听力与言语-语言病理学

行为科学

医学伦理学

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  • Beyond Medical Treatment: Surgical Treatment of Gout.

    abstract:PURPOSE OF REVIEW:Medical treatment with urate-lowering therapy (ULT) is efficacious. A recent publication suggested that surgery in gout is more prevalent than previously reported. This revelation led us to review what is known about surgical treatment of gout. RECENT FINDINGS:The Google Scholar database (January 1, ...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-020-00969-6

    authors: Carcione J,Bodofsky S,LaMoreaux B,Schlesinger N

    更新日期:2020-11-24 00:00:00

  • Polymyalgia Rheumatica: a Common Disease in Seniors.

    abstract:PURPOSE OF THE REVIEW:Polymyalgia rheumatica (PMR) is one of the most common inflammatory rheumatologic condition occurring in older adults. It is characterized by proximal pain and stiffness in the shoulders, neck, and/or pelvic girdle in individuals over 50 years of age along with evidence of an intense systemic infl...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-020-00919-2

    authors: Gazitt T,Zisman D,Gardner G

    更新日期:2020-06-19 00:00:00

  • Vaccination for Children on Biologics.

    abstract:PURPOSE OF REVIEW:Several biologic drugs are available for treatment of immune-mediated diseases, and the number of children treated with biologics is increasing. This review summarises current knowledge about the safety and immunogenicity of vaccines in children treated with biologic therapy. RECENT FINDINGS:A recent...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-020-00905-8

    authors: Toplak N,Uziel Y

    更新日期:2020-05-20 00:00:00

  • Health-Related Quality of Life in Antiphospholipid Syndrome: Current Knowledge and Future Perspectives.

    abstract:PURPOSE OF REVIEW:Antiphospholipid syndrome (APS) is a chronic autoimmune disease that can be seen as a burden, with consequences on patients' daily life. Health has traditionally been measured using measures of morbidity or mortality. Health-related quality of life (HRQoL) is a concept that includes quality of life th...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-020-00900-z

    authors: Desnoyers M,Dufrost V,Wahl D,Zuily S

    更新日期:2020-05-13 00:00:00

  • The Challenges and Opportunities of Classifying Childhood Arthritis.

    abstract:PURPOSE OF REVIEW:Childhood arthritis is in need of a new system of classification, owing to deficiencies in the International League of Associations for Rheumatology (ILAR) criteria. We briefly review the history of classification of childhood arthritis, discuss the major criticisms of the current system, and highligh...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-020-0880-3

    authors: Rumsey DG,Laxer RM

    更新日期:2020-01-11 00:00:00

  • Arthritis in Idiopathic Inflammatory Myopathies.

    abstract:PURPOSE OF REVIEW:Arthritis is a well-recognized symptom of idiopathic inflammatory myopathies (IIM). We provide a summary of available data regarding the epidemiology, clinical characteristics, and autoantibody associations of joint involvement in various forms of IIM. RECENT FINDINGS:Arthritis is reported in 18-55% ...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-019-0878-x

    authors: Klein M,Mann H,Vencovský J

    更新日期:2019-12-07 00:00:00

  • Adipokines: New Therapeutic Target for Osteoarthritis?

    abstract:PURPOSE OF THE REVIEW:Osteoarthritis (OA) is an aging-associated and injury-induced joint disease characterized by cartilage degradation, bone sclerosis, and persistent low-grade inflammation in the joint. Aging and injury are triggers of joint pathological changes mediated by pro-inflammatory factors, some of which ar...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-019-0868-z

    authors: Xie C,Chen Q

    更新日期:2019-12-07 00:00:00

  • PET Scan: Nuclear Medicine Imaging in Myositis.

    abstract:PURPOSE OF REVIEW:Positron emission tomography (PET) combined with computed tomography (CT) has proven useful as a cancer screening technique in patients with inflammatory myopathy, mainly dermatomyositis. In this review, we focus on advances in this direction and other potential applications of PET/CT in patients with...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-019-0864-3

    authors: Selva-O'Callaghan A,Gil-Vila A,Simó-Perdigó M,Trallero-Araguás E,Alvarado-Cárdenas M,Pinal-Fernandez I

    更新日期:2019-11-21 00:00:00

  • Cardiovascular Safety of Urate Lowering Therapies.

    abstract:PURPOSE OF REVIEW:The effect of urate lowering treatment (ULT) on cardiovascular (CV) risk and mortality in gout has been a topic of interest. This review discusses the CV effect of ULT and comparative CV safety among ULT agents. RECENT FINDINGS:The mechanism linking gout with CV risk is not fully understood but seems...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-019-0843-8

    authors: Kang EH,Kim SC

    更新日期:2019-07-24 00:00:00

  • Takayasu Arteritis: Recent Developments.

    abstract:PURPOSE OF REVIEW:Takayasu arteritis (TA) is a granulomatous inflammatory disorder that affects large vessels, especially aorta and its proximal branches. Its diagnosis can be extremely challenging due to the non-specificity of the systemic inflammatory manifestations during the early phase of the disease and usually f...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-019-0848-3

    authors: Zaldivar Villon MLF,de la Rocha JAL,Espinoza LR

    更新日期:2019-07-18 00:00:00

  • Macrophages in Systemic Sclerosis: Novel Insights and Therapeutic Implications.

    abstract:PURPOSE OF REVIEW:Macrophages play key roles in tissue homeostasis and immune surveillance, mobilizing immune activation in response to microbial invasion and promoting wound healing to repair damaged tissue. However, failure to resolve macrophage activation can lead to chronic inflammation and fibrosis, and ultimately...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-019-0831-z

    authors: Toledo DM,Pioli PA

    更新日期:2019-05-23 00:00:00

  • The Primary Cilium: Emerging Role as a Key Player in Fibrosis.

    abstract:PURPOSE OF REVIEW:The myofibroblast is the culprit in the pathogenesis of fibrosis in systemic sclerosis (SSc). Activation of morphogen signaling pathways has been shown to be critically involved in organ fibrosis. Remarkably, the cellular receptors and key molecules from these signaling pathways are localized in the p...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-019-0822-0

    authors: Teves ME,Strauss JF 3rd,Sapao P,Shi B,Varga J

    更新日期:2019-05-21 00:00:00

  • Idiopathic Pericarditis-an Autoinflammatory Disease?

    abstract:PURPOSE OF THE REVIEW:Idiopathic acute and recurrent pericarditis are rare diseases of unknown origin. Here, we review trigger factors, pathomechanism, and treatment options for acute and recurrent pericarditis. RECENT FINDINGS:Acute pericarditis can be triggered by viral infections, myocardial ischemia, heart cathete...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-019-0820-2

    authors: Blank N,Lorenz HM

    更新日期:2019-03-09 00:00:00

  • Cell Senescence in Lupus.

    abstract:PURPOSE OF REVIEW:The concept of cellular senescence has been evolving. Although originally proposed based on studies of serum-driven replication of cell lines in vitro, it is now clear that cellular senescence occurs in vivo. It has also become clear that cellular senescence can be triggered by a number of stimuli suc...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-019-0800-6

    authors: Gao L,Slack M,Barnas JL,McDavid A,Anolik J,Looney RJ

    更新日期:2019-01-14 00:00:00

  • Anxiety and Mood Disorders in Systemic Lupus Erythematosus: Current Insights and Future Directions.

    abstract:PURPOSE OF REVIEW:Optimal management of anxiety and mood disorders in patients with systemic lupus erythematosus (SLE) is limited by an incomplete understanding of their pathophysiology and a lack of treatment guidelines. This review aims to critically synthesize recent literature on these conditions in adults with SLE...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-018-0797-2

    authors: Tisseverasinghe A,Peschken C,Hitchon C

    更新日期:2018-11-12 00:00:00

  • Cardiovascular and Metabolic Comorbidities in Rheumatoid Arthritis.

    abstract:PURPOSE OF THE REVIEW:An increased prevalence of cardiovascular risk factors in rheumatoid arthritis (RA) is reported. The absolute cardiovascular risk in RA patients is higher than in the general population, and although the RA prognosis has gradually improved, premature cardiovascular (CV) mortality remains a matter ...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-018-0790-9

    authors: Romano S,Salustri E,Ruscitti P,Carubbi F,Penco M,Giacomelli R

    更新日期:2018-11-05 00:00:00

  • Gender Differences in Axial Spondyloarthritis: Women Are Not So Lucky.

    abstract:PURPOSE OF REVIEW:Ankylosing spondylitis (AS) was historically seen as a predominantly male disease. However, more recent data showed a more homogenous sex prevalence. Unfortunately, in many studies in axial spondyloarthritis (axSpA), the number of women included is low and the analyses are often not stratified for gen...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-018-0744-2

    authors: Rusman T,van Vollenhoven RF,van der Horst-Bruinsma IE

    更新日期:2018-05-12 00:00:00

  • New Trials in Lupus and where Are we Going.

    abstract:PURPOSE OF REVIEW:To review progress in the field of clinical trials for SLE. RECENT FINDINGS:Treatment development for SLE has been marked by failures of many later phase studies, representing billions of dollars of lost research and development funding. Recently, more successful Phase II trials have tested reduction...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-018-0745-1

    authors: Thanou A,Merrill JT

    更新日期:2018-05-03 00:00:00

  • How Can We Improve Disease Education in People with Gout?

    abstract:PURPOSE OF REVIEW:Gout management is currently suboptimal despite excellent available therapy. Gout patient education has been shown to enhance medication adherence and self-management, but needs improvement. We explored the literature on gout patient education including gaps in gout patient knowledge; use of written m...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-018-0720-x

    authors: Fields TR,Batterman A

    更新日期:2018-03-08 00:00:00

  • Peripheral Mechanisms Contributing to Osteoarthritis Pain.

    abstract:PURPOSE OF REVIEW:Osteoarthritis (OA) is the most common form of arthritis and a major source of pain and disability worldwide. OA-associated pain is usually refractory to classically used analgesics, and disease-modifying therapies are still lacking. Therefore, a better understanding of mechanisms and mediators contri...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-018-0716-6

    authors: Syx D,Tran PB,Miller RE,Malfait AM

    更新日期:2018-02-26 00:00:00

  • Bariatric Surgery Prior to Total Joint Arthroplasty, Does it Decrease the Risk of Obesity Related Perioperative Complications?

    abstract:PURPOSE OF REVIEW:The purpose of this review paper is to provide an overview of the relationship between obesity, osteoarthritis, arthroplasty outcomes, and the potential use of bariatric surgery to improve these outcomes. RECENT FINDINGS:Unfortunately, the findings in the currently available literature evaluating the...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-018-0717-5

    authors: Stavrakis AI,Khoshbin A,McLawhorn AS,Parks ML

    更新日期:2018-02-21 00:00:00

  • Can positive affect attenuate (persistent) pain? State of the art and clinical implications.

    abstract:PURPOSE OF REVIEW:Pain is an intense experience that can place a heavy burden on peoples' lives. The identification of psychosocial risk factors led to the development of effective pain treatments. However, effect sizes are modest. Accumulating evidence suggests that enhancing protective factors might also impact on (w...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-017-0703-3

    authors: Hanssen MM,Peters ML,Boselie JJ,Meulders A

    更新日期:2017-11-09 00:00:00

  • Chikungunya Virus-Associated Disease.

    abstract:PURPOSE OF REVIEW:Chikungunya virus (CHIKV) infection has become increasingly prevalent in the last decade not only across the southern hemisphere but also, because of a recently documented viral mutation, in southern Europe and the USA. With the global spread of CHIKV infection, practitioners should know its epidemiol...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-017-0694-0

    authors: Hua C,Combe B

    更新日期:2017-10-05 00:00:00

  • Cannabis and Cannabinoids for Chronic Pain.

    abstract:PURPOSE OF REVIEW:The purpose of this study was to provide the most up-to-date scientific evidence of the potential analgesic effects, or lack thereof, of the marijuana plant (cannabis) or cannabinoids, and of safety or tolerability of their long-term use. RECENT FINDINGS:We found that inhaled (smoked or vaporized) ca...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-017-0693-1

    authors: Romero-Sandoval EA,Kolano AL,Alvarado-Vázquez PA

    更新日期:2017-10-05 00:00:00

  • Do Biologic Therapies for Rheumatoid Arthritis Offset Treatment-Related Resource Utilization and Cost? A Review of the Literature and an Instrumental Variable Analysis.

    abstract:PURPOSE OF REVIEW:One justification for using expensive biologic therapy in rheumatoid arthritis (RA) has been that it can reduce future healthcare utilization such as joint surgeries and physician visits. However, the evidence to support this assertion is unclear. We conducted a review of the literature for studies wh...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-017-0680-6

    authors: Bansback N,Fu E,Sun H,Guh D,Zhang W,Lacaille D,Milbers K,Anis AH

    更新日期:2017-09-01 00:00:00

  • Innate Immune Responses and Osteoarthritis.

    abstract:PURPOSE OF THE REVIEW:Osteoarthritis (OA) is a chronic, painful joint disease that affects approximately 40% of adults over 70 year. Age is the strongest predictor of OA, while obesity is considered the primary preventable risk factor for OA. Both conditions are associated with abnormal innate immune inflammatory respo...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-017-0672-6

    authors: Kalaitzoglou E,Griffin TM,Humphrey MB

    更新日期:2017-08-01 00:00:00

  • Lung Transplantation in Patients With Systemic Sclerosis.

    abstract:PURPOSE OF REVIEW:The purpose of this study was to highlight recent findings on evaluation for lung transplantation and outcomes after transplantation in patients with systemic sclerosis (scleroderma). RECENT FINDINGS:The recognition that extra-pulmonary disease manifestations can seriously compromise post-transplant ...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-017-0650-z

    authors: Shah RJ,Boin F

    更新日期:2017-05-01 00:00:00

  • The Paradox of Bone Formation and Bone Loss in Ankylosing Spondylitis: Evolving New Concepts of Bone Formation and Future Trends in Management.

    abstract:PURPOSE OF REVIEW:The purpose of the study is to briefly review the molecular mechanisms that leads to structural damage in ankylosing spondylitis (AS), defined as new bone formation resulting in complete or incomplete ankylosis of the spine, and the impact of treatment with biologics to retard this process. RECENT FI...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-017-0644-x

    authors: Magrey MN,Khan MA

    更新日期:2017-04-01 00:00:00

  • The Changing Face of Clinical Trials in Psoriatic Arthritis.

    abstract:PURPOSE OF THE REVIEW:We will address current treatment and unmet needs in psoriatic arthritis (PsA), examine existing randomized controlled trials (RCTs), and consider options for new trial designs and challenges in their implementation. RECENT FINDINGS:While therapeutic options for PsA have rapidly increased, there ...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-017-0642-z

    authors: Ogdie A,Coates L

    更新日期:2017-04-01 00:00:00

  • Regulatory T Cells in SLE: Biology and Use in Treatment.

    abstract::T regulatory cells (Tregs) represent a phenotypically and functionally heterogeneous group of lymphocytes that exert immunosuppressive activities on effector immune responses. Tregs play a key role in maintaining immune tolerance and homeostasis through diverse mechanisms which involve interactions with components of ...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-016-0616-6

    authors: Giang S,La Cava A

    更新日期:2016-11-01 00:00:00

  • AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION): 5-Year Update.

    abstract::Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) is the first-ever international network created to design and conduct large-scale, multicenter clinical trials and research in persistently antiphospholipid antibody (aPL)-positive patients. Since its inception in 2010, th...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-016-0611-y

    authors: Barbhaiya M,Andrade D,Erkan D,APS ACTION.

    更新日期:2016-10-01 00:00:00

  • Gout and Osteoarthritis: Associations, Pathophysiology, and Therapeutic Implications.

    abstract::Osteoarthritis (OA), the most common type of arthritis worldwide, is a degenerative disease of diarthrodial joints resulting in pain, reduced quality of life, and socioeconomic burden. Gout, the most common form of inflammatory arthritis, is a consequence of persistently elevated levels of urate and the formation of p...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-016-0613-9

    authors: Yokose C,Chen M,Berhanu A,Pillinger MH,Krasnokutsky S

    更新日期:2016-10-01 00:00:00

  • Current Perspectives on Arthroplasty in Systemic Lupus Erythematosus: Rates, Outcomes, and Adverse Events.

    abstract::Systemic lupus erythematosus (SLE) is a chronic debilitating condition with significant impact on the musculoskeletal system. Arthroplasty may be indicated for damage related to active lupus or its treatment. As therapies for SLE have advanced, morbidity and mortality have declined, while the rate of joint replacement...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-016-0608-6

    authors: Kasturi S,Goodman S

    更新日期:2016-09-01 00:00:00

  • Imaging in Spondyloarthritis: Controversies in Recognition of Early Disease.

    abstract::Advanced imaging has become essential for recognition of clinically suspected early spondyloarthritis. This report summarizes recent progress towards a data-driven comprehensive definition of a positive sacroiliac joint MRI in axial spondyloarthritis, which incorporates contextual information provided by structural le...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-016-0607-7

    authors: Weber U,Jurik AG,Lambert RG,Maksymowych WP

    更新日期:2016-09-01 00:00:00

  • Economic Theory and Self-Reported Measures of Presenteeism in Musculoskeletal Disease.

    abstract::This study had two objectives: to describe the historical development of self-reported presenteeism instruments that can be used to identify and measure presenteeism as a result of musculoskeletal disease (MSD) and to identify if, and how many of these, presenteeism instruments are underpinned by economic theory. Syst...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-016-0600-1

    authors: Jones C,Payne K,Gannon B,Verstappen S

    更新日期:2016-08-01 00:00:00

  • The Bench-to-Bedside Story of IL-17 and the Therapeutic Efficacy of its Targeting in Spondyloarthritis.

    abstract::TNF-blocking biologics have revolutionized the care of patients with spondyloarthritis, a group of clinically overlapping conditions that includes ankylosing spondylitis and psoriatic arthritis. However, incomplete response rates speak to the need for alternative therapeutic approaches. Over the last decade, animal mo...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-016-0585-9

    authors: Smith JA

    更新日期:2016-06-01 00:00:00

  • Rheumatoid Arthritis Pharmacotherapies: Do They Have Anti-Atherosclerotic Activity?

    abstract::Rheumatoid arthritis (RA) is associated with a heightened risk of cardiovascular disease (CVD) events, presumably related to a greater burden of atherosclerosis, as well as atherosclerotic plaques that tend to be inflamed and rupture prone. Many of the inflammatory pathways underlying the pathobiology of RA are also r...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-016-0578-8

    authors: Giles JT

    更新日期:2016-05-01 00:00:00

  • B Cell Therapies, Approved and Emerging: a Review of Infectious Risk and Prevention During Use.

    abstract::The development of B cell-targeted biologics represents a major advance in the treatment of autoimmune rheumatic diseases. As with other immunosuppressive agents, risk of infection is a key clinical concern. This review summarises safety data from 15 years of experience of rituximab in autoimmune diseases with a parti...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-015-0539-7

    authors: Md Yusof MY,Vital EM,Buch MH

    更新日期:2015-10-01 00:00:00

  • Lipid and Metabolic Changes in Rheumatoid Arthritis.

    abstract::While the most obvious manifestations of rheumatoid arthritis (RA) involve inflammation and damage in the synovial joints, the systemic effects of the condition are widespread and life-threatening. Of particular interest is the 'lipid paradox' of RA, where patients with a numerically equivocal starting lipid profile h...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-015-0534-z

    authors: McGrath CM,Young SP

    更新日期:2015-09-01 00:00:00

  • Novel Insights into Osteoarthritis Joint Pathology from Studies in Mice.

    abstract::Osteoarthritis causes tremendous individual suffering and staggering societal costs, but due to our limited understanding of the underlying molecular and cellular mechanisms, our avenues for treating this disease are very restricted. Recent years have seen a drastic increase in the use of genetically modified mice to ...

    journal_title:Current rheumatology reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11926-015-0524-1

    authors: Moon PM,Beier F

    更新日期:2015-08-01 00:00:00

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