abstract：PURPOSE OF REVIEW:The pathogenesis and progression of coronary artery disease (CAD) is now known to be largely driven by inflammation on top of the well-accepted role for the disequilibrium between cholesterol deposition and removal from the arterial wall. Recent clinical trials have supported the inflammatory hypothes...

journal_title：Current cardiology reports

authors： Boland J,Long C

更新日期：2021-01-06 00:00:00

abstract：PURPOSE OF REVIEW:The present article reviews the pathophysiology of cardiac sympathetic denervation, the principles of positron emission tomography (PET) imaging of the sympathetic innervation of the heart and its potential clinical role, based on current and expected future evidence. RECENT FINDINGS:Imaging of cardi...

journal_title：Current cardiology reports

authors： van der Bijl P,Knuuti J,Delgado V,Bax JJ

更新日期：2020-11-27 00:00:00

abstract：PURPOSE OF REVIEW:The aim of low-density lipoprotein-cholesterol (LDL-C) lowering therapies is to safely achieve a consistent and long-term reduction in exposure of the vasculature to atherogenic lipoproteins in order to reduce the risk of atherosclerotic cardiovascular (CV) disease and the associated CV events, such a...

journal_title：Current cardiology reports

authors： Sinning D,Landmesser U

更新日期：2020-10-21 00:00:00

abstract：PURPOSE OF REVIEW:Although rare, sudden cardiac death (SCD) in the young is a tragic event, having a dramatic impact upon all involved. The psychosocial burden associated with SCD can leave friends, families, and entire communities bereft. With only limited evidence to describe the volatile emotional reactions associat...

journal_title：Current cardiology reports

authors： Grubic N,Puskas J,Phelan D,Fournier A,Martin LJ,Johri AM

更新日期：2020-10-10 00:00:00

abstract：PURPOSE OF REVIEW:Ebstein's anomaly (EA) is a rare, but complex form of congenital heart disease consisting of a right ventricular myopathy and morphologic tricuspid valve disease leading to a high incidence of right ventricular dysfunction and arrhythmias. This review offers an updated overview of the current understa...

journal_title：Current cardiology reports

authors： Possner M,Gensini FJ,Mauchley DC,Krieger EV,Steinberg ZL

更新日期：2020-10-09 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the effects of psychological stress on the physiology of the entire vascular system, from individual cellular components to macrovascular and microvascular responses, and highlights the importance of the vascular system in the context of current limitations in cardiac imaging for...

journal_title：Current cardiology reports

authors： Shah SM,Meadows JL,Burg MM,Pfau S,Soufer R

更新日期：2020-10-09 00:00:00

abstract：:On page 2 of the original publication, in the section on TTR Silencers dosing of patisiran in the APOLLO study was stated as being given every 3 months; this is inaccurate as patisiran was dosed every 3 weeks in the APOLLO study. ...

journal_title：Current cardiology reports

authors： Hough A,Wearden J,de Almeida K,Kaiser S

更新日期：2020-09-28 00:00:00

abstract：PURPOSE OF REVIEW:Cardiovascular magnetic resonance (CMR) provides the most comprehensive imaging assessment of pericardial disease, providing a three-dimensional assessment of the pericardium, functional assessment of its impact on cardiac contractility, and pericardial tissue/fluid characterization. This review prese...

journal_title：Current cardiology reports

authors： Abou Hassan OK,Kwon D

更新日期：2020-09-15 00:00:00

abstract：PURPOSE OF THE REVIEW:Atrial fibrillation (AF) is the most frequent arrhythmia in the general population. This review aims to provide a comprehensive overview of the psychological aspects of AF, compiling evidence from epidemiological, clinical, and basic research sources. RECENT FINDINGS:Findings from large-scale pop...

journal_title：Current cardiology reports

authors： Ladwig KH,Goette A,Atasoy S,Johar H

更新日期：2020-09-10 00:00:00

abstract：PURPOSE OF REVIEW:To determine if subsidizing the cost of a food-based intervention for managing hyperlipidemia could be cost-effective under commercial insurance and/or Medicare coverage scenarios. RECENT FINDINGS:A large number of patients eligible for pharmaceutical treatment of hyperlipidemia either cannot or will...

journal_title：Current cardiology reports

authors： Dong I,Klodas E

更新日期：2020-09-10 00:00:00

abstract：:The article title in the original publication contains a mistake. ...

journal_title：Current cardiology reports

authors： Edelson JB,Genuardi MV,Santangeli P,Birati EY

更新日期：2020-09-08 00:00:00

abstract：PURPOSE OF REVIEW:The development of biventricular repair and conversion pathways for patients with borderline hypoplastic heart disease represents an area of recent inquiry and innovation. This review summarizes emerging techniques and novel treatment algorithms for borderline hypoplastic heart disease with a focus on...

journal_title：Current cardiology reports

authors： Andersen ND,Scherba JC,Turek JW

更新日期：2020-08-08 00:00:00

abstract：PURPOSE OF REVIEW:Results from cardiovascular (CV) outcome trials have revealed important insights into the CV safety and efficacy of glucose-lowering agents, including dipeptidyl peptidase-4 inhibitors (DPP-4i) and glucagon-like peptide-1 receptor agonists (GLP-1RA). RECENT FINDINGS:Among patients with T2DM, DPP-4i h...

journal_title：Current cardiology reports

authors： Patel KV,Sarraju A,Neeland IJ,McGuire DK

更新日期：2020-08-08 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this report is to describe the main aspects of sex-related differences in non-ischemic dilated cardiomyopathies (DCM), focusing on chemotherapy-induced heart failure (HF) and investigating the possible therapeutic implications and clinical management applications in the era of personalized ...

journal_title：Current cardiology reports

authors： D'Amario D,Camilli M,Migliaro S,Canonico F,Galli M,Arcudi A,Montone RA,Borovac JA,Crea F,Savarese G

更新日期：2020-08-08 00:00:00

abstract：PURPOSE OF THE REVIEW:Moderate or severe aortic regurgitation (AR) occurs in 0.5% of the population and typically peaks in the fourth to sixth decade of life. A significant proportion of patients have prohibitive surgical risk and are therefore treated medically with pharmacological management of heart failure and no d...

journal_title：Current cardiology reports

authors： Markham R,Ghodsian M,Sharma R

更新日期：2020-07-28 00:00:00

abstract：PURPOSE OF REVIEW:Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are commonly used anti-hypertensive medications in a number of clinical settings. They are often used interchangeably, but we pose the provocative question as to whether they should be. We review the literature to evaluate for ...

journal_title：Current cardiology reports

authors： Turner JM,Kodali R

更新日期：2020-07-09 00:00:00

abstract：PURPOSE OF REVIEW:Heart failure with preserved ejection fraction (HFpEF) is a relatively new disease entity used in medical terminology; however, both the number of patients and its clinical significance are growing. HFpEF used to be seen as a mild condition; however, the symptoms and quality of life of the patients ar...

journal_title：Current cardiology reports

authors： Adamczak DM,Oduah MT,Kiebalo T,Nartowicz S,Bęben M,Pochylski M,Ciepłucha A,Gwizdała A,Lesiak M,Straburzyńska-Migaj E

更新日期：2020-07-09 00:00:00

abstract：PURPOSE OF REVIEW:Machine learning (ML) and deep learning (DL) are two important categories of AI algorithms. Nowadays, AI technology has been gradually applied to cardiac magnetic resonance imaging (CMRI), covering the fields of myocardial contrast enhancement (MCE) pattern and automatic ventricular segmentation. This...

journal_title：Current cardiology reports

authors： Tang F,Bai C,Zhao XX,Yuan WF

更新日期：2020-07-07 00:00:00

abstract：PURPOSE OF REVIEW:To examine the utility and methods of coronary artery disease (CAD) assessment in patients with new-onset heart failure with reduced ejection fraction (HFrEF) of unclear etiology. Moreover, we sought to review the role and techniques of assessing myocardial viability to guide coronary revascularizatio...

journal_title：Current cardiology reports

authors： Kassab K,Kattoor AJ,Doukky R

更新日期：2020-07-06 00:00:00

abstract：PURPOSE OF THE REVIEW:The aim of this review was to discuss the role of cardiac magnetic resonance (CMR) for the prognostic stratification of cardiomyopathies, highlighting strengths and limitations. RECENT FINDINGS:CMR is considered as a diagnostic pillar in the management of non-ischemic cardiomyopathies. Over the l...

journal_title：Current cardiology reports

authors： Grigoratos C,Todiere G,Barison A,Aquaro GD

更新日期：2020-06-19 00:00:00

abstract：PURPOSE OF REVIEW:Myocardial fibrosis (MF) arises due to myocardial infarction and numerous cardiac diseases. MF may lead to several heart disorders, such as heart failure, arrhythmias, and ischemia. Cardiac magnetic resonance (CMR) imaging techniques, such as late gadolinium enhancement (LGE) CMR, enable non-invasive ...

journal_title：Current cardiology reports

authors： Zabihollahy F,Rajan S,Ukwatta E

更新日期：2020-06-19 00:00:00

abstract：:The gold standard for diagnosis of cardiac amyloidosis (CA) is endomyocardial biopsy showing Congo red staining followed by mass spectroscopy, but the diagnosis can also be made with high certainty by demonstration of typical cardiac imaging features along with amyloid on biopsy of another involved organ. The use of c...

journal_title：Current cardiology reports

authors： Gallegos C,Miller EJ

更新日期：2020-05-19 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this paper is to review present knowledge regarding biological pacemakers created by somatic reprogramming as a platform for mechanistic and metabolic understanding of the rare subpopulation of pacemaker cells, with the ultimate goal of creating biological alternatives to electronic pacing...

journal_title：Current cardiology reports

authors： Xiao A,Cho HC

更新日期：2020-03-30 00:00:00

abstract：PURPOSE OF REVIEW:To review the clinical evidence on the use of percutaneous coronary intervention (PCI) revascularization options in left main (LM) disease in comparison with coronary artery bypass graft (CABG). Coronary artery disease (CAD) involving the LM is associated with high morbidity and mortality. Though CABG...

journal_title：Current cardiology reports

authors： Nagarajarao HS,Ojha CP,Mulukutla V,Ibrahim A,Mares AC,Paul TK

更新日期：2020-02-08 00:00:00

abstract：PURPOSE OF REVIEW:Innovation for transcatheter aortic valve replacement (TAVR) has transformed a medically complex treatment into a standardized procedure. While Edwards SAPIEN and Medtronic CoreValve occupy the market for TAVR in the United States (US), additional valve systems are being developed. The Boston Scientif...

journal_title：Current cardiology reports

authors： Seigerman ME,Nathan A,Anwaruddin S

更新日期：2019-11-25 00:00:00

abstract：PURPOSE OF REVIEW:To establish the actual role of CT in the growing field of transcatheter valve interventions (THV). RECENT FINDINGS:The development of empirical CT measurements, which are linked with outcomes. CT is a reliable technique for assessing risk and planning transcatheter valve interventions for mitral and...

journal_title：Current cardiology reports

authors： Godoy M,Mugharbil A,Anastasius M,Leipsic J

更新日期：2019-11-25 00:00:00

abstract：PURPOSE OF REVIEW:To describe lipid abnormalities in diabetes, when they occur and the evidence base for lipid management with established and new drugs to prevent diabetes complications. We also discuss how to manage statin intolerance. RECENT FINDINGS:Statins remain first-line therapy in patients with diabetes, thou...

journal_title：Current cardiology reports

authors： Sillars A,Sattar N

更新日期：2019-11-22 00:00:00

abstract：PURPOSE OF REVIEW:To analyze the current state of the art of functional mitral regurgitation (FMR) treatment. RECENT FINDINGS:The first-line treatment of severe FMR consists of guideline medical therapy (GMT) and resynchronization therapy when indicated; the impact of new medical therapies like sacubitril/valsartan ne...

journal_title：Current cardiology reports

authors： Fabris E,De Luca A,Vitrella G,Stolfo D,Masè M,Korcova R,Merlo M,Rakar S,Van't Hof AWJ,Kedhi E,Perkan A,Sinagra G

更新日期：2019-11-16 00:00:00

abstract：PURPOSE OF REVIEW:This review presents the current available evidence of the effects of several dietary patterns on atherosclerotic cardiovascular disease (ASCVD) risk in patients with type 2 diabetes (T2D). RECENT FINDINGS:Evidence demonstrates improvements in cardiovascular risk factors with some dietary patterns in...

journal_title：Current cardiology reports

authors： Liday C,Kirkpatrick C

更新日期：2019-10-17 00:00:00

abstract：PURPOSE OF REVIEW:The goal was to evaluate published data on the incidence, diagnosis, and management of symptomatic combined mitral and aortic valvular disease. Furthermore, to identify the role of treatment using contemporary transcatheter techniques. RECENT FINDINGS:Up to a quarter of symptomatic adult valvular dis...

journal_title：Current cardiology reports

authors： De Palma R,O'Sullivan CJ,Settergren M

更新日期：2019-09-13 00:00:00

abstract：PURPOSE OF REVIEW:Drug-coated balloons (DEB) and drug-eluting stents (DES) emerged as a tool to aid in lowering the rates of neointimal hyperplasia and target lesion restenosis following endovascular peripheral arterial disease (PAD) interventions. RECENT FINDINGS:Although the initial trials comparing these devices wi...

journal_title：Current cardiology reports

authors： Gad MM,Karrthik AK,Mahmoud AA,Mahmoud AN

更新日期：2019-09-07 00:00:00

abstract：PURPOSE OF REVIEW:Comprehensive discussion of alternative techniques in imaging coronary artery anomalies (CAAs) in different diagnostic scenarios. RECENT FINDINGS:At primary screening, intramural course essentially correlates with stenosis and clinical repercussion in some types of CAAs. Potential clinical aims in im...

journal_title：Current cardiology reports

authors： Angelini P

更新日期：2019-07-29 00:00:00

abstract：PURPOSE OF REVIEW:Magnetic resonance imaging (MRI) has enabled non-invasive myocardial tissue characterization in a wide range of cardiovascular diseases by quantifying several tissue specific parameters such as T1, T2, and T2* relaxation times. Simultaneous assessment of these parameters has recently gained interest t...

journal_title：Current cardiology reports

authors： Cruz G,Jaubert O,Botnar RM,Prieto C

更新日期：2019-07-27 00:00:00

abstract：PURPOSE OF REVIEW:Interventional cardiology and in particular the field of renal denervation is subject to constant change. This review provides an up to date overview of renal denervation trials and an outlook on what to expect in the future. RECENT FINDINGS:After the sham-controlled SYMPLICITY HTN-3 trial dampened t...

journal_title：Current cardiology reports

authors： Lauder L,Wolf MA,Scholz SS,Hohl M,Mahfoud F,Böhm M

更新日期：2019-07-05 00:00:00

abstract：PURPOSE OF REVIEW:The cardiovascular (CV) risk related to lipid disorders is well established and is based on a robust body of evidence from well-designed randomized clinical trials, as well as prospective observational studies. In the last two decades, significant advances have been made in understanding the genetic b...

journal_title：Current cardiology reports

authors： Stein R,Ferrari F,Scolari F

更新日期：2019-06-21 00:00:00

abstract：PURPOSE OF REVIEW:To summarize lifestyle interventions including pharmacological and non-pharmacological methods targeting modifiable risk factors and their impact on the future cardiovascular events in patients who have suffered transient ischemic attack (TIA) and/or ischemic stroke (IS). RECENT FINDINGS:The latest r...

journal_title：Current cardiology reports

authors： Vellipuram AR,Rodriguez G,Rawla P,Maud A,Cruz-Flores S,Khatri R

更新日期：2019-04-22 00:00:00

abstract：PURPOSE OF REVIEW:Coronary artery bypass grafting is a preferred strategy for complete coronary revascularization in patients who have multi-vessel coronary artery disease, left ventricular dysfunction, and/or diabetes. Both arterial (internal thoracic artery/radial artery) and venous grafts are utilized to bypass the ...

journal_title：Current cardiology reports

authors： Virk HUH,Lakhter V,Ahmed M,O' Murchu B,Chatterjee S

更新日期：2019-03-22 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the latest data on unprotected left main (ULM) percutaneous coronary intervention (PCI) versus coronary artery bypass graft (CABG) surgery, with a focus on the NOBLE and EXCEL trials. RECENT FINDINGS:In EXCEL trial, the primary endpoint at 3 years was 15.4% in the PCI group and 1...

journal_title：Current cardiology reports

authors： Taha Y,Patel RAG,Bagai J,Sachdeva R,Kumar G,Prasad A,Nathan S,Paul TK

更新日期：2019-03-18 00:00:00

abstract：PURPOSE OF REVIEW:The last 40 years of clinical research in interventional cardiology were extraordinarily innovative. This article will review the most promising up and coming interventional cardiovascular therapies, with a primary focus on the treatment of coronary artery disease. RECENT FINDINGS:From the first sten...

journal_title：Current cardiology reports

authors： Kerneis M,Nafee T,Yee MK,Kazmi HA,Datta S,Zeitouni M,Afzal MK,Jafarizade M,Walia SS,Qamar I,Pitliya A,Kalayci A,Al Khalfan F,Gibson CM

更新日期：2019-03-13 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the mechanisms of iron regulation in the brain and the pathophysiological role of deregulation of iron homeostasis following a stroke, and to review existing evidence supporting the potential role of iron chelators in the treatment of ischemic and hemorrhagic stroke. RECENT FINDINGS:In rec...

journal_title：Current cardiology reports

authors： Hanafy KA,Gomes JA,Selim M

更新日期：2019-03-04 00:00:00