解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Disorders of the pericardium are common and can result in significant morbidity and mortality. Advances in multimodality imaging have enhanced our ability to diagnose and stage pericardial disease and improve our understanding of the pathophysiology of the disease. Cardiovascular MRI (CMR) can be used to define perica...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2020.08.008
更新日期:2021-01-01 00:00:00
abstract::Classification of heart failure is based on the left ventricular ejection fraction (EF): preserved EF, midrange EF, and reduced EF. There remains an unmet need for further heart failure phenotyping of ventricular structure-function relationships. Because of high spatiotemporal resolution, cardiac magnetic resonance (C...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2020.08.001
更新日期:2021-01-01 00:00:00
abstract::Population health and population health management of patients with heart failure aim to identify all patients with the condition in a population, to characterize and risk stratify subgroups of patients, to improve care delivery by leveraging technology and data so providers can improve care coordination, to engage di...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2020.06.006
更新日期:2020-10-01 00:00:00
abstract::Acute myocardial infarction (AMI) results in significant changes in cardiac structure and functions, leading to left ventricular remodeling and subsequent systolic and diastolic dysfunction. To improve current approaches in diagnoses, treatments, and prevention of cardiovascular diseases, a better understanding of car...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2020.02.002
更新日期:2020-07-01 00:00:00
abstract::This article reviews treatment and management of common cardiovascular emergencies in critically ill patients, focusing on acute decompensated heart failure, cardiogenic shock, pulmonary embolism, and hypertensive crisis management with inotropes, vasopressors, diuretics, and antiarrhythmic drugs. Clinicians frequentl...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2019.11.001
更新日期:2020-04-01 00:00:00
abstract::Understanding the role of sex- and gender-related factors, when dealing with a global growing epidemic such as heart failure, is a much needed and unmet goal for health care providers and scientists in order to design targeted strategies, aimed at improving both clinical and patient reported outcomes measures in women...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2019.08.005
更新日期:2020-01-01 00:00:00
abstract::Hypertensive heart disease includes the development of diastolic dysfunction, left ventricular hypertrophy, and heart failure with preserved and reduced ejection fraction. The development of heart failure can occur because of complications of ischemic heart disease or from progression of diastolic dysfunction to heart...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2019.06.005
更新日期:2019-10-01 00:00:00
abstract::Diabetes is strongly associated with development of cardiovascular disease and poor cardiovascular outcomes. Management of hypertension reduces cardiovascular outcomes among patients with diabetes. Many studies have examined the benefits of various classes of antihypertensives among patients with diabetes. Based on th...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2019.06.008
更新日期:2019-10-01 00:00:00
abstract::Alterations in myocardial energy metabolism as demonstrated by magnetic resonance spectroscopy (MRS) are critically involved in heart failure development. 1H-MRS allows investigation of the role of myocardial lipid accumulation in the pathophysiology of heart failure. With 31P-MRS, the most useful parameter is the car...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2019.02.010
更新日期:2019-07-01 00:00:00
abstract::The cardiology community lacks a taxonomy to prioritize the origins of the complex myocardial pathology underlying heart failure. The key question, "Why does heart muscle fail?", remains unanswered. A large body of literature indicates that myocardial fibrosis represents a principal pathway mediating outcomes in heart...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2018.12.009
更新日期:2019-04-01 00:00:00
abstract::Treatment of patients with heart failure with reduced ejection fraction has evolved. Recently, a fully implantable remote hemodynamic monitoring sensor in the pulmonary artery was approved in the treatment of patients at risk of heart failure readmissions. Several novel devices designed to offload the left atrium by c...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2018.12.011
更新日期:2019-04-01 00:00:00
abstract::Atrial fibrillation often occurs as a cause or consequence of heart failure. Clinical outcomes are worse when atrial fibrillation and heart failure coexist. There are important sex-related differences in the incidence, prevalence, pathophysiology, treatment, and outcomes of these patients. Women with heart failure are...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2018.08.006
更新日期:2019-01-01 00:00:00
abstract::Ultrafiltration (UF) mechanically removes excess fluid volume through an extracorporeal circuit and has been applied to clinical situations in which volume removal is the mainstay of therapy. Because of this ability, UF serves as an enticing method to treat acute heart failure (AHF) in which most symptoms are driven b...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2018.06.013
更新日期:2018-10-01 00:00:00
abstract::Convergence of the fields of heart failure (HF) and interventional cardiology has led to the formation of a discipline referred to as interventional HF. Although the term may be applied to essentially any invasive procedure performed in patients with HF (eg, coronary angiography, percutaneous coronary intervention, in...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2018.06.007
更新日期:2018-10-01 00:00:00
abstract::Despite advances in targeted medical therapy, pulmonary arterial hypertension (PAH) remains a fatal disease because of progressive right ventricular dysfunction. For patients who are refractory to medical therapy, heart-lung and lung transplantation are important treatment options. Because of longer waiting time, surg...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2018.02.007
更新日期:2018-07-01 00:00:00
abstract::Valvular heart disease (VHD) is frequently accompanied by pulmonary hypertension (PH). In asymptomatic patients, PH is rare, although the exact prevalence is unknown and mainly stems from the severity of the VHD and the presence of diastolic dysfunction. PH can also be depicted during exercise echocardiography. PH eit...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2018.03.009
更新日期:2018-07-01 00:00:00
abstract::RASopathies are a heterogeneous group of genetic syndromes characterized by mutations in genes that regulate cellular processes, including proliferation, differentiation, survival, migration, and metabolism. Excluding congenital heart defects, hypertrophic cardiomyopathy is the most frequent cardiovascular defect in p...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2017.12.005
更新日期:2018-04-01 00:00:00
abstract::Adrenomedullin (AM) is a vasodilatory peptide originally discovered in human pheochromocytoma tissue. Although AM is highly expressed in the adrenal glands, heart, lungs, and kidneys, vascular endothelium and smooth muscle are thought to be the main source of plasma AM. The AM precursor is processed to AM-glycine, whi...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2017.08.006
更新日期:2018-01-01 00:00:00
abstract::The occurrence of cardiovascular events shows a different distribution during the week, with many studies reporting a Monday peak, possibly related to the role of stress associated with commencing weekly activities. Furthermore, a higher mortality has been observed among patients hospitalized for cardiovascular and ot...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2017.05.007
更新日期:2017-10-01 00:00:00
abstract::Positive inotropic drugs have long been studied for their potential benefits in patients with heart failure and reduced ejection fraction (HFrEF). Although there has been an extensive amount of research about the clinical effects of these drugs in general, few studies examined their effect in older patients. Therefore...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2017.02.008
更新日期:2017-07-01 00:00:00
abstract::Cardiovascular demands to the care of cancer patients are common and important given the implications for morbidity and mortality. As a consequence, interactions with cardiovascular disease specialists have intensified to the point of the development of a new discipline termed cardio-oncology. As an additional consequ...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2016.12.011
更新日期:2017-04-01 00:00:00
abstract::Both cardiac resynchronization therapy with a pacemaker (CRT-P) and with a biventricular implantable cardioverter-defibrillator (CRT-D) are electrical treatment modalities validated for the management of chronic heart failure. There is no strong scientific evidence that a CRT-D must be offered to all candidates. Commo...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2016.07.012
更新日期:2017-01-01 00:00:00
abstract::Dyssynchronous contraction of the ventricle significantly worsens morbidity and mortality in patients with heart failure (HF). Approximately one-third of patients with HF have cardiac dyssynchrony and are candidates for cardiac resynchronization therapy (CRT). The initial understanding of dyssynchrony and CRT was in t...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2016.07.003
更新日期:2017-01-01 00:00:00
abstract::Takotsubo syndrome (TTS) is an enigmatic disease with a multifactorial and still unresolved pathogenesis. A genetic predisposition has been suggested based on the few familial TTS cases. Conflicting results have been published regarding the role of functional polymorphisms in relevant candidate genes, such as α1-, β1-...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2016.06.007
更新日期:2016-10-01 00:00:00
abstract::Heart failure is a complex clinical syndrome. The natural history of this syndrome is progressive. Advanced heart failure is present when a patient has signs and symptoms of heart failure that are refractory to therapy. Patients with the most advanced disease and worst prognosis can be identified using iterative, inte...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2016.03.001
更新日期:2016-07-01 00:00:00
abstract::Adverse myocardial remodeling can be reversed by medical, surgical, and device therapies leading to reduced heart failure (HF) morbidity and mortality and significant improvements in the structure and function of the failing heart. The growing population of HF patients who experience a degree of myocardial improvement...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2016.03.007
更新日期:2016-07-01 00:00:00
abstract::As atrial fibrillation (AF) substantially increases the risk of stroke and other thromboembolic events, most AF patients require appropriate antithrombotic prophylaxis. Oral anticoagulation (OAC) with either dose-adjusted vitamin K antagonists (VKAs) (eg, warfarin) or non-VKA oral anticoagulants (eg, dabigatran, apixa...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2015.08.021
更新日期:2016-04-01 00:00:00
abstract::Coronary artery bypass grafting (CAGB) is superior to percutaneous coronary intervention (PCI) in reducing mortality in certain patients and improving the composite end points of angina, recurrent myocardial infarction, and repeat revascularization procedures. However, CABG is associated with a higher perioperative st...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2015.08.011
更新日期:2016-01-01 00:00:00
abstract::Prevalence and incidence of chronic heart failure (CHF) has increased during the past decades. Beyond its impact on mortality rates, CHF severely impairs quality of life, particularly with the elderly and vulnerable population. Several studies have shown that CHF takes its toll mostly on the uneducated, low-income pop...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2015.07.012
更新日期:2015-10-01 00:00:00
abstract::In-hospital worsening heart failure represents a clinical scenario wherein a patient hospitalized for acute heart failure experiences a worsening of their condition, requiring escalation of therapy. Worsening heart failure is associated with worse in-hospital and postdischarge outcomes. Worsening heart failure is incr...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2015.07.004
更新日期:2015-10-01 00:00:00
abstract::The estimated cost of treating patients with HF in the United States is expected to more than double by 2030.65 This forecast of the impact of HF in the United States should serve as a call to action. Despite well-documented benefits, participation in exercise training and CR programs by patients with HF remains low. ...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2015.03.007
更新日期:2015-07-01 00:00:00
abstract::Coronary revascularization to improve left ventricular (LV) function and improve mortality in patients with ischemic cardiomyopathy remains controversial, especially in the absence of angina or ischemia. A large body of observational evidence suggests that patients with dysfunctional but viable myocardium may experien...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2014.12.002
更新日期:2015-04-01 00:00:00
abstract::One of the primary hallmarks of patients diagnosed with heart failure (HF) is a reduced tolerance to exercise and compromised functional capacity. This limitation stems from poor pumping capacity but also major changes in functioning of the vasculature, skeletal muscle, and respiratory systems. Advances in the underst...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2014.08.009
更新日期:2015-01-01 00:00:00
abstract::Heart failure (HF) is a clinical syndrome of breathlessness, lower extremity swelling, fatigue, and exercise intolerance affecting a large portion of the population worldwide, and associated with premature death. Despite improvement in the management of HF, many patients remain unable to complete activities of daily l...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2014.08.005
更新日期:2015-01-01 00:00:00
abstract::The central roles of neurohormonal abnormalities in the pathobiology of heart failure have been defined in recent decades. Experiments have revealed both systemic involvement and intricate subcellular regulation by circulating effectors of the sympathetic nervous system, the renin-angiotensin-aldosterone system, and o...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2014.07.002
更新日期:2014-10-01 00:00:00
abstract::Heart failure with preserved ejection fraction (HFPEF) is a common subtype of heart failure with morbidity and mortality similar to that of heart failure with systolic dysfunction. This article discusses the numerous biomarkers that promise to play a substantial role in terms of our ability to understand the mechanism...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2014.04.005
更新日期:2014-07-01 00:00:00
abstract::Rheumatic diseases are associated with an increased risk of cardiovascular (CV) mortality attributed to a higher incidence of heart failure (HF) and ischemic heart disease. Although traditional CV risk factors contribute to the increased incidence seen in this population, by themselves they do not account for the incr...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2013.10.003
更新日期:2014-04-01 00:00:00
abstract::Blood-pump miniaturization has made amazing progress, reducing the pump diameter to one-tenth of the size of previous positive displacement pumps. In particular, axial-flow-pump technology allows tiny pumps running at high speeds to deliver from 2 to 10 L/min. A review of the background inventions of the Jarvik 2000 t...
journal_title:Heart failure clinics
pub_type: 杂志文章,评审
doi:10.1016/j.hfc.2013.09.002
更新日期:2014-01-01 00:00:00
abstract::The impact of lifelong exposure to myocardial dysfunction in populations with congenital heart disease (CHD) is becoming increasingly recognized. Most children born with CHD now reach adulthood and the long-term sequelae of treatment are contributing to substantial comorbidity. The combination of structural changes pr...
journal_title:Heart failure clinics
pub_type: 杂志文章
doi:10.1016/j.hfc.2013.09.008
更新日期:2014-01-01 00:00:00
abstract::The tricuspid valve is frequently affected in adults with congenital heart disease but is also frequently overlooked. Disease of this valve can occur primarily or develop secondary to changes in the right ventricle caused by other disease states. The embryology and anatomy of the tricuspid valve are important to under...
journal_title:Heart failure clinics
pub_type: 杂志文章
doi:10.1016/j.hfc.2013.09.019
更新日期:2014-01-01 00:00:00