听力与言语-语言病理学

行为科学

医学伦理学

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  • Hypertensive Disorders of Pregnancy and Cognitive Impairment: A Prospective Cohort Study.

    abstract:OBJECTIVE:To determine the association between hypertensive disorders of pregnancy (HDP) and cognitive impairment 15 years after pregnancy, we measured cognitive performance in 115 women with a history of HDP and in 481 women with a previous normotensive pregnancy. METHODS:This was a nested cohort study embedded in a ...

    journal_title:Neurology

    pub_type: 评论,杂志文章

    doi:10.1212/WNL.0000000000011363

    authors: Adank MC,Hussainali RF,Oosterveer LC,Ikram MA,Steegers EAP,Miller EC,Schalekamp-Timmermans S

    更新日期:2021-02-02 00:00:00

  • Defining the Lowest Threshold for Amyloid-PET to Predict Future Cognitive Decline and Amyloid Accumulation.

    abstract:INTRODUCTION:As clinical trials move toward earlier intervention, we sought to redefine the β-amyloid (Aβ)-PET threshold based on the lowest point in a baseline distribution that robustly predicts future Aβ accumulation and cognitive decline in 3 independent samples of clinically normal individuals. METHODS:Sequential...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011214

    authors: Farrell ME,Jiang S,Schultz AP,Properzi MJ,Price JC,Becker JA,Jacobs HIL,Hanseeuw BJ,Rentz DM,Villemagne VL,Papp KV,Mormino EC,Betensky RA,Johnson KA,Sperling RA,Buckley RF,Alzheimer's Disease Neuroimaging Initiative and t

    更新日期:2021-01-26 00:00:00

  • Microbleeds, Cerebral Hemorrhage, and Functional Outcome after Endovascular Thrombectomy.

    abstract:OBJECTIVE:-To determine whether pre-treatment cerebral microbleeds (CMBs) presence and burden are correlated with an increased risk of intracranial hemorrhage (ICH) or poor functional outcome following endovascular thrombectomy (EVT) for acute ischemic stroke (AIS). METHODS:-Consecutive patients treated by EVT for ant...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011566

    authors: Derraz I,Cagnazzo F,Gaillard N,Morganti R,Dargazanli C,Ahmed R,Pierre-Henri L,Riquelme C,Mourand I,Gascou G,Bonafe A,Arquizan C,Costalat V

    更新日期:2021-01-25 00:00:00

  • Efficacy of High-Intensity Aerobic Exercise on Brain MRI Measures in Multiple Sclerosis.

    abstract:OBJECTIVE:To determine whether 24 weeks of high-intensity progressive aerobic exercise (PAE) affects brain MRI measures in people with multiple sclerosis (MS). METHODS:We conducted a randomized, controlled, phase 2 trial (with a crossover follow-up) including an exercise group (supervised PAE followed by self-guided p...

    journal_title:Neurology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1212/WNL.0000000000011241

    authors: Langeskov-Christensen M,Grøndahl Hvid L,Nygaard MKE,Ringgaard S,Jensen HB,Nielsen HH,Petersen T,Stenager E,Eskildsen SF,Dalgas U

    更新日期:2021-01-12 00:00:00

  • Validation of the Alzheimer Disease Dementia Conversion-Related Pattern as an ATN Biomarker of Neurodegeneration.

    abstract:OBJECTIVE:To determine whether the Alzheimer's disease dementia conversion-related pattern (ADCRP) on [18F]FDG PET can serve as a valid predictor for the development of Alzheimer's disease dementia, the individual expression of the ADCRP (subject score) and its prognostic value were examined in subjects with mild cogni...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011521

    authors: Blazhenets G,Frings L,Ma Y,Sörensen A,Eidelberg D,Wiltfang J,Meyer PT,Alzheimer’s Disease Neuroimaging Initiative.

    更新日期:2021-01-06 00:00:00

  • Accuracy of Calculated Free Valproate Levels in Adult Patients With Status Epilepticus.

    abstract:OBJECTIVE:To test the accuracy of an equation in adult patients with status epilepticus that calculates the free concentration of serum valproic acid (fVPA) from the total concentration of serum valproic acid (tVPA) and serum albumin. METHODS:All adult patients with status epilepticus who were treated at a Swiss acade...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011000

    authors: Fisch U,Baumann SM,Semmlack S,Marsch S,Rüegg S,Sutter R

    更新日期:2021-01-05 00:00:00

  • Topographic Distribution of Amyloid-β, Tau, and Atrophy in Patients With Behavioral/Dysexecutive Alzheimer Disease.

    abstract:OBJECTIVE:To determine the associations between amyloid-PET, tau-PET, and atrophy with the behavioral/dysexecutive presentation of Alzheimer disease (AD), how these differ from amnestic AD, and how they correlate to clinical symptoms. METHODS:We assessed 15 patients with behavioral/dysexecutive AD recruited from a ter...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011081

    authors: Therriault J,Pascoal TA,Savard M,Benedet AL,Chamoun M,Tissot C,Lussier F,Kang MS,Thomas E,Terada T,Rej S,Massarweh G,Nasreddine Z,Vitali P,Soucy JP,Saha-Chaudhuri P,Gauthier S,Rosa-Neto P

    更新日期:2021-01-05 00:00:00

  • Association of Time of Day When Endovascular Therapy for Stroke Starts and Functional Outcome.

    abstract:OBJECTIVE:To investigate the association between EVT start time in acute ischemic stroke (AIS) and mid-term functional outcome. METHODS:This retrospective cohort study included all AIS cases treated with EVT from two stroke center registries from January 2012 to December 2018. The primary outcome was the score on the ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011449

    authors: Hajdu SD,Kaesmacher J,Michel PP,Sirimarco G,Knebel JF,Bartolini B,Kurmann CC,Puccinelli F,Mosimann PJ,Bonvin C,Arnold PM,Niederhäuser J,Eskandari A,Mordasini P,Gralla PJ,Fischer PU,Saliou PG

    更新日期:2021-01-04 00:00:00

  • Comparison of Phenotypic Characteristics and Prognosis Between Black and White Patients in a Tertiary ALS Clinic.

    abstract:OBJECTIVE:To compare characteristics between Black and White patients with amyotrophic lateral sclerosis (ALS) in order to identify disparities and phenotypic variability. METHODS:We performed database review for patients seen between 1997 and 2020 at the Emory ALS Center in Atlanta, Georgia. Patients with ALS were in...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011396

    authors: Brand D,Polak M,Glass JD,Fournier CN

    更新日期:2020-12-28 00:00:00

  • Epilepsy after brain infection in adults: A register-based population-wide study.

    abstract:OBJECTIVE:To describe risk and risk factors of epilepsy after hospitalization for brain infection in adults in Sweden. METHODS:This was a matched retrospective cohort study based on the comprehensive National Patient and Cause of Death Registers. All individuals age >18 without prior epilepsy who received inpatient ca...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010954

    authors: Zelano J,Westman G

    更新日期:2020-12-15 00:00:00

  • Thrombectomy vs medical management in low NIHSS acute anterior circulation stroke.

    abstract:OBJECTIVE:To undertake an effectiveness and safety analysis of EVT in patients with LVO and NIH Stroke Scale (NIHSS) score ≤6 using datasets of multicenter and multinational nature. METHODS:We pooled patients with anterior circulation occlusion from 3 prospective international cohorts. Patients were eligible if presen...

    journal_title:Neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1212/WNL.0000000000010955

    authors: Volny O,Zerna C,Tomek A,Bar M,Rocek M,Padr R,Cihlar F,Nevsimalova M,Jurak L,Havlicek R,Kovar M,Sevcik P,Rohan V,Fiksa J,Cernik D,Jura R,Vaclavik D,Cimflova P,Puig J,Dowlatshahi D,Khaw AV,Fainardi E,Najm M,De

    更新日期:2020-12-15 00:00:00

  • Basal ganglia dysmorphism in patients with Aicardi syndrome.

    abstract:OBJECTIVE:Aiming to detect associations between neuroradiologic and EEG evaluations and long-term clinical outcome in order to detect possible prognostic factors, a detailed clinical and neuroimaging characterization of 67 cases of Aicardi syndrome (AIC), collected through a multicenter collaboration, was performed. M...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011237

    authors: Masnada S,Pichiecchio A,Formica M,Arrigoni F,Borrelli P,Accorsi P,Bonanni P,Borgatti R,Bernardina BD,Danieli A,Darra F,Deconinck N,De Giorgis V,Dulac O,Gataullina S,Giordano L,Guerrini R,La Briola F,Mastrangelo M,Mo

    更新日期:2020-12-04 00:00:00

  • Association of circulating metabolites in plasma or serum and risk of stroke: Meta-analysis from seven prospective cohorts.

    abstract:OBJECTIVE:To conduct a comprehensive analysis of circulating metabolites and incident stroke in large prospective population-based settings. METHODS:We investigated the association of metabolites with risk of stroke in seven prospective cohort studies including 1,791 incident stroke events among 38,797 participants in...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011236

    authors: Vojinovic D,Kalaoja M,Trompet S,Fischer K,Shipley MJ,Li S,Havulinna AS,Perola M,Salomaa V,Yang Q,Sattar N,Jousilahti P,Amin N,Satizabal CL,Taba N,Sabayan B,Vasan RS,Ikram MA,Stott DJ,Ala-Korpela M,Jukema JW,Sesh

    更新日期:2020-12-02 00:00:00

  • A clinico-neurophysiological study of urogenital dysfunction in MOG-antibody transverse myelitis.

    abstract:OBJECTIVE:To assess the clinical, urodynamic, and neurophysiologic features of patients with persisting bladder, bowel, and sexual dysfunction after transverse myelitis in myelin oligodendrocyte glycoprotein antibody (MOG-Ab) disease. METHODS:Patients with a history of MOG-Ab disease-related transverse myelitis seen p...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011030

    authors: Li V,Malladi P,Simeoni S,Pakzad M,Everett R,Satukijchai C,Leite MI,Palace J,Panicker JN

    更新日期:2020-11-24 00:00:00

  • PM2.5 associated with gray matter atrophy reflecting increased Alzheimers risk in older women.

    abstract:OBJECTIVE:To examine whether late-life exposure to PM2.5 (particulate matter with aerodynamic diameters <2.5-µm) contributes to progressive brain atrophy predictive of Alzheimer's disease (AD) using a community-dwelling cohort of women (aged 70-89) with up to two brain MRI scans (MRI-1: 2005-6; MRI-2: 2010-11). METHOD...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011149

    authors: Younan D,Wang X,Casanova R,Barnard R,Gaussoin SA,Saldana S,Petkus AJ,Beavers DP,Resnick SM,Manson JE,Serre ML,Vizuete W,Henderson VW,Sachs BC,Salinas JA,Gatz M,Espeland MA,Chui HC,Shumaker SA,Rapp SR,Chen JC,Wom

    更新日期:2020-11-18 00:00:00

  • Increasing Traumatic Brain Injury Incidence during COVID-19 Pandemic in the Emergency Department of Cipto Mangunkusumo National General Hospital-A National Referral Hospital in Indonesia.

    abstract:OBJECTIVE:Evaluating the TBI incidence during the COVID-19 pandemic era compared with similar period in previous year. BACKGROUND:The emergence of SARS-CoV2 influenced the evolution of governmental and hospital policy worldwide, which might eventually impact many aspects. The incidence of many diseases in the Emergenc...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/01.wnl.0000719968.10580.81

    authors: Prawiroharjo P,Pangeran D,Supriawan H,Lastri D,Mayza A,Zairinal RA,Dewi AR,Asmaniar F,Ramli Y

    更新日期:2020-11-17 00:00:00

  • Endothelial and leukocyte-derived microvesicles and cardiovascular risk after stroke-PROSCIS-B.

    abstract:OBJECTIVE:To determine the role of circulating microvesicles (MV) on long-term cardiovascular outcomes after stroke, we measured them in patients with first-ever stroke with a 3-year follow-up. METHODS:In the Prospective Cohort With Incident Stroke Berlin (PROSCIS-B), patients with first-ever ischemic stroke were foll...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011223

    authors: Huo S,Kränkel N,Nave AH,Sperber PS,Rohmann JL,Piper SK,Heuschmann P,Landmesser U,Endres M,Siegerink B,Liman TGG

    更新日期:2020-11-12 00:00:00

  • Association of amyloid-β CSF/PET discordance and tau load 5 years later.

    abstract:OBJECTIVE:To investigate the association between discordant β-amyloid (Aβ) PET and CSF biomarkers at baseline and the emergence of tau pathology 5 years later. METHODS:We included 730 Alzheimer's Disease Neuroimaging Initiative (ADNI) participants without dementia (282 cognitively normal, 448 mild cognitive impairment...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010739

    authors: Reimand J,Collij L,Scheltens P,Bouwman F,Ossenkoppele R,Alzheimer's Disease Neuroimaging Initiative.

    更新日期:2020-11-10 00:00:00

  • Association of vascular brain injury, neurodegeneration, amyloid, and cognitive trajectory.

    abstract:OBJECTIVE:To determine whether vascular and neurodegenerative factors influence cognition before clinically relevant Alzheimer disease pathology, we analyzed MRI measures and amyloid imaging in an ethnoracially diverse cohort of cognitively normal individuals older than 60 years. METHODS:Participants (n = 154; mean ag...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010531

    authors: Han JW,Maillard P,Harvey D,Fletcher E,Martinez O,Johnson DK,Olichney JM,Farias ST,Villeneuve S,Jagust W,Mungas D,DeCarli C

    更新日期:2020-11-10 00:00:00

  • Connections between intrinsically photosensitive retinal ganglion cells and TBI symptoms.

    abstract::The majority of patients with traumatic brain injury (TBI) are classified as having a mild TBI. Despite being categorized as mild, these individuals report ongoing and complex symptoms, which negatively affect their ability to complete activities of daily living and overall quality of life. Some of the major symptoms ...

    journal_title:Neurology

    pub_type: 杂志文章,评审

    doi:10.1212/WNL.0000000000010830

    authors: Elenberger J,Kim B,de Castro-Abeger A,Rex TS

    更新日期:2020-11-03 00:00:00

  • Ictal downbeat nystagmus in Ménière disease: A cross-sectional study.

    abstract:OBJECTIVE:To determine the mechanism of ictal downbeat nystagmus in Ménière disease (MD), we compared the head impulse gain of the vestibulo-ocular reflex (VOR) for each semicircular canal between patients with (n = 7) and without (n = 70) downbeat nystagmus during attacks of MD. METHODS:We retrospectively analyzed th...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010653

    authors: Lee SU,Kim HJ,Choi JY,Kim JS

    更新日期:2020-10-27 00:00:00

  • Time trends in incidence, comorbidity, and mortality of ischemic stroke in Denmark (1996-2016).

    abstract:OBJECTIVE:To examine whether the incidence, comorbidity, and mortality of first-time ischemic stroke changed in Denmark between 1996 and 2016 overall and according to age and sex using a nationwide cohort design. METHODS:In this cohort study, 224,617 individuals ≥18 years of age admitted with first-time ischemic strok...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010647

    authors: Yafasova A,Fosbøl EL,Christiansen MN,Vinding NE,Andersson C,Kruuse C,Johnsen SP,Gislason GH,Torp-Pedersen C,Køber L,Butt JH

    更新日期:2020-10-27 00:00:00

  • Neurologic autoimmunity and immune checkpoint inhibitors: Autoantibody profiles and outcomes.

    abstract:OBJECTIVE:To describe neural autoantibody profiles and outcomes in patients with neurologic autoimmunity associated with immune checkpoint inhibitor (ICI) cancer immunotherapy. METHODS:In this retrospective descriptive study, 63 patients with ICI-related neurologic autoimmunity were included: 39 seen at the Mayo Clini...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010632

    authors: Sechi E,Markovic SN,McKeon A,Dubey D,Liewluck T,Lennon VA,Lopez-Chiriboga AS,Klein CJ,Mauermann M,Pittock SJ,Flanagan EP,Zekeridou A

    更新日期:2020-10-27 00:00:00

  • ANGPTL6 genetic variants are an underlying cause of familial intracranial aneurysms.

    abstract:PURPOSE:To understand the role of the angiopoietin-like 6 gene (ANGPTL6) in intracranial aneurysms (IAs), we investigated its role in a large cohort of familial IAs. METHODS:Individuals with family history of IA were recruited to the Genetic and Observational Subarachnoid Haemorrhage (GOSH) study. The ANGPTL6 gene was...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000011125

    authors: Hostettler IC,O'Callaghan B,Bugiardini E,O'Connor E,Vandrovcova J,Davagnanam I,Alg V,Bonner S,Walsh D,Bulters D,Kitchen N,Brown MM,Grieve J,Werring DJ,Houlden H,Genetics and Observational Subarachnoid Haemorrhage (GOSH) Stu

    更新日期:2020-10-26 00:00:00

  • Education Research: Online Alzheimer education for high school and college students: A randomized controlled trial.

    abstract:OBJECTIVE:Alzheimer disease (AD) risk factors are present throughout the lifespan. This randomized controlled trial evaluated the effectiveness of various online education strategies concerning AD risk reduction and brain health in younger populations. METHOD:High school and college students were recruited via social ...

    journal_title:Neurology

    pub_type: 杂志文章,随机对照试验

    doi:10.1212/WNL.0000000000009859

    authors: Saif N,Niotis K,Dominguez M,Hodes JF,Woodbury M,Amini Y,Sadek G,Scheyer O,Caesar E,Hristov H,Knowlton N,Lee P,McInnis M,Isaacson RS

    更新日期:2020-10-20 00:00:00

  • Sleep, major depressive disorder, and Alzheimer disease: A Mendelian randomization study.

    abstract:OBJECTIVE:To explore the causal relationships between sleep, major depressive disorder (MDD), and Alzheimer disease (AD). METHODS:We conducted bidirectional 2-sample Mendelian randomization analyses. Genetic associations were obtained from the largest genome-wide association studies currently available in UK Biobank (...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010463

    authors: Huang J,Zuber V,Matthews PM,Elliott P,Tzoulaki J,Dehghan A

    更新日期:2020-10-06 00:00:00

  • Sex, race, and risk of dementia diagnosis after traumatic brain injury among older veterans.

    abstract:OBJECTIVE:To investigate whether sex and race differences exist in dementia diagnosis risk associated with traumatic brain injury (TBI) among older veterans. METHODS:Using Fine-Gray regression models, we investigated incident dementia diagnosis risk with TBI exposure by sex and race. RESULTS:After the exclusion of ba...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010617

    authors: Kornblith E,Peltz CB,Xia F,Plassman B,Novakovic-Apopain T,Yaffe K

    更新日期:2020-09-29 00:00:00

  • Pediatric Multiple Sclerosis Severity Score in a large US cohort.

    abstract:OBJECTIVE:To characterize disease severity and distribution of disability in pediatric-onset multiple sclerosis (POMS) and to develop an optimized modeling scale for measuring disability, we performed a multicenter retrospective analysis of disability scores in 873 persons with POMS over time and compared this to previ...

    journal_title:Neurology

    pub_type: 杂志文章,多中心研究

    doi:10.1212/WNL.0000000000010414

    authors: Santoro JD,Waltz M,Aaen G,Belman A,Benson L,Gorman M,Goyal MS,Graves JS,Harris Y,Krupp L,Lotze T,Mar S,Moodley M,Ness J,Rensel M,Rodriguez M,Schreiner T,Tillema JM,Waubant E,Weinstock-Guttman B,Hurtubise BF,Roal

    更新日期:2020-09-29 00:00:00

  • Prospective observational cohort study of early recurrent TIA: Features, frequency, and outcome.

    abstract:OBJECTIVES:To evaluate the frequency, clinical and etiologic features, and short- and long-term outcomes of early recurrent TIA. METHODS:This prospective observational cohort study enrolled all consecutive patients with TIA referred to our emergency department and diagnosed by a vascular neurologist. Expedited assessm...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010317

    authors: Foschi M,Pavolucci L,Rondelli F,Spinardi L,Favaretto E,Filippini M,Degli Esposti D,Strocchi E,Faggioli G,Cortelli P,Guarino M,Bologna TIA Study-Group.

    更新日期:2020-09-22 00:00:00

  • Patient-acceptable symptom states in myasthenia gravis.

    abstract:OBJECTIVES:To estimate patient-acceptable symptom state (PASS) cut points for myasthenia gravis (MG) health scales. METHODS:We conducted an electronic survey that included the Myasthenia Gravis Impairment Index (MGII), EuroQol 5-Dimension (EQ5D), and a simple PASS question. PASS-anchored thresholds were estimated for ...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010574

    authors: Mendoza M,Tran C,Bril V,Katzberg HD,Barnett C

    更新日期:2020-09-22 00:00:00

  • Clinician-judged hearing impairment and associations with neuropathologic burden.

    abstract:OBJECTIVE:To examine whether neuropathologic burden is associated with hearing impairment. METHODS:We studied 2,755 autopsied participants ≥55 years of age from the National Alzheimer's Coordinating Center database. Participants had at least 1 clinical evaluation at US National Institute on Aging-funded Alzheimer's Di...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010575

    authors: Brenowitz WD,Besser LM,Kukull WA,Keene CD,Glymour MM,Yaffe K

    更新日期:2020-09-22 00:00:00

  • Multitracer model for staging cortical amyloid deposition using PET imaging.

    abstract:OBJECTIVE:To develop and evaluate a model for staging cortical amyloid deposition using PET with high generalizability. METHODS:Three thousand twenty-seven individuals (1,763 cognitively unimpaired [CU], 658 impaired, 467 with Alzheimer disease [AD] dementia, 111 with non-AD dementia, and 28 with missing diagnosis) fr...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010256

    authors: Collij LE,Heeman F,Salvadó G,Ingala S,Altomare D,de Wilde A,Konijnenberg E,van Buchem M,Yaqub M,Markiewicz P,Golla SSV,Wottschel V,Wink AM,Visser PJ,Teunissen CE,Lammertsma AA,Scheltens P,van der Flier WM,Boellaard R

    更新日期:2020-09-15 00:00:00

  • Cerebrovascular reactivity in cerebral amyloid angiopathy, Alzheimer disease, and mild cognitive impairment.

    abstract:OBJECTIVE:To assess cerebrovascular reactivity in response to a visual task in participants with cerebral amyloid angiopathy (CAA), Alzheimer disease (AD), and mild cognitive impairment (MCI) using fMRI. METHODS:This prospective cohort study included 40 patients with CAA, 22 with AD, 27 with MCI, and 25 healthy contro...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010201

    authors: Switzer AR,Cheema I,McCreary CR,Zwiers A,Charlton A,Alvarez-Veronesi A,Sekhon R,Zerna C,Stafford RB,Frayne R,Goodyear BG,Smith EE

    更新日期:2020-09-08 00:00:00

  • Blood biomarkers of traumatic brain injury and cognitive impairment in older veterans.

    abstract:OBJECTIVE:To determine whether blood-based biomarkers can differentiate older veterans with and without traumatic brain injury (TBI) and cognitive impairment (CogI). METHODS:We enrolled 155 veterans from 2 veterans' retirement homes: 90 without TBI and 65 with TBI history. Participants were further separated into CogI...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010087

    authors: Peltz CB,Kenney K,Gill J,Diaz-Arrastia R,Gardner RC,Yaffe K

    更新日期:2020-09-01 00:00:00

  • Association of retinal layer measurements and adult cognitive function: A population-based study.

    abstract:OBJECTIVE:To quantify the associations of peripapillary retinal nerve fiber layer (pRNFL) thickness and macular ganglion cell layer (mGCL) volume with cognitive functioning and to investigate how demographic and vascular health factors affect these associations in a population-based sample of adults. METHODS:The sampl...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010146

    authors: Ward DD,Mauschitz MM,Bönniger MM,Merten N,Finger RP,Breteler MMB

    更新日期:2020-09-01 00:00:00

  • Prevalence of MRI abnormalities in people with epilepsy in rural China.

    abstract:OBJECTIVE:To assess the prevalence of brain MRI abnormalities in people with epilepsy in rural China and to compare it with that of individuals in the United Kingdom. METHODS:Brain MRI scans were obtained in people with epilepsy who participated in a rural community-based program in China between July 2010 and Decembe...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010171

    authors: Davagnanam I,Chen Z,Hoskote C,Ding D,Yang B,Wang Y,Wang T,Li W,Duncan JS,Wang W,Sander JW,Kwan P

    更新日期:2020-09-01 00:00:00

  • Familial language network vulnerability in primary progressive aphasia.

    abstract:OBJECTIVE:To investigate evidence of the potential role of early cortical vulnerability in the development of primary progressive aphasia (PPA). METHOD:A woman with a diagnosis of PPA and her 9 adult siblings, 7 with developmental language disabilities, underwent neuropsychological testing, structural MRI, and resting...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000009842

    authors: Weintraub S,Rader B,Coventry C,Sridhar J,Wood J,Guillaume KA,Coppola G,Ramos EM,Bonakdarpour B,Rogalski EJ,Mesulam MM

    更新日期:2020-08-18 00:00:00

  • Mortality among patients with idiopathic intracranial hypertension enrolled in the IH Registry.

    abstract:OBJECTIVE:To determine (1) if mortality among patients with idiopathic intracranial hypertension (IIH) enrolled in the Intracranial Hypertension Registry (IHR) is different from that of the general population of the United States and (2) what the leading underlying causes of death are among this cohort. METHODS:Mortal...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000009312

    authors: Hermes SM,Miller NR,Waslo CS,Benes SC,Tanne E

    更新日期:2020-08-18 00:00:00

  • Effect of herpes zoster vaccine and antiviral treatment on risk of ischemic stroke.

    abstract:OBJECTIVE:To determine whether increased risk of acute ischemic stroke (AIS) following herpes zoster (HZ) might be modified by the status of zoster vaccine live (ZVL) vaccination and antiviral treatment following HZ. METHODS:We included 87,405 Medicare fee-for-service beneficiaries aged ≥66 years diagnosed with HZ and...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000010028

    authors: Yang Q,George MG,Chang A,Tong X,Merritt R,Hong Y

    更新日期:2020-08-11 00:00:00

  • Incidence of first seizures, epilepsy, and seizure mimics in a geographically defined area.

    abstract:OBJECTIVE:To determine the incidence of first seizures, epilepsy, and seizure mimics in a geographically defined area using the updated 2014 International League Against Epilepsy (ILAE) definition, which allows an epilepsy diagnosis after a single seizure when the risk of further seizures over the next 10 years is ≈60%...

    journal_title:Neurology

    pub_type: 杂志文章

    doi:10.1212/WNL.0000000000009980

    authors: Maloney EM,Chaila E,O'Reilly ÉJ,Costello DJ

    更新日期:2020-08-04 00:00:00

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