abstract：:Progenitor cells of the human erythroid and granulocytic cell lineages are characterized by the presence of several nucleoli. One of these nucleoli is larger and possesses more fibrillar centres than others. Such nucleolus is apparently dominant in respect of both size and main nucleolar function such as nucleolar-rib...

journal_title：Folia biologica

authors： Smetana K,Klamová H,Mikulenková D

更新日期：2020-01-01 00:00:00

abstract：:Hypothermic incubation of chicken eggs leads to smaller embryos with enlarged hearts, originally described as hypertrophic. Over the years, however, accumulated evidence suggested that hyperplasia, rather than hypertrophy, is the predominant mechanism of cardiac growth during the prenatal period. We have thus set to r...

journal_title：Folia biologica

authors： Skuhrová K,Kvasilová A,Svatůňková J,Sedmera D

更新日期：2019-01-01 00:00:00

abstract：:Steroid 5α-reductase type 3 congenital disorder of glycosylation (SRD5A3-CDG) is a severe metabolic disease manifesting as muscle hypotonia, developmental delay, cerebellar ataxia and ocular symptoms; typically, nystagmus and optic disc pallor. Recently, early onset retinal dystrophy has been reported as an additional...

journal_title：Folia biologica

authors： Kousal B,Honzík T,Hansíková H,Ondrušková N,Čechová A,Tesařová M,Stránecký V,Meliška M,Michaelides M,Lišková P

更新日期：2019-01-01 00:00:00

abstract：:The pathogenic molecular mechanisms underlying the insurgence of nasal polyps has not been completely defined. In some patients, these lesions can have a recurrence after surgery removal, and the difference between recurrent and not recurrent patients is still unclear. To molecularly characterize and distinguish betwe...

journal_title：Folia biologica

authors： Terrinoni A,Palombo R,Pitolli C,Caporali S,De Berardinis R,Ciccarone S,Lanzillotta A,Mauramati S,Porta G,Minieri M,Melino G,Bernardini S,Bruno E

更新日期：2019-01-01 00:00:00

abstract：:Autoimmune uveitis is a serious sightthreatening disease that in many cases fails to respond to conventional immunosuppressive or biological therapy. Experimental models used in research allow more detailed study of pathogenesis of the autoimmune process and testing new therapeutic strategies. Recent results show that...

journal_title：Folia biologica

authors： Seidler Stangova P,Dusek O,Klimova A,Heissigerova J,Kucera T,Svozilkova P

更新日期：2019-01-01 00:00:00

abstract：:Activated platelets and glycated lipoproteins are responsible for atherothrombosis in diabetics. Melatonin and native high-density lipoproteins are crucial in the preservation of pro/oxidant-antioxidant balance. The aim of the present study was to investigate the in vitro effects of native high-density lipoproteins an...

journal_title：Folia biologica

authors： Ozsavci D,Nazli A,Bingol Ozakpinar O,Yanikkaya Demirel G,Vanizor Kural B,Sener A

更新日期：2018-01-01 00:00:00

abstract：:The existence of a restrained inflammatory state in schizophrenic individuals posed the question whether anti-inflammatory drugs may exert antipsychotic effects. Therefore, the effect of ibuprofen (IB) on cytokine production by human peripheral blood mononuclear cells (PBMC) from schizophrenic patients was examined an...

journal_title：Folia biologica

authors： Bessler H,Cohen-Terica D,Djaldetti M,Sirota P

更新日期：2017-01-01 00:00:00

abstract：:Formation and growth of atherosclerotic plaques have serious clinical consequences. One mechanism that occurs during atherogenesis is migration of smooth muscle cells from the middle layer of the artery to the intima, where they proliferate and are transformed into foam cells. This degenerative process is accompanied ...

journal_title：Folia biologica

authors： Kuzan A,Michel O,Gamian A

更新日期：2017-01-01 00:00:00

abstract：:Autosomal-dominant polycystic kidney disease (ADPKD) is an inherited disease that results in multiple kidney cysts, and it is a common cause of end-stage renal disease. Recent studies have shown that disease progression can be slowed by simultaneous disruption of the primary cilium and polycystins. The exact genetic m...

journal_title：Folia biologica

authors： Skalická K,Hrčková G,Vaská A,Baranyaiová A,Janega P,Žilinská Z,Daniš D,Kovács L

更新日期：2017-01-01 00:00:00

abstract：:The role of vitamin B6 as a key component in a number of biological events has been well established. Based on the relationship between chronic inflammation and carcinogenesis on the one hand, and the interaction between immune and cancer cells expressed by modulated cytokine production on the other hand, the aim of t...

journal_title：Folia biologica

authors： Bessler H,Djaldetti M

更新日期：2016-01-01 00:00:00

abstract：:The aim of this study was to evaluate wild boar (Sus scrofa scrofa) caecal and colon products of microbial activity including short chain fatty acids (SCFA), ammonia and methane concentrations. The in vitro method was applied to caecal and colon contents after 12 and 24-hour incubation with the substrate (wheat bran),...

journal_title：Folia biologica

authors： Pecka-Kiełb E,Bujok J,Miśta D,Króliczewska B,Górecka J,Zawadzki W

更新日期：2016-01-01 00:00:00

abstract：:Mucopolysaccharidosis type II (MPS II) is an X-linked lysosomal storage disorder resulting from deficiency of iduronate-2-sulphatase activity. The disease manifests almost exclusively in males; only 16 symptomatic heterozygote girls have been reported so far. We describe the results of X-chromosome inactivation analys...

journal_title：Folia biologica

authors： Řeboun M,Rybová J,Dobrovolný R,Včelák J,Veselková T,Štorkánová G,Mušálková D,Hřebíček M,Ledvinová J,Magner M,Zeman J,Pešková K,Dvořáková L

更新日期：2016-01-01 00:00:00

abstract：:Epigenetic changes are considered to be a frequent event during tumour development. Hypermethylation of promoter CpG islands represents an alternative mechanism for inactivation of tumour suppressor genes, DNA repair genes, cell cycle regulators and transcription factors. The aim of this study was to investigate promo...

journal_title：Folia biologica

authors： Chmelařová M,Sirák I,Mžik M,Sieglová K,Vošmiková H,Dundr P,Němejcová K,Michálek J,Vošmik M,Palička V,Laco J

更新日期：2016-01-01 00:00:00

abstract：:Bile acids have been implicated in cholestatic liver damage, primarily due to their detergent effect on membranes and induction of oxidative stress. Gangliosides can counteract these harmful effects by increasing the rigidity of the cytoplasmic membrane. Induction of haem oxygenase (HMOX) has been shown to protect the...

journal_title：Folia biologica

authors： Šmíd V,Petr T,Váňová K,Jašprová J,Šuk J,Vítek L,Šmíd F,Muchová L

更新日期：2016-01-01 00:00:00

abstract：:Among various strategies employed for spinal cord injury, stem cell therapy is a potential treatment. So far, a variety of stem cells have been evaluated in animal models and humans with spinal cord injury, and epidermal neural crest stem cells represent one of the attractive types in this area. Although these multipo...

journal_title：Folia biologica

authors： Pandamooz S,Salehi MS,Nabiuni M,Dargahi L,Pourghasem M

更新日期：2016-01-01 00:00:00

abstract：:The sister chromatid exchange test is regarded as a highly sensitive cytogenetic assay. It measures chromosome sensitivity to particular damage factors and provides information on control and repair mechanism performance. It is instrumental in the early identification of the effects of noxious factors present in the h...

journal_title：Folia biologica

authors： Kuchta-Gładysz M,Wójcik E,Szeleszczuk O,Niedbała P,Wojnar T

更新日期：2016-01-01 00:00:00

abstract：:The tissue factor (TF) - tissue factor pathway inhibitor (TFPI) axis plays a major role in hemostasis. Disorders of the coagulation system are commonly diagnosed with the help of screening tests such as prothrombin time (PT), activated partial thromboplastin time (aPTT), and plasma fibrinogen concentration (PFC). Howe...

journal_title：Folia biologica

authors： Buzala M,Ponczek MB,Slomka A,Roslewska A,Janicki B,Zekanowska E,Bednarczyk M

更新日期：2016-01-01 00:00:00

abstract：:The aim of the study was to compare muscle fibre parameters and quality of m. seninembranosus in pigs. The experiment was conducted with 18 Pulawska pigs, 24 Polish Large White (PLW) pigs, and 24 Pietrain pigs slaughtered at 105 kg body weight. The results obtained indicate that the breed of pigs has a significant eff...

journal_title：Folia biologica

authors： Wojtysiak D,Gorska M,Wojciechowska J

更新日期：2016-01-01 00:00:00

abstract：:Alteration in microRNA-146a (miRNA-146a) expression is an important event in the pathogenesis of many human diseases. MiRNA-146a rs2910164 is a functional polymorphism that showed association with several diseases. Metabolic syndrome is an aggregation of multiple risk factors including impaired glucose tolerance, incr...

journal_title：Folia biologica

authors： Mehanna ET,Ghattas MH,Mesbah NM,Saleh SM,Abo-Elmatty DM

更新日期：2015-01-01 00:00:00

abstract：:In this study an attempt was made to analyse morphological changes in sperm with particular attention to sperm with a cytoplasmic droplet, taking into account the age and breed of the boar. The material for the study consisted of ejaculates of insemination boars of five breeds. Morphological examination of sperm was c...

journal_title：Folia biologica

authors： Banaszewska D,Biesiada-Drzazga B,Andraszek K

更新日期：2015-01-01 00:00:00

abstract：:The European perch is a species endowed with high adaptation capabilities as regards different environmental conditions. The aim of the study was to analyse the annual developmental cycle of ovaries of the European perch from the Oder river, Lake Dąbie and a drainage canal (Warm Canal) carrying post-cooling water from...

journal_title：Folia biologica

authors： Kirczuk L,Domagała J,Pilecka-Rapacz M

更新日期：2015-01-01 00:00:00

abstract：:Gametogenesis and the temporal changes occurring in the ovaries and testes throughout the reproductive cycle in the invasive alien bivalve, Chinese pond mussel Sinanodonta woodiana (Lea), from the heated Konin lakes system (central Poland) were studied using histological techniques. S. woodiana was confirmed to be a g...

journal_title：Folia biologica

authors： Hliwa P,Zdanowski B,Dietrich GJ,Andronowska A,Król J,Ciereszko A

更新日期：2015-01-01 00:00:00

abstract：:We use analysis of mitochondrial DNA barcodes in combination with published data on morphology to rearrange the taxonomy of two arctic species, Gynaephora groenlandica and G. rossii. We demonstrate that (1) the taxon lugens Kozhanchikov, 1948 originally described as a distinct species is a subspecies of Gynaephora ros...

journal_title：Folia biologica

authors： Lukhtanov VA,Khruleva OA

更新日期：2015-01-01 00:00:00

abstract：:Benzoic acid (BA) and citric acid (CA) are food additives commonly used in many food products. Food additives play an important role in food supply but they can cause various harmful effects. The in vitro adverse effects of BA and CA and the protective effect of quercetin on human erythrocytes were investigated by mea...

journal_title：Folia biologica

authors： Baş H,Kalender S,Pandir D

更新日期：2014-01-01 00:00:00

abstract：:The incidence of allergic diseases is steadily increasing an urgent need to clarify the immunologic processes which occur early in life and signal an increased risk of possible future allergy development. The ratio and maturation state of DCs together with the cytokine environment are important in directing and modula...

journal_title：Folia biologica

authors： Hrdý J,Novotná O,Kocourková I,Prokešová L

更新日期：2014-01-01 00:00:00

abstract：:The objective of this study was to assess the utility of the magnetic-activated cell sorting (MACS) technique used for improving characteristics and quality of insemination doses by the elimination ofapoptotic rabbit spermatozoa from a heterospermic pool (Experiment 1) as well as from the ejaculates of individual buck...

journal_title：Folia biologica

authors： Vasicek J,Pivko J,Chrenek P

更新日期：2014-01-01 00:00:00

abstract：:Responses of adipose cells to adrenoceptor regulation, including that of β-adrenoceptor (AR), and the signalling machinery involved in these responses are not sufficiently understood; information that is helpful for elucidating the adrenoceptor (adrenergic and β-AR)-responsive machinery is insufficient. We examined ph...

journal_title：Folia biologica

authors： Ohsaka Y,Nishino H,Nomura Y

更新日期：2014-01-01 00:00:00

abstract：:The compensation of cell motion is an important step in single-particle tracking analysis of live cells. This step is required in most of the cases, since the movement of subcellular foci is superimposed by the movement and deformation of the cell, while only the local motion of the foci is important to be analysed. T...

journal_title：Folia biologica

authors： Sorokin DV,Suchánková J,Bártová E,Matula P

更新日期：2014-01-01 00:00:00

abstract：:The development of the follicular wall and apoptosis of corresponding cells are dependent upon the stage of follicle growth and levels of endogenous hormones. However, the development and apoptosis of prehierarchical follicles in geese is insufficiently known. In order to obtain an understanding about the microstructu...

journal_title：Folia biologica

authors： Dong X,Liu HH,Wang JW,Xiao QH,Yuan X,Li L,Xia L,Li L

更新日期：2014-01-01 00:00:00

abstract：:Understanding mortality patterns and interactions between entomopathogenic fungi and parasitoids is important to improve insect biological control programs. The aim of this study was to evaluate the effect of Metarhizium anisopliae (Metschnikoff, 1879) Sorokin, 1833 and Beauveria bassiana (Balsamo) Vuillemin, 1912 (Hy...

journal_title：Folia biologica

authors： Rossoni C,Loureiro Ede S,Pereira FF,Kassab SO,Costa DP,Barbosa RH

更新日期：2014-01-01 00:00:00

abstract：:Recently developed techniques of DNA barcoding and next-generation sequencing (NGS) overcome previous limitations of evaluation of animal diet composition and together are promising method in molecular ecology. The objective was to compare standard ABI Sanger sequencing with new high throughput sequencing (Illumina Mi...

journal_title：Folia biologica

authors： Kajtoch Ł

更新日期：2014-01-01 00:00:00

abstract：:Podoplanin, D2-40, has been described in a variety of normal and neoplastic tissues. It is often used for highlighting lymphatics. We evaluated the expression of podoplanin in α-smooth muscle actinpositive myofibroblasts producing the suburothelial layer in tunica propria of the urinary bladder that have some similar ...

journal_title：Folia biologica

authors： Povýšil C,Kaňa M,Zámečník L,Vaľová Z,Hanuš T

更新日期：2014-01-01 00:00:00

abstract：:In human, autoimmune uveitis is a leading cause of visual disability and ranks with diabetic retinopathy as a major source of blind registrations in developed countries. Since most cases of non-infectious uveitis are considered to be autoimmune or at least immune-mediated, the management of such patients has rested on...

journal_title：Folia biologica

authors： Klímová A,Seidler Štanogová P,Heissigerová J,Svozílková P,Kučera T

更新日期：2014-01-01 00:00:00

abstract：:The patterns of sperm formation in sternorrhynchous jumping plant-lice are reviewed. To date information is available for 143 species belonging to 54 genera, 17 subfamilies and seven of the eight psylloid families (only Phacopteronidae is not represented). For the majority of the taxa (116 species, 39 genera, 10 subfa...

journal_title：Folia biologica

authors： Labina ES,Maryańska-Nadachowska A,Burckhardt D,Kuznetsova VG

更新日期：2014-01-01 00:00:00

abstract：:Mafosfamide cyclohexylamine salt (D-17272), 4-hydro-peroxy-cyclophosphamide (D-18864) and glufosfamide (D-19575, beta-D-glucose-isophosphoramide mustard) are new generation oxazaphosphorine agents. The present investigation was undertaken to determine the activity of these three oxazaphosphorines in human promyelocyti...

journal_title：Folia biologica

authors： Mazur L,Opydo-Chanek M,Stojak M,Niemeyer U

更新日期：2013-01-01 00:00:00

abstract：:The effect of quercetin was studied on the multi-eyed flatworm Polycelis felina (Daly.) in laboratory conditions. This is a very suitable test-organism available year-round in nature, easily maintained in the laboratory. The results showed that depending on the dose and recovery period quercetin caused locomotory (beh...

journal_title：Folia biologica

authors： Rajević N,Matković H,Gregorović G,Kovacević G,Knezović L,Kalafatić M

更新日期：2013-01-01 00:00:00

abstract：:Genome-wide association studies have revealed several gene variants associated with obesity; however, only a few studies have further investigated their association with metabolic syndrome. We performed a study of eleven variants in/near genes TMEM18, SH2B1, KCTD15, PCSK1, BDNF, SEC16B, MC4R, and FTO in Czech adolesce...

journal_title：Folia biologica

authors： Dušátková L,Zamrazilová H,Sedláčková B,Včelák J,Hlavatý P,Aldhoon Hainerová I,Korenková V,Bradnová O,Bendlová B,Kunešová M,Hainer V

更新日期：2013-01-01 00:00:00

abstract：:The organization of autonomic nerve structures in the large intestine of chinchilla was investigated using histochemical and immunocytochemical methods. The myenteric plexus formed network nodes of cholinergic neurocyte agglomerations connected with bundles of nerve fibres and localized between the circular and longit...

journal_title：Folia biologica

authors： Nowak E

更新日期：2013-01-01 00:00:00

abstract：:The gammadeltaT cells were identified as positive as well as negative regulators of immune responses. They take part in pathogen clearance, modulation of innate and adaptive immunity as well as in healing and tissue maintenance. The course of many pathological conditions such as collagen induced arthritis (CIA), exper...

journal_title：Folia biologica

authors： Strzepa A,Majewska-Szczepanik M,Szczepanik M

更新日期：2013-01-01 00:00:00

abstract：:Among the environmental chemicals which disturb endocrine functions, dioxins and polychlorinated biphenyls (PCBs) are known as the most toxic. Numerous studies in mammals revealed that dioxins and PCBs disrupt functions of the uterus, delay implantation and increase embryo loss. The direct effect of these chemicals on...

journal_title：Folia biologica

authors： Hrabia A,Leśniak A,Sechman A

更新日期：2013-01-01 00:00:00