Rationale and Current Evidence for Testing Iron Chelators for Treating Stroke.

abstract：PURPOSE OF REVIEW:Myocardial fibrosis (MF) arises due to myocardial infarction and numerous cardiac diseases. MF may lead to several heart disorders, such as heart failure, arrhythmias, and ischemia. Cardiac magnetic resonance (CMR) imaging techniques, such as late gadolinium enhancement (LGE) CMR, enable non-invasive ...

journal_title：Current cardiology reports

authors： Zabihollahy F,Rajan S,Ukwatta E

更新日期：2020-06-19 00:00:00

abstract：:Coronary artery bypass grafting without the aid of cardiopulmonary bypass (CPB) continues to gain popularity as an alternative to standard techniques of revascularization. CPB with cardioplegic arrest is associated with complications that may negate an otherwise technically flawless procedure. Experience has identifie...

journal_title：Current cardiology reports

authors： Dewey TM,Mack MJ

更新日期：1999-11-01 00:00:00

abstract：:Beta-Adrenergic blockade is associated with a significant reduction in mortality in most patients with structural heart disease. Clinical trial data involving patients after myocardial infarction or with congestive heart failure demonstrate that a reduction in sudden death accounts for much of the observed mortality r...

journal_title：Current cardiology reports

authors： Reiter MJ

更新日期：2002-09-01 00:00:00

abstract：:Despite a vast body of research on antithrombotic therapy for patients with cardiac disease, there are few clinical settings where robust evidence of their benefit exists. Patients with heart failure often have vascular disease and atrial fibrillation contributing to their poor prognosis. For patients with heart failu...

journal_title：Current cardiology reports

authors： Cleland JG,Mumtaz S,Cecchini L

更新日期：2012-06-01 00:00:00

abstract：:Aortic stenosis is a common valvular abnormality. Surgical valve replacement is the standard of care for symptomatic patients with severe aortic stenosis and is appropriate for certain asymptomatic patients. Statin therapy may slow progression of the disease. Contrary to conventional wisdom, vasodilator therapy may in...

journal_title：Current cardiology reports

authors： Botkin NF,Aurigemma GP

更新日期：2004-03-01 00:00:00

abstract：:Recurrent pericarditis is one of the most troublesome complications of pericarditis occurring in about one third of patients with a previous attack of pericarditis. The pathogenesis is presumed to be autoimmune and/or autoinflammatory in most cases. The mainstay of therapy for recurrences is physical restriction and a...

journal_title：Current cardiology reports

authors： Imazio M,Adler Y,Charron P

更新日期：2016-06-01 00:00:00

abstract：:Synthesized as an antianginal compound 40 years ago, amiodarone has emerged as a uniquely effective antiarrhythmic compound in recent years. It has numerous properties, the most prominent being the ability to lengthen repolarization in the atria and ventricles associated with bradycardia without the significant potent...

journal_title：Current cardiology reports

authors： Singh BN

更新日期：2006-09-01 00:00:00

abstract：:Although overall stroke incidence has been declining in developed countries, there is evidence that stroke in the young is increasing. Increasing incidence may be particularly pronounced among minorities in whom historically a higher burden of stroke has been reported. Compared with older adults, time spent with disab...

journal_title：Current cardiology reports

authors： Sultan S,Elkind MS

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Moderate or severe aortic regurgitation (AR) occurs in 0.5% of the population and typically peaks in the fourth to sixth decade of life. A significant proportion of patients have prohibitive surgical risk and are therefore treated medically with pharmacological management of heart failure and no d...

journal_title：Current cardiology reports

authors： Markham R,Ghodsian M,Sharma R

更新日期：2020-07-28 00:00:00

abstract：:A number of reports demonstrate the importance of serum triglyceride values in predicting the clinical onset of vascular disease. However, adjustment for measurements highly correlated with triglyceride (TG) levels, such as history of diabetes, body mass index, and high-density lipoprotein cholesterol (HDL-C), lessen ...

journal_title：Current cardiology reports

authors： Sprecher DL

更新日期：2001-09-01 00:00:00

abstract：:Selective coronary angiography was originally performed through open brachial arteriotomy. Thereafter, the percutaneous Seldinger technique and the use of preformed Judkins-type catheters popularized the femoral approach. More recently, after the first report of successful coronary angiography by the transradial appro...

journal_title：Current cardiology reports

authors： Franchi E,Marino P,Biondi-Zoccai GG,De Luca G,Vassanelli C,Agostoni P

更新日期：2009-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The goal of this paper is to review present knowledge regarding biological pacemakers created by somatic reprogramming as a platform for mechanistic and metabolic understanding of the rare subpopulation of pacemaker cells, with the ultimate goal of creating biological alternatives to electronic pacing...

journal_title：Current cardiology reports

authors： Xiao A,Cho HC

更新日期：2020-03-30 00:00:00

abstract：:Low serum levels of high-density lipoprotein cholesterol (HDL-C) are highly prevalent and are recognized as an independent risk factor for cardiovascular morbidity (myocardial infarction, stroke, peripheral arterial disease, and restenosis after coronary stenting) and mortality. HDL plays an important role in modulati...

journal_title：Current cardiology reports

authors： Toth PP

更新日期：2008-11-01 00:00:00

abstract：:Despite the critical importance of plasma lipoproteins in the development of atherosclerosis, varying degrees of evidence surround the causal associations of lipoproteins with coronary artery disease (CAD). These causal contributions can be assessed by employing genetic variants as unbiased proxies for lipid levels. A...

journal_title：Current cardiology reports

authors： Keenan TE,Rader DJ

更新日期：2013-09-01 00:00:00

abstract：:Imaging with radionuclides has historically played an important role in detection of cardiovascular disease as well as in risk stratification and prognostication. With the growth of molecular biology have come new therapeutic interventions and the requirement for new diagnostic imaging approaches. Noninvasive targeted...

journal_title：Current cardiology reports

authors： Dobrucki LW,Sinusas AJ

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are commonly used anti-hypertensive medications in a number of clinical settings. They are often used interchangeably, but we pose the provocative question as to whether they should be. We review the literature to evaluate for ...

journal_title：Current cardiology reports

authors： Turner JM,Kodali R

更新日期：2020-07-09 00:00:00

abstract：:Atherosclerosis is the proximate cause of arterial thrombosis, leading to acute occlusive cardiovascular syndromes. Thrombosis in atherosclerosis usually results from rupture of the fibrous cap of atherosclerotic plaques with a smaller proportion resulting from superficial endothelial erosion. Ruptured plaques are oft...

journal_title：Current cardiology reports

authors： Shah PK

更新日期：2014-12-01 00:00:00

abstract：:A number of neurohormones and cytokines are activated in heart failure and their activity is related to the progression of heart failure. Inhibiting the deleterious effects of the activated sympathetic and the renin-angiotensin-aldosterone systems with b-blockers, angiotensin-converting enzyme inhibitors, and aldoster...

journal_title：Current cardiology reports

authors： Anand IS

更新日期：2004-05-01 00:00:00

abstract：:Shared decision-making, central to evidence-based medicine and good patient care, begins and ends with the patient. It is the process by which a clinician and a patient jointly make a health decision after discussing options, potential benefits and harms, and considering the patient's values and preferences. Patient e...

journal_title：Current cardiology reports

authors： Kambhampati S,Ashvetiya T,Stone NJ,Blumenthal RS,Martin SS

更新日期：2016-05-01 00:00:00

abstract：:The feasibility and safety of transradial coronary intervention was demonstrated soon after the description of the transfemoral approach, despite which the use of the femoral artery still dominates in acute coronary syndrome intervention. The advantages of using the radial artery are virtual elimination of access site...

journal_title：Current cardiology reports

authors： Routledge H,Sastry S

更新日期：2015-12-01 00:00:00

abstract：:Over the past two decades, we have witnessed a large decrease in the death and complication rate of patients experiencing acute myocardial infarction (MI), due to our ability to restore blood flow to infarct-related arteries. Therapies include strategies to inhibit platelet function and induce fibrinolysis, and mechan...

journal_title：Current cardiology reports

authors： Maranian AM,Steinhubl SR

更新日期：2002-07-01 00:00:00

abstract：:Despite recent favorable trends in survival, heart failure remains a highly fatal disease. Improvements in the prevention of early death from coronary artery disease, along with an aging population, have resulted in an increased prevalence for heart failure in the United States. In the management of patients with hear...

journal_title：Current cardiology reports

authors： Feingold AD,DeNofrio D

更新日期：2003-05-01 00:00:00

abstract：:Statins are first line therapy for the prevention of cardiovascular disease (CVD). Only 30 %-70 % of high risk patients will attain standard low-density lipoprotein cholesterol targets. Patients with familial hypercholesterolemia and genetic mixed hyperlipidemias do not meet goals with standard therapy. Patients with ...

journal_title：Current cardiology reports

authors： Barnett J,Viljoen A,Wierzbicki AS

更新日期：2013-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To create awareness for the devastating influence of high cholesterol in familial hypercholesterolaemia (FH) on vessel walls. Persons with high LDL-C and a known mutation associated with FH have a 22-fold increase in CVD compared with those with a normal LDL-C and no genetic mutation. If the awareness...

journal_title：Current cardiology reports

authors： Wiegman A

更新日期：2018-08-09 00:00:00

abstract：:Understanding the genetic risk factors for stroke is an essential step to decipher the underlying mechanisms, facilitate the identification of novel therapeutic targets, and optimize the design of prevention strategies. A very small proportion of strokes are attributable to monogenic conditions, the vast majority bein...

journal_title：Current cardiology reports

authors： Chauhan G,Debette S

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize lifestyle interventions including pharmacological and non-pharmacological methods targeting modifiable risk factors and their impact on the future cardiovascular events in patients who have suffered transient ischemic attack (TIA) and/or ischemic stroke (IS). RECENT FINDINGS:The latest r...

journal_title：Current cardiology reports

authors： Vellipuram AR,Rodriguez G,Rawla P,Maud A,Cruz-Flores S,Khatri R

更新日期：2019-04-22 00:00:00

abstract：:Innate differences in gender physiology result in unique exposures, risk, and protection that are specific to women. Recognition and appreciation of these differences results in better treatment adaptations for women and better outcomes. Disparities between genders in the treatment of major cardiovascular risk factors...

journal_title：Current cardiology reports

authors： Jarvie JL,Foody JM

更新日期：2010-11-01 00:00:00

abstract：:Periprocedural thromboembolic and hemorrhagic events are complications of percutaneous radiofrequency catheter ablation (RFA) of atrial fibrillation (AF). The management of anticoagulation before and after RFA could play an important role in the prevention of these complications. The incidence of thromboembolic events...

journal_title：Current cardiology reports

authors： Viles-Gonzalez JF,Mehta D

更新日期：2011-02-01 00:00:00

abstract：:Plasminogen activation potential in the blood is controlled by an equilibrium between plasminogen activators, mainly tissue-type plasminogen activator (t-PA), and inhibitors, mainly plasminogen activator inhibitor (PAI)-1. In cardiovascular practice, imbalance of this fibrinolytic potential is encountered primarily in...

journal_title：Current cardiology reports

authors： Juhan-Vague I,Morange P,Christine Alessi M

更新日期：1999-07-01 00:00:00

abstract：:Cardiac surgery (CS) with cardiopulmonary bypass (CPB) is currently the most common surgery in the United States. Understanding, avoiding, and preventing postoperative complications, including neurologic deficits following CS, represents a great public and economic benefit for society, especially considering our aging...

journal_title：Current cardiology reports

authors： Razumovsky AY,Gugino LD,Owen JH

更新日期：2006-02-01 00:00:00