解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:INTRODUCTION:Declines in physical fitness can notably affect healthy aging of older adults. Multimodal exercise training regimen such as mind-body interventions (MBIs) has been reported to mitigate these aging-related declines of physical function. This meta-analytical review aimed at pooling the effects of MBIs on phy...
journal_title:Gerontology
pub_type: meta分析
doi:10.1159/000512675
更新日期:2021-01-27 00:00:00
abstract:OBJECTIVE:In Germany, there is an ongoing concern about the high prevalence of underweight on admission to health-care institutions. In order to assess possible sex-specific differences, the aim of this study is to provide valid figures about the prevalence and risk factors of underweight of men and women in German nur...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000512459
更新日期:2021-01-20 00:00:00
abstract:BACKGROUND:Cognitively stimulating activities contribute to the accumulation of cognitive reserve that is proposed to be instrumental for maintaining cognitive functioning in aging. Adopting a novel, more general conceptual perspective including models of vulnerability, we argue that cognitive reserve may modify the lo...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000501293
更新日期:2020-01-01 00:00:00
abstract::Period life expectancy is one of the most used summary indicators for the overall health of a population. Its levels and trends direct health policies, and researchers try to identify the determining risk factors to assess and forecast future developments. The use of period life expectancy is often based on the assump...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000500955
更新日期:2020-01-01 00:00:00
abstract::As populations age globally, the health of older adults is looming larger on the agendas of public health bodies. In particular, the priority is to ensure that older adults remain healthy, independent, and engaged in their communities. In other words, ensuring that increasing life spans are matched by increasing "heal...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000503141
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Even though poor lighting at nighttime is an important risk factor for falls (and most falls occur during the night), lighting interventions to improve nightly lighting from bed to bathroom are rarely evaluated for fall prevention. OBJECTIVE:We tested the hypothesis that an automated guiding light would red...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000504883
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Many falls in older adults occur during walking and result in lateral falls. The ability to perform a recovery step after balance perturbation determines whether a fall will occur. AIM:To investigate age-related changes in first recovery step kinematics and kinematic adaptations over a wide range of later...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000505649
更新日期:2020-01-01 00:00:00
abstract::Historically, family ties have been understood as the primary source of support for aging adults, and past empirical and theoretical work has highlighted the tendency of older adults to focus on close family. However, in line with demographic changes and historical increases in the diversity of social structures, frie...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000505547
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Due to declining birthrates and an increasing aging population, shortage of the caregiving labor force has become a global issue. Among various efforts toward the solution, introducing robotic products for assistance could provide an effective way to help older adults in their daily lives. As previous studie...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000507812
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Many studies have demonstrated an inverse relationship between gait performance and cognitive impairment. The main purposes of this study were: (1) to design and validate a complex gait test (CGT) in older people, (2) to analyze the effects of age and sex on CGT, and (3) to analyze the association between CG...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000508245
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Age-related functional decline elevates the risk of car accidents. Whether specific cognitive impairments and physical frailty increase the risk of car accidents is still unclarified. OBJECTIVE:This study examines the association between car accidents, frailty, and cognitive function, owing to an increase...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000508823
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:The identification of modifiable health span-promoting factors is a public health priority. OBJECTIVE:To explore the socio-environmental, lifestyle, behavioural, and psychological determinants of a clinical phenotypic measure of biological ageing in the Singapore Longitudinal Ageing Study (SLAS) cohort. ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000511211
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Thyroid hormones have significant effects on the cardiovascular systems. In general, hyperthyroidism is associated with an increased risk of dysrhythmias, while hypothyroidism may cause atherosclerosis. Recent large studies have sought to identify aging-associated changes in thyroid function and their releva...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000490911
更新日期:2019-01-01 00:00:00
abstract::Dysfunction associated with the aging process positions aging as a leading culprit for development of devastating diseases and mounting health-care costs. Many age-associated conditions for which aging increases risk are neurological disorders with no effective treatments, including Alzhei-mer's disease. As the propor...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000492573
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Perceived stress may be a modifiable risk factor for mild cognitive impairment (MCI) and ultimately dementia, but studies on this topic from low- and middle-income countries (LMICs) are lacking. OBJECTIVE:We assessed the association between perceived stress and MCI in six LMICs (China, Ghana, India, Mexico,...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000492177
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Studies have demonstrated that measures of lower quality of care and associated adverse health effects are more prevalent in for-profit nursing homes compared to not-for-profit facilities. However, these studies omit persons who receive care in the community setting, and exclusively focus on isolated clinica...
journal_title:Gerontology
pub_type: 杂志文章,多中心研究
doi:10.1159/000492029
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Myostatin has been proposed as a candidate biomarker for frailty and sarcopenia. However, the relationship of myostatin with these conditions remains inconclusive. OBJECTIVE:To determine the association of serum myostatin concentration with body composition, physical fitness, physical activity level, and fr...
journal_title:Gerontology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000494137
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Proxy decision-making may be flawed by inaccurate perceptions of risk. This may be particularly true when older adults are the targets of the decisions, given the pervasive negative stereotypes about older adults. METHODS:In study 1, individuals aged 18- to 87 years (as target persons) as wel...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000494352
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Due to aging, tissue regeneration gradually declines. Contemporary strategies to promote tissue-specific regeneration, in particular in elderly patients, often include synthetic material apt for implantation primarily aiming at upholding body functions and regaining appropriate anatomical and functional inte...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000494798
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Historically, older adults have been disproportionately affected by disasters. In particular, homebound adults are especially at risk. As one facet of bolstering community resilience, home health agencies have been tasked with improving their patients' disaster preparedness. However, home health practitioner...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000494971
更新日期:2019-01-01 00:00:00
abstract::Some authors have hypothesised that life expectancy at birth could reach 100 years in developed countries in the next decades. Using recent data for French women, it is shown that life expectancy changes from 1993 to 2016 are mainly linked to mortality rates of oldest women. In recent years, it happened that life expe...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000497179
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Lying on the floor for a long time after falls, regardless of whether an injury results, remains an unsolved health care problem. In order to develop efficient and acceptable fall detection and reaction approaches, it is relevant to improve the understanding of the circumstances and the characteristics of po...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000478092
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Mild-to-moderate chronic kidney disease (CKD G3a) is prevalent in older adults. Substantial evidence suggests that individuals with advanced CKD face a high risk for common geriatric conditions, like functional impairment and cognitive decline, whereas the relationships between mild-to-moderate CKD and funct...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000484140
更新日期:2018-01-01 00:00:00
abstract::Age differences in decision-making are of theoretical interest and have important practical implications, but relevant lines of work are distributed across multiple disciplines and often lack integration. The present review proposes an overarching conceptual framework with the aim of connecting disjointed aspects of t...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000485247
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Paratonia is a distinctive form of hypertonia, causing loss of functional mobility in early stages of dementia to severe high muscle tone and pain in the late stages. For assessing and evaluating therapeutic interventions, objective instruments are required. OBJECTIVE:Determine the psychometric properties o...
journal_title:Gerontology
pub_type: 杂志文章,多中心研究
doi:10.1159/000485462
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Older adults are stereotypically considered to be risk averse compared to younger age groups, although meta-analyses on age and the influence of gain/loss framing on risky choices have not found empirical evidence for age differences in risk-taking. OBJECTIVE:The current study extends the investigation of a...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000487636
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Falls are a major cause of morbidity among older people. Multifaceted interventions may be effective in preventing falls and related fractures. OBJECTIVE:To evaluate the cost-effectiveness alongside the REducing Falls with Orthoses and a Multifaceted podiatry intervention (REFORM) trial. METHODS:REFORM was...
journal_title:Gerontology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1159/000489171
更新日期:2018-01-01 00:00:00
abstract::The last 2 decades have brought an explosion of research, new products, and general attention to the problem of urinary urgency, and yet patients continue to be plagued by this symptom - especially the elderly. What is it? What does it mean? How can we guide patients successfully through this challenge? This paper pre...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000492330
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Orthostatic hypotension (OH) is common in older adults and associated with increased morbidity and mortality, loss of independence and high health-care costs. Standing up slowly is a recommended non-pharmacological intervention. However, the effectiveness of this advice has not been well studied. OBJECTIVES...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000450642
更新日期:2017-01-01 00:00:00
abstract::The Zika virus (ZIKV) outbreak in French Polynesia, in 2013, and in Brazil, in 2015, was correlated with neurological complications, which comprised, among others, congenital microcephaly and Guillain-Barré syndrome (GBS), which includes a group of acute autoimmune neuropathies generally reported after respiratory or ...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000453579
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:It is known from clinical practice and observational studies that elderly patients with a diagnosis of inflammatory rheumatic diseases (IRD) bear a significantly increased risk for cardiovascular diseases such as coronary artery disease (CAD) and heart failure. The molecular mechanism, however, is still not ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000471763
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Although foot pain has been linked to fall risk, contributions of pain severity, foot posture, or foot function are unclear. These factors were examined in a cohort of older adults. OBJECTIVE:The purpose of this study was to examine the associations of foot pain, severity of foot pain, and measures of foot ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000475710
更新日期:2017-01-01 00:00:00
abstract::Sarcopenia is a complex and multifactorial disease that includes a decrease in the number, structure and physiology of muscle fibers, and age-related muscle mass loss, and is associated with loss of strength, increased frailty, and increased risk for fractures and falls. Treatment options are suboptimal and consist of...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000479278
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Despite declines in cognitive abilities, older adults often perform comparable to younger adults in everyday tasks [J Am Geriatr Soc 1999;47:172-183]. Older adults may compensate for cognitive declines by using more efficient strategies. People often improve their efficiency by switching from an algorithmic ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000446277
更新日期:2016-01-01 00:00:00
abstract::Older adults often face challenges as they transition out of the acute care hospital, especially with regard to adhering to their medications. In this narrative review, we discuss medication adherence in older adults across the continuum of care, describing reasons for nonadherence, methods to assess adherence and too...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000363765
更新日期:2015-01-01 00:00:00
abstract::New neurons are continuously generated and added to neural circuits in the adult brain. However, increasing age imposes changes in neural progenitor cells and their microenvironment that lead to a reduction of neurogenesis. Age-related decreased production of new neurons in the neurogenic dentate gyrus has been associ...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000368575
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Future time perspective has been associated with subjective well-being, though depending on the line of research considered either an open-ended future time perspective or a limited future time perspective has been associated with high well-being. Most of this research however has conceptualized future time ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000368716
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Recruiting older adults, their family members and their home care workers as participants in research studies is particularly complicated. This might be due to medical or cognitive problems of the older adult as well as the high workload and shortage of time experienced by caregivers. The present study compa...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000366161
更新日期:2015-01-01 00:00:00
abstract::Older adults have surprisingly high levels of well-being, which has been referred to as a paradox in the past. Improved emotion regulation has been suggested to underlie these high levels of well-being. Later life is also a period with enhanced exposure to critical life events, and this comes with risks. During such t...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000371707
更新日期:2015-01-01 00:00:00
abstract::Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulat...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000371845
更新日期:2015-01-01 00:00:00