abstract：Importance:Knowledge of the incidence and progression of diabetic retinopathy (DR) after gastric bypass surgery (GBP) in patients with obesity and diabetes could guide the management of these patients. Objective:To investigate the incidence of diabetic ocular complications in patients with type 2 diabetes after GBP co...

journal_title：JAMA ophthalmology

authors： Åkerblom H,Franzén S,Zhou C,Morén Å,Ottosson J,Sundbom M,Eliasson B,Svensson AM,Granstam E

更新日期：2021-01-14 00:00:00

abstract：Importance:The coronavirus disease 2019 pandemic illustrates the increasingly important role of telemedicine as a method of clinician-patient interaction. However, electronic applications (apps) for the testing of ophthalmology vital signs, such as visual acuity, can be published and used without any verification of ac...

journal_title：JAMA ophthalmology

authors： Steren BJ,Young B,Chow J

更新日期：2021-01-14 00:00:00

abstract：Importance:Many ophthalmology appointments have been converted to telemedicine assessments. The use of a printed vision chart for ophthalmology telemedicine appointments that can be used by people who are excluded from digital testing has yet to be validated. Objectives:To evaluate the repeatability of visual acuity m...

journal_title：JAMA ophthalmology

authors： Crossland MD,Dekker TM,Hancox J,Lisi M,Wemyss TA,Thomas PBM

更新日期：2021-01-07 00:00:00

abstract：Importance:Glaucoma-related adverse events constitute serious complications of cataract removal in infancy, yet long-term data on incidence and visual outcome remain lacking. Objective:To identify and characterize incident cases of glaucoma and glaucoma-related adverse events (glaucoma + glaucoma suspect) among childr...

journal_title：JAMA ophthalmology

authors： Freedman SF,Beck AD,Nizam A,Vanderveen DK,Plager DA,Morrison DG,Drews-Botsch CD,Lambert SR,Infant Aphakia Treatment Study Group.

更新日期：2020-12-17 00:00:00

abstract：Importance:Coronavirus disease 2019 (COVID-19) has been recognized as a pandemic by the World Health Organization. Whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can also infect tissues besides the respiratory system, such as the ocular tissues, remains unclear. Objective:To determine whether SAR...

journal_title：JAMA ophthalmology

authors： Yan Y,Diao B,Liu Y,Zhang W,Wang G,Chen X

更新日期：2020-10-08 00:00:00

abstract：Importance:Ocular manifestations and outcomes in children with confirmed coronavirus disease 2019 (COVID-19), relevant affecting factors, and differences in ocular disease between children and adults have yet to be fully understood. Objective:To investigate ocular manifestations and clinical characteristics of childre...

journal_title：JAMA ophthalmology

authors： Ma N,Li P,Wang X,Yu Y,Tan X,Chen P,Li S,Jiang F

更新日期：2020-10-01 00:00:00

abstract：Importance:Because studies have suggested that atropine might slow the progression of myopia in children, randomized clinical trials are warranted to understand this potential causal relationship. Objective:To evaluate the efficacy and safety of atropine, 0.01%, eyedrops on slowing myopia progression and axial elongat...

journal_title：JAMA ophthalmology

authors： Wei S,Li SM,An W,Du J,Liang X,Sun Y,Zhang D,Tian J,Wang N

更新日期：2020-10-01 00:00:00

abstract：Importance:The 2-year efficacy and safety of combination therapy of ranibizumab administered together with verteporfin photodynamic therapy (vPDT) compared with ranibizumab monotherapy in participants with polypoidal choroidal vasculopathy (PCV) are unclear. Objective:To compare treatment outcomes of ranibizumab, 0.5 ...

journal_title：JAMA ophthalmology

authors： Lim TH,Lai TYY,Takahashi K,Wong TY,Chen LJ,Ruamviboonsuk P,Tan CS,Lee WK,Cheung CMG,Ngah NF,Patalauskaite R,Margaron P,Koh A,EVEREST II Study Group.

更新日期：2020-09-01 00:00:00

abstract：Importance:The ocular surface is continuously exposed to the environment. Although studies have focused on associations between outdoor environmental conditions and dry eye, information on associations between the indoor environment and dry eye is lacking. Objective:To determine associations between the indoor environ...

journal_title：JAMA ophthalmology

authors： Huang A,Janecki J,Galor A,Rock S,Menendez D,Hackam AS,Jeng BH,Kumar N

更新日期：2020-08-01 00:00:00

abstract：Importance:Some eyes with neovascular age-related macular degeneration (AMD) have persistent exudation despite frequent intravitreal anti-vascular endothelial growth factor (VEGF) injections. Adjuvant therapies that further reduce edema may improve vision outcomes. Objective:To compare the short-term effect of topical...

journal_title：JAMA ophthalmology

authors： Hsu J,Patel SN,Wolfe JD,Shah CP,Chen E,Jenkins TL,Wibbelsman TD,Obeid A,Mikhail M,Garg SJ,Ho AC,Chiang A,Spirn MJ,Vander JF

更新日期：2020-05-01 00:00:00

abstract：Importance:Visual impairment and visual disorders often co-occur with other chronic conditions. Understanding patterns of multimorbidity is important for reducing health care use and improving health outcomes. Objective:To identify chronic condition patterns and their association with visual impairment and health care...

journal_title：JAMA ophthalmology

authors： Zheng DD,Christ SL,Lam BL,Feaster DJ,McCollister K,Lee DJ

更新日期：2020-04-01 00:00:00

abstract：Importance:Preservation of peripheral visual field (VF) is considered an advantage for anti-vascular endothelial growth factor agents compared with panretinal photocoagulation (PRP) for treatment of proliferative diabetic retinopathy. Long-term data on VF are important when considering either treatment approach. Objec...

journal_title：JAMA ophthalmology

authors： Maguire MG,Liu D,Glassman AR,Jampol LM,Johnson CA,Baker CW,Bressler NM,Gardner TW,Pieramici D,Stockdale CR,Sun JK,DRCR Retina Network.

更新日期：2020-03-01 00:00:00

abstract：Importance:Anti-vascular endothelial growth factor (anti-VEGF) is a breakthrough treatment for wet age-related macular degeneration (wAMD), the most common cause of blindness in western countries. Anti-VEGF treatment prevents vision loss and has been shown to produce vision gains lasting as long as 5 years. Although th...

journal_title：JAMA ophthalmology

authors： Mulligan K,Seabury SA,Dugel PU,Blim JF,Goldman DP,Humayun MS

更新日期：2019-11-14 00:00:00

abstract：Importance:To prevent blindness, repeated infant eye examinations are performed to detect severe retinopathy of prematurity (ROP), yet only a small fraction of those screened need treatment. Early individual risk stratification would improve screening timing and efficiency and potentially reduce the risk of blindness. ...

journal_title：JAMA ophthalmology

authors： Pivodic A,Hård AL,Löfqvist C,Smith LEH,Wu C,Bründer MC,Lagrèze WA,Stahl A,Holmström G,Albertsson-Wikland K,Johansson H,Nilsson S,Hellström A

更新日期：2019-11-07 00:00:00

abstract：Importance:The comparative clinical effectiveness of ranibizumab, aflibercept, and bevacizumab for the management of macular edema due to central retinal vein occlusion (CRVO) is unclear. Objective:To determine whether intravitreal aflibercept or bevacizumab compared with ranibizumab results in a noninferior mean chan...

journal_title：JAMA ophthalmology

authors： Hykin P,Prevost AT,Vasconcelos JC,Murphy C,Kelly J,Ramu J,Hounsome B,Yang Y,Harding SP,Lotery A,Chakravarthy U,Sivaprasad S,LEAVO Study Group.

更新日期：2019-08-29 00:00:00

abstract：Importance:Given the estimates of increasing prevalence of myopia, especially in Asia, it is important to determine the current prevalence of myopia among populations of schoolchildren in Japan. Objective:To investigate the current prevalence rate of myopia and the association between environmental factors and myopia ...

journal_title：JAMA ophthalmology

authors： Yotsukura E,Torii H,Inokuchi M,Tokumura M,Uchino M,Nakamura K,Hyodo M,Mori K,Jiang X,Ikeda SI,Kondo S,Negishi K,Kurihara T,Tsubota K

更新日期：2019-08-15 00:00:00

abstract：Importance:Although almost equal numbers of male and female medical students enter into ophthalmology residency programs, whether they have similar surgical experiences during training is unclear. Objective:To determine differences for cataract surgery and total procedural volume between male and female residents duri...

journal_title：JAMA ophthalmology

authors： Gong D,Winn BJ,Beal CJ,Blomquist PH,Chen RW,Culican SM,Dagi Glass LR,Domeracki GF,Goshe JM,Jones JK,Khouri AS,Legault GL,Martin TJ,Mitchell KT,Naseri A,Oetting TA,Olson JH,Pettey JH,Reinoso MA,Reynolds AL,Siatkows

更新日期：2019-07-18 00:00:00

abstract：Importance:Contemporary data on use of eye care by US adults are critical, as the prevalence of age-related eye disease and vision impairment are projected to increase in the coming decades. Objectives:To provide nationally representative estimates on self-reported use of eye care by adults aged 50 to 80 years, and to...

journal_title：JAMA ophthalmology

authors： Ehrlich JR,Ndukwe T,Solway E,Woodward MA,Singer DC,Newman-Casey PA,Kirch M,Delott LB,Kullgren JT,Stagg BC,Musch DC,Malani PN

更新日期：2019-06-20 00:00:00

abstract：Importance:The frequency of anti-vascular endothelial growth factor (VEGF) injections has grown exponentially with the introduction of bevacizumab, ranibizumab, and most recently aflibercept. The cost associated with these medications has garnered significant national attention, warranting a granular analysis of their ...

journal_title：JAMA ophthalmology

authors： Berkowitz ST,Sternberg P Jr,Feng X,Chen Q,Patel S

更新日期：2019-06-20 00:00:00

abstract：Importance:The US Food and Drug Administration's medical device regulatory pathway was initially conceived with hardware devices in mind. The emerging market for ophthalmic digital devices necessitates an evolution of this paradigm. Objectives:To facilitate innovation in ophthalmic digital health with attention to saf...

journal_title：JAMA ophthalmology

authors： Bodnar ZM,Schuchard R,Myung D,Tarver ME,Blumenkranz MS,Afshari NA,Humayun MS,Morse C,Nischal K,Repka MX,Sprunger D,Trese M,Eydelman MB

更新日期：2019-06-06 00:00:00

abstract：Importance:A precise phenotypic characterization of retinal dystrophies is needed for disease modeling as a basis for future therapeutic interventions. Objective:To compare genotype, phenotype, and structural changes in patients with rod-cone dystrophy (RCD) associated with mutations in PDE6A or PDE6B. Design, Settin...

journal_title：JAMA ophthalmology

authors： Khateb S,Nassisi M,Bujakowska KM,Méjécase C,Condroyer C,Antonio A,Foussard M,Démontant V,Mohand-Saïd S,Sahel JA,Zeitz C,Audo I

更新日期：2019-06-01 00:00:00

abstract：Importance:The Argus II Retinal Prosthesis System is indicated for patients with vision loss due to severe to profound outer retinal degeneration, a group with few treatment options. Objectives:To collect postapproval safety and visual function data for the Argus II. Design, Setting, and Participants:Multicenter, pos...

journal_title：JAMA ophthalmology

authors： Schaffrath K,Schellhase H,Walter P,Augustin A,Chizzolini M,Kirchhof B,Grisanti S,Wiedemann P,Szurman P,Richard G,Greenberg RJ,Dorn JD,Parmeggiani F,Rizzo S

更新日期：2019-05-30 00:00:00

abstract：Importance:Mutations in the myocilin (MYOC) gene are the most common molecularly defined cause of primary open-angle glaucoma that typically occurs in patients with high intraocular pressures (IOP). One MYOC mutation, p.Gln368Ter, has been associated with as many as 1.6% of primary open-angle glaucoma cases that had a ...

journal_title：JAMA ophthalmology

authors： Alward WLM,van der Heide C,Khanna CL,Roos BR,Sivaprasad S,Kam J,Ritch R,Lotery A,Igo RP Jr,Cooke Bailey JN,Stone EM,Scheetz TE,Kwon YH,Pasquale LR,Wiggs JL,Fingert JH,NEIGHBORHOOD Consortium.

更新日期：2019-05-01 00:00:00

abstract：Importance:Both primary and secondary forms of childhood glaucoma have many distinct causative mechanisms, and in many cases a cause is not immediately clear. The broad phenotypic spectrum of secondary glaucoma, particularly in individuals with variants in FOXC1 or PITX2 genes associated with Axenfeld-Rieger syndrome, ...

journal_title：JAMA ophthalmology

authors： Siggs OM,Souzeau E,Pasutto F,Dubowsky A,Smith JEH,Taranath D,Pater J,Rait JL,Narita A,Mauri L,Del Longo A,Reis A,Chappell A,Kearns LS,Staffieri SE,Elder JE,Ruddle JB,Hewitt AW,Burdon KP,Mackey DA,Craig JE

更新日期：2019-04-01 00:00:00

abstract：Importance:Certain features of the lamina cribrosa may be associated with increased risk of glaucoma progression. Objectives:To compare the rates of retinal nerve fiber layer (RNFL) thinning in patients with open-angle glaucoma with or without lamina cribrosa (LC) defects and to evaluate factors associated with the ra...

journal_title：JAMA ophthalmology

authors： Moghimi S,Zangwill LM,Manalastas PIC,Suh MH,Penteado RC,Hou H,Hasenstab K,Ghahari E,Bowd C,Weinreb RN

更新日期：2019-04-01 00:00:00

abstract：Importance:Most premature infants will not develop retinopathy of prematurity (ROP) of clinical relevance, yet screening evaluations often continue beyond hospital discharge, even for those infants without ROP. Objectives:To identify the characteristics of infants at low risk for ROP, for whom further postdischarge sc...

journal_title：JAMA ophthalmology

authors： Wade KC,Ying GS,Baumritter A,Gong A,Kemper AR,Quinn GE,e-ROP Cooperative Group.

更新日期：2019-02-01 00:00:00

abstract：Importance:Vitreoretinal lymphoma is a diagnostic challenge and the pathophysiology is still unclear. Objective:To describe an imaging finding seen on optical coherence tomography (OCT) of patients with vitreoretinal lymphoma. Design, Setting, and Participants:This case series study was a retrospective medical record...

journal_title：JAMA ophthalmology

authors： Deák GG,Goldstein DA,Zhou M,Fawzi AA,Jampol LM

更新日期：2019-02-01 00:00:00

abstract：Importance:Given the rarity of posterior uveal melanoma in patients younger than 21 years, reporting clinical experience in this area has relevance. Objective:To describe the baseline clinical features, treatment, and clinical course of a group of patients younger than 21 years who have primary posterior uveal melanom...

journal_title：JAMA ophthalmology

authors： Fry MV,Augsburger JJ,Corrêa ZM

更新日期：2019-01-01 00:00:00

abstract：Importance:Early detection of choroidal melanoma at a small tumor size is emphasized in the literature. However, there is little published information on the specific risks of plaque-irradiated small choroidal melanoma on visual acuity and metastasis. Objective:To analyze outcomes of plaque radiotherapy for small chor...

journal_title：JAMA ophthalmology

authors： Shields CL,Sioufi K,Srinivasan A,Di Nicola M,Masoomian B,Barna LE,Bekerman VP,Say EAT,Mashayekhi A,Emrich J,Komarnicky L,Shields JA

更新日期：2018-12-01 00:00:00

abstract：Importance:Adding a laser-induced chorioretinal anastomosis (L-CRA) to current treatments for central retinal vein occlusion (CRVO) may improve outcomes and lessen therapy burdens. Objective:To determine the 2-year efficacy of intravitreal ranibizumab with an L-CRA vs ranibizumab alone for patients with macular edema ...

journal_title：JAMA ophthalmology

authors： McAllister IL,Smithies LA,Chen FK,Mackey DA,Sanfilippo PG

更新日期：2018-12-01 00:00:00

abstract：Importance:Medical and surgical interventions for glaucoma are effective only if they are affordable to patients. Little is known about how affordable glaucoma interventions are in developing and developed countries. Objective:To compare the prices of topical glaucoma medications, laser trabeculoplasty, and trabeculec...

journal_title：JAMA ophthalmology

authors： Zhao PY,Rahmathullah R,Stagg BC,Almobarak F,Edward DP,Robin AL,Stein JD

更新日期：2018-11-01 00:00:00

abstract：Importance:To our knowledge, a set of well-defined diagnostic criteria is not yet developed for the diagnosis of Vogt-Koyanagi-Harada (VKH) disease. Objective:To develop and evaluate a set of diagnostic criteria for VKH disease using data from Chinese patients. Design, Setting, and Participants:This case-control stud...

journal_title：JAMA ophthalmology

authors： Yang P,Zhong Y,Du L,Chi W,Chen L,Zhang R,Zhang M,Wang H,Lu H,Yang L,Zhuang W,Yang Y,Xing L,Feng L,Jiang Z,Zhang X,Wang Y,Zhong H,Jiang L,Zhao C,Li F,Cao S,Liu X,Chen X,Shi Y,Zhao W,Kijlstra A

更新日期：2018-09-01 00:00:00

abstract：Importance:Visual acuity (VA) outcomes differ considerably among patients with neovascular age-related macular degeneration (nAMD) treated with anti-vascular endothelial growth factor (VEGF) drugs. Identification of pharmacogenetic associations may help clinicians understand the mechanisms underlying this variability a...

journal_title：JAMA ophthalmology

authors： Lorés-Motta L,Riaz M,Grunin M,Corominas J,van Asten F,Pauper M,Leenders M,Richardson AJ,Muether P,Cree AJ,Griffiths HL,Pham C,Belanger MC,Meester-Smoor MA,Ali M,Heid IM,Fritsche LG,Chakravarthy U,Gale R,McKibbin M,

更新日期：2018-08-01 00:00:00

abstract：Importance:The number and size of guttae increase over time in Fuchs endothelial corneal dystrophy (FECD); however, the association between these physical parameters and disease pathogenesis is unclear. Objective:To determine the role of guttae in corneal endothelial cell function. Design, Settings, and Participants:...

journal_title：JAMA ophthalmology

authors： Kocaba V,Katikireddy KR,Gipson I,Price MO,Price FW,Jurkunas UV

更新日期：2018-08-01 00:00:00

abstract：Importance:Unverifiable publications in applications for ophthalmology residencies could be a serious concern if they represent publication dishonesty. Objective:To determine the rate of unverifiable publications among applicants offered an interview. Design:Retrospective review of 322 ophthalmology residency applica...

journal_title：JAMA ophthalmology

authors： Tamez HM,Tauscher R,Brown EN,Wayman L,Mawn LA

更新日期：2018-06-01 00:00:00

abstract：Importance:Although low-income populations have more eye problems, whether they face greater difficulty obtaining eye care appointments is unknown. Objective:To compare rates of obtaining eye care appointments and appointment wait times for those with Medicaid vs those with private insurance. Design, Setting, and Par...

journal_title：JAMA ophthalmology

authors： Lee YH,Chen AX,Varadaraj V,Hong GH,Chen Y,Friedman DS,Stein JD,Kourgialis N,Ehrlich JR

更新日期：2018-06-01 00:00:00

abstract：Importance:It is well established from different population-based studies that visual impairment is associated with increased mortality rate. However, to our knowledge, the association of visual impairment with increased mortality rate has not been reported among indigenous Australian individuals. Objective:To assess ...

journal_title：JAMA ophthalmology

authors： Ng SK,Kahawita S,Andrew NH,Henderson T,Craig JE,Landers J

更新日期：2018-05-01 00:00:00

abstract：Importance:This study used optical coherence tomographic angiography to assess for impaired blood flow in myopic eyes with or without open-angle glaucoma. Objective:To compare the peripapillary perfused capillary density (PCD) between eyes with and without glaucoma. Design, Setting, and Participants:In this cross-sec...

journal_title：JAMA ophthalmology

authors： Suwan Y,Fard MA,Geyman LS,Tantraworasin A,Chui TY,Rosen RB,Ritch R

更新日期：2018-05-01 00:00:00

abstract：Importance:Immune checkpoint inhibitors, including antiprogrammed cell death protein-1 (anti-PD-1) and antiprogrammed cell death ligand-1 (anti-PD-L1) monoclonal antibodies, have recently been introduced as a promising new immunotherapy for solid cancers. The adverse effects typically include inflammation of the skin, ...

journal_title：JAMA ophthalmology

authors： Thomas M,Armenti ST,Ayres MB,Demirci H

更新日期：2018-05-01 00:00:00

abstract：Importance:Examining costs and consequences of different low-vision (LV) programs provides important information about resources needed to expand treatment options efficiently. Objective:To examine the costs and consequences of LV rehabilitation or basic LV services. Design, Setting, and Participants:The US Departmen...

journal_title：JAMA ophthalmology

authors： Stroupe KT,Stelmack JA,Tang XC,Wei Y,Sayers S,Reda DJ,Kwon E,Massof RW,LOVIT II Study Group.

更新日期：2018-05-01 00:00:00