abstract：Purpose:Undertreatment of trauma-related pain is common in the pre-hospital and hospital settings owing to barriers to the use of traditional standard of care analgesics. Low-dose methoxyflurane is an inhaled non-opioid analgesic with a rapid onset of pain relief that is approved for emergency relief of moderate-to-sev...

journal_title：Journal of pain research

authors： Fabbri A,Borobia AM,Ricard-Hibon A,Coffey F,Caumont-Prim A,Montestruc F,Soldi A,Traseira Lugilde S,Dickerson S

更新日期：2021-01-20 00:00:00

abstract：Background:Despite the increasing prevalence of opioid use disorder (OUD) in pregnant women, there are limited studies on their anesthesia care and analgesic outcomes after cesarean delivery (CD). Methods:Patients with OUD on either buprenorphine or methadone maintenance therapy who underwent CD at our institution fro...

journal_title：Journal of pain research

authors： Reno JL,Kushelev M,Coffman JH,Prasad MR,Meyer AM,Carpenter KM,Palettas MS,Coffman JC

更新日期：2020-12-30 00:00:00

abstract：Purpose:Primary dysmenorrhea (PD; menstrual pain without an identified organic cause) has been proposed as a possible risk factor for the development of chronic pelvic pain, but the mechanism through which this process occurs is unknown. One possible mechanism is central sensitization - alterations in the central nervo...

journal_title：Journal of pain research

authors： Seidman LC,Temme CR,Zeltzer LK,Rapkin AJ,Naliboff BD,Payne LA

更新日期：2020-12-22 00:00:00

abstract：Introduction:The sacroiliac joint (SIJ) has been estimated to contribute to pain in as much as 38% of cases of lower back pain. There are no clear diagnostic or treatment pathways. This article seeks to establish a clearer pathway and algorithm for treating patients. Methods:The literature was reviewed in order to rev...

journal_title：Journal of pain research

authors： Falowski S,Sayed D,Pope J,Patterson D,Fishman M,Gupta M,Mehta P

更新日期：2020-12-08 00:00:00

abstract：:Cancer and cancer treatment-related chronic pain affect a significant number of patients. The etiology of this pain is diverse and may include nociceptive and/or neuropathic characteristics. Treatment is often multifactorial and may require advanced interventional techniques, such as spinal cord stimulation (SCS). Thi...

journal_title：Journal of pain research

authors： Hagedorn JM,Pittelkow TP,Hunt CL,D'Souza RS,Lamer TJ

更新日期：2020-12-07 00:00:00

abstract：Purpose:Spinal cord stimulation (SCS) is a drug-free treatment for chronic neuropathic pain. Recent SCS technology can record evoked compound action potentials (ECAPs) in the spinal cord during therapy and utilize features of the sensed ECAP to optimize the SCS. The purpose of this work is to characterize the relevant ...

journal_title：Journal of pain research

authors： Chakravarthy K,Bink H,Dinsmoor D

更新日期：2020-12-04 00:00:00

abstract：Background:Low back pain is a prevalent symptom that occurs in all age of people, whereas the pathogenesis is unknown. Iliopsoas tendinopathy is an increasingly recognized hip disorder that may contribute to low back pain. Our purpose is to evaluate the effect of ultrasound-guided local injection of anesthetic and ster...

journal_title：Journal of pain research

authors： Zhu Z,Zhang J,Sheng J,Zhang C,Xie Z

更新日期：2020-11-20 00:00:00

abstract：Background:Millions of people worldwide are suffering from pain. Non-pharmacological therapy has an important role in the treatment of pain and is recognized as a valuable, simple help to lower the dosage of analgesic drugs needed, decreasing the side effects, reducing drug dependency and reducing health care costs; ho...

journal_title：Journal of pain research

authors： Jira L,Weyessa N,Mulatu S,Alemayehu A

更新日期：2020-11-16 00:00:00

abstract：:Ultrasound-guided cervical nerve root block is the technique of injecting local anesthetic or steroid into the intertubercular groove outside of the cervical foramen under real-time ultrasound guidance. It has established diagnostic and therapeutic employment for patients suffering symptoms caused by cervical disc dis...

journal_title：Journal of pain research

authors： Zhang S,Fan L,Mei W

更新日期：2020-10-14 00:00:00

abstract：Background:Regional variations of opioid use have been reported from many countries. The objective of this study was to examine opioid prescribing patterns in Germany including low- and high-potency opioids (LPO and HPO) focusing on regional differences. Methods:Data source was the "Information system for health care ...

journal_title：Journal of pain research

authors： Jobski K,Dörks M,Bantel C,Hoffmann F

更新日期：2020-10-07 00:00:00

abstract：Purpose:The aim of this prospective study was to assess the behavior of emergency department (ED) nurses with regard to pain and their role in pain management in a real-life clinical setting. Methods:A total of 509 consecutive patients were enrolled during a 6-week period. A case-report form was used to collect data o...

journal_title：Journal of pain research

authors： Sardo S,Galletta M,Coni E,Aviles Gonzalez CI,Piras I,Pia G,Evangelista M,Musu M,Finco G

更新日期：2020-09-22 00:00:00

abstract：Introduction:Cannabidiol (CBD) is reported to produce pain relief, but the clinically relevant cellular and molecular mechanisms remain uncertain. The TRPV1 receptor integrates noxious stimuli and plays a key role in pain signaling. Hence, we conducted in vitro studies, to elucidate the efficacy and mechanisms of CBD f...

journal_title：Journal of pain research

authors： Anand U,Jones B,Korchev Y,Bloom SR,Pacchetti B,Anand P,Sodergren MH

更新日期：2020-09-11 00:00:00

abstract：:[This corrects the article DOI: 10.2147/JPR.S203721.]. ...

journal_title：Journal of pain research

authors：

更新日期：2020-08-26 00:00:00

abstract：Background:It has been reported that N-cadherin and cAMP response element binding protein (CREB) in the spinal cord are critical for synaptogenesis and regulation of excitatory synapse function, which could underlie chronic pain development. The aim of the present study was to investigate the role of spinal N-cadherin/...

journal_title：Journal of pain research

authors： Ma Y,Zhang X,Li C,Liu S,Xing Y,Tao F

更新日期：2020-08-12 00:00:00

abstract：:Osteoarthritis (OA) is a common degenerative disease that affects the vast majority of the elderly and may eventually embark on the road of the total knee arthroplasty (TKA), although controversy still exists in the medical community about the best therapies for osteoarthritis. Compared with physical therapy, oral ana...

journal_title：Journal of pain research

authors： Zhang Y,Chen X,Tong Y,Luo J,Bi Q

更新日期：2020-08-04 00:00:00

abstract：Purpose:No final conclusion has yet been reached on characteristics of postoperative pain and pain-related factors after video-assisted thoracoscopic surgery (VATS). This study was designed to explore features of acute severe pain and chronic post-surgical pain (CPSP), and the pain-related factors of VATS. Patients an...

journal_title：Journal of pain research

authors： Tong Y,Wei P,Wang S,Sun Q,Cui Y,Ning N,Chen S,He X

更新日期：2020-07-21 00:00:00

abstract：Purpose:Post-herpetic neuralgia (PHN) is a common herpes zoster (HZ) complication, where pain persists 90 days after the initial HZ diagnosis. Evaluating PHN risk is essential for determining the burden on patients and health-care systems, but research shows variable estimates. The extent to which these differences are...

journal_title：Journal of pain research

authors： Tanenbaum HC,Lawless A,Sy LS,Hong V,Ackerson B,Bruxvoort K,Luo Y,Tseng HF

更新日期：2020-07-13 00:00:00

abstract：Purpose:The quadratus lumborum block (QLB) is a relatively new regional analgesic technique that could provide analgesia to the abdominal wall and reduce postoperative opioid consumption. We investigated the opioid-sparing effect of a unilateral lateral QLB in laparoscopic nephrectomy. Patients and Methods:A total of ...

journal_title：Journal of pain research

authors： Kwak KH,Baek SI,Kim JK,Kim TH,Yeo J

更新日期：2020-07-03 00:00:00

abstract：Background:Erector spinae plane block (ESPB) as a new trunk fascia block technique was proposed in 2016. ESPB has aroused the interest of many nerve block experts. However, there are few clinical studies on ESPB for lumbar surgery, and its effectiveness and safety are controversial. The goal of this review is to summar...

journal_title：Journal of pain research

authors： Qiu Y,Zhang TJ,Hua Z

更新日期：2020-07-01 00:00:00

abstract：Purpose:Although the use of opioids is increasing in South Korea, there have been no studies on the serious complications caused by the opioids. The aim of this study was to investigate the rare but serious complications through medicolegal analysis. Materials and Methods:From January 1994 to December 2019, we retrosp...

journal_title：Journal of pain research

authors： Kim J,Shin S,Jeong Y,Kim SY,Lee HJ

更新日期：2020-06-25 00:00:00

abstract：Background:Patients living with chronic upper limb and neck (ULN) pain are reliant on often ineffective therapies as they face limited options for effective long-term treatment. Objective:Prospective clinical studies have demonstrated that high-frequency spinal cord stimulation at 10 kHz (10 kHz SCS) is effective in t...

journal_title：Journal of pain research

authors： Sayed D,Salmon J,Khan TW,Sack AM,Braun T,Barnard A,Rotte A

更新日期：2020-06-15 00:00:00

abstract：Background:While the concomitant administration of painful and rewarding stimuli tends to reduce the perception of one another, recent evidence shows that pleasant pain relief is experience after the interruption of noxious stimuli. On neurobiological grounds, these opponent processes should translate into decreased ac...

journal_title：Journal of pain research

authors： Bitar N,Dugré JR,Marchand S,Potvin S

更新日期：2020-06-08 00:00:00

abstract：Purpose:The INTERMED instrument, which was developed to measure patient's biopsychosocial (BPS) complexity, represents a powerful diagnostic and therapeutic tool. Epigenetic changes are the interface between signals from the environment and genetic modifications, affecting gene expression, in particular, by DNA methyla...

journal_title：Journal of pain research

authors： Paoloni-Giacobino A,Luthi F,Stenz L,Le Carré J,Vuistiner P,Léger B

更新日期：2020-06-02 00:00:00

abstract：Background:Although the Eph receptor plays an important role in the development of neuropathic pain following nerve injury, there has been no evidence of the participation of the ephrin A4 receptor (EphA4) in the development of trigeminal neuropathic pain. The present study investigated the role of EphA4 in central noc...

journal_title：Journal of pain research

authors： Kim MJ,Son JY,Ju JS,Ahn DK

更新日期：2020-05-22 00:00:00

abstract：Purpose:The upregulation of spinal NMDA receptor is a crucial mechanism in remifentanil-induced hyperalgesia (RIH). Wnt3a/β-catenin pathway plays an important role in neuropathic pain. We hypothesized that wnt3a inhibitor (iwp-2) could downregulate the expression of NR2B subunit in NMDA receptor, in order to relieve R...

journal_title：Journal of pain research

authors： Gao Y,Zhou S,Pan Y,Gu L,He Y,Sun J

更新日期：2020-05-19 00:00:00

abstract：Purpose:The aim of this study was to evaluate postoperative discomfort in patients undergoing ambulatory strabismus under general anesthesia, and to identify risk factors associated with the discomfort. Patients and Methods:A cross-sectional study was conducted among 210 consecutive patients undergoing ambulatory stra...

journal_title：Journal of pain research

authors： Huang J,Lin J,Xiong Y,Wang Z,Zhu Y,Ye H,Guo W

更新日期：2020-05-05 00:00:00

abstract：Purpose:Exercise-induced hypoalgesia (EIH) is the short-term reduction of pain sensitivity after a single bout of exercise. Descending pain inhibition has been proposed to at least partly underlie EIH. Cognitive inhibition is the ability to inhibit a pre-potent response and has in turn been associated with descending p...

journal_title：Journal of pain research

authors： Gajsar H,Titze C,Konietzny K,Meyer M,Vaegter HB,Hasenbring MI

更新日期：2020-04-29 00:00:00

abstract：Objective:To report a rare case of spontaneous fusion (SF) following cervical disc arthroplasty (CDA), to review the related literature, and to propose a new measure to prevent it. Methods:The course of a patient with SF is described here. The potential causes, risk factors, and preventive measure of SF after CDA publ...

journal_title：Journal of pain research

authors： Ge CY,Wang J,Zhang BF,Hui H,Shan LQ,Zhao QP,Hao DJ

更新日期：2020-04-21 00:00:00

abstract：Purpose:Erector spinae plane block (ESPB) is a newly reported interfascial plane block in pain management, and it can block the nerves exactly in line with the area of the posterior lumbar surgery. The objective of this research was to determine the effectiveness of pre-operative ESPB in enhancing recovery of posterior...

journal_title：Journal of pain research

authors： Zhang TJ,Zhang JJ,Qu ZY,Zhang HY,Qiu Y,Hua Z

更新日期：2020-04-05 00:00:00

abstract：Background:Acupotomy, which involves the addition of a scalpel function to the conventional acupuncture treatment, has recently been applied as a conservative treatment method for lumbar disc herniation (LDH). This study investigated the effectiveness and safety of acupotomy, compared to manual acupuncture, for the tre...

journal_title：Journal of pain research

authors： Jeong JK,Kim E,Yoon KS,Jeon JH,Kim YI,Lee H,Kwon O,Jung SY,Lee JH,Yang C,Kang JH,Han CH

更新日期：2020-04-01 00:00:00

abstract：Purpose:To identify risk factors for pain after transarterial chemoembolization with drug-eluting beads (DEB-TACE) for hepatocellular carcinoma (HCC). Patients and Methods:In this retrospective study, a total of 118 consecutive patients who underwent DEB-TACE between June 2016 and May 2019 with post-TACE pain were inc...

journal_title：Journal of pain research

authors： Wang TC,Zhang ZS,Xiao YD

更新日期：2020-03-27 00:00:00

abstract：Background:Central post-stroke pain (CPSP) is refractory to pharmacotherapy (eg, NSAIDs, opioids, antidepressants, and anticonvulsants), and may require transcranial or deep brain stimulation. Case Presentation:A 67-year-old woman presented with severe paroxysmal cramp-like pain on the right side, including the head a...

journal_title：Journal of pain research

authors： Liu Q,Zhong Q,Tang G,Ye L

更新日期：2020-02-26 00:00:00

abstract：Background:G protein-gated inwardly rectifying potassium (GIRK) channels are involved in the regulation of neuronal excitability. Four GIRK subunits (GIRK1-4) are expressed in rat dorsal root ganglia (DRGs). Recently, we have characterized the expression of GIRK1 and -2, and both are downregulated in rat DRGs and spina...

journal_title：Journal of pain research

authors： Lyu C,Lyu GW,Mulder J,Martinez A,Shi TS

更新日期：2020-02-17 00:00:00

abstract：Objective:This study investigated psychological characteristics of patients with chronic complex regional pain syndrome (CRPS) and examined relationships between psychosocial factors and pain severity. Methods:In total, 76 patients with CRPS, 95 patients with other types of chronic pain, 171 healthy controls, and 66 p...

journal_title：Journal of pain research

authors： Park HY,Jang YE,Oh S,Lee PB

更新日期：2020-02-13 00:00:00

abstract：Purpose:To investigate the ameliorative effects of Vitellaria paradoxa (VP) nut extract for an anterior cruciate ligament transection with medial meniscectomy (ACLT+MMx)-induced osteoarthritis (OA) in high-fat diet (HFD)-induced obese rats. Methods:The rats were fed by HFD for 5 weeks before surgery-induced OA. Rats w...

journal_title：Journal of pain research

authors： Sudirman S,Chen CK,Long BT,Chang HW,Tsou D,Kong ZL

更新日期：2020-01-30 00:00:00

abstract：Background:With the increase in life expectancy seen throughout the world, the prevalence of degenerative spinal pathology and surgery to treat it has increased. Spinal surgery under general anesthesia leads to various problems and complications, especially in patients with numerous medical comorbidities or elderly pat...

journal_title：Journal of pain research

authors： Kang SY,Kashlan ON,Singh R,Rane R,Adsul NM,Jung SC,Yi J,Cho HS,Kim HS,Jang IT,Oh SH

更新日期：2020-01-21 00:00:00

abstract：Background and Aims:Plantar fasciitis (PF) is the leading cause of heel pain in adults. This study was designed to evaluate the effect of hyaluronic acid (HA) injection in reducing the symptoms of PF, compared with corticosteroid (CS) injection as a conventional treatment. Methods:In this triple-blind, randomized, cli...

journal_title：Journal of pain research

authors： Raeissadat SA,Nouri F,Darvish M,Esmaily H,Ghazihosseini P

更新日期：2020-01-14 00:00:00

abstract：Background:Cast immobilization is the primary treatment for children with forearm fractures. After emergency department (ED) discharge, some patients develop cast-related pain (CstRP) around the distal part of the upper extremity. We examined variables associated with ED revisits due to CstRP in children with forearm f...

journal_title：Journal of pain research

authors： Kvatinsky N,Carmiel R,Leiba R,Shavit I

更新日期：2020-01-08 00:00:00

abstract：Background:Femoral nerve block (FNB) has been considered as an excellent analgesic modality in total knee arthroplasty (TKA) pain control. However, relatively high concentration of ropivacaine could lead to quadriceps muscle weakness and increase the risk of postoperative falls. Objective:This double-blinded randomize...

journal_title：Journal of pain research

authors： Yang X,Kang W,Xiong W,Lu D,Zhou Z,Chen X,Zhou X,Feng X

更新日期：2019-12-17 00:00:00

abstract：Background:Many aspects of study conduct impact the observed effect size of treatment. Data were utilized from a recently published meta-analysis of randomized, double-blind, placebo-controlled, clinical trials performed for the United States Food and Drug Administration (FDA) approval of full mu-agonist opioids for th...

journal_title：Journal of pain research

authors： Meske DS,Vaughn BJ,Kopecky EA,Katz N

更新日期：2019-11-20 00:00:00