abstract：BACKGROUND:Although there is increased understanding of the alopecia areata (AA) pathogenesis based on studies in scalp tissues, little is known about its systemic profile. OBJECTIVE:To evaluate the blood proteomic signature of AA and determine biomarkers associated with increased disease severity. METHODS:In a cross...

journal_title：Journal of the American Academy of Dermatology

authors： Glickman JW,Dubin C,Renert-Yuval Y,Dahabreh D,Kimmel GW,Auyeung K,Estrada YD,Singer G,Krueger JG,Pavel AB,Guttman-Yassky E

更新日期：2021-02-01 00:00:00

abstract：:Allergic contact dermatitis (ACD), a delayed hypersensitivity skin reaction to environmental allergens, has a prevalence that is similar in children and adults. However, diagnostic testing for ACD in pediatric populations accounts for less than one tenth of all patch tests. The relative infrequency of pediatric patch ...

journal_title：Journal of the American Academy of Dermatology

authors： Neale H,Garza-Mayers AC,Tam I,Yu J

更新日期：2021-02-01 00:00:00

abstract：:Cutaneous surgery has become critical to comprehensive dermatologic care, and dermatologists must therefore be equipped to manage the risks associated with surgical procedures. As complications may occur at any point along the continuum of care, assessing, managing and preventing risk from beginning to end becomes ess...

journal_title：Journal of the American Academy of Dermatology

authors： Strickler AG,Shah P,Bajaj S,Mizuguchi R,Nijhawan RI,Odueyungbo M,Rossi A,Ratner D

更新日期：2021-01-23 00:00:00

abstract：:Twenty percent of Americans will be over age 65 by 2030,1 and without a dedicated geriatrics curriculum in many residency trainings programs, dermatologists may be less familiar with age-associated side effects of common dermatologic medications. Herein, we provide a practical guide and clinical safety pearls for the ...

journal_title：Journal of the American Academy of Dermatology

authors： Grinnell M,Price KN,Shah A,Butler D

更新日期：2021-01-16 00:00:00

abstract：:The Fourth Annual Symposium on Hidradenitis Suppurativa (SHSA) took place on November 1-3, 2019, at the Westin Book Cadillac Hotel in Detroit, Michigan. This symposium was a joint meeting of the US Hidradenitis Suppurativa Foundation and the Canadian Hidradenitis Suppurativa Foundation. This cross-disciplinary meeting...

journal_title：Journal of the American Academy of Dermatology

authors： Narla S,Price KN,Sachdeva M,Shah M,Shi V,Hamzavi I,Alavi A,Lowes MA

更新日期：2021-01-01 00:00:00

abstract：:Reflectance confocal microscopy (RCM) is a high-resolution, noninvasive tool that is currently approved by the US Food and Drug Administration for obtaining and interpreting images of the skin and cutaneous neoplasms with the goal of decreasing unnecessary biopsy procedures in patients with benign lesions. The second ...

journal_title：Journal of the American Academy of Dermatology

authors： Shahriari N,Grant-Kels JM,Rabinovitz H,Oliviero M,Scope A

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The effects of systemic therapy on mortality risk among patients with psoriasis are not fully understood. OBJECTIVE:To evaluate the impact of systemic treatment on mortality risk in patients enrolled in the Psoriasis Longitudinal Assessment and Registry. METHODS:Nested case-control analyses were performed ...

journal_title：Journal of the American Academy of Dermatology

authors： Langley RG,Poulin Y,Srivastava B,Lafferty KP,Fakharzadeh S,Langholff W,Augustin M

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The co-existence of hidradenitis suppurativa (HS) and atopic dermatitis (AD) had been reported but was not investigated in controlled studies. OBJECTIVE:To evaluate the bidirectional association between HS and AD. METHODS:A population-based retrospective cohort study was conducted to compare incidence rate...

journal_title：Journal of the American Academy of Dermatology

authors： Sherman S,Kridin K,Bitan DT,Leshem YA,Hodak E,Cohen AD

更新日期：2020-12-27 00:00:00

abstract：INTRODUCTION:Low-dose total skin electron beam therapy provides a durable treatment response for skin lesions caused by cutaneous T-cell lymphoma. We prospectively assessed the durability of response and quality of life for patients receiving low-dose total skin electron beam therapy using a novel rotational technique ...

journal_title：Journal of the American Academy of Dermatology

authors： Newman NB,Patel CG,Ding GX,Zic JA,Zwerner J,Osmundson EC,Kirschner AN

更新日期：2020-12-14 00:00:00

abstract：BACKGROUND:Patients with epidermal nevi strongly demand cosmetic improvement. Laser treatment appears appealing and is frequently used in clinical practice. Nevertheless, large series with long-term follow-up are missing, preventing definitive conclusions about its real benefit. OBJECTIVE:To evaluate the long-term eff...

journal_title：Journal of the American Academy of Dermatology

authors： Alkhalifah A,Fransen F,Le Duff F,Lacour JP,Wolkerstorfer A,Passeron T

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Evidence on long-term dupilumab treatment for atopic dermatitis in daily practice is lacking. OBJECTIVE:To investigate patient characteristics, treatment aspects, effectiveness, and safety of up to 84 weeks of dupilumab treatment. METHODS:An observational prospective cohort study was conducted of patients ...

journal_title：Journal of the American Academy of Dermatology

authors： Bosma AL,de Wijs LEM,Hof MH,van Nieuwenhuizen BR,Gerbens LAA,Middelkamp-Hup MA,Hijnen D,Spuls PI

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:T-cell receptor (TCR) clonality may help establish a diagnosis of mycosis fungoides (MF). Routine clonality analysis is performed by using a polymerase chain reaction TCR- gamma assay, yet with this method, 10% to 50% of T-cell lymphomas escape detection. TCR- beta gene rearrangement is an additional assay. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schachter O,Tabibian-Keissar H,Debby A,Segal O,Baum S,Barzilai A

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Surgeons use absorbable and nonabsorbable sutures for epidermal wound closure. No large, randomized studies have compared the effect of these suture types on facial scar appearance. OBJECTIVE:To assess postsurgical facial scar appearance using either rapidly absorbable polyglactin 910 or nylon for epidermal...

journal_title：Journal of the American Academy of Dermatology

authors： Moran B,Humphrey S,Seal A,Berkowitz J,Zloty D

更新日期：2020-11-01 00:00:00

abstract：CAPSULE SUMMARY:In this article, we try to use the syringes without the piston part to control the amount of saline fluid in dermabrasion surgery. It is very convenient to obtain materials and simple to operate in skin surgery. ...

journal_title：Journal of the American Academy of Dermatology

authors： Cao C,Li H,Shao Z

更新日期：2020-10-10 00:00:00

abstract：BACKGROUND:Flushing and erythema are frequent skin symptoms in rosacea. Because their adequate treatment remains a clinical challenge, new treatment options are explored, such as oral β-blockers. OBJECTIVES:To evaluate the efficacy of oral β-blockers for rosacea-associated facial flushing and erythema. METHODS:PubMed...

journal_title：Journal of the American Academy of Dermatology

authors： Logger JGM,Olydam JI,Driessen RJB

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Spironolactone is used off-label for androgenic alopecia because of its ability to arrest hair loss progression and long-term safety profile. However, little is known about the safety of spironolactone in breast cancer (BC) survivors. Because spironolactone has estrogenic effects, there is a theoretical risk...

journal_title：Journal of the American Academy of Dermatology

authors： Wei C,Bovonratwet P,Gu A,Moawad G,Silverberg JI,Friedman AJ

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:It is important for dermatologists and other physicians in refugee-receiving countries to acquire knowledge of forensic dermatology to identify lesions from torture. OBJECTIVE:Review forensic dermatology in cases of torture. RESULTS:In providing medical assessment and care to refugees and migrants, chronic...

journal_title：Journal of the American Academy of Dermatology

authors： Deps PD,Aborghetti HP,Zambon TL,Costa VC,Dadalto Dos Santos J,Collin SM,Charlier P

更新日期：2020-09-15 00:00:00

abstract：:The Publisher regrets that this article is an accidental duplication of an article that has already been published, https://doi.org/10.1016/j.jaad.2020.09.006. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/...

journal_title：Journal of the American Academy of Dermatology

authors： Elston DM

更新日期：2020-09-14 00:00:00

abstract：:The Publisher regrets that this article is an accidental duplication of an article that has already been published, https://doi.org/10.1016/j.jaad.2020.09.005. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/...

journal_title：Journal of the American Academy of Dermatology

authors： Elston DM

更新日期：2020-09-11 00:00:00

abstract：BACKGROUND:No large studies have defined the best treatment of actinic cheilitis. METHODS:We conducted a systematic review to define the best therapies for actinic cheilitis in clinical response and recurrences. RESULTS:We first identified 444 papers, and 49 were finally considered, including 789 patients and 843 tre...

journal_title：Journal of the American Academy of Dermatology

authors： Lai M,Pampena R,Cornacchia L,Pellacani G,Peris K,Longo C

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Although most patients with cutaneous melanoma are non-Hispanic whites (NHWs), minorities consistently suffer worse melanoma-specific survival (MSS). Much of the literature comes from analyses of registries from the 1990s and 2000s. OBJECTIVE:We sought to evaluate whether and to what degree racial disparity...

journal_title：Journal of the American Academy of Dermatology

authors： Qian Y,Johannet P,Sawyers A,Yu J,Osman I,Zhong J

更新日期：2020-08-27 00:00:00

abstract：:Palliative care has been shown to improve quality of life, symptom, and caregiver burden for a range of life-limiting diseases. Palliative care use among patients with severe dermatologic disease remain relatively unexplored, but the limited available data suggest significant unmet care needs and low rates of palliati...

journal_title：Journal of the American Academy of Dermatology

authors： Thompson LL,Chen ST,Lawton A,Charrow A

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Novel picosecond lasers have been available for various pigmentary disorders. However, there are limited data directly comparing picosecond lasers and Q-switched lasers for treatment of nevus of Ota. OBJECTIVE:To compare the efficacy and safety of a picosecond alexandrite laser (PSAL) with a Q-switched alex...

journal_title：Journal of the American Academy of Dermatology

authors： Ge Y,Yang Y,Guo L,Zhang M,Wu Q,Zeng R,Rong H,Jia G,Shi H,Fang J,Lin T

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Basal cell carcinomas (BCCs) with high-risk features are preferably treated by Mohs micrographic surgery. Studies have shown clinicopathologic characteristics that may predict more stages required for clearance. However, few studies have correlated such factors with the number of millimeters removed per stag...

journal_title：Journal of the American Academy of Dermatology

authors： Cerci FB,Kubo EM,Werner B,Tolkachjov SN

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:There is lack of studies on the diagnostic accuracy of dermatoscopy and reflectance confocal microscopy (RCM) for dark pigmented lesions. OBJECTIVE:To assess the diagnostic accuracy of dermatoscopy plus confocal microscopy for melanoma diagnosis of dark pigmented lesions in real life. METHODS:Prospective a...

journal_title：Journal of the American Academy of Dermatology

authors： Longo C,Mazzeo M,Raucci M,Cornacchia L,Lai M,Bianchi L,Peris K,Pampena R,Pellacani G

更新日期：2020-07-27 00:00:00

abstract：BACKGROUND:There is limited data on zoster recurrence. OBJECTIVE:To examine in detail zoster recurrence in a population-based cohort. METHODS:Using data from a large cohort (The 45 and Up Study) with linked medical data (2004-2015), the incidence of first and recurrent zoster was examined using survival analyses meth...

journal_title：Journal of the American Academy of Dermatology

authors： Qian J,Macartney K,Heywood AE,Sheridan S,Liu B

更新日期：2020-07-02 00:00:00

abstract：:Talimogene laherparepvec (T-VEC) is an oncolytic virus based on herpes simplex virus type 1 approved for intralesional treatment of advanced melanoma. In this article, we review the clinical literature on T-VEC for advanced melanoma and provide a practical approach to using T-VEC in the dermatologic surgery and oncolo...

journal_title：Journal of the American Academy of Dermatology

authors： Haitz K,Khosravi H,Lin JY,Menge T,Nambudiri VE

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:For persons of childbearing potential prescribed isotretinoin, the iPLEDGE program requires use of 2 simultaneous methods of contraception or commitment to abstinence. OBJECTIVE:To model the relative effectiveness of a variety of contraception strategies for patients taking isotretinoin, including those tha...

journal_title：Journal of the American Academy of Dermatology

authors： Barbieri JS,Roe AH,Mostaghimi A

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Few effective treatments are available for male pattern hair loss (MPHL) or, especially, for female pattern hair loss (FPHL). Recently, cell-based therapies using autologous or allogeneic cells have been used clinically. OBJECTIVE:We examined the safety and efficacy of autologous cell-based therapy using de...

journal_title：Journal of the American Academy of Dermatology

authors： Tsuboi R,Niiyama S,Irisawa R,Harada K,Nakazawa Y,Kishimoto J

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Chemotherapy-induced alopecia is psychologically challenging for patients undergoing cancer treatment, and scalp cooling has been shown to prevent or decrease the hair loss. METHODS:Cancer treatment centers offering scalp cooling were identified using data from The Rapunzel Project. Medicare claims data w...

journal_title：Journal of the American Academy of Dermatology

authors： Singer S,Tkachenko E,Sharma P,Nelson C,Mostaghimi A,LeBoeuf NR

更新日期：2020-06-28 00:00:00

abstract：BACKGROUND:The use of immunotherapies in the treatment of metastatic cancers has significantly advanced oncology. However, due to safety concerns, solid organ transplant recipients (SOTRs) are routinely excluded from immunotherapy trials; thus, there is limited data for these agents in this population. METHODS:A syste...

journal_title：Journal of the American Academy of Dermatology

authors： Fisher J,Zeitouni N,Fan W,Samie FH

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD) is associated with mental health disorders, but its impact on global mental health symptoms is less clear. OBJECTIVE:To determine the association between pediatric AD and mental health impairment. METHODS:In a cross-sectional study using 2013-2017 United States National Health Interv...

journal_title：Journal of the American Academy of Dermatology

authors： Wan J,Takeshita J,Shin DB,Gelfand JM

更新日期：2020-06-01 00:00:00

abstract：:The most problematic vulvovaginal conditions are familiar to dermatologists but may exhibit distinct clinical features or medication management because of the anatomic location. The second article in this continuing medical education series focuses on management pearls for treating vulvar diseases. We highlight key co...

journal_title：Journal of the American Academy of Dermatology

authors： Mauskar MM,Marathe K,Venkatesan A,Schlosser BJ,Edwards L

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD), a chronic, highly pruritic skin disorder, impairs quality of life (QoL). Janus kinase inhibitors suppress inflammatory and pruritus-associated cytokine signaling in AD. OBJECTIVE:To report the effects of ruxolitinib (RUX) cream on itch and QoL in AD. METHODS:A total of 307 adult pat...

journal_title：Journal of the American Academy of Dermatology

authors： Kim BS,Sun K,Papp K,Venturanza M,Nasir A,Kuligowski ME

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Topical corticosteroids alone or in combination with other therapies are widely used to treat mycosis fungoides (MF), but data on response rates to their use as monotherapy in MF are limited. OBJECTIVE:To evaluate the efficacy of topical corticosteroid monotherapy in MF; compare sex, age, stage distribution...

journal_title：Journal of the American Academy of Dermatology

authors： Kartan S,Shalabi D,O'Donnell M,Alpdogan SO,Sahu J,Shi W,Porcu P,Cha J,Nikbakht N

更新日期：2020-05-16 00:00:00

abstract：BACKGROUND:Biologic agents may predispose patients to skin and soft tissue infections (SSTIs). Guidelines recommend discontinuing the agent pre-operatively; the true risk of infection is unclear. OBJECTIVES:To assess the incidence of SSTIs in patients on biologic agents for all clinical indications. A secondary aim is...

journal_title：Journal of the American Academy of Dermatology

authors： Nguyen ED,Gabel CK,Kroshinsky D

更新日期：2020-05-05 00:00:00

abstract：:The treatment of hidradenitis suppurativa (HS) has remained challenging because of the many knowledge gaps regarding etiology. However, recent studies into the pathogenesis of HS have enabled the investigation of newer therapies. The second article in this continuing medical education series reviews the evidence for e...

journal_title：Journal of the American Academy of Dermatology

authors： Goldburg SR,Strober BE,Payette MJ

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:The Patient-Reported Outcomes Measurement Information System (PROMIS) Itch Questionnaire (PIQ) was recently developed. OBJECTIVE:To validate PIQ short forms in adults with AD. METHODS:Self-administered questionnaires and skin examinations were performed in 239 adults with atopic dermatitis (AD) in a dermat...

journal_title：Journal of the American Academy of Dermatology

authors： Silverberg JI,Lai JS,Vakharia PP,Patel K,Singam V,Chopra R,Sacotte R,Patel N,Rastogi S,Kantor R,Hsu DY,Cella D

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Appropriate primary end points in randomized controlled trials (RCTs) improve the quality of the measurement and enable comparison of the findings with those of other trials. OBJECTIVE:To assess the quality of reporting primary end points in RCTs recently published in dermatology journals. METHODS:We ident...

journal_title：Journal of the American Academy of Dermatology

authors： Kim DY,Oh S,Yoon HS

更新日期：2020-04-22 00:00:00

abstract：BACKGROUND:Several studies have found that the microbiota of psoriatic lesions is different from that of healthy skin. OBJECTIVE:To characterize the microbiota of lesional and unaffected skin in patients with psoriasis and controls and investigate the correlation between cutaneous microbiota and clinical features of p...

journal_title：Journal of the American Academy of Dermatology

authors： Quan C,Chen XY,Li X,Xue F,Chen LH,Liu N,Wang B,Wang LQ,Wang XP,Yang H,Zheng J

更新日期：2020-04-01 00:00:00