Abstract:
INTRODUCTION:Many falls in older adults occur during walking and result in lateral falls. The ability to perform a recovery step after balance perturbation determines whether a fall will occur. AIM:To investigate age-related changes in first recovery step kinematics and kinematic adaptations over a wide range of lateral perturbation magnitudes while walking. METHODS:Thirty-five old (78.5 ± 5 years) and 19 young adults (26.0 ± 0.8 years) walked at their preferred walking speed on a treadmill. While walking, the subjects were exposed to announced right/left perturbations in different phases of the gait cycle that were gradually increased in order to trigger a recovery stepping response. The subjects were instructed to react naturally and try to avoid falling. Kinematic analysis was performed to analyze the first recovery step parameters (e.g., step initiation, swing duration, step length, and the estimated distance of the center of mass from the base of support [dBoS]). RESULTS:Compared with younger adults, older adults displayed a significantly lower step threshold and at lower perturbation magnitudes during the experiment. Also, they showed slower compensatory step initiation, shorter step length, and dBoS with similar step recovery times. As the perturbation magnitudes increased, older adults showed very small, yet significant, decreases in the timing of the step response, and increased their step length. Younger adults did not show changes in the timing of stepping, with a tendency toward a significant increase in step length. CONCLUSIONS:First compensatory step performance is impaired in older adults. In terms of the dynamic approach, older adults were more flexible, i.e., less automatic, while younger adults displayed more automatic behavior.
journal_name
Gerontologyjournal_title
Gerontologyauthors
Nachmani H,Shani G,Shapiro A,Melzer Idoi
10.1159/000505649subject
Has Abstractpub_date
2020-01-01 00:00:00pages
362-370issue
4eissn
0304-324Xissn
1423-0003pii
000505649journal_volume
66pub_type
杂志文章相关文献
GERONTOLOGY文献大全abstract:BACKGROUND:Fall incidents and their negative outcomes represent a considerable problem in hospitals, especially in geriatric wards, and require implementation of strategies to prevent these undesirable events. For this reason, the College of Geriatrics, a body funded by the Belgian Government to set up quality improvem...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000224936
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:Due to an increase in the percentage of older people in industrialized countries there is an increasing demand for medical care for the elderly. With advancing age, a series of structural, architectural and compositional modifications take place in the vasculature. Therefore, we analyzed the influence of pat...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000080177
更新日期:2004-11-01 00:00:00
abstract::The activity of ceruloplasmin (CP) increased 3-fold in rat blood between 1 week and 20 months of age, but the difference in CP activity of adult and old rats was only 14%, which still is statistically significant (p less than 0.01). The increase in NaCl and KCl concentrations in vitro resulted in the same exponential ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213261
更新日期:1991-01-01 00:00:00
abstract::The eukaryotic stress response involves translational suppression of non-housekeeping proteins and the sequestration of unnecessary mRNA transcripts into stress granules (SGs). This process is dependent on mRNA-binding proteins (RBPs) that interact with capped mRNA transcripts through RNA recognition motifs, and exhib...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000354170
更新日期:2013-01-01 00:00:00
abstract:UNLABELLED:BACKGROUND; The link between experiencing difficulties in reading or understanding and non-compliance with drug treatment among seniors is not clearly established. OBJECTIVES:We measured the effect of both difficulties in reading, as well as difficulties in understanding prescription labelling, on non-compl...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000048924
更新日期:2002-01-01 00:00:00
abstract::Still's disease is very rare in elderly patients. We report a case of Still's disease in an elderly patient that had an atypical initial presentation. A 76-year-old woman developed unexplained chronic anemia and thrombocytosis. Three years later she had acute onset of high fever, arthritis, maculopapular rash, pleurit...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000102949
更新日期:2007-01-01 00:00:00
abstract::During the past decade, controversy has raged about the necessity of renal biopsy for the management of the idiopathic nephrotic syndrome. The debate has centered on whether a precise diagnosis is imperative for steroid treatment or whether such therapy can be given blindly. The above question has not been addressed i...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213514
更新日期:1993-01-01 00:00:00
abstract::The effects of ovine corticotropin releasing factor (o-CRF) on the secretions of ACTH, cortisol, dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S) were studied in the healthy young and elderly male individuals. o-CRF caused significant elevations of plasma ACTH, cortisol and DHEA concentrations...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212812
更新日期:1986-01-01 00:00:00
abstract::We examined the presenting features, clinical course and prognosis in relation to age in 121 patients with primary biliary cirrhosis (PBC) for a mean follow-up of 4.6 years. 35 patients (29%) were over age 65 years at presentation/detection. There was a higher proportion of patients asymptomatic of liver disease in th...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212701
更新日期:1985-01-01 00:00:00
abstract::Sera from 40 elderly individuals ranging in age from 60 to 94 years were tested for the presence of antibodies to varicella-zoster virus (VZV)-specific proteins. Sodium dodecylsulfate polyacrylamide gel electrophoresis analysis of lysates of VZV-infected BSC-1 cells labeled with either [35S]methionine or [3H]mannose a...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212962
更新日期:1988-01-01 00:00:00
abstract::Over the past decades, information about the characteristics of attractiveness has accumulated. We know about eight pillars of beauty, among them youthfulness, symmetry, hormone markers and body odor. But what is the biological function of these attractive signals? Is there one common function to be found in all eight...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000265559
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Hypoxia and aging determine on mammalian cells a stress response which implies modified production of oxidants, reactive oxygen species or reactive nitrogen species at the mitochondrial level, interfering with cell-signaling proteins and inducing mitochondrial damage, apoptosis occurrence and functional cons...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000299105
更新日期:2010-01-01 00:00:00
abstract::Both ageing and vitamin C (VC) deficiency result in immune defect. Since low serum and tissue levels of VC are found in the elderly, we have in a placebo-controlled study, tested the effect of VC supplements (500 mg/day i.m. for 1 month) on various immune parameters. Indeed, VC enhances the proliferative response of T...
journal_title:Gerontology
pub_type: 临床试验,杂志文章
doi:10.1159/000213131
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND:Thyroid hormones have significant effects on the cardiovascular systems. In general, hyperthyroidism is associated with an increased risk of dysrhythmias, while hypothyroidism may cause atherosclerosis. Recent large studies have sought to identify aging-associated changes in thyroid function and their releva...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000490911
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Recent studies have shown that vitamin D status may be relevant for physical and cognitive performance in the older population. This association may be of particular interest to older people at risk for cognitive impairment and functional decline. OBJECTIVE:The aim of this study was to determine the associa...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000355667
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The rate of lipogenesis and gene expression of lipogenic enzymes in white adipose tissue (WAT) of rats decreases with age. Previously, we showed the inverse relationship between serum leptin concentration and lipogenic enzymes activities in WAT of ageing rats. Based on those results, we postulated that lepti...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000187430
更新日期:2009-01-01 00:00:00
abstract::Paraneoplastic symptoms, caused by a malignancy, but not directly related to invasion by the tumor or its metastases, are the result of a wide variety of tumor-derived biologic mediators like hormones, peptides, antibodies, cytotoxic lymphocytes, autocrine and paracrine mediators. Systemic inflammatory rheumatic disea...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000314634
更新日期:2011-01-01 00:00:00
abstract::A prospective study of post-operative morbidity in 258 elderly general surgical patients is reported. In 35% of patients no post-operative complications developed. Respiratory, wound and cardiac complications were the leading types of post-operative morbidity encountered, occurring in 39.5, 16.3, and 12.4% of patients...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213125
更新日期:1983-01-01 00:00:00
abstract::Taurine (TAU) is thought to be a neuromodulator or an inhibitory neurotransmitter in the mammalian brain. In the periphery, TAU is involved in a wide spectrum of physiological functions. One of the most important putative physiological function of TAU is the modulation of cardiovascular activity including blood pressu...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213171
更新日期:1990-01-01 00:00:00
abstract::To determine the influence of age, disease and other factors on anthropometric indices in elderly subjects aged 70 years and above, body mass index (BMI), arm muscle circumference (AMC), corrected arm muscle area (CAMA), fat-free mass (FFM) and total body fat (TBF) were determined in a random sample of 990 Chinese men...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213679
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE AND BACKGROUND:The aim of the present article is to discuss the potential of gene therapy for thymic hormones as a novel therapeutic strategy to treat dyshomeostatic states associated with athymia, as Di George syndrome, or hypothymic conditions like those associated with AIDS, chronic stress or aging. First ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000065258
更新日期:2002-09-01 00:00:00
abstract::Aging is associated with a decline in renal concentrating ability in response to dehydration-induced arginine vasopressin (AVP) release. To examine target tissue sensitivity, cortical collecting tubules (CCT) were individually microdissected from young (3 months), middle-aged (2-3 years) and old (4-5.5 years) rabbits ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000213348
更新日期:1992-01-01 00:00:00
abstract::Differences between women and men in terms of gender gaps at late stages of their lives are the focus of this mini-review. We approach the matter by taking up the position of complex yet promising standpoints, the bio-psycho-social perspective on the one hand and approaches of developmental psychology on the other. Li...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000323154
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:compared with other vertebrate taxa, mammals possess a very limited capacity for appendage regeneration. The antlers of deer are an exception in that they are periodically lost and fully regenerated throughout the life of an individual. OBJECTIVE:in this paper we compare certain aspects of antler regenerati...
journal_title:Gerontology
pub_type: 杂志文章,评审
doi:10.1159/000300565
更新日期:2011-01-01 00:00:00
abstract::The effects of long-term cigarette smoking on regional cerebral blood flow (rCBF) were studied in 67 normal male volunteers. All subjects were healthy volunteers without any past history of cerebral and pulmonary disease. rCBF decreased significantly with advancing age. Although there was no significant difference in ...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212953
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:Wheelchairs are frequently prescribed for residents with mobility impairments in long-term care. Many residents receive poorly fitting wheelchairs, compromising functional independence and mobility, and contributing to subsequent health issues such as pressure ulcers. The extent of this problem and the facto...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000334819
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Although cross-sectional studies have demonstrated associations between visual contrast sensitivity and cognitive test performance, it remains unclear whether peripheral visual or perceptual factors explain the association. OBJECTIVE:We aimed at determining whether reducing static contrast of the study stim...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000090958
更新日期:2006-01-01 00:00:00
abstract::Aging researchers have long been interested in understanding individuals' subjective perceptions of their own memory functioning. Previous research has shown that subjective memory ratings are partly based on memory performance but also reflect the influence of other factors, such as depressive symptoms. The aim of th...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000369010
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:Creutzfeldt-Jakob disease (CJD) is not only a disorder of the central nervous system but also affects the skeletal muscle. Subclinical skeletal muscle involvement, manifesting as hyper-creatine-kinase (CK)-emia, is rare. CASE REPORT:The patient, a 60-year-old male, developed progressive dementia, accompanie...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000093659
更新日期:2006-01-01 00:00:00
abstract::The spectrum of aldimine cross-link bonds of skin collagen is dependent on the localization of the examined material. In correlation to this, there is no synchronous behaviour of cross-linkage in the aging process. The age-dependent decrease of HLNL and the increase of DHLNL in the collagen of tail tendon is only unsu...
journal_title:Gerontology
pub_type: 杂志文章
doi:10.1159/000212268
更新日期:1978-01-01 00:00:00