E,Fallo F,Mioni R,Vettor R,Semenza C,Maffei P

更新日期：2019-12-01 00:00:00

abstract：:The Metastatic progression of solid tumors, such as thyroid cancer is a complex process which involves various factors. Current understanding on the role of epithelial-mesenchymal transition (EMT) in thyroid carcinomas suggests that EMT is implicated in the progression from follicular thyroid cancer (FTC) and papillar...

journal_title：Endocrine

authors： Shakib H,Rajabi S,Dehghan MH,Mashayekhi FJ,Safari-Alighiarloo N,Hedayati M

更新日期：2019-12-01 00:00:00

abstract：PURPOSES:Parathyroid cancer (PC) is rare, but fatal condition. Preoperative prediction of PC remains challenging but meaningful. The aim of this study was to determine an effective model to predict PC in patients with parathyroid lesions >1.5 cm. METHODS:In this retrospective case-control study, we enrolled 30 patient...

journal_title：Endocrine

authors： Liu R,Xia Y,Chen C,Ye T,Huang X,Ma L,Hu Y,Jiang Y

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Thyroid hormone (TH) metabolism can have prognostic significance in brain tumors. We studied the association of common variations in three deiodinase gene single-nucleotide polymorphisms (SNPs) with circulating TH concentrations and prognosis of brain tumor patients. METHODS:Patients admitted for glioma and...

journal_title：Endocrine

authors： Bunevicius A,Laws ER,Saudargiene A,Tamasauskas A,Iervasi G,Deltuva V,Smith TR,Bunevicius R

更新日期：2019-12-01 00:00:00

abstract：:To evaluate the role of central subfield thickness (CST), cube average thickness (CAT), and cube volume (CV) as imaging biomarkers for severity of diabetic retinopathy within the ETDRS-based grades of retinopathy using spectral domain optical coherence tomography (SD-OCT). This study aims to evaluate the role of macul...

journal_title：Endocrine

authors： Saxena S,Caprnda M,Ruia S,Prasad S,Ankita,Fedotova J,Kruzliak P,Krasnik V

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:A retrospective analysis was carried out from patients and controls during the past 5 years from a series of studies investigating endothelial microparticles (MP). METHODS:In total, 319 samples from 207 individuals were included in this analysis, from patients with type 2 diabetes (T2D, n = 105), women with...

journal_title：Endocrine

authors： Al-Qaissi A,Alqarni S,Javed Z,Atkin SL,Sathyapalan T,Vince RV,Madden LA

更新日期：2019-11-01 00:00:00