听力与言语-语言病理学

行为科学

医学伦理学

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  • Associations Between Cognitive Function and Levels of Glutamatergic Metabolites and Gamma-Aminobutyric Acid in Antipsychotic-Naïve Patients With Schizophrenia or Psychosis.

    abstract:BACKGROUND:Abnormal glutamate and GABA (gamma-aminobutyric acid) levels have been found in the early phase of schizophrenia and may underlie cognitive deficits. However, the association between cognitive function and levels of glutamatergic metabolites and GABA has not been investigated in a large group of antipsychoti...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2020.06.027

    authors: Bojesen KB,Broberg BV,Fagerlund B,Jessen K,Thomas MB,Sigvard A,Tangmose K,Nielsen MØ,Andersen GS,Larsson HBW,Edden RAE,Rostrup E,Glenthøj BY

    更新日期:2021-02-01 00:00:00

  • Prepubertal Environmental Enrichment Prevents Dopamine Dysregulation and Hippocampal Hyperactivity in MAM Schizophrenia Model Rats.

    abstract:BACKGROUND:Schizophrenia (SCZ) is a neurodevelopmental disorder with a progressive, prolonged course. Early prevention for SCZ is promising but overall lacks support from preclinical evidence. Previous studies have tested environmental enrichment (EE) in certain models of SCZ and discovered a broadly beneficial effect ...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2020.09.023

    authors: Zhu X,Grace AA

    更新日期:2021-02-01 00:00:00

  • Neural Correlates Associated With Suicide and Nonsuicidal Self-injury in Youth.

    abstract::There is no definitive neural marker of suicidal thoughts and behaviors (STBs) or nonsuicidal self-injury (NSSI), and relative to adults, research in youth is more limited. This comprehensive review focuses on magnetic resonance imaging studies reporting structural and functional neural correlates of STBs and NSSI in ...

    journal_title:Biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/j.biopsych.2020.06.002

    authors: Auerbach RP,Pagliaccio D,Allison GO,Alqueza KL,Alonso MF

    更新日期:2021-01-15 00:00:00

  • Neural Correlates of Emotion Regulation in Adolescents and Emerging Adults: A Meta-analytic Study.

    abstract:BACKGROUND:The development of adaptive implicit and explicit emotion regulation skills is crucial for mental health. Adolescence and emerging adulthood are periods of heightened risk for psychopathology associated with emotion dysregulation, and neurodevelopmental mechanisms have been proposed to account for this incre...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2020.08.006

    authors: Pozzi E,Vijayakumar N,Rakesh D,Whittle S

    更新日期:2021-01-15 00:00:00

  • Neuroimaging-based Individualized Prediction of Cognition and Behavior for Mental Disorders and Health: Methods and Promises.

    abstract::The neuroimaging community has witnessed a paradigm shift in biomarker discovery from using traditional univariate brain mapping approaches to multivariate predictive models, allowing the field to move toward a translational neuroscience era. Regression-based multivariate models (hereafter "predictive modeling") provi...

    journal_title:Biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/j.biopsych.2020.02.016

    authors: Sui J,Jiang R,Bustillo J,Calhoun V

    更新日期:2020-12-01 00:00:00

  • Imaging Cortical Dopamine Transmission in Cocaine Dependence: A [11C]FLB 457-Amphetamine Positron Emission Tomography Study.

    abstract:BACKGROUND:Positron emission tomography studies have demonstrated less dopamine D2/3 receptor availability and blunted psychostimulant-induced dopamine release in cocaine-dependent subjects (CDSs). No studies in CDSs have reported the in vivo status of D2/3 and dopamine release in the cortex. Basic and functional imagi...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2020.04.001

    authors: Narendran R,Mason NS,Himes ML,Frankle WG

    更新日期:2020-11-15 00:00:00

  • Cord Serum Cytokines at Birth and Children's Anxiety-Depression Trajectories From 3 to 8 Years: The EDEN Mother-Child Cohort.

    abstract:BACKGROUND:Recent research suggests that immune dysregulation in pregnancy could be a risk factor for anxiety and depression symptoms in offspring. Whereas animal studies have demonstrated the importance of the link between perinatal cytokines and abnormal behaviors in offspring, human epidemiological studies in this a...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2020.10.009

    authors: Galera C,Barbosa S,Collet O,Khalfallah O,Aouizerate B,Sutter-Dalley AL,Koehl M,Capuron L,Van der Waerden J,Melchior M,Côté S,Heude B,Glaichenhaus N,Davidovic L,EDEN Mother–Child Cohort Study Group.

    更新日期:2020-10-24 00:00:00

  • Neonatal Levels of Acute Phase Proteins and Risk of Autism Spectrum Disorder.

    abstract:BACKGROUND:Immune signaling pathways influence neurodevelopment and are hypothesized to contribute to the etiology of autism spectrum disorder (ASD). We aimed to assess risk of ASD in relation to levels of neonatal acute phase proteins (APPs), key components of innate immune function, measured in neonatal dried blood s...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2020.09.005

    authors: Gardner RM,Lee BK,Brynge M,Sjöqvist H,Dalman C,Karlsson H

    更新日期:2020-09-10 00:00:00

  • Markers of Psychosis Risk in the General Population.

    abstract::The categorical approach to defining schizophrenia spectrum disorders requires meeting established criteria. To advance early identification and intervention in young people, the field has progressed to studying help-seeking individuals who are at clinical high risk based on subthreshold psychosis spectrum symptoms, a...

    journal_title:Biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/j.biopsych.2020.02.002

    authors: Taylor JH,Calkins ME,Gur RE

    更新日期:2020-08-15 00:00:00

  • Aberrant Salience, Information Processing, and Dopaminergic Signaling in People at Clinical High Risk for Psychosis.

    abstract::The aberrant salience hypothesis proposes that striatal dopamine dysregulation causes misattribution of salience to irrelevant stimuli leading to psychosis. Recently, new lines of preclinical evidence on information coding by subcortical dopamine coupled with computational models of the brain's ability to predict and ...

    journal_title:Biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/j.biopsych.2020.03.012

    authors: Howes OD,Hird EJ,Adams RA,Corlett PR,McGuire P

    更新日期:2020-08-15 00:00:00

  • Attention Alterations in Pediatric Anxiety: Evidence From Behavior and Neuroimaging.

    abstract:BACKGROUND:Pediatric anxiety disorders involve greater capture of attention by threatening stimuli. However, it is not known if disturbances extend to nonthreatening stimuli, as part of a pervasive disturbance in attention-related brain systems. We hypothesized that pediatric anxiety involves greater capture of attenti...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2020.07.016

    authors: Perino MT,Yu Q,Myers MJ,Harper JC,Baumel WT,Petersen SE,Barch DM,Luby JL,Sylvester CM

    更新日期:2020-08-01 00:00:00

  • Reciprocal Copy Number Variations at 22q11.2 Produce Distinct and Convergent Neurobehavioral Impairments Relevant for Schizophrenia and Autism Spectrum Disorder.

    abstract:BACKGROUND:22q11.2 deletions and duplications are copy number variations (CNVs) that predispose to developmental neuropsychiatric disorders. Both CNVs are associated with autism spectrum disorder (ASD), while the deletion confers disproportionate risk for schizophrenia. Neurobehavioral profiles associated with these re...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.12.028

    authors: Lin A,Vajdi A,Kushan-Wells L,Helleman G,Hansen LP,Jonas RK,Jalbrzikowski M,Kingsbury L,Raznahan A,Bearden CE

    更新日期:2020-08-01 00:00:00

  • Vulnerable and Resilient Phenotypes in a Mouse Model of Anorexia Nervosa.

    abstract:BACKGROUND:Increased physical activity is a common feature of anorexia nervosa (AN). Although high activity levels are associated with greater risk of developing AN, particularly when combined with dieting, most individuals who diet and exercise maintain a healthy body weight. It is unclear why some individuals develop...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2020.06.030

    authors: Beeler JA,Mourra D,Zanca RM,Kalmbach A,Gellman C,Klein BY,Ravenelle R,Serrano P,Moore H,Rayport S,Mingote S,Burghardt NS

    更新日期:2020-07-16 00:00:00

  • Approaches to Defining Common and Dissociable Neurobiological Deficits Associated With Psychopathology in Youth.

    abstract::Psychiatric disorders show high rates of comorbidity and nonspecificity of presenting clinical symptoms, while demonstrating substantial heterogeneity within diagnostic categories. Notably, many of these psychiatric disorders first manifest in youth. We review progress and next steps in efforts to parse heterogeneity ...

    journal_title:Biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/j.biopsych.2019.12.015

    authors: Kaczkurkin AN,Moore TM,Sotiras A,Xia CH,Shinohara RT,Satterthwaite TD

    更新日期:2020-07-01 00:00:00

  • De Novo Damaging DNA Coding Mutations Are Associated With Obsessive-Compulsive Disorder and Overlap With Tourette's Disorder and Autism.

    abstract:BACKGROUND:Obsessive-compulsive disorder (OCD) is a debilitating neuropsychiatric disorder with a genetic risk component, yet identification of high-confidence risk genes has been challenging. In recent years, risk gene discovery in other complex psychiatric disorders has been achieved by studying rare de novo (DN) cod...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.09.029

    authors: Cappi C,Oliphant ME,Péter Z,Zai G,Conceição do Rosário M,Sullivan CAW,Gupta AR,Hoffman EJ,Virdee M,Olfson E,Abdallah SB,Willsey AJ,Shavitt RG,Miguel EC,Kennedy JL,Richter MA,Fernandez TV

    更新日期:2020-06-15 00:00:00

  • Estimating the Heritability of Developmental Change in Neural Connectivity, and Its Association With Changing Symptoms of Attention-Deficit/Hyperactivity Disorder.

    abstract:BACKGROUND:Twin studies show that age-related change in symptoms of attention-deficit/hyperactivity disorder (ADHD) is heritable. However, we do not know the heritability of the development of the neural substrates underlying the disorder. Here, we estimated the heritability of developmental change in white matter trac...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2020.06.007

    authors: Sudre G,Bouyssi-Kobar M,Norman L,Sharp W,Choudhury S,Shaw P

    更新日期:2020-06-13 00:00:00

  • Characterization of Single Gene Copy Number Variants in Schizophrenia.

    abstract:BACKGROUND:Genetic studies of schizophrenia have implicated numerous risk loci including several copy number variants (CNVs) of large effect and hundreds of loci of small effect. In only a few cases has a specific gene been clearly identified. Rare CNVs affecting a single gene offer a potential avenue to discovering sc...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.09.023

    authors: Szatkiewicz JP,Fromer M,Nonneman RJ,Ancalade N,Johnson JS,Stahl EA,Rees E,Bergen SE,Hultman CM,Kirov G,O'Donovan M,Owen M,Holmans P,Sklar P,Sullivan PF,Purcell SM,Crowley JJ,Ruderfer DM

    更新日期:2020-04-15 00:00:00

  • A Pattern of Cognitive Deficits Stratified for Genetic and Environmental Risk Reliably Classifies Patients With Schizophrenia From Healthy Control Subjects.

    abstract:BACKGROUND:Schizophrenia risk is associated with both genetic and environmental risk factors. Furthermore, cognitive abnormalities are established core characteristics of schizophrenia. We aim to assess whether a classification approach encompassing risk factors, cognition, and their associations can discriminate patie...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.11.007

    authors: Antonucci LA,Pergola G,Pigoni A,Dwyer D,Kambeitz-Ilankovic L,Penzel N,Romano R,Gelao B,Torretta S,Rampino A,Trojano M,Caforio G,Falkai P,Blasi G,Koutsouleris N,Bertolino A

    更新日期:2020-04-15 00:00:00

  • Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease.

    abstract:BACKGROUND:Major prevention trials for Alzheimer's disease (AD) are now focusing on multidomain lifestyle interventions. However, the exact combination of behavioral factors related to AD pathology remains unclear. In 2 cohorts of cognitively unimpaired individuals at risk of AD, we examined which combinations of perso...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2020.01.023

    authors: Pichet Binette A,Vachon-Presseau É,Morris J,Bateman R,Benzinger T,Collins DL,Poirier J,Breitner JCS,Villeneuve S,Dominantly Inherited Alzheimer Network (DIAN).,PREVENT-AD Research Group.

    更新日期:2020-02-06 00:00:00

  • Brain Development in School-Age and Adolescent Girls: Effects of Turner Syndrome, Estrogen Therapy, and Genomic Imprinting.

    abstract:BACKGROUND:The study of Turner syndrome (TS) offers a unique window of opportunity for advancing scientific knowledge of how X chromosome gene imprinting, epigenetic factors, hormonal milieu, and chronologic age affect brain development in females. METHODS:We described brain growth trajectories in 55 girls with TS and...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.07.032

    authors: O'Donoghue S,Green T,Ross JL,Hallmayer J,Lin X,Jo B,Huffman LC,Hong DS,Reiss AL

    更新日期:2020-01-15 00:00:00

  • Polygenic Risk Scores for Developmental Disorders, Neuromotor Functioning During Infancy, and Autistic Traits in Childhood.

    abstract:BACKGROUND:Impaired neuromotor development is often one of the earliest observations in children with autism spectrum disorder (ASD). We investigated whether a genetic predisposition to developmental disorders was associated with nonoptimal neuromotor development during infancy and examined the genetic correlation betw...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.06.006

    authors: Serdarevic F,Tiemeier H,Jansen PR,Alemany S,Xerxa Y,Neumann A,Robinson E,Hillegers MHJ,Verhulst FC,Ghassabian A

    更新日期:2020-01-15 00:00:00

  • Molecular Basis of Opioid Action: From Structures to New Leads.

    abstract::Since the isolation of morphine from the opium poppy over 200 years ago, the molecular basis of opioid action has remained the subject of intense inquiry. The identification of specific receptors responsible for opioid function and the discovery of many chemically diverse molecules with unique opioid-like efficacies h...

    journal_title:Biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/j.biopsych.2019.08.028

    authors: Manglik A

    更新日期:2020-01-01 00:00:00

  • Fighting Females: Neural and Behavioral Consequences of Social Defeat Stress in Female Mice.

    abstract:BACKGROUND:Despite the twofold higher prevalence of major depressive and posttraumatic stress disorders in women compared with men, most clinical and preclinical studies have focused on male subjects. We used an ethological murine model to study several cardinal symptoms of affective disorders in the female targets of ...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.05.005

    authors: Newman EL,Covington HE 3rd,Suh J,Bicakci MB,Ressler KJ,DeBold JF,Miczek KA

    更新日期:2019-11-01 00:00:00

  • Which Dopamine Polymorphisms Are Functional? Systematic Review and Meta-analysis of COMT, DAT, DBH, DDC, DRD1-5, MAOA, MAOB, TH, VMAT1, and VMAT2.

    abstract:BACKGROUND:Many polymorphisms in dopamine genes are reported to affect cognitive, imaging, or clinical phenotypes. It is often inferred or assumed that such associations are causal, mediated by a direct effect of the polymorphism on the gene product itself. However, the supporting evidence is not always clear. METHODS...

    journal_title:Biological psychiatry

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.biopsych.2019.05.014

    authors: Tunbridge EM,Narajos M,Harrison CH,Beresford C,Cipriani A,Harrison PJ

    更新日期:2019-10-15 00:00:00

  • The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology of Schizophrenia: A Review of the Evidence.

    abstract::Schizophrenia is a debilitating mental illness that affects approximately 1% of the world's population. Despite much research in its neurobiology to aid in developing new treatments, little progress has been made. One system that has not received adequate attention is the kappa opioid system and its potential role in ...

    journal_title:Biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/j.biopsych.2019.05.012

    authors: Clark SD,Abi-Dargham A

    更新日期:2019-10-01 00:00:00

  • Multiscale Neuroscience of Psychiatric Disorders.

    abstract::The human brain comprises a multiscale network with multiple levels of organization. Neurons with dendritic and axonal connections form the microscale fabric of brain circuitry, and macroscale brain regions and white matter connections form the infrastructure for system-level brain communication and information integr...

    journal_title:Biological psychiatry

    pub_type: 杂志文章,评审

    doi:10.1016/j.biopsych.2019.05.015

    authors: van den Heuvel MP,Scholtens LH,Kahn RS

    更新日期:2019-10-01 00:00:00

  • Domain-Specific Cognitive Impairments in Humans and Flies With Reduced CYFIP1 Dosage.

    abstract:BACKGROUND:Deletions encompassing a four-gene region on chromosome 15 (BP1-BP2 at 15q11.2), seen at a population frequency of 1 in 500, are associated with increased risk for schizophrenia, epilepsy, and other common neurodevelopmental disorders. However, little is known in terms of how these common deletions impact co...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.04.008

    authors: Woo YJ,Kanellopoulos AK,Hemati P,Kirschen J,Nebel RA,Wang T,Bagni C,Abrahams BS

    更新日期:2019-08-15 00:00:00

  • The Functional Brain Organization of an Individual Allows Prediction of Measures of Social Abilities Transdiagnostically in Autism and Attention-Deficit/Hyperactivity Disorder.

    abstract:BACKGROUND:Autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD) are associated with complex changes as revealed by functional magnetic resonance imaging. To date, neuroimaging-based models are not able to characterize individuals with sufficient sensitivity and specificity. Further, although evi...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.02.019

    authors: Lake EMR,Finn ES,Noble SM,Vanderwal T,Shen X,Rosenberg MD,Spann MN,Chun MM,Scheinost D,Constable RT

    更新日期:2019-08-15 00:00:00

  • Central Histamine Boosts Perirhinal Cortex Activity and Restores Forgotten Object Memories.

    abstract:BACKGROUND:A method that promotes the retrieval of lost long-term memories has not been well established. Histamine in the central nervous system is implicated in learning and memory, and treatment with antihistamines impairs learning and memory. Because histamine H3 receptor inverse agonists upregulate histamine relea...

    journal_title:Biological psychiatry

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.biopsych.2018.11.009

    authors: Nomura H,Mizuta H,Norimoto H,Masuda F,Miura Y,Kubo A,Kojima H,Ashizuka A,Matsukawa N,Baraki Z,Hitora-Imamura N,Nakayama D,Ishikawa T,Okada M,Orita K,Saito R,Yamauchi N,Sano Y,Kusuhara H,Minami M,Takahashi H,Ikeg

    更新日期:2019-08-01 00:00:00

  • A-Kinase Anchoring Protein 150 and Protein Kinase A Complex in the Basolateral Amygdala Contributes to Depressive-like Behaviors Induced by Chronic Restraint Stress.

    abstract:BACKGROUND:The basolateral amygdala (BLA) has been widely implicated in the pathophysiology of major depressive disorder. A-kinase anchoring protein 150 (AKAP150) directs kinases and phosphatases to synaptic glutamate receptors, controlling synaptic transmission and plasticity. However, the role of the AKAP150 in the B...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.03.967

    authors: Zhou HY,He JG,Hu ZL,Xue SG,Xu JF,Cui QQ,Gao SQ,Zhou B,Wu PF,Long LH,Wang F,Chen JG

    更新日期:2019-07-15 00:00:00

  • Advanced Paternal Age and Early Onset of Schizophrenia in Sporadic Cases: Not Confounded by Parental Polygenic Risk for Schizophrenia.

    abstract:BACKGROUND:Whether paternal age effect on schizophrenia is a causation or just an association due to confounding by selection into late parenthood is still debated. We investigated the association between paternal age and early onset of schizophrenia in offspring, controlling for both paternal and maternal predispositi...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.01.023

    authors: Wang SH,Hsiao PC,Yeh LL,Liu CM,Liu CC,Hwang TJ,Hsieh MH,Chien YL,Lin YT,Huang YT,Chen CY,Chandler SD,Faraone SV,Neale B,Glatt SJ,Tsuang MT,Hwu HG,Chen WJ

    更新日期:2019-07-01 00:00:00

  • Resting-State Functional Connectivity and Psychotic-like Experiences in Childhood: Results From the Adolescent Brain Cognitive Development Study.

    abstract:BACKGROUND:Psychotic-like experiences (PLEs) during childhood are associated with greater risk of developing a psychotic disorder (and other mental disorders), highlighting the importance of identifying neural correlates of childhood PLEs. Three major cortical networks-the cingulo-opercular network (CON), default mode ...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.01.013

    authors: Karcher NR,O'Brien KJ,Kandala S,Barch DM

    更新日期:2019-07-01 00:00:00

  • Stimulation of Peroxisome Proliferator-Activated Receptor-α by N-Palmitoylethanolamine Engages Allopregnanolone Biosynthesis to Modulate Emotional Behavior.

    abstract:BACKGROUND:The endocannabinoid and neurosteroid systems regulate emotions and stress responses. Activation of peroxisome proliferator-activated receptor (PPAR)-α by the endocannabinoid congener N-palmitoylethanolamine (PEA) regulates pathophysiological systems (e.g., inflammation, oxidative stress) and induces peripher...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.02.006

    authors: Locci A,Pinna G

    更新日期:2019-06-15 00:00:00

  • Fear Extinction Retention: Is It What We Think It Is?

    abstract::There has been an explosion of research on fear extinction in humans in the past 2 decades. This has not only generated major insights, but also brought a new goal into focus: how to maintain extinction memory over time (i.e., extinction retention). We argue that there are still important conceptual and procedural cha...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.02.011

    authors: Lonsdorf TB,Merz CJ,Fullana MA

    更新日期:2019-06-15 00:00:00

  • Neural Correlates of Failed Inhibitory Control as an Early Marker of Disordered Eating in Adolescents.

    abstract:BACKGROUND:Binge eating and other forms of disordered eating behavior (DEB) are associated with failed inhibitory control. This study investigated the neural correlates of failed inhibitory control as a potential biomarker for DEB. METHODS:The study used prospective longitudinal data from the European IMAGEN study ado...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.01.027

    authors: Bartholdy S,O'Daly OG,Campbell IC,Banaschewski T,Barker G,Bokde ALW,Bromberg U,Büchel C,Quinlan EB,Desrivières S,Flor H,Frouin V,Garavan H,Gowland P,Heinz A,Ittermann B,Martinot JL,Paillère Martinot ML,Nees F,Orfano

    更新日期:2019-06-01 00:00:00

  • De Novo Protein Synthesis Mediated by the Eukaryotic Elongation Factor 2 Is Required for the Anxiolytic Effect of Oxytocin.

    abstract:BACKGROUND:The neuropeptide oxytocin (OXT) mediates its actions, including anxiolysis, via its G protein-coupled OXT receptor. Within the paraventricular nucleus of the hypothalamus (PVN), OXT-induced anxiolysis is mediated, at least in part, via activation of the mitogen-activated protein kinase pathway following calc...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2019.01.010

    authors: Martinetz S,Meinung CP,Jurek B,von Schack D,van den Burg EH,Slattery DA,Neumann ID

    更新日期:2019-05-15 00:00:00

  • Infections, Anti-infective Agents, and Risk of Deliberate Self-harm and Suicide in a Young Cohort: A Nationwide Study.

    abstract:BACKGROUND:Evidence links infections to mental disorders and suicidal behavior. However, knowledge is sparse regarding less severe infections, anti-infective treatment, and deliberate self-harm. Using nationwide Danish longitudinal registers, we estimated associations between infections treated with anti-infective agen...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2018.11.008

    authors: Gjervig Hansen H,Köhler-Forsberg O,Petersen L,Nordentoft M,Postolache TT,Erlangsen A,Benros ME

    更新日期:2019-05-01 00:00:00

  • The Role of Dendritic Brain-Derived Neurotrophic Factor Transcripts on Altered Inhibitory Circuitry in Depression.

    abstract:BACKGROUND:A parallel downregulation of brain-derived neurotrophic factor (BDNF) and somatostatin (SST), a marker of inhibitory gamma-aminobutyric acid interneurons that target pyramidal cell dendrites, has been reported in several brain areas of subjects with major depressive disorder (MDD). Rodent genetic studies sug...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2018.09.026

    authors: Oh H,Piantadosi SC,Rocco BR,Lewis DA,Watkins SC,Sibille E

    更新日期:2019-03-15 00:00:00

  • Probing Brain Developmental Patterns of Myelination and Associations With Psychopathology in Youths Using Gray/White Matter Contrast.

    abstract:BACKGROUND:Cerebral myeloarchitecture shows substantial development across childhood and adolescence, and aberrations in these trajectories are relevant for a range of mental disorders. Differential myelination between intracortical and subjacent white matter can be approximated using signal intensities in T1-weighted ...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2018.09.027

    authors: Norbom LB,Doan NT,Alnæs D,Kaufmann T,Moberget T,Rokicki J,Andreassen OA,Westlye LT,Tamnes CK

    更新日期:2019-03-01 00:00:00

  • Cortical Paired Associative Stimulation Influences Response Inhibition: Cortico-cortical and Cortico-subcortical Networks.

    abstract:BACKGROUND:The ability to stop a suboptimal response is integral to decision making and is commonly impaired across psychiatric disorders. Cortical paired associative stimulation (cPAS) is a form of transcranial magnetic stimulation in which paired pulses can induce plasticity at cortical synapses. Here we used cPAS pr...

    journal_title:Biological psychiatry

    pub_type: 杂志文章

    doi:10.1016/j.biopsych.2018.03.009

    authors: Kohl S,Hannah R,Rocchi L,Nord CL,Rothwell J,Voon V

    更新日期:2019-02-15 00:00:00

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