abstract：:The H9N2 influenza virus has been frequently endemic in poultry, infected mammals and humans and has threatened public health. It is therefore imperative to understand the molecular mechanism enabling this virus to jump from avian to mammalian species. In this study, two H9N2 influenza viruses were isolated from the s...

journal_title：Acta virologica

authors： Ren W,Zhang CH,Li G,Liu G,Shan H,Li J

更新日期：2020-01-01 00:00:00

abstract：:Tick-borne encephalitis (TBE), a disease caused by tick-borne encephalitis virus (TBEV), represents a serious neural infection of humans in Europe and Asia. The main reservoir hosts of TBEV are ticks, rodents and insectivores, but domestic animals may also be infected with the virus. This review summarizes what is kno...

journal_title：Acta virologica

authors： Salat J,Ruzek D

更新日期：2020-01-01 00:00:00

abstract：:The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has undoubtedly created an emerging disease of topmost public health priority spilling  throughout the globe. The diagnosis currently relies on a multiplex of criteria including the epidemiology, clinical manifestations and in vitro diagnostics. Pr...

journal_title：Acta virologica

authors： Priyanka,Choudhary OP,Singh I

更新日期：2020-01-01 00:00:00

abstract：:Every year, the poultry industry experiences significant economic losses due to epidemics of Newcastle disease virus (NDV). Developing new vaccines by identifying and using the immunogenic hemagglutinin-neuraminidase (HN) protein can protect the poultry industry. In the present study, the full-length HN protein was ex...

journal_title：Acta virologica

authors： Shahid N,Rao AQ,Ahad A,Gul A,Latif A,Azam S,Shahid M,Akhtar S,Shahid AA,Husnain T

更新日期：2020-01-01 00:00:00

abstract：:The present paper describes first full genome sequence of the Garlic virus D (GarV-D) from northern India with a genome size of 8425 bp long ssRNA. The infected leaves and bulbs of garlic variety Yamuna Safed (G-282) plants suspected for GarV-D infection were collected with the aim to identify contagion virus during M...

journal_title：Acta virologica

authors： Singh J,Truong TN,An D,Prajapati MR,Manav A,Quoc NB,A KR,Kumar P,Kumar R,Baranwal VK

更新日期：2020-01-01 00:00:00

abstract：:Avian infectious bronchitis virus (IBV) and avian pathogenic Escherichia coli (APEC) are two important respiratory pathogens in the chicken. The co-infection can lead to chronic complications and considerable economic losses in the poultry industry worldwide. In the present study, we compared differential transcriptio...

journal_title：Acta virologica

authors： Hashemi S,Ghalyanchilangeroudi A,Hosseini SM,Sheikhi N

更新日期：2020-01-01 00:00:00

abstract：:Whitefly-transmitted viruses of the genus Begomovirus (the family Geminiviridae) have become a limiting factor for agricultural productivity in many warmer parts of the world. The economies of Pakistan and India have, since the early 1990s, suffered losses due to cotton leaf curl disease (CLCuD). The disease is caused...

journal_title：Acta virologica

authors： Ali I,Khurshid M,Iqbal Z,Shafiq M,Amin I,Mansoor S,Briddon RW

更新日期：2019-01-01 00:00:00

abstract：:Recently, mitochondria have been shown to have a vital role in the innate immune response to viral infection. In response, viruses such as adenovirus, have developed mechanisms to alter mitochondrial function through direct or indirect interaction with the mitochondria. The interaction of human recombinant adenoviral ...

journal_title：Acta virologica

authors： Morrison BJ,Abu-Asab M,Morris JC,Steel JC

更新日期：2019-01-01 00:00:00

abstract：:The genome sequence of a novel species of the genus Waikavirus (the family Secoviridae), which we named Brassica napus RNA virus 1 (BnRV1), was identified in a rapeseed (Brassica napus) transcriptome dataset. The BnRV1 genome was 12,293 nucleotides long followed by a poly(A) tail. Two open reading frames (ORFs), calle...

journal_title：Acta virologica

authors： Park D,Hahn Y

更新日期：2019-01-01 00:00:00

abstract：:The human immunodeficiency virus (HIV) envelope, via a key extracellular amino acid sequence, may simulate the functionality of native undecapeptide substance P (SP) acting through the host's neurokinin 1 (SP preferring) receptor (NK-1R). Human monocytes and macrophages express both NK-1Rs and SP. In HIV/AIDS the NK-1...

journal_title：Acta virologica

authors： Muñoz M,Coveñas R,Kramer M

更新日期：2019-01-01 00:00:00

abstract：:Acute gastroenteritis (AGE) is one of the most frequently occuring illnesses in children and adults worldwide. In February 2017, two AGE outbreaks occurred in two adjacent schools in Huzhou city, Zhenjiang province of China. We detected high percentages of recombinant norovirus GII.P16/GII.2 in one school and chicken ...

journal_title：Acta virologica

authors： Li Y,Zhang P,Wu X,Wen D,Ji L,Chen L,Liu G,Fu X,Zhang J,Zhang C,Han J

更新日期：2019-01-01 00:00:00

abstract：:Betaflexiviridae is a family of plant-infecting RNA viruses with 11 recognized genera, of which genomes have diverse organization with three to six open reading frames (ORFs). A genome sequence of a novel Betaflexiviridae species, named Salvia divinorum RNA virus 1 (SdRV1), was identified in Salvia divinorum, herbal m...

journal_title：Acta virologica

authors： Goh CJ,Hahn Y

更新日期：2019-01-01 00:00:00

abstract：:39K protein was proven to be the most notable hyperphosphorylated protein of Bombyx mori nucleopolyhedrovirus (BmNPV), since its amino acid 136 has the highest phosphorylation ratio (16.683) among all of BmNPV phosphorylated proteins (Shobahah et al., 2017). Therefore, we inserted positive (mimicking phosphorylation) ...

journal_title：Acta virologica

authors： Yan H,Shobahah J,Wei M,Obeng E,Xue S,Hu D,Quan Y,Yu W

更新日期：2019-01-01 00:00:00

abstract：:The blood-nerve barrier (BNB) shields peripheral nerves from the blood in order to maintain the homeostasis of the nervous system. In the field of infectious diseases, little information is currently available concerning the BNB. Recently documented evidence in virology suggests that elevated permeability of the BNB b...

journal_title：Acta virologica

authors： Mori I

更新日期：2018-01-01 00:00:00

abstract：:With only a single class of antiviral drugs existing for treatment of influenza (neuraminidase inhibitors), the search for novel effective compounds is urgently needed. We evaluated a low molecular mass compound, enisamium iodide (FAV00A), against influenza virus infections in primary differentiated normal human bronc...

journal_title：Acta virologica

authors： Cocking D,Cinatl J,Boltz DA,Peng X,Johnson W,Muzzio M,Syarkevych O,Kostyuk G,Goy A,Mueller L,Margitich VI

更新日期：2018-01-01 00:00:00

abstract：:The samples from eggplants showing mixed symptoms of little leaf and mosaic were collected from two districts (Mirzapur and Varanasi) of Uttar Pradesh, India. The total nucleic acid extracted from these samples was amplified by PCR using universal 16S rRNA primers specific to phytoplasma and primers specific to DNA-A-...

journal_title：Acta virologica

authors： Venkataravanappa V,Prasanna HC,Lakshminarayana CN,Reddy MK

更新日期：2018-01-01 00:00:00

abstract：:Homologous interference in vitro is defined as the ability of primary viral infection to prevent secondary homologous superinfection. Non-cytopathic bovine viral diarrhea virus (ncp BVDV) has been classified according to the exaltation of Newcastle disease phenomenon (END) as END positive (E+) and END negative (E-) st...

journal_title：Acta virologica

authors： Muhsen M,Lee P

更新日期：2018-01-01 00:00:00

abstract：:Hypothiocyanite (OSCN-) is a natural component of human saliva and is produced by the lactoperoxidase (LPO)/thiocyanate/hydrogen peroxide (H2O2) system. OSCN- has been previously shown to exhibit antiviral activity against influenza viruses (IFV) A/H1N1/2009 and A/H1N2/2009 in vitro as well as antimicrobial and antifu...

journal_title：Acta virologica

authors： Sugita C,Shin K,Wakabayashi H,Tsuhako R,Yoshida H,Watanabe W,Kurokawa M

更新日期：2018-01-01 00:00:00

abstract：:Alzheimer's disease (AD) the most common form of dementia is characterized by cognitive decline and progressive loss of neurons in the central nervous system. Despite huge scientific progress, there are only few animal models that recapitulate at least majority of the AD pathology and related symptomatology. Therefore...

journal_title：Acta virologica

authors： Cubinková V,Valachová B,Brezováková V,Szabó R,Zimová I,Kostecká Z,Jadhav S

更新日期：2017-01-01 00:00:00

abstract：:Group A rotavirus is the leading cause of acute gastroenteritis in cattle and swine. Although, vaccination against this virus is an effective strategy for prevention, additional strategy to control disease is necessary. Egg yolk immunoglobulin (IgY)-based passive immunization could be a better option in preventing thi...

journal_title：Acta virologica

authors： Kim HS,Lee B,Han SY,Jung YT

更新日期：2017-01-01 00:00:00

abstract：:Gamma irradiation is a non-thermal processing technique used to disinfect harmful microorganisms in agriculture. This technology has been shown to be an effective method to control bacterial and fungal plant pathogens. However, its effect on viral plant pathogen is less understood. Gamma irradiation was evaluated for ...

journal_title：Acta virologica

authors： Jeong RD,Choi HS

更新日期：2017-01-01 00:00:00

abstract：:Neopterin and soluble CD14 (sCD14) are detected at high levels in hepatitis C virus (HCV) infections. We aimed to evaluate the role of these plasma immune activation biomarkers, for the indirect assessment of immune activation status of patients with low anti-HCV reactivity and a HCV infection. Low anti-HCV reactivity...

journal_title：Acta virologica

authors： Habip Z,Sohrabi P,Saribas S,Caliskan R,Demirci M,Karakullukcu A,Atalik K,Yuksel P,Uysal O,Kosan E,Bahar Tokman H,Kocazeybek B

更新日期：2017-01-01 00:00:00

abstract：:no abstract Keywords: no keywords. ...

journal_title：Acta virologica

authors： Škultéty Ľ

更新日期：2017-01-01 00:00:00

abstract：:Hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) plays a crucial role in induction of immune response against Newcastle disease infection. Mutation in residues 347 and 362 of HN linear antigenic site has been identified to be responsible for antigenic variations. Hence we studied antigenic dif...

journal_title：Acta virologica

authors： Mayahi V,Esmaelizad M

更新日期：2017-01-01 00:00:00

abstract：:In September 2011, the leaf samples of hosta cultivar 'Sum and substance' were collected from the collection of Gryshko' National Botanical Garden in Kyiv. The leaves showed dark green streaking and puckering along the leaf veins. Transmission electron microscopy revealed the presence of filamentous viral particles 13...

journal_title：Acta virologica

authors： Shchetynina A,Budzanivska I,Pereboychuk O,Sõmera M,Truve E

更新日期：2017-01-01 00:00:00

abstract：:Cauliflower mosaic virus (CaMV) - a plant pararetrovirus that naturally causes diseases in Brassicaceae and Solanaceae plant hosts worldwide - has been detected by PCR for the first time in herbarium samples of Usnea sp. lichens. The virus's presence in these lichens did not result in any micro- or macromorphological ...

journal_title：Acta virologica

authors： Petrzik K,Koloniuk I,Sarkisová T,Číhal L

更新日期：2016-06-01 00:00:00

abstract：UNLABELLED:As a paramyxovirus, Newcastle disease virus (NDV) has the ability to edit its P (phosphoprotein) gene to synthesize three kinds of viral protein (P, V and W). It is technically very difficult to differentiate P, V and W mRNAs, and little was known about NDV regulation of RNA-editing frequency. To investigate...

journal_title：Acta virologica

authors： Qiu X,Fu Q,Meng C,Yu S,Zhan Y,Dong L,Ren T,Sun Y,Tan L,Song C,Han X,Ding C

更新日期：2016-03-01 00:00:00

abstract：:Obesity is a metabolic disease characterized by low-level chronic inflammation. Obese individuals are susceptible to infection by viruses, and vaccination against these pathogens is less effective than in nonobese individuals. Here, we sought to explore the immunological environment in a mouse model of obesity induced...

journal_title：Acta virologica

authors： Cho WJ,Lee DK,Lee SY,Sohn SH,Park HL,Park YW,Kim H,Nam JH

更新日期：2016-01-01 00:00:00

abstract：:The effect of Ribavirin treatment for the chemotherapy of several grapevine viruses was evaluated. Four grapevine cultivars were repeatedly treated with Ribavirin in two different concentrations and with three different lengths of treatment. Repeating the Ribavirin treatment always had a significant effect on the numb...

journal_title：Acta virologica

authors： Komínek P,Komínková M,Jandová B

更新日期：2016-01-01 00:00:00

abstract：:The interferon system represents one of the components of the first line defence against influenza virus infection. Interferon omega (IFN-ω) is antigenetically different from IFN-α and IFN-β and can affect patients who are resistant to these IFNs. To improve the biological characterization of IFN-ω, we compared its ac...

journal_title：Acta virologica

authors： Škorvanová L,Švančarová P,Svetlíková D,Betáková T

更新日期：2015-12-01 00:00:00

abstract：:Porcine epidemic diarrhea (PED) caused by virulent strains of porcine epidemic diarrhea virus (PEDV) is a highly contagious enteric disease of swine characterized by severe enteritis, vomiting, and watery diarrhea. This study investigates the subcellular localization and function of PEDV M protein through examination ...

journal_title：Acta virologica

authors： Xu XG,Zhang HL,Zhang Q,Dong J,Huang Y,Tong DW

更新日期：2015-09-01 00:00:00

abstract：:Five H5N2 avian influenza viruses (AIVs) were isolated in Xianghai National Nature Reserve, Jilin Province, China in October 2011. They were all identified as low pathogenic AIVs (LPAIVs) based on their deduced amino acid sequences at the cleavage site of HA protein. Phylogenetic analysis revealed that all gene segmen...

journal_title：Acta virologica

authors： Yang S,Chen G,Sun J,Li F,Hua HC

更新日期：2015-06-01 00:00:00

abstract：:Homologs of Bombyx mori nuclear polyhedrosis virus (BmNPV) Bm67 gene ORF67 have been found in the genome of all lepidopteran nuclear polyhedrosis viruses, but their function is still not very clear. In order to analyze it we employed a  bacmid harboring the complete BmNPV genome including the Bm67 gene and expressing ...

journal_title：Acta virologica

authors： Shi Y,Zhang C,Xie C,Quan Y,Nie Z,Chen J,Lv Z,Zhang Y,Yu W

更新日期：2015-03-01 00:00:00

abstract：:The baculovirus-insect cell expression system (BES), one of the most popular systems for expression of eukaryotic proteins, was known to have drawbacks such as laborious manipulation of large-size baculovirus bacmids and the transfection procedure. These problems could be eliminated by direct infection of eukaryotic c...

journal_title：Acta virologica

authors： Yu X,Hua J,Hu G,Zhang J,Ma L

更新日期：2014-01-01 00:00:00

abstract：:Phages are excellent models for studying the mechanism of DNA replication in prokaryotes. Identification of phage proteins involved in phage DNA replication is the first prerequisite for elucidation of the phage replication module. We focused on replication proteins gp41 (a putative helicase from SF2 superfamily), gp4...

journal_title：Acta virologica

authors： Bukovská G,Halgašová N,Hromadová L,Koščová H,Bukovský M

更新日期：2014-01-01 00:00:00

abstract：:Overweight and obesity is becoming widespread enough to generate an acceptable and misleading social status. By 2030, in the USA up to 86 % of adults will be overweight or obese. Some selected statistical data based on the body mass index (BMI) indicated that overweight was not associated with increased mortality, thi...

journal_title：Acta virologica

authors： Lim JY,Oh E,Kim Y,Jung WW,Kim HS,Lee J,Sul D

更新日期：2014-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection, with an estimated 170 million carriers worldwide, remains a major cause of chronic liver disease. Current anti-HCV treatments have significant side effects and have met with only partial success. Therefore, a more effective therapeutic modality for HCV infection is needed. The stabil...

journal_title：Acta virologica

authors： Motavaf M,Safari S,Alavian SM

更新日期：2014-01-01 00:00:00

abstract：:Herpes simplex virus 1 (HSV-1) is one of the most prevalent human pathogens in both industrialized and developing countries. This study was performed to analyze the antiviral activity of purified flavonoid from Polygonum perfoliatum L. against HSV-1 infection in vitro and in vivo. Flavonoid showed no inhibitory effect...

journal_title：Acta virologica

authors： Zhang QG,Wei F,Liu Q,Chen LJ,Liu YY,Luo F,Xiong HR,Yang ZQ

更新日期：2014-01-01 00:00:00

abstract：:In this study, a major part of genome of the pestivirus isolate 297 from Slovakia, comprising the 7195 nt-long 5΄-UTR-NS3 region was sequenced and analyzed. Conserved cleavage sites between individual viral proteins of this region were determined and the number of amino acids of respective proteins was estimated as fo...

journal_title：Acta virologica

authors： Lešková V,Jacková A,Vlasáková M,Vilček S

更新日期：2013-01-01 00:00:00

abstract：:Tick-borne viruses are causative agents of several important human diseases. Tick-borne encephalitis virus (TBEV) is the most prominent representative considered medically to be the most important arbovirus (arthropod-borne virus) in Europe and northern Asia. Tick-borne virus transmission cycles are determined by the ...

journal_title：Acta virologica

authors： Havlíková S,Ličková M,Klempa B

更新日期：2013-01-01 00:00:00