听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览Frontiers of Hormone Research期刊下所有文献
  • Endocrinology of Hirsutism: From Androgens to Androgen Excess Disorders.

    abstract::Unwanted sexual hair growth has a considerable negative impact on a woman's self-esteem and quality of life. Excessive growth of terminal hair in women in a man-like pattern is defined as hirsutism and affects up to 1 in 7 women. Androgens secreted by the ovary and adrenal are the main regulator of physiological and p...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000494907

    authors: Yilmaz B,Yildiz BO

    更新日期:2019-01-01 00:00:00

  • Clinical Presentation of Hypoparathyroidism.

    abstract::Parathyroid hormone (PTH) is one of the major hormones that regulates serum calcium. Hypoparathyroidism occurs when PTH secretion is insufficient. The main symptoms of hypoparathyroidism are the result of low blood calcium levels, hypocalcemia, which interferes with normal muscle contraction and nerve conduction. As a...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000491044

    authors: Giusti F,Brandi ML

    更新日期:2019-01-01 00:00:00

  • Conventional Treatment of Hypoparathyroidism.

    abstract::The treatment of hypoparathyroidism depends on the severity of hypocalcemia, how rapidly the hypocalcemia developed, and the symptomatology. Chronic hypoparathyroidism is usually treated with oral supplementations, including calcium, calcitriol, or other active vitamin D analogs, and at times, thiazide diuretics. Alth...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000491046

    authors: Marcucci G,Brandi ML

    更新日期:2019-01-01 00:00:00

  • Metabolic Syndrome in Polycystic Ovary Syndrome.

    abstract::Both prevalence and incidence of the metabolic syndrome is very high in women with polycystic ovary syndrome (PCOS). Obesity and visceral fat enlargement play a dominant role in determining the final phenotype of PCOS. Androgen excess and insulin resistance may be responsible for the development of all features of the...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000485995

    authors: Pasquali R

    更新日期:2018-01-01 00:00:00

  • Metabolic Syndrome in Thyroid Disease.

    abstract::Cardiometabolic risk factors like abdominal obesity, hyperglycemia, low high-density lipoprotein (HDL) cholesterol, elevated triglycerides, and hypertension are defined as metabolic syndrome (MetS), which represents one of the most frequent endocrine disorders particularly in a society with increasing weight problems....

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000485996

    authors: Iwen KA,Oelkrug R,Kalscheuer H,Brabant G

    更新日期:2018-01-01 00:00:00

  • Intrahypophyseal Immune-Endocrine Interactions: Endocrine Integration of the Inflammatory Inputs.

    abstract::Endotoxin (lipopolysaccharide, LPS) of gram-negative bacteria has been recognized for more than 40 years as a modulator of anterior pituitary hormone production. The action of LPS was thought to be predominantly mediated through LPS-stimulated immune cell-derived cytokines, and is part of the concept of immune-endocri...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000452904

    authors: Renner U,Sapochnik M,Lucia K,Stalla GK,Arzt E

    更新日期:2017-01-01 00:00:00

  • Endocrine Immunology of Chagas Disease.

    abstract::The concept of immunoendocrine interactions, existing in normal and pathological conditions, is relatively recent. Accordingly, cells from the immune system and from endocrine glands share common receptors for cytokines and hormones, allowing systemic and local regulatory mechanisms. In this context, lymphoid organs a...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000452914

    authors: Savino W

    更新日期:2017-01-01 00:00:00

  • Hybrid Molecular Imaging in Differentiated Thyroid Carcinoma.

    abstract::Radioactive isotopes of radioiodine are frequently used in differentiated thyroid carcinoma (DTC) both for diagnosis and therapy. Their accumulation in thyroid cancer tissue is dependent on the expression and activity of the sodium-iodide symporter (NIS). Scintigraphic imaging using either planar or single-photon emis...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000442276

    authors: Schmidt D,Kuwert T

    更新日期:2016-01-01 00:00:00

  • Adrenal Molecular Imaging.

    abstract::The major workload in the field of adrenal imaging comprises patients with adrenal tumors incidentally depicted by imaging performed for other reasons than adrenal disease. These so-called 'incidentalomas' are generally managed by CT and MRI, and molecular imaging techniques are required only for a few patients. PET/C...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000442317

    authors: Sundin A

    更新日期:2016-01-01 00:00:00

  • Gastrointestinal Surgery of Neuroendocrine Neoplasms.

    abstract::Surgery is the only treatment that may cure the patient with gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) and should always be considered as the first-line treatment if radical resection can be achieved. Even in cases where radical surgery is not possible, palliative resection may be performed to reduc...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000382144

    authors: Hansen CP,Olsen IH,Knigge U

    更新日期:2015-01-01 00:00:00

  • Gut sweet taste receptors and their role in metabolism.

    abstract::Obesity is caused by an imbalance between food intake and energy expenditure. In recent decades the gastrointestinal tract has received growing attention as a control parameter for the regulation of appetite and food intake, however regulatory circuits and their interactions are complex. The basic understanding on the...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000358321

    authors: Meyer-Gerspach AC,Wölnerhanssen B,Beglinger C

    更新日期:2014-01-01 00:00:00

  • Adipose tissue dysfunction and inflammation in cardiovascular disease.

    abstract::Adipose tissue (AT) was long perceived as a passive lipid storage depot but it is now considered as an endocrine organ that produces a large number of mediators that affect metabolism, inflammation and coagulation. In obesity, the increased size of adipocytes and chronic low-grade inflammation within AT alter its norm...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000360560

    authors: Wronkowitz N,Romacho T,Sell H,Eckel J

    更新日期:2014-01-01 00:00:00

  • Infertility treatment in polycystic ovary syndrome: lifestyle interventions, medications and surgery.

    abstract::Management of patients with polycystic ovary syndrome (PCOS) who wish to become pregnant should include exclusion of other diseases in the woman and additional fertility disorders in the couple. Before the initiation of any pharmacological intervention, the importance of lifestyle modifications should be stressed, par...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章

    doi:10.1159/000341824

    authors: Panidis D,Tziomalos K,Papadakis E,Katsikis I

    更新日期:2013-01-01 00:00:00

  • Carney complex.

    abstract::Carney complex is a rare, dominantly inherited multiple endocrine neoplasia syndrome, affecting endocrine glands as the adrenal cortex (causing Cushing's syndrome), the pituitary and the thyroid. It is associated with many other nonendocrine tumors, including cardiac myxomas, testicular tumors, melanotic schwannoma, b...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000345669

    authors: Espiard S,Bertherat J

    更新日期:2013-01-01 00:00:00

  • Kallmann syndrome caused by mutations in the PROK2 and PROKR2 genes: pathophysiology and genotype-phenotype correlations.

    abstract::Mutations in the prokineticin 2 peptide (PROK2) and its seven-transmembrane domain type 2 receptor PROKR2 are newly identified molecular culprits in autosomal Kallmann syndrome (KS). Prok2 and prokr2 gene knockout mice both have agenesis or hypoplasia of the olfactory bulbs, associated with hypogonadotropic hypogonadi...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000312698

    authors: Sarfati J,Dodé C,Young J

    更新日期:2010-01-01 00:00:00

  • Molecular mechanisms of pituitary adenoma senescence.

    abstract::As commonly encountered pituitary adenomas are invariably benign, we examined protective pituitary proliferative mechanisms. Cellular senescence is characterized by a largely irreversible cell cycle arrest and constitutes a strong anti-proliferative response, which can be triggered by DNA damage, chromosomal instabili...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000318489

    authors: Chesnokova V,Zonis S,Ben-Shlomo A,Wawrowsky K,Melmed S

    更新日期:2010-01-01 00:00:00

  • Pituitary carcinomas.

    abstract::Pituitary carcinoma is a extremely rare and is characterized by a very poor prognosis. Even if at diagnosis the presence of metastases is required to define a pituitary carcinoma, the lesion was almost invariably diagnosed first as a benign pituitary tumor, that after a variable period of latency, ranging from few mon...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000318499

    authors: Colao A,Ochoa AS,Auriemma RS,Faggiano A,Pivonello R,Lombardi G

    更新日期:2010-01-01 00:00:00

  • Vasoinhibins and the pituitary gland.

    abstract::Vasoinhibins are a family of peptides that inhibit blood vessel growth, dilation, permeability, and survival. They are generated by the proteolytic cleavage of prolactin by cathepsin D, matrix metalloproteases, and bone morphogenic protein-1. Lactotropes within the anterior pituitary gland produce and release vasoinhi...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000318509

    authors: Méndez I,Vega C,Zamorano M,Moreno-Carranza B,Martínez de la Escalera G,Clapp C

    更新日期:2010-01-01 00:00:00

  • Testosterone in obesity, metabolic syndrome and type 2 diabetes.

    abstract::Testosterone levels are reduced in obesity, the metabolic syndrome and type 2 diabetes. Low testosterone levels are now being recognised as an independent risk factors for these conditions. Findings from men undergoing androgen suppression as treatment for prostate cancer confirm that the hypogonadal state increases b...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000176046

    authors: Stanworth R,Jones T

    更新日期:2009-01-01 00:00:00

  • Role of the endocannabinoid system in energy balance regulation and obesity.

    abstract::The endogenous cannabinoid system (ECS) is a neuromodulatory system recently recognized to have a role in the regulation of various aspects of eating behavior and energy balance through central and peripheral mechanisms. In the central nervous system, cannabinoid type 1 receptors and their endogenous ligands, the endo...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000115362

    authors: Cota D

    更新日期:2008-01-01 00:00:00

  • Bone morphogenetic protein-4 control of pituitary pathophysiology.

    abstract::Bone morphogenetic protein-4 (BMP-4), a member of the transforming growth factor-Beta(TGF-Beta) family, is overexpressed in different prolactinoma models and induces the development of these lineage adenomas. SMAD proteins activated by growth factors of the TGF-Beta and BMP family interact with estrogen receptors to s...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000094262

    authors: Giacomini D,Páez-Pereda M,Theodoropoulou M,Gerez J,Nagashima AC,Chervin A,Berner S,Labeur M,Refojo D,Renner U,Stalla GK,Arzt E

    更新日期:2006-01-01 00:00:00

  • Ectopic ACTH syndrome.

    abstract::Ectopic adrenocorticotropin secretion (EAS) accounts for 10-15% of cases of Cushing's syndrome and comprises a spectrum of tumours from undetectable isolated lesions to widespread metastatic and aggressive malignancies. EAS is often associated with severe hypercortisolaemia causing hypokalaemia, diabetes, generalized ...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000094323

    authors: Isidori AM,Kaltsas GA,Grossman AB

    更新日期:2006-01-01 00:00:00

  • Treatment of Cushing's disease: a retrospective clinical study of the latest 100 cases.

    abstract::We evaluate the current role of microsurgery for Cushing's disease (CD) and the efficacy of adjuvant treatment modalities. The standard treatment for primary CD remains transsphenoidal surgery followed by adjuvant therapy in cases with persisting hypercortisolism. Moderately severe cases are treated with radiotherapy,...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章

    doi:10.1159/000091580

    authors: Hofmann BM,Fahlbusch R

    更新日期:2006-01-01 00:00:00

  • Role of regulatory factors in pituitary tumour formation.

    abstract::The molecular basis of pituitary tumorigenesis remains controversial, but there are two major theories which have been subject to most investigation: hormonal (usually hypothalamic factors) and/or growth factor overstimulation, or a molecular defect within the pituitary itself. It has been shown, for example, that exc...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000079038

    authors: Korbonits M,Morris DG,Nanzer A,Kola B,Grossman AB

    更新日期:2004-01-01 00:00:00

  • Somatostatin receptors in pituitary function, diagnosis and therapy.

    abstract::Recent studies have demonstrated that human pituitary adenomas express multiple somatostatin receptor (sst) subtypes. The expression of sst subtypes in human pituitary adenomas is highly variable. This variability in sst subtype expression may explain the variable responsiveness of patients with pituitary adenomas to ...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章,评审

    doi:10.1159/000079048

    authors: Hofland LJ,Lamberts SW

    更新日期:2004-01-01 00:00:00

  • Uterine cancer and estrogen therapy.

    abstract::Recent studies concerning the relationship of exogenous estrogens and endometrial cancer have been reviewed, and the objections to their conclusions discussed. Even considering the most serious of these reservations, it is difficult to avoid the tentative conclusion that estrogens are causally linked to endometrial ca...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章

    doi:

    authors: Mack TM

    更新日期:1977-01-01 00:00:00

  • The effect of different regimens of oestrogens on the clotting and fibrinolytic system of the post-menopausal woman.

    abstract::The effects of six different regimens of hormone replacement therapy on coagulation, fibrinolysis and platelet aggregation were sudied in 33 symptomatic, post-menopausal women. Studies were performed before and after 3 months of therapy in the six treatment groups, Premarin, Progynova, Harmogen, Serial 28, ethynodiol ...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章

    doi:10.1159/000401994

    authors: Thom M,Dubiel M,Kakkar VV,Studd JW

    更新日期:1977-01-01 00:00:00

  • Clinical and experimental aspects of the anti-mammary carinogenic activity of estriol.

    abstract::Intermittent implantation of 600--1,300 microgram estriol subcutaneously beginning 48 h before oral administration of 7,12-dimethylbenz(a)anthracene or procarbazine prevents development of 80--90% of carcinomas of the breast occurring during the natural life span of the intact female Sprague-Dawley rat. Some estriol p...

    journal_title:Frontiers of hormone research

    pub_type: 杂志文章

    doi:10.1159/000401992

    authors: Lemon HM

    更新日期:1977-01-01 00:00:00