听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览JOURNAL OF VASCULAR RESEARCH期刊下所有文献
  • Polarized Proteins in Endothelium and Their Contribution to Function.

    abstract::Protein localization in endothelial cells is tightly regulated to create distinct signaling domains within their tight spatial restrictions including luminal membranes, abluminal membranes, and interendothelial junctions, as well as caveolae and calcium signaling domains. Protein localization in endothelial cells is a...

    journal_title:Journal of vascular research

    pub_type: 杂志文章,评审

    doi:10.1159/000512618

    authors: Wolpe AG,Ruddiman CA,Hall PJ,Isakson BE

    更新日期:2021-01-27 00:00:00

  • The Effects of a Simulated Workday of Prolonged Sitting on Seated versus Supine Blood Pressure and Pulse Wave Velocity in Adults with Overweight/Obesity and Elevated Blood Pressure.

    abstract::We evaluated the effects of a simulated workday of prolonged sitting on blood pressure (BP) and pulse wave velocity (PWV) and examined whether posture (seated vs. supine) affected responses. Participants (n = 25) were adults, with overweight/obesity and elevated BP, and performed seated desk work for 7.5 h. BP and PWV...

    journal_title:Journal of vascular research

    pub_type: 杂志文章,随机对照试验

    doi:10.1159/000510294

    authors: Alansare AB,Kowalsky RJ,Jones MA,Perdomo SJ,Stoner L,Gibbs BB

    更新日期:2020-01-01 00:00:00

  • Evaluation of Biodegradable Stent Graft Coatings in Pig and Rabbit Models.

    abstract:AIMS:Percutaneous coronary intervention is routinely performed to treat occlusive coronary artery disease. Coronary perforation is a potential complication and can be treated with a stent graft. Current stent grafts are associated with high restenosis rates. We tested the safety and feasibility of biodegradable stent g...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000505454

    authors: Taavitsainen J,Tarvainen S,Kuivanen A,Mangiardi EK,Guelcher M,Martin J,Mathur A,Hytönen JP,Ylä-Herttuala S

    更新日期:2020-01-01 00:00:00

  • Cigarette Smoke Extract Activates Tartrate-Resistant Acid Phosphatase-Positive Macrophage.

    abstract:BACKGROUND:It has been reported that smoking is one of the strongest positive risk factors for abdominal aortic aneurysms (AAAs). Although many studies have been directed to decipher the effect of smoking on AAA, its effect on macrophage activation has not yet been explored. OBJECTIVES:We have reported the importance ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000498893

    authors: Igari K,Kelly MJ,Yamanouchi D

    更新日期:2019-01-01 00:00:00

  • Tumor Necrosis Factor Receptor-Associated Factor 5 Promotes Arterial Neointima Formation through Smooth Muscle Cell Proliferation.

    abstract::Tumor necrosis factor (TNF) receptor-associated factors (TRAFs) are cytoplasmic adaptor proteins of the TNF/interleukin (IL)-1/Toll-like receptor superfamily. Ligands of this family such as TNFα, CD40L, and IL-1β promote chronic inflammatory processes such as atherosclerosis and restenosis, the latter being a common a...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000501615

    authors: Willecke F,Rupprecht B,Gissler MC,Pfeiffer K,Anto-Michel N,Stachon P,Wolf D,Hilgendorf I,Hoppe N,Bode C,Zirlik A

    更新日期:2019-01-01 00:00:00

  • Pulse Waveform Analysis in Ocular Microcirculation by Laser Speckle Flowgraphy in Patients with Left Ventricular Systolic and Diastolic Dysfunction.

    abstract:PURPOSE:To determine: (1) whether variables of a pulse wave form analysis of ocular microcirculation shown by laser speckle flowgraphy (LSFG) correlate with left ventricular (LV) systolic dysfunction and (2) whether these variables correlate with LV diastolic dysfunction in subjects without LV systolic dysfunction as a...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000494066

    authors: Shiba T,Takahashi M,Matsumoto T,Hori Y

    更新日期:2018-01-01 00:00:00

  • Remodeling of Wall Mechanics and the Myogenic Mechanism of Rat Intramural Coronary Arterioles in Response to a Short-Term Daily Exercise Program: Role of Endothelial Factors.

    abstract:PURPOSE:Exercise elicits early adaptation of coronary vessels enabling the coronary circulation to respond adequately to higher flow demands. We hypothesized that short-term daily exercise induces biomechanical and functional remodeling of the coronary resistance arteries related to pressure. METHODS:Male rats were su...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000486571

    authors: Szekeres M,Nádasy GL,Dörnyei G,Szénási A,Koller A

    更新日期:2018-01-01 00:00:00

  • Aging-Induced Modulation of Pituitary Adenylate Cyclase-Activating Peptide- and Vasoactive Intestinal Peptide-Induced Vasomotor Responses in the Arteries of Mice.

    abstract::Pituitary adenylate cyclase-activating peptide (PACAP; 1-38 and 1-27) and vasoactive intestinal peptide (VIP) are related neuropeptides of the secretin/glucagon family. Overlapping signaling through G-protein-coupled receptors mediates their vasomotor activity. We previously showed that PACAP deficiency (PACAP-KO) shi...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000481781

    authors: Ivic I,Solymar M,Fulop BD,Hashimoto H,Toth G,Tamas A,Juhasz T,Koller A,Reglodi D

    更新日期:2017-01-01 00:00:00

  • Epigallocatechin-3-Gallate Ameliorates Angiotensin II-Induced Oxidative Stress and Apoptosis in Human Umbilical Vein Endothelial Cells through the Activation of Nrf2/Caspase-3 Signaling.

    abstract:INTRODUCTION:This study aimed to investigate whether epigallocatechin-3-gallate (EGCG) shows antioxidant activity against angiotensin II (Ang II)-induced human umbilical vein endothelial cell (HUVEC) apoptosis. MATERIALS AND METHODS:The viability of HUVECs was revealed by MTT and LDH assay. The cell apoptosis was dete...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000479873

    authors: Zhou X,Liang L,Zhao Y,Zhang H

    更新日期:2017-01-01 00:00:00

  • Dysregulation of Vascular Endothelial Growth Factor Receptor-2 by Multiple miRNAs in Endothelial Colony-Forming Cells of Coronary Artery Disease.

    abstract:BACKGROUND/AIMS:Endothelial colony-forming cells (ECFCs) have the potential to be used in regenerative medicine. Dysfunction of ECFCs is correlated with the onset of cardiovascular disorders, especially coronary artery disease (CAD). Binding of vascular endothelial growth factor A (VEGFA) to vascular endothelial growth...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000449202

    authors: Su SH,Wu CH,Chiu YL,Chang SJ,Lo HH,Liao KH,Tsai CF,Tsai TN,Lin CH,Cheng SM,Cheng CC,Wang HW

    更新日期:2017-01-01 00:00:00

  • Tauroursodeoxycholic Acid Reduces Arterial Stiffness and Improves Endothelial Dysfunction in Type 2 Diabetic Mice.

    abstract:BACKGROUND/AIMS:Endoplasmic reticulum (ER) stress has emerged as a potential mechanism contributing to diabetes and its comorbidities. However, the importance of ER stress in diabetic vascular dysfunction is unclear. The purpose of this study was to examine the effects of the ER stress inhibitor, tauroursodeoxycholic a...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000479967

    authors: Battson ML,Lee DM,Jarrell DK,Hou S,Ecton KE,Phan AB,Gentile CL

    更新日期:2017-01-01 00:00:00

  • Changes in IP3 Receptor Expression and Function in Aortic Smooth Muscle of Atherosclerotic Mice.

    abstract::Peroxynitrite is an endothelium-independent vasodilator that induces relaxation via membrane hyperpolarization. The activation of IP3 receptors triggers the opening of potassium channels and hyperpolarization. Previously we found that relaxation to peroxynitrite was maintained during the development of atherosclerosis...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000461581

    authors: Ewart MA,Ugusman A,Vishwanath A,Almabrouk TAM,Alganga H,Katwan OJ,Hubanova P,Currie S,Kennedy S

    更新日期:2017-01-01 00:00:00

  • Protective Function of Ahnak1 in Vascular Healing after Wire Injury.

    abstract:AIM:Vascular remodeling following injury substantially accounts for restenosis and adverse clinical outcomes. In this study, we investigated the role of the giant scaffold protein Ahnak1 in vascular healing after endothelial denudation of the murine femoral artery. METHODS:The spatiotemporal expression pattern of Ahna...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000464287

    authors: Haase N,Rüder C,Haase H,Kamann S,Kouno M,Morano I,Dechend R,Zohlnhöfer D,Haase T

    更新日期:2017-01-01 00:00:00

  • Circulating Concentrations of Adipocytokines and Their Receptors in the Isolated Corpus Cavernosum and Femoral Artery from Trained Rats on a High-Fat Diet.

    abstract:BACKGROUND:The aim of the present study was to evaluate different signaling pathways by which exercise training would interfere in endothelial function in obesity. Therefore, we examined adipocytokine levels and their receptors in the corpus cavernosum and femoral artery from trained rats on a high-fat diet. METHODS:F...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000457800

    authors: Sponton AC,Silva FH,Araujo HN,Valgas da Silva CP,de Moraes C,Antunes E,Zanesco A,Delbin MA

    更新日期:2017-01-01 00:00:00

  • Direct Evidence for P2Y2 Receptor Involvement in Vascular Response to Injury.

    abstract:OBJECTIVES:Extracellular nucleotide release at the site of arterial injury mediates the proliferation and migration of vascular smooth muscle cells. Our aim was to investigate the role of the P2Y2 nucleotide receptor (P2Y2R) in neointimal hyperplasia. Approach and Results: Vascular injury was induced by the implantatio...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000449059

    authors: Agca Y,Qian S,Agca C,Seye CI

    更新日期:2016-01-01 00:00:00

  • Hyperglycemia and Advanced Glycation End Products Regulate miR-126 Expression in Endothelial Progenitor Cells.

    abstract:BACKGROUND/AIMS:Dysfunction of endothelial progenitor cell (EPCs) contributes to diabetic vascular disease. We reported that downregulated miR-126 in diabetic patients causes EPC dysfunction. The study was designed to investigate how high glucose (HG) and advanced glycation end products (AGEs) regulate miR-126 expressi...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000448713

    authors: Li Y,Zhou Q,Pei C,Liu B,Li M,Fang L,Sun Y,Li Y,Meng S

    更新日期:2016-01-01 00:00:00

  • Differential Regulation of BMAL1, CLOCK, and Endothelial Signaling in the Aortic Arch and Ligated Common Carotid Artery.

    abstract::The circadian clock is rhythmically expressed in blood vessels, but the interaction between the circadian clock and disturbed blood flow remains unclear. We examined the relationships between BMAL1 and CLOCK and 2 regulators of endothelial function, AKT1 and endothelial nitric oxide synthase (eNOS), in vascular region...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000452410

    authors: Shang X,Pati P,Anea CB,Fulton DJ,Rudic RD

    更新日期:2016-01-01 00:00:00

  • Notch4 Signaling Pathway of Endothelial Progenitor Cells in a Kawasaki Disease Model Induced by Lactobacillus casei Cell Wall Extract.

    abstract::The Notch4 signaling pathway of endothelial progenitor cells (EPCs) may play a crucial role in Kawasaki disease (KD). We investigated the proliferation, adhesion, migration, angiogenesis, and expression levels of Notch4, recombination signal-binding protein-Jκ (RBP-Jκ), P-selectin, and vascular cell adhesion molecule-...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000449061

    authors: Wang H,Xia Y,Fu S,Wang W,Xie C,Zhang Y,Gong F

    更新日期:2016-01-01 00:00:00

  • Extra- and Intraluminal Elastase Induce Morphologically Distinct Abdominal Aortic Aneurysms in Mice and Thus Represent Specific Subtypes of Human Disease.

    abstract::Topical application of elastase to induce arterial aneurysm formation is an emerging murine model of vascular disease. In the context of aortic abdominal aneurysm (AAA), angiotensin II infusion and porcine pancreatic elastase perfusion models are commonly used today. This study, therefore, compares matrix remodeling, ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000447263

    authors: Busch A,Holm A,Wagner N,Ergün S,Rosenfeld M,Otto C,Baur J,Kellersmann R,Lorenz U

    更新日期:2016-01-01 00:00:00

  • Transplantation of Autologous Bone Marrow Mononuclear Cells Regulates Inflammation in a Rabbit Model of Carotid Artery Atherosclerosis.

    abstract:OBJECTIVE:It is well known that inflammation plays key roles in the development of atherosclerosis and that the transplantation of bone marrow mononuclear cells (BMMNCs) can suppress inflammation in rodent models of ischemic diseases. Here, we explored whether transplantation of autologous BMMNCs could prevent the prog...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000449201

    authors: Cui K,Wang M,Yu L,Ren X,Cui H,Yu XF,Hou S,Fu C,Wang J

    更新日期:2016-01-01 00:00:00

  • Glucagon-Like Peptide-1 Receptor Activation Does not Affect Re-Endothelialization but Reduces Intimal Hyperplasia via Direct Effects on Smooth Muscle Cells in a Nondiabetic Model of Arterial Injury.

    abstract:UNLABELLED:Diabetic patients have an increased risk of restenosis and late stent thrombosis after angioplasty, i.e. complications that are related to a defective re-endothelialization. Exendin-4, a stable glucagon-like peptide (GLP)-1 receptor agonist, has been suggested to influence the formation of intimal hyperplasi...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000381097

    authors: Eriksson L,Saxelin R,Röhl S,Roy J,Caidahl K,Nyström T,Hedin U,Razuvaev A

    更新日期:2015-01-01 00:00:00

  • Elastin organization in pig and cardiovascular disease patients' pericardial resistance arteries.

    abstract::Peripheral vascular resistance is increased in essential hypertension. This involves structural changes of resistance arteries and stiffening of the arterial wall, including remodeling of the extracellular matrix. We hypothesized that biopsies of the human parietal pericardium, obtained during coronary artery bypass g...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000376548

    authors: Bloksgaard M,Leurgans TM,Nissen I,Jensen PS,Hansen ML,Brewer JR,Bagatolli LA,Marcussen N,Irmukhamedov A,Rasmussen LM,De Mey JG

    更新日期:2015-01-01 00:00:00

  • Pericyte dynamics during angiogenesis: new insights from new identities.

    abstract::Therapies aimed at manipulating the microcirculation require the ability to control angiogenesis, defined as the sprouting of new capillaries from existing vessels. Blocking angiogenesis would be beneficial in many pathologies (e.g. cancer, retinopathies and rheumatoid arthritis). In others (e.g. myocardial infarction...

    journal_title:Journal of vascular research

    pub_type: 杂志文章,评审

    doi:10.1159/000362276

    authors: Stapor PC,Sweat RS,Dashti DC,Betancourt AM,Murfee WL

    更新日期:2014-01-01 00:00:00

  • Lipoxin A4 mediates aortic contraction via RHOA/RHO kinase, endothelial dysfunction and reactive oxygen species.

    abstract:BACKGROUND:Lipoxin A4 (LXA4) is a biologically active product generated from arachidonic acid by lipoxygenase action. The production of lipoxins is enhanced by aspirin through acetylation of cyclooxygenase-2, via a mechanism known as 'aspirin-triggered lipoxin'. LXA4 has both anti-inflammatory and proinflammatory actio...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000371490

    authors: Wenceslau CF,McCarthy CG,Szasz T,Webb RC

    更新日期:2014-01-01 00:00:00

  • Blood outgrowth endothelial cells reduce hypoxia-mediated fibroblast to myofibroblast conversion by decreasing proangiogenic cytokines.

    abstract:PURPOSE:Hypoxic conditions cause fibroblasts to differentiate into alpha smooth-muscle cell actin (α -SMA)-positive cells, i.e. myofibroblasts. This process is a hallmark of venous neointimal hyperplasia (VNH) associated with hemodialysis vascular access. The purpose of this study was to determine if blood outgrowth en...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000369929

    authors: Nieves Torres EC,Yang B,Brahmbhatt A,Mukhopadhyay D,Misra S

    更新日期:2014-01-01 00:00:00

  • Changes in adrenoceptors and G-protein-coupled receptor kinase 2 in L-NAME-induced hypertension compared to spontaneous hypertension in rats.

    abstract::This work compares the expression of adrenoceptors (ARs) and G-protein-coupled receptor kinase (GRK) 2 (RT-PCR and immunoblotting) and functional responses in conductance (aorta) and resistance vessels (mesenteric resistance arteries; MRA) in two different models of rat hypertension: hypertension induced by chronic tr...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000360400

    authors: Oliver E,Flacco N,Arce C,Ivorra MD,D'Ocon MP,Noguera MA

    更新日期:2014-01-01 00:00:00

  • DMSO-soluble cigarette smoke particles alter the expression of endothelin B receptor in rat coronary artery.

    abstract::In coronary artery diseases, cigarette smoking is a risk factor and the endothelin system plays a key role in the pathogenesis. This study was to examine if dimethylsulfoxide-soluble smoke particles (DSP) upregulate endothelin type-B (ETB) receptors in the coronary artery and investigate the mechanism. The isolated ra...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000350866

    authors: Huang LH,Zhang PA,He JY,Liu J,Cao YX

    更新日期:2013-01-01 00:00:00

  • Coordinated endothelial nitric oxide synthase activation by translocation and phosphorylation determines flow-induced nitric oxide production in resistance vessels.

    abstract:BACKGROUND/AIMS:Endothelial nitric oxide synthase (eNOS) is associated with caveolin-1 (Cav-1) in plasma membrane. We tested the hypothesis that eNOS activation by shear stress in resistance vessels depends on synchronized phosphorylation, dissociation from Cav-1 and translocation of the membrane-bound enzyme to Golgi ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000355301

    authors: Figueroa XF,González DR,Puebla M,Acevedo JP,Rojas-Libano D,Durán WN,Boric MP

    更新日期:2013-01-01 00:00:00

  • Role of HOXA9 and VEZF1 in endothelial biology.

    abstract::Proper development of the vascular system as one of the earliest and most critical steps during vertebrate embryogenesis is ensured by the exact spatial and temporal control of gene expression in cells forming the vessel network. Whereas the regulation of vascular system development is well elucidated on the level of ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章,评审

    doi:10.1159/000353287

    authors: Bruderer M,Alini M,Stoddart MJ

    更新日期:2013-01-01 00:00:00

  • Hypoxia does neither stimulate pulmonary artery endothelial cell proliferation in mice and rats with pulmonary hypertension and vascular remodeling nor in human pulmonary artery endothelial cells.

    abstract:BACKGROUND:Hypoxia results in pulmonary hypertension and vascular remodeling due to induction of pulmonary artery cell proliferation. Besides pulmonary artery smooth muscle cells, pulmonary artery endothelial cells (PAECs) are also involved in the development of pulmonary hypertension, but the effect of hypoxia on PAEC...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000327005

    authors: Yu L,Hales CA

    更新日期:2011-01-01 00:00:00

  • Oxygen-dependent vasomotor responses are conducted upstream in the mouse cremaster microcirculation.

    abstract:BACKGROUND:A new method was evaluated where local changes in oxygen tension were induced in a tissue while being studied under a microscope in vivo. We tested whether hypoxic vasodilation and hyperoxic vasoconstriction in arterioles in striated muscle are being propagated upstream, and whether the endothelium and smoot...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000318777

    authors: Riemann M,Rai A,Ngo AT,Dziegiel MH,Holstein-Rathlou NH,Torp-Pedersen C

    更新日期:2011-01-01 00:00:00

  • Connexin channel-dependent signaling pathways in inflammation.

    abstract::Inflammation is a highly regulated process with common but also specific characteristics in each tissue affected. Recruitment of leukocytes from the blood to the injured tissue is an important early step in the inflammatory cascade. This review highlights the role of connexins (Cxs) in the regulation of both acute and...

    journal_title:Journal of vascular research

    pub_type: 杂志文章,评审

    doi:10.1159/000316942

    authors: Scheckenbach KE,Crespin S,Kwak BR,Chanson M

    更新日期:2011-01-01 00:00:00

  • Role of lysyl oxidases in neointima development in vascular allografts.

    abstract:BACKGROUND:Extracellular matrix deposition is the main factor inducing stenotic lesions in arterial grafts. Lysyl oxidases (LOX) play a key role in stabilizing collagen and elastin. OBJECTIVE:To examine the repair response to arterial allografts in terms of LOX expression and collagen/elastin deposition using LOX inhi...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000317399

    authors: Rodríguez M,Pascual G,Cifuentes A,Perez-Köhler B,Bellón JM,Buján J

    更新日期:2011-01-01 00:00:00

  • Insulin increases acid production and may directly stimulate Na/H(+) exchange activity in cultured vascular smooth muscle cells.

    abstract::Insulin was reported to decrease Na(+)/H(+) exchange activity in murine vascular smooth muscle (VSM) tissue. In most other cells, insulin increases activity. We tested the effects of insulin on Na(+)/H(+) exchange activity in primary cultured canine VSM cells. Intracellular pH (pH(i)) was measured with 2',7'-bis(2-car...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000329587

    authors: Kahn AM,Yang M

    更新日期:2011-01-01 00:00:00

  • Hyperuricemia attenuates aortic nitric oxide generation, through inhibition of arginine transport, in rats.

    abstract:OBJECTIVES:Hyperuricemia provokes endothelial dysfunction (ECD). Decreased endothelial nitric oxide synthase (eNOS) activity is an important source of ECD. Cationic amino acid transporter-1 (CAT-1) is the specific arginine transporter for eNOS. We hypothesize that hyperuricemia inhibits arginine uptake. METHODS:Experi...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000320356

    authors: Schwartz IF,Grupper A,Chernichovski T,Grupper A,Hillel O,Engel A,Schwartz D

    更新日期:2011-01-01 00:00:00

  • Focused in vivo delivery of plasmid DNA to the porcine vascular wall via intravascular ultrasound destruction of microbubbles.

    abstract:BACKGROUND:Safety concerns associated with drug-eluting stents have spurred interest in alternative vessel therapeutics following angioplasty. Microbubble contrast agents have been shown to increase gene transfection in vivo in the presence of ultrasound. OBJECTIVES/METHODS:The purpose of this study was to determine w...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000258905

    authors: Phillips LC,Klibanov AL,Bowles DK,Ragosta M,Hossack JA,Wamhoff BR

    更新日期:2010-01-01 00:00:00

  • Oxidized low-density lipoprotein induces apoptosis in endothelial progenitor cells by inactivating the phosphoinositide 3-kinase/Akt pathway.

    abstract::We tested the hypothesis that oxidized low-density lipoprotein (oxLDL)-induced inactivation of Akt within endothelial progenitor cells (EPCs) is mediated at the level of phosphoinositide 3-kinase (PI3K), specifically by nitrosylation of the p85 subunit of PI3K, and that this action is critical in provoking oxLDL-induc...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000313879

    authors: Tie G,Yan J,Yang Y,Park BD,Messina JA,Raffai RL,Nowicki PT,Messina LM

    更新日期:2010-01-01 00:00:00

  • Transglutaminase 2 deficiency decreases plaque fibrosis and increases plaque inflammation in apolipoprotein-E-deficient mice.

    abstract:AIM:Transglutaminase 2 (TG2) is important for the deposition and stability of the extracellular matrix via effects on cross-linking of matrix proteins and transforming growth factor beta (TGFbeta) activity. The purpose of this study was to investigate the effect of TG2 deficiency on the composi- tion of atherosclerotic...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000255966

    authors: Van Herck JL,Schrijvers DM,De Meyer GR,Martinet W,Van Hove CE,Bult H,Vrints CJ,Herman AG

    更新日期:2010-01-01 00:00:00

  • Diminished insulin-mediated forearm blood flow and muscle glucose uptake in young men with low birth weight.

    abstract:BACKGROUND:Low birth weight (LBW) is associated with increased risk of type 2 diabetes and cardiovascular disease. We studied endothelial function and insulin sensitivity in young men with LBW (n = 22) and controls (n = 22). METHODS:Insulin sensitivity and endothelial function was studied with venous occlusion plethys...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000235968

    authors: Sonne MP,Højbjerre L,Alibegovic AC,Vaag A,Stallknecht B,Dela F

    更新日期:2010-01-01 00:00:00

  • Visualization of activated platelets by targeted magnetic resonance imaging utilizing conformation-specific antibodies against glycoprotein IIb/IIIa.

    abstract::Ruptured atherosclerotic plaques, lined with activated platelets, constitute an attractive target for magnetic resonance imaging (MRI). This study evaluated whether microparticles of iron oxide (MPIO) targeting ligand-induced binding sites (LIBS) on the activated conformation of glycoprotein IIb/IIIa could be used to ...

    journal_title:Journal of vascular research

    pub_type: 杂志文章

    doi:10.1159/000135660

    authors: von zur Muhlen C,Peter K,Ali ZA,Schneider JE,McAteer MA,Neubauer S,Channon KM,Bode C,Choudhury RP

    更新日期:2009-01-01 00:00:00

123 条记录 1/4 页 « 1234 »