听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览INTERNATIONAL REVIEWS OF IMMUNOLOGY期刊下所有文献
  • Endothelial dysfunction sustains immune response in atherosclerosis: potential cause for ineffectiveness of prevailing drugs.

    abstract::Vascular endothelial dysfunction (ED) forms the cornerstone in the development of atherosclerotic lesions that clinically manifest as ischemia, myocardial infarction, stroke or peripheral arterial disease. ED can be triggered by various risk factors including hypercholesterolemia, hypertension, hyperhomocystenemia and...

    journal_title:International reviews of immunology

    pub_type: 杂志文章

    doi:10.1080/08830185.2020.1866568

    authors: Akhtar S,Sharma A

    更新日期:2021-01-13 00:00:00

  • HLA-G expression in melanomas.

    abstract:OBJECTIVE:Human leukocyte antigen G (HLA-G) is a non-classical HLA class I molecule involved in inducing tolerance at the feto-maternal interface and in escape of immune response by tumor cells. The aim of the study is to review the published literature on the expression of HLA-G in malignant melanomas and its clinicop...

    journal_title:International reviews of immunology

    pub_type: 杂志文章

    doi:10.1080/08830185.2020.1869732

    authors: Marletta S,Girolami I,Munari E,Pantanowitz L,Bernasconi R,Torresani E,Brunelli M,Eccher A

    更新日期:2021-01-11 00:00:00

  • ABO-Incompatible Liver Transplantation - A Review of the Historical Background and Results.

    abstract::ABO-incompatible liver transplantation (ABOi LT) using conventional immunosuppression has been considered a contraindication due to the high risk for antibody-mediated complications potentially resulting in graft loss. However, organ shortage has led to the development of anti-A/B antibody reducing immunosuppressive p...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.1080/08830185.2019.1601720

    authors: Dahlgren US,Bennet W

    更新日期:2019-01-01 00:00:00

  • Emerging roles of noncoding RNAs in T cell differentiation and functions in autoimmune diseases.

    abstract::Noncoding RNA comprises of microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) that are abundantly present in mammalian transcriptome. These noncoding RNAs have been implicated in multiple biological processes through the regulation of gene expression. Each of these noncoding RNAs were found to have multiple genes ta...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.1080/08830185.2019.1648454

    authors: Roy S,Awasthi A

    更新日期:2019-01-01 00:00:00

  • Chicken toll-like receptors and their significance in immune response and disease resistance.

    abstract::Infectious diseases are a major challenge for the poultry industry that causes widespread production losses. Thus, management and control of poultry health and diseases are essential for the viability of the industry. Toll-like receptors are best characterized as membrane-bound receptors that perform a central role in...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.1080/08830185.2019.1659258

    authors: Nawab A,An L,Wu J,Li G,Liu W,Zhao Y,Wu Q,Xiao M

    更新日期:2019-01-01 00:00:00

  • Calcium Signaling Commands Phagosome Maturation Process.

    abstract::Phagosome-lysosome (P-L) fusion is one of the central immune-effector responses of host. It is known that phagosome maturation process is associated with numerous signaling cascades and among these, important role of calcium (Ca2+) signaling has been realized recently. Ca2+ plays key roles in actin rearrangement, acti...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.1080/08830185.2019.1592169

    authors: Pradhan G,Raj Abraham P,Shrivastava R,Mukhopadhyay S

    更新日期:2019-01-01 00:00:00

  • Regulatory T-cell dynamics with abatacept treatment in rheumatoid arthritis.

    abstract::The progressive damage in rheumatoid arthritis (RA) has been linked to an increase in inflammatory Th1/Th17 cells and a decrease in number or function of immunomodulatory regulatory T cells (Tregs). Many therapies that are effective in RA are shown to affect Th1/Th17 cells and/or Tregs. One such therapy, abatacept, ut...

    journal_title:International reviews of immunology

    pub_type: 杂志文章

    doi:10.1080/08830185.2018.1465943

    authors: Langdon K,Haleagrahara N

    更新日期:2018-01-01 00:00:00

  • The mechanisms of IL-17A on promoting tumor metastasis.

    abstract::In recent decades, extensive studies have indicated that IL-17A plays an important role in tumor progression and metastasis, but the underlying mechanisms are not immediately clear. In this review, we examined the literature from the recent years concerning the study of IL-17A in four kinds of tumor transfer paths, in...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.1080/08830185.2017.1356296

    authors: Xu LL,Li ZJ,Niu XL,Deng WM

    更新日期:2017-11-02 00:00:00

  • Targeting BAFF and APRIL in systemic lupus erythematosus and other antibody-associated diseases.

    abstract::The B cell-stimulating molecules, BAFF (B cell activating factor) and APRIL (a proliferation-inducing ligand), are critical factors in the maintenance of the B cell pool and humoral immunity. In addition, BAFF and APRIL are involved in the pathogenesis of a number of human autoimmune diseases, with elevated levels of ...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.1080/08830185.2016.1276903

    authors: Samy E,Wax S,Huard B,Hess H,Schneider P

    更新日期:2017-01-02 00:00:00

  • Divergence of Vascular Specification in Visceral Lymphoid Organs-Genetic Determinants and Differentiation Checkpoints.

    abstract::Despite their functional similarities, peripheral lymphoid tissues are remarkably different according to their developmental properties and structural characteristics, including their specified vasculature. Access of leukocytes to these organs critically depends on their interactions with the local endothelium, where ...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2015.1059427

    authors: Kellermayer Z,Hayasaka H,Kajtár B,Simon D,Robles EF,Martinez-Climent JA,Balogh P

    更新日期:2016-11-01 00:00:00

  • Distinct Strategies Employed by Dendritic Cells and Macrophages in Restricting Mycobacterium tuberculosis Infection: Different Philosophies but Same Desire.

    abstract::Dendritic cells (DCs) and macrophages (Mϕs) are professional antigen-presenting cells (APCs) that can efficiently phagocytose Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis (TB). It is quite interesting to mention here that DCs and Mϕs use distinct strategies to combat and eliminate Mtb. Simil...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2015.1015718

    authors: Khan N,Vidyarthi A,Pahari S,Agrewala JN

    更新日期:2016-09-02 00:00:00

  • Innate Lymphoid Cells: A Promising New Regulator in Fibrotic Diseases.

    abstract::Fibrosis is a consequence of chronic inflammation and the persistent accumulation of extracellular matrix, for which the cycle of tissue injury and repair becomes a predominant feature. Both the innate and adaptive immune systems play key roles in the progress of fibrosis. The recently identified subsets of innate lym...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2015.1068304

    authors: Zhang Y,Tang J,Tian Z,van Velkinburgh JC,Song J,Wu Y,Ni B

    更新日期:2016-09-02 00:00:00

  • Neurotensin, a Novel Messenger to Cross-Link Inflammation and Tumor Invasion via Epithelial-Mesenchymal Transition Pathway.

    abstract::Multiple cytokines and growth factors are critical for the prognosis of cancer which has been regarded as a worldwide health problem. Recently, neuropeptides, soluble factors regulating a series of functions in the central nervous system, have also been demonstrated to stimulate the proliferation and migration of tumo...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2014.952412

    authors: Ye Y,Liu P,Wang Y,Li H,Wei F,Cheng Y,Han L,Yu J

    更新日期:2016-07-03 00:00:00

  • Dendritic Cells in the Context of Human Tumors: Biology and Experimental Tools.

    abstract::Dendritic cells (DC) are the most potent and versatile antigen-presenting cells (APC) in the immune system. DC have an exceptional ability to comprehend the immune context of a captured antigen based on molecular signals identified from its vicinity. The analyzed information is then conveyed to other immune effector c...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2015.1096935

    authors: Volovitz I,Melzer S,Amar S,Bocsi J,Bloch M,Efroni S,Ram Z,Tárnok A

    更新日期:2016-01-01 00:00:00

  • Emerging view of autophagy in systemic lupus erythematosus.

    abstract::Aberrations of both innate immunity and adaptive immunity in genetically predisposed individuals evoked by environmental factors are suggested to be implicated in pathophysiological processes of systemic lupus erythematosus (SLE). Autophagy, a degradation pathway in which cytoplasmic content is engulfed and degraded b...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2013.879711

    authors: Zhou XJ,Cheng FJ,Zhang H

    更新日期:2015-05-01 00:00:00

  • Editorial: in this issue.

    abstract::In this issue, we are hosting several reviews on topics of broad interests, such as therapeutic or prophylactic antibodies, and the role of autophagy in autoimmunity. ...

    journal_title:International reviews of immunology

    pub_type: 社论

    doi:10.3109/08830185.2015.1041855

    authors: Bot A

    更新日期:2015-05-01 00:00:00

  • Chimeric antigen receptor engineering: a right step in the evolution of adoptive cellular immunotherapy.

    abstract::Cancer immunotherapy comprises different therapeutic strategies that exploit the use of distinct components of the immune system, with the common goal of specifically targeting and eradicating neoplastic cells. These varied approaches include the use of specific monoclonal antibodies, checkpoint inhibitors, cytokines,...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2015.1018419

    authors: Figueroa JA,Reidy A,Mirandola L,Trotter K,Suvorava N,Figueroa A,Konala V,Aulakh A,Littlefield L,Grizzi F,Rahman RL,Jenkins MR,Musgrove B,Radhi S,D'Cunha N,D'Cunha LN,Hermonat PL,Cobos E,Chiriva-Internati M

    更新日期:2015-03-01 00:00:00

  • Cellular metabolism on T-cell development and function.

    abstract::Cell metabolism is closely related to the host immunity in many respects. We herein briefly summarized the recent progress on the roles of cellular metabolism in T-cell development, homeostasis, differentiation and functions. Relatively quiescent naïve T cells only require energy for survival and migration, and they m...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2014.902452

    authors: Chen H,Yang T,Zhu L,Zhao Y

    更新日期:2015-01-01 00:00:00

  • Metabolic mysteries of the inflammatory response: T cell polarization and plasticity.

    abstract::While simultaneously maintaining homeostasis and reducing further harm to the host, the immune system is equipped to eliminate both tumors and pathogenic microorganisms. Bifurcated into cell-mediated and humoral immunity, the adaptive immune system requires a series of complex and coordinated signals to drive the prol...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2014.974748

    authors: Fracchia KM,Walsh CM

    更新日期:2015-01-01 00:00:00

  • TLR cross-talk confers specificity to innate immunity.

    abstract::Cross-talk within the innate immune pathways is highly complex and contains many unknowns. Here, we discuss the different combinations of PAMPs, together with the sequence, order, and dosage of consecutive PAMP challenges, which determine the nature of the immune response by macrophages. The engagement of different To...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2014.921164

    authors: Tan RS,Ho B,Leung BP,Ding JL

    更新日期:2014-11-01 00:00:00

  • Erythrocyte and leukocyte: two partners in bacteria killing.

    abstract::Leukocytes can't perform phagocytosis in blood stream. Blood velocity prevents phagocytosis because there is no time for leukocyte to recognize and catch bacteria. Bloodstream clearance from pathogens is performed by erythrocytes. During motion in bloodstream erythrocytes become charged by triboelectric effect. This c...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2014.956359

    authors: Minasyan HA

    更新日期:2014-11-01 00:00:00

  • Transcriptomic network support distinct roles of classical and non-classical monocytes in human.

    abstract::Classical and non-classical monocytes are two well-defined subsets of monocytes displaying distinct roles. They differentially express numerous genes relevant to their primary role. Using five independent transcriptomic microarray datasets, we ruled out several inconsistent genes and identified common genes consistent...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2014.902453

    authors: Anbazhagan K,Duroux-Richard I,Jorgensen C,Apparailly F

    更新日期:2014-11-01 00:00:00

  • The role of human papilloma virus (HPV) infection in non-anogenital cancer and the promise of immunotherapy: a review.

    abstract::Over the past 30 years, human papilloma virus (HPV) has been shown to play a role in the development of various cancers. Most notably, HPV has been linked to malignant progression in neoplasms of the anogenital region. However, high-risk HPV has also been suggested to play a significant role in the development of canc...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2014.911857

    authors: Cobos C,Figueroa JA,Mirandola L,Colombo M,Summers G,Figueroa A,Aulakh A,Konala V,Verma R,Riaz J,Wade R,Saadeh C,Rahman RL,Pandey A,Radhi S,Nguyen DD,Jenkins M,Chiriva-Internati M,Cobos E

    更新日期:2014-10-01 00:00:00

  • Pathogen infection as a possible cause for autoimmune hepatitis.

    abstract::Autoimmune disorders afflicting the liver comprise the bona fide autoimmune diseases, primary biliary cirrhosis, primary sclerosing cholangitis, and autoimmune hepatitis as well as drug-induced autoimmune-like diseases, such as halothane hepatitis. Whereas drug-induced forms of acute or chronic hepatitis often have a ...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2014.921162

    authors: Christen U,Hintermann E

    更新日期:2014-07-01 00:00:00

  • Current status of allograft tolerance in intestinal transplantation.

    abstract::Solid organ transplantation has become a clinical practice after the development of different immunosuppressive drugs that allowed controlling rejection. The price to be paid for that is the permanent risk of infections and malignancies and a significant drug-associated toxicity. The establishment of transplant tolera...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2013.829468

    authors: Meier D,Rumbo M,Gondolesi GE

    更新日期:2014-05-01 00:00:00

  • DC-SIGN, DC-SIGNR and LSECtin: C-type lectins for infection.

    abstract::The C-type lectins DC-SIGN, DC-SIGNR and LSECtin are encoded by the lectin gene cluster on chromosome 19p13.3 and perform cell-adhesion and pathogen recognition functions on dendritic cells, liver cells and lymph node sinusoidal endothelial cells. DC-SIGN and DC-SIGNR share similar overall gene and protein molecule st...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2013.834897

    authors: Zhang F,Ren S,Zuo Y

    更新日期:2014-01-01 00:00:00

  • Molecular mechanisms and cell targets of Th17 cells in the gastrointestinal tract: an innate sense of adaptivity.

    abstract::T-helper (TH) 17 activation is crucial for protective immune responses against bacteria and fungi at mucosal surfaces, but it can also be implicated in the pathogenesis of several autoimmune and chronic inflammatory diseases, such as inflammatory bowel diseases (IBD). Although rapid progress was made elucidating induc...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2013.829471

    authors: Verdier J,Ruemmele FM

    更新日期:2013-10-01 00:00:00

  • How far are we from understanding the genetic basis of Hashimoto's thyroiditis?

    abstract::Hashimoto's thyroiditis (HT), an autoimmune thyroid disease (AITD), is becoming more and more prevalent in the recent years. Data on family and twin studies carry evidence for strong genetic influence on AITD susceptibility and development. The most common approaches to unravel the background of those diseases are who...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2012.755175

    authors: Jabrocka-Hybel A,Skalniak A,Piątkowski J,Pach D,Hubalewska-Dydejczyk A

    更新日期:2013-06-01 00:00:00

  • Epstein-Barr virus (EBV) microRNAs: involvement in cancer pathogenesis and immunopathology.

    abstract::The Epstein-Barr virus (EBV), which infects over 90% of adults, appears to have evolved to exploit the normal biology of B-cell development in order to persist as a life-long asymptomatic infection. However, EBV can contribute to oncogenesis. It has become evident that alterations in the expression of microRNAs (miRNA...

    journal_title:International reviews of immunology

    pub_type: 杂志文章

    doi:10.3109/08830185.2012.748053

    authors: Lopes LF,Ruiz Miyazawa KW,de Almeida ER,Serafim KG,de Almeida Gualtieri K,Costa IC,Felipe I,Pavanelli WR,Watanabe MA

    更新日期:2013-06-01 00:00:00

  • Uveitis in mouse and man.

    abstract::Uveitis is underappreciated as a sight-threatening cause of blindness. There are two broad causative classes of uveitis: infectious and non-infectious. Non-infectious uveitis is considered a prototypical autoimmune disorder based mainly on data from experimental models in the mouse. Several different experimental mode...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2012.747524

    authors: Forrester JV,Klaska IP,Yu T,Kuffova L

    更新日期:2013-02-01 00:00:00

  • The use of agonistic anti-CD40 therapy in treatments for cancer.

    abstract::Agonistic anti-CD40 antibody is a potent stimulator of anti-tumor immune responses due to its action on both immune and tumor cells. It has the ability to "precondition" dendritic cells, allowing them to prime effective cytotoxic T-cell responses. Thus, anti-CD40 antibody provides an ideal therapy for combination with...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2012.698338

    authors: Khong A,Nelson DJ,Nowak AK,Lake RA,Robinson BW

    更新日期:2012-08-01 00:00:00

  • The interplay between diet and emerging allergy: what can we learn from Indigenous Australians?

    abstract::The pathophysiology of atopic diseases, including asthma and allergy, is the result of complex gene-environment interactions. Since European colonization the Indigenous population of Australia has undergone significant changes with respect to their lifestyle as hunter-gatherers. These changes have had a detrimental ef...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2012.667180

    authors: Walton SF,Weir C

    更新日期:2012-06-01 00:00:00

  • In this issue: Tec kinases in the crosshairs.

    abstract::Tec family kinases are the second largest family of non-receptor tyrosine kinases, of critical importance to the biology of cells derived from the bone marrow. Significant progress in this area during the last decade revealed a role for several of these kinases in inflammatory and oncologic disorders. This led to the ...

    journal_title:International reviews of immunology

    pub_type: 社论

    doi:10.3109/08830185.2012.671692

    authors: Faris M,Bot A

    更新日期:2012-04-01 00:00:00

  • Chimeric antigen receptors in cancer immuno-gene therapy: current status and future directions.

    abstract::The concept of chimeric antigen receptors (CARs) as molecules able to redirect T lymphocytes toward tumor cells is currently being exploited in the field of cancer immunotherapy. Despite promising preliminary results, some clinical trials evidenced limitations for this technology that must be overcome for more extensi...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2011.595855

    authors: Chicaybam L,Sodré AL,Bonamino M

    更新日期:2011-10-01 00:00:00

  • Sperm protein 17: clinical relevance of a cancer/testis antigen, from contraception to cancer immunotherapy, and beyond.

    abstract::Sperm protein 17 belongs to the cancer/testis antigen family and was found to play a key role in the cell fusion process between the mammalian spermatozoa and egg. Sperm protein 17-specific autoantibodies in vasectomized males suggest its high expression in the testis. Sperm protein 17 expression levels are low or abs...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2011.569903

    authors: Chiriva-Internati M

    更新日期:2011-04-01 00:00:00

  • Role of CD4+ cytotoxic T lymphocytes in the control of viral diseases and cancer.

    abstract::Our knowledge on the physiological role of CD4(+) T lymphocytes has improved in the last decade: available data convincingly demonstrate that, besides the 'helper' activity, CD4(+) T cells may be also endowed with lytic properties. The cytotoxic function of these effector cells has a relevant role in the control of pa...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830185.2010.489658

    authors: Martorelli D,Muraro E,Merlo A,Turrini R,Rosato A,Dolcetti R

    更新日期:2010-08-01 00:00:00

  • Dendritic cells in systemic lupus erythematosus.

    abstract::Systemic lupus erythematosus (SLE) persists as a chronic inflammatory autoimmune disease and is characterized by the production of autoantibodies and immune complexes that affect multiple organs. The underlying mechanism that triggers and sustains disease are complex and involve certain susceptibility genes and enviro...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830181003602507

    authors: Seitz HM,Matsushima GK

    更新日期:2010-04-01 00:00:00

  • Membrane and soluble ILT3 are critical to the generation of T suppressor cells and induction of immunological tolerance.

    abstract::The tolerogenic phenotype of human dendritic cells is characterized by high cell surface expression of the inhibitory receptor ILT3. ILT3 signals both intracellularly inhibiting tyrosine phosphorylation, NF-kappaB and MAPK p38 activity, transcription of certain co-stimulatory molecules, secretion of cytokines and chem...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830180903281185

    authors: Vlad G,Chang CC,Colovai AI,Vasilescu ER,Cortesini R,Suciu-Foca N

    更新日期:2010-04-01 00:00:00

  • Development of dendritic cell-based immunotherapy for autoimmunity.

    abstract::Dendritic cells are professional antigen-presenting cells that maintain immune tolerance to self-antigens by deleting or controlling the pathogenicity of auto-reactive T-cells. Dendritic cell-based immunotherapies show great promise for the restoration of tolerance in autoimmune disease. Dendritic cells can be modifie...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830180903281193

    authors: Hilkens CM,Isaacs JD,Thomson AW

    更新日期:2010-04-01 00:00:00

  • Mechanisms and efficacy of immunobiologic therapies for inflammatory bowel diseases.

    abstract::Current advances in understanding of the pathogenesis of inflammatory bowel disease have encouraged the development of many new therapies targeted at specific and non-specific mediators of the inflammatory bowel disease inflammatory pathway. Crohn's disease and ulcerative colitis, two common inflammatory bowel disease...

    journal_title:International reviews of immunology

    pub_type: 杂志文章,评审

    doi:10.3109/08830180903437212

    authors: Ghosh N,Chaki R,Mandal V,Lin GD,Mandal SC

    更新日期:2010-01-01 00:00:00

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