解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Faecal microbiota transfer (FMT) consists of the infusion of donor faecal material into the intestine of a patient with the aim to restore a disturbed gut microbiota. In this study, it was investigated whether FMT has an effect on faecal microbial composition, its functional capacity, faecal metabolite profiles and th...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2020.0010
更新日期:2020-12-22 00:00:00
abstract::The establishment of the gut microbiota immediately after birth is a dynamic process that may impact lifelong health. At this important developmental stage in early life, human milk oligosaccharides (HMOs) serve as specific substrates to shape the gut microbiota of the nursling. The well-orchestrated transition is imp...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2020.0005
更新日期:2020-11-16 00:00:00
abstract::Nutritional intervention studies, like those with pre- and probiotics, are often hampered by low effect sizes, reducing the power to demonstrate potential efficacy. Here, we perform computer simulations of a hypothetical clinical trial using such an intervention in order to elucidate determining factors that can be in...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2020.0044
更新日期:2020-10-12 00:00:00
abstract::Vaccination is one of the most important prevention tools providing protection against infectious diseases especially in children below the age of five. According to estimates, more than 5 million lives are saved annually by the implementation of six standard vaccines, including diphtheria, hepatitis B, Haemophilus in...
journal_title:Beneficial microbes
pub_type: 杂志文章,评审
doi:10.3920/BM2019.0121
更新日期:2020-05-11 00:00:00
abstract::Intestinal and human milk microbiota studies during infancy have shown variations according to geographical location, delivery mode, gestational age, and mother-related factors during pregnancy. In this study, we performed metagenomic mycobiota analyses of 44 transient and mature human milk among five different groups...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2019.0158
更新日期:2020-03-27 00:00:00
abstract::This study evaluated the effects of Bifidobacterium longum 51A on the intestinal mucosa and inflammatory response in experimental colitis. Colitis was induced by administration of 3.5% dextran sodium sulphate (DSS) solution for 7 days. Two periods of administration were performed: treatment (T) group, mice received Bi...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2019.0098
更新日期:2020-02-19 00:00:00
abstract::Few studies have examined the effects of smoking habit, the frequency of alcohol drinking, exercise, and fermented milk consumption on defecatory symptoms and gut microbiota composition, and particularly their interactive effects. We examined the effect of these lifestyle factors on bowel movements and gut microbiota ...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2019.0057
更新日期:2019-12-09 00:00:00
abstract::The past definitions of probiotics and prebiotics have been reviewed and updated recently. According to these concepts, probiotics comprise live microorganisms that confer a health benefit on the host when administered in adequate amounts, whereas a prebiotic is a substrate that is selectively utilised by host microor...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2019.0015
更新日期:2019-10-14 00:00:00
abstract::Hypercholesterolemia is a main risk factor of cardiovascular disease. Probiotics are a safe approach to reduce elevated cholesterol without any deleterious effect to human health. Saccharomyces boulardii CNCM I-745 probiotic properties are well documented in a context of intestinal dysbiosis. Recent in vitro and precl...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2018.0134
更新日期:2019-05-28 00:00:00
abstract::The human body is exposed to many xenobiotic, potentially harmful compounds. The intestinal immune system is crucial in protecting the human body from these substances. Moreover, many microorganisms, residing in the gastrointestinal tract, play an important role in modulating immune responses. Pre- and probiotics may ...
journal_title:Beneficial microbes
pub_type: 杂志文章,评审
doi:10.3920/BM2018.0066
更新日期:2019-04-19 00:00:00
abstract::Bacteriocins are bacterially-produced antimicrobial peptides that have killing activity principally against other relatively closely-related bacteria. Some bacteriocins of the lactic acid bacteria (LAB) have for many years been extensively applied in food biopreservation. However, especially during the last decade, a ...
journal_title:Beneficial microbes
pub_type: 杂志文章,评审
doi:10.3920/BM2018.0126
更新日期:2019-04-19 00:00:00
abstract::The gut is hypothesised to play an important role in the development and progression of sepsis. It is however unknown whether the gut microbiome and the gut barrier function is already altered early in sepsis development and whether it is possible to modulate the microbiome in early sepsis. Therefore, a randomised, do...
journal_title:Beneficial microbes
pub_type: 杂志文章,随机对照试验
doi:10.3920/BM2018.0067
更新日期:2019-04-19 00:00:00
abstract::Little is known about the prevalence of persistent human infections by nontyphoidal Salmonella (NTS). Recently published study results indicate that a small fraction (at least 2.2%) of NTS-infected patients continue to shed Salmonella for an extended period of time (up to years). Despite the recommendation not to use ...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2018.0080
更新日期:2019-03-13 00:00:00
abstract::The gut microbiota contributes to host energy metabolism, and altered gut microbiota has been associated with obesity-related metabolic disorders. We previously reported that a probiotic alone or together with a prebiotic controls body fat mass in healthy overweight or obese individuals in a randomised, double-blind, ...
journal_title:Beneficial microbes
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3920/BM2018.0028
更新日期:2019-03-13 00:00:00
abstract::Lactobacillus paracasei K5 is a lactic acid bacteria (LAB) strain, isolated recently from feta-type cheese. Its probiotic potential has been demonstrated in a series of established in vitro tests. Moreover, incorporation of L. paracasei K5 as starter culture offered organoleptic and technological advantages to novel f...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2017.0183
更新日期:2018-12-07 00:00:00
abstract::The mechanism of neurodegeneration in Parkinson's disease (PD) remains unknown but it has been hypothesised that the intestinal tract could be an initiating and contributing factor to the neurodegenerative processes. In PD patients as well as in animal models for PD, alpha-synuclein-positive enteric neurons in the col...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2017.0202
更新日期:2018-09-18 00:00:00
abstract::Ulcerative colitis is a type of chronic inflammation present in the intestines for which the aetiology is not yet clear. The current therapies for ulcerative colitis cannot be considered to be long-term management strategies due to their significant side effects. Therefore, it is essential to identify an alternative t...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2017.0035
更新日期:2018-09-18 00:00:00
abstract::The gut microbiota plays a crucial role in gastrointestinal health. Current use of probiotics is aimed at modulating the bacterial gut composition to alleviate specific diseases. The safety and tolerance of three probiotic strains (Bifidobacterium longum subsp. infantis R0033, Lactobacillus helveticus R0052 and Bifido...
journal_title:Beneficial microbes
pub_type: 杂志文章,随机对照试验
doi:10.3920/BM2017.0132
更新日期:2018-06-15 00:00:00
abstract::Evidence suggests that the gut microbiota might play an important role in fibromyalgia syndrome (FMS) and chronic fatigue syndrome (CFS). Our goal is to systematically review the reported effect of probiotic treatments in patients diagnosed with FMS or CFS. A systematic review was carried out using 14 databases (PubMe...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2017.0125
更新日期:2018-06-15 00:00:00
abstract::The use of native microorganisms with probiotic capacity is an alternative tool for the treatment and prevention of several diseases that affect animals, such as neonatal calf diarrhoea. The selection of probiotic strains within a collection is based on different in vitro and in vivo assays, which predict their potent...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2017.0131
更新日期:2018-06-15 00:00:00
abstract::Obesity is highly correlated with the dysbiosis of intestinal microbiota, and bifidobacteria are one of the soft targets of this metabolic syndrome. The aim of this study is to evaluate the efficacy of Bifidobacterium sp. MKK4 and rice-based fermented foods on physical, haematological, gut microbiota and lypogenic-lyp...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2017.0056
更新日期:2018-04-25 00:00:00
abstract::Bacterial vaginosis (BV) is characterised by a depletion of lactobacilli in favour of an overgrowth of anaerobic bacteria. It is associated with increased risk for urogenital infections and abortion. In this study we assessed the effect of a yoghurt drink containing Lactobacillus strains on BV. The strains had been is...
journal_title:Beneficial microbes
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3920/BM2017.0018
更新日期:2018-01-29 00:00:00
abstract::Dysbiosis may contribute to constipation and its symptoms, therefore probiotic administration could improve significantly gut health and functions. The aim of the study was to investigate the effects of a long-lasting administration of Lactobacillus reuteri DSM 17938 (LR DSM 17938) on symptoms and quality of life (QoL...
journal_title:Beneficial microbes
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3920/BM2017.0049
更新日期:2018-01-29 00:00:00
abstract::Gut microbiota affects the host's metabolism, and it is suggested that there are differences in gut microbiota composition between patients with type 2 diabetes and healthy individuals. Additionally, dysbiosis may increase the concentration of lipopolysaccharides (LPS), causing metabolic endotoxemia, which induces imp...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2016.0230
更新日期:2017-10-13 00:00:00
abstract::Knee osteoarthritis (OA) treatment is challenging due to inefficacy and adverse effects of current medications. Probiotic treatment has been shown to promote bone metabolism, reduce pain and inflammatory responses of age-related musculoskeletal disorders, including OA. We aimed to investigate the effect of probiotic L...
journal_title:Beneficial microbes
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3920/BM2016.0207
更新日期:2017-10-13 00:00:00
abstract::Ingestion of milks fermented by Lactobacillus strains showing probiotic properties is an important tool to maintain gastrointestinal health. In this study, Lactobacillus rhamnosus D1 and Lactobacillus plantarum B7, isolated from Brazilian artisanal cheese, were used as starters for the functional fermented milks to as...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2016.0163
更新日期:2017-08-24 00:00:00
abstract::There are few data regarding the role of probiotics as a dietary intervention in the management of obesity in children. An open prospective examination was conducted to clarify the effects of Lactobacillus casei strain Shirota (LcS)-containing beverages in obese children. We compared the intestinal microbiota and orga...
journal_title:Beneficial microbes
pub_type: 临床试验,杂志文章
doi:10.3920/BM2016.0170
更新日期:2017-08-24 00:00:00
abstract::Many studies have highlighted the immunomodulatory properties of the probiotic strain Lactobacillus casei BL23. Recently, we demonstrated the ability of this strain to modulate the Th2-oriented immune response in a mouse model of cow's milk allergy based on the induction of a Th17-biased immune response. The probiotic...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2016.0174
更新日期:2017-05-30 00:00:00
abstract::The anaerobic gut bacterium Akkermansia muciniphila is a well-characterised member of the mucosal microbiota and has shown to be a gut symbiont in human. A. muciniphila has been negatively associated with obesity and its associated metabolic disorders in various human cohorts while treatment with A. muciniphila cells ...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2016.0096
更新日期:2017-04-26 00:00:00
abstract::There is growing interest in the use of probiotic lactic acid bacteria (LAB) for prevention of hypercholesterolaemia. This study assessed the cholesterol lowering ability of Pediococcus acidilactici LAB4 and Lactobacillus plantarum LAB12 in growth media. Both LAB yielded >98% (39.2 μg/ml) cholesterol lowering in growt...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2016.0048
更新日期:2017-02-07 00:00:00
abstract::The oral administration of Enterococcus faecium EF1 to new-born suckling and weaning piglets along with their growth performances and intestinal microbiota was investigated in this study. Twenty-four new-born piglets were initially divided into 2 groups. The probiotics group received 2 ml of 10% sterilised skimmed mil...
journal_title:Beneficial microbes
pub_type: 杂志文章,随机对照试验
doi:10.3920/BM2015.0099
更新日期:2016-09-01 00:00:00
abstract::We previously reported that dietary heat-killed Lactobacillus brevis SBC8803 affects sleep rhythms in mice. The present study evaluated the effect of consumption of heat-killed SBC8803 on sleep architecture in humans. A non-randomised, placebo-controlled, double blind, and crossover pilot study was conducted using vol...
journal_title:Beneficial microbes
pub_type: 临床试验,杂志文章
doi:10.3920/BM2015.0118
更新日期:2016-09-01 00:00:00
abstract::The probiotic strain Bifidobacterium bifidum YIT 10347 has been demonstrated to inhibit Helicobacter pylori activity, prevent injury to the gastric mucosa, and improve general gastric malaise symptoms in H. pylori positive patients. This study aimed to investigate the adhering activity and localisation of B. bifidum Y...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2015.0138
更新日期:2016-06-01 00:00:00
abstract::Gut microbiota and gut-associated lymphoid tissue have been increasingly appreciated as important players in pathogenesis of various autoimmune diseases, including multiple sclerosis. Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis that can be induced with an injection of spina...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2015.0159
更新日期:2016-06-01 00:00:00
abstract::Necrotising enterocolitis (NEC) is associated with inflammatory responses and barrier dysfunction in the gut. In this study, we investigated the effect of Bifidobacterium breve M-16V on factors related to NEC development using an experimental rat model. Caesarean-sectioned rats were given formula milk with or without ...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2015.0035
更新日期:2016-02-01 00:00:00
abstract::Listeria monocytogenes is an opportunistic food-borne pathogen and is life-threatening to individuals with a weakened immune system. The aim of this study was to determine if Lactobacillus plantarum 423 and Enterococcus mundtii ST4SA could prevent colonisation of L. monocytogenes in the gastro-intestinal tract (GIT). ...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2015.0082
更新日期:2016-01-01 00:00:00
abstract::In concern to the continuously rising global prevalence of obesity, diabetes and associated diseases, novel preventive and therapeutic approaches are urgently required. However, to explore and develop such innovative strategies, a meticulous comprehension of the biological basis of these diseases is extremely importan...
journal_title:Beneficial microbes
pub_type: 杂志文章,评审
doi:10.3920/bm2015.0062
更新日期:2016-01-01 00:00:00
abstract::This study aimed to systematically evaluate safety of probiotics and synbiotics in immune compromised adults (≥18 years). Safety was analysed using the Common Terminology Clinical Adverse Events (CTCAE version 4.0) classification, thereby providing an update on previous reports using the most recent available clinical...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2014.0079
更新日期:2015-03-01 00:00:00
abstract::In the present study, the protective potential of Saccharomyces cerevisiae strain UFMG A-905 was evaluated in a murine model of acute ulcerative colitis (UC). Six groups of Balb/c mice were used: not treated with yeast and not challenged with dextran sulphate sodium (DSS) (control); treated with S. cerevisiae UFMG A-9...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2015.0018
更新日期:2015-01-01 00:00:00
abstract::Lactobacilli exhibit several health benefits in mammals, including humans. Our previous reports established that heat-killed Lactobacillus brevis SBC8803 (SBC8803) increased both efferent gastric vagal nerve activity and afferent intestinal vagal nerve activity in rats. We speculated that this strain could be useful f...
journal_title:Beneficial microbes
pub_type: 杂志文章
doi:10.3920/BM2015.0031
更新日期:2015-01-01 00:00:00