Aging and Decision-Making: A Conceptual Framework for Future Research - A Mini-Review.

abstract：BACKGROUND:It is known that growth factors play a role in ageing and atherogenesis, and insulin develops mitogenic activity in vitro. OBJECTIVES:This study focuses on the pathway by which insulin induces proliferation and mobility in vascular smooth muscle cells (SMCs) compared with that of insulin-like growth factor-...

journal_title：Gerontology

authors： Ruiz-Torres A,Lozano R,Melón J,Carraro R

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Constipation and lower urinary tract symptoms (LUTS) very frequently occur in the elderly, and several reports have suggested that dysfunction in either one of these systems may affect the other. Most studies correlating rectal and bladder dysfunction, however, have been carried out in children or young wome...

journal_title：Gerontology

authors： Charach G,Greenstein A,Rabinovich P,Groskopf I,Weintraub M

更新日期：2001-03-01 00:00:00

abstract：:The effects of long-term cigarette smoking on regional cerebral blood flow (rCBF) were studied in 67 normal male volunteers. All subjects were healthy volunteers without any past history of cerebral and pulmonary disease. rCBF decreased significantly with advancing age. Although there was no significant difference in ...

journal_title：Gerontology

authors： Yamashita K,Kobayashi S,Yamaguchi S,Kitani M,Tsunematsu T

更新日期：1988-01-01 00:00:00

abstract：:Neuropsychological research contributes to a better understanding of cognitive mechanisms involved in making advantageous decisions, which is important for everyday life. Using laboratory gambling tasks, it has been demonstrated that both structural and functional brain changes can result in disadvantageous decision-m...

journal_title：Gerontology

authors： Brand M,Markowitsch HJ

更新日期：2010-01-01 00:00:00

abstract：:The effect of ageing on the threshold firing rate of motor units from the first dorsal interosseous muscle was investigated. Two groups of 9 healthy male subjects between the ages of 20-29 and 60-69 years took part in the study. The threshold firing rate of motor units in young subjects showed close agreement with pre...

journal_title：Gerontology

authors： Newton JP,Yemm R,McDonagh MJ

更新日期：1988-01-01 00:00:00

abstract：:The purpose of this study was to examine the effects of a multifactorial memory training program designed for normal older adults. The multifactorial program involved the training of three components that are critical to memory functioning: recoding operations, attentional functions and relaxation. Two controls groups...

journal_title：Gerontology

authors： Stigsdotter A,Bäckman L

更新日期：1989-01-01 00:00:00

abstract：:The effects of ageing and of 6 months of Hydergine treatment on lipofuscin deposition within the cytoplasma of pyramidal neurons of rat prefrontal cortex, hippocampus (fields CA1 and CA3) and of Purkinje neurons were assessed microfluorimetrically. No lipofuscin autofluorescence was detected in the nerve cell populati...

journal_title：Gerontology

authors： Amenta D,Ferrante F,Franch F,Amenta F

更新日期：1988-01-01 00:00:00

abstract：:The relation between carotid blood flow measured by Doppler spectrum analysis and brain atrophy on computed tomography (CT) was studied in 22 subjects with multiple lacunar cerebral infarctions. The subjects were divided into two groups, 7 patients with multi-infarct dementia (MID) (mean age 73 years) and 15 nondement...

journal_title：Gerontology

authors： Yamashita K,Kobayashi S,Yamaguchi S,Kitani M,Okada K,Fujihara S,Shimode K,Tsunematsu T

更新日期：1989-01-01 00:00:00

abstract：:Mitochondrial abnormality in the skeletal muscles of 13 patients with myotonic dystrophy was analyzed by both histochemical and molecular biologic methods. Nine of 13 patients had ragged-red fibers (50 +/- 116 per 10,000 muscle fibers, mean +/- SD), and 10 patients had cytochrome c oxidase-negative fibers (41 +/- 90 p...

journal_title：Gerontology

authors： Sahashi K,Tanaka M,Tashiro M,Ohno K,Ibi T,Takahashi A,Ozawa T

更新日期：1992-01-01 00:00:00

abstract：:To evaluate the requirement for provocative cystometry in urodynamic investigation in the elderly with urinary incontinence, 100 consecutive patients, who were referred on the basis of defined clinical criteria, were first studied by supine cystometry followed by provocative tests where necessary. The most satisfactor...

journal_title：Gerontology

authors： Eastwood HD

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Historically, older adults have been disproportionately affected by disasters. In particular, homebound adults are especially at risk. As one facet of bolstering community resilience, home health agencies have been tasked with improving their patients' disaster preparedness. However, home health practitioner...

journal_title：Gerontology

authors： Wyte-Lake T,Claver M,Tubbesing S,Davis D,Dobalian A

更新日期：2019-01-01 00:00:00

abstract：:The last 2 decades have brought an explosion of research, new products, and general attention to the problem of urinary urgency, and yet patients continue to be plagued by this symptom - especially the elderly. What is it? What does it mean? How can we guide patients successfully through this challenge? This paper pre...

journal_title：Gerontology

authors： Potts JM,Payne CK

更新日期：2018-01-01 00:00:00

abstract：:The effect of age on the compositional analysis of human Descemet's membrane was examined. Membranes were obtained from human corneas ranging from 0.5 to 95 years and purified by sodium dodecyl sulfate (SDS) extraction. Substantial age-related changes were obtained in the amino acid compositions of the SDS-insoluble b...

journal_title：Gerontology

authors： Freeman IL,Vergnes JP,Brown SI

更新日期：1980-01-01 00:00:00

abstract：:Age-related changes of muscle fiber and collagen content of the diaphragm (DIA) and rectus abdominis (RA) muscles were examined in rats aged 1, 4, 8 and 18 months. The cross-sectional areas of all muscle fiber types (I, IIa, IIb) and the amount of collagen in both DIA and RA increased up to the age of 8 months after w...

journal_title：Gerontology

authors： Rodrigues CJ,Rodrigues Júnior AJ,Bohm GM

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Although white matter changes visible with MRI are generally considered to result from ischemia, it has become clear that these changes also appear in patients with Alzheimer's disease (AD). However, their significance in AD is unknown. OBJECTIVE:We evaluated the clinical significance of white matter change...

journal_title：Gerontology

authors： Kono I,Mori S,Nakajima K,Nakagawa M,Watanabe Y,Kizu O,Yamada K,Sakai Y

更新日期：2004-07-01 00:00:00

abstract：:Glutamine synthetase (GS) activity was measured in whole brain, different brain areas, liver and heart of 23- to 26-month-old rats, and then compared to matched animals of 3 months. A significant increase of GS activity was found in whole brain (25%) of old rats, as well as in all brain areas studied, but particularly...

journal_title：Gerontology

authors： Cao Danh H,Strolin Benedetti M,Dostert P

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Myostatin has been proposed as a candidate biomarker for frailty and sarcopenia. However, the relationship of myostatin with these conditions remains inconclusive. OBJECTIVE:To determine the association of serum myostatin concentration with body composition, physical fitness, physical activity level, and fr...

journal_title：Gerontology

authors： Arrieta H,Hervás G,Rezola-Pardo C,Ruiz-Litago F,Iturburu M,Yanguas JJ,Gil SM,Rodriguez-Larrad A,Irazusta J

更新日期：2019-01-01 00:00:00

abstract：:Adult stem cells in mammalian organs play pivotal roles in the maintenance and repair of these organs throughout the life of the adult and maintain the proper homeostasis of a tissue or organ. Among the adult stem cells described to date, mesenchymal stem cells (MSCs) are highlighted for clinical applications because ...

journal_title：Gerontology

authors： Yu KR,Kang KS

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:Creutzfeldt-Jakob disease (CJD) is not only a disorder of the central nervous system but also affects the skeletal muscle. Subclinical skeletal muscle involvement, manifesting as hyper-creatine-kinase (CK)-emia, is rare. CASE REPORT:The patient, a 60-year-old male, developed progressive dementia, accompanie...

journal_title：Gerontology

authors： Finsterer J,Gelpi E

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Research on the relationship between vestibular function and falls in older people is sparse. The perception of the postural vertical (PPV) provides an indicator measure of vestibular (otolith) function in the absence of visual input and diminished somatosensory feedback. OBJECTIVE:This study examined wheth...

journal_title：Gerontology

authors： Menant JC,St George RJ,Fitzpatrick RC,Lord SR

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The results of the very few histochemical studies that have been performed so far on the lectin-binding profile of normal human epidermis are mostly controversial; thus, the carbohydrate residue composition of the cell surface in the latter still remains in dispute and the possible alterations in the epiderm...

journal_title：Gerontology

authors： Georgiou S,Pasmatzi E,Monastirli A,Sakkis T,Alachioti S,Tsambaos D

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Understanding comorbidity prevalence and the effects of comorbidities in older veterans with lower extremity amputations may aid in assessing patient outcomes, resource use, and facility-level quality of care. OBJECTIVES:To determine the degree to which adding outpatient to inpatient administrative data sou...

journal_title：Gerontology

authors： Kurichi JE,Stineman MG,Kwong PL,Bates BE,Reker DM

更新日期：2007-01-01 00:00:00

abstract：:Lymphopenia is a common finding in old people admitted to medical and psychiatric wards. We describe a pilot study of the clinical associations, and prognostic significance of lymphopenia in elderly persons admitted to acute medical and psychiatric wards. Consecutive patients admitted to acute medical and psychiatric ...

journal_title：Gerontology

authors： Dennis MS,Nicolson A,Lehmann AB,Junaid O,Byrne EJ,Hopkinson N

更新日期：1998-01-01 00:00:00

abstract：:We performed 24-hour ambulatory electrocardiographic (Holter) examinations in 50 retired hospital workers (30 men, 20 women), aged 58-85 years (mean age +/- SD: 65.9 +/- 4.6 years), with a normal clinical history, physical examination and baseline ECG. There was a significant difference between daytime and nocturnal m...

journal_title：Gerontology

authors： Ribera JM,Cruz AJ,Zamorano JL,Pérez-Casar F

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Perceived stress may be a modifiable risk factor for mild cognitive impairment (MCI) and ultimately dementia, but studies on this topic from low- and middle-income countries (LMICs) are lacking. OBJECTIVE:We assessed the association between perceived stress and MCI in six LMICs (China, Ghana, India, Mexico,...

journal_title：Gerontology

authors： Koyanagi A,Oh H,Vancampfort D,Carvalho AF,Veronese N,Stubbs B,Lara E

更新日期：2019-01-01 00:00:00

abstract：:Protein malnutrition is associated with a decreased febrile and acute phase response to infection and increased mortality. To elucidate a cause for this poor response, we assessed the effect of chronic protein malnutrition on monocyte production of the pyrogens interleukin-1 (IL-1) and tumor necrosis factor (TNF). Thi...

journal_title：Gerontology

authors： Bradley SF,Vibhagool A,Fabrick S,Terpenning MS,Kauffman CA

更新日期：1990-01-01 00:00:00

abstract：:In mammals, aging is often viewed as a progressive decline in physiological competence with a corresponding inability to adapt to stressful stimulation. Several current theories of aging have implicated the sympathetic nervous system in many of the metabolic, cardiovascular and behavior changes which attend advancing ...

journal_title：Gerontology

authors： McCarty R

更新日期：1986-01-01 00:00:00

abstract：:Creatine phosphokinase (CPK) has been shown to provide the initial ATP for muscle contraction. The effect of wheel running on CPK levels was compared in hindleg and cardiac muscles of young, intermediate-age and old outbred CW-1 and inbred C57BL mice. Short-term (5 weeks) and long-term (over 12 months) regimens were u...

journal_title：Gerontology

authors： Steinhagen-Thiessen E,Reznick AZ

更新日期：1987-01-01 00:00:00

abstract：:For logarithmically growing cultures of the human diploid cell lines WI-38 and WI-26, there is an exponential increase in the fraction of cells not incorporating [3H]dT under conditions of continuous labelling. Thymidine uptake, phosphorylation and incorporation into DNA can be correlated with cell proliferation. In a...

journal_title：Gerontology

authors： Cristofalo VJ

更新日期：1976-01-01 00:00:00

abstract：:Cell surface of chick fibroblasts were labelled by a short treatment with 125I in presence of lactoperoxidase. A glycoprotein (220,000 molec. wt) was iodinated and was present in a more exposed position or in greater amounts at the surface of old phase III cells compared to young phase II cells. The findings extend ou...

journal_title：Gerontology

authors： Courtois Y,Hughes RC

更新日期：1976-01-01 00:00:00