abstract：:The purpose of this review is to describe our management approach to patients with treatment-emergent central sleep apnea (TECSA). The emergence of central sleep apnea during positive airway pressure therapy occurs in approximately 8% of titration studies for obstructive sleep apnea, and has been associated with sever...

journal_title：Chest

authors： Zeineddine S,Badr MS

更新日期：2021-01-23 00:00:00

abstract：BACKGROUND:CPAP effectiveness is limited by suboptimal adherence. Prior studies of adherence have focused on middle-aged men. RESEARCH QUESTION:Does CPAP adherence vary by age and sex? STUDY DESIGN AND METHODS:Telemonitoring data from a CPAP manufacturer database were used to assess adherence in patients initiating C...

journal_title：Chest

authors： Patel SR,Bakker JP,Stitt CJ,Aloia MS,Nouraie SM

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The presence and progression of interstitial lung abnormalities (ILAs) is known to be associated with a decline of lung function and increased risk of mortality. RESEARCH QUESTION:We aimed to elucidate the clinical course according to ILAs in patients with COPD. STUDY DESIGN AND METHODS:A retrospective stu...

journal_title：Chest

authors： Lee TS,Jin KN,Lee HW,Yoon SY,Park TY,Heo EY,Kim DK,Chung HS,Lee JK

更新日期：2021-01-01 00:00:00

abstract：CASE PRESENTATION:A 2-year-old boy was referred to the Ankara University School of Medicine Children's Hospital with a history of recurrent respiratory distress and cyanosis since birth. His medical history was significant for premature birth at 31 weeks via cesarean section, as an infant of a diabetic mother. There wa...

journal_title：Chest

authors： Zirek F,Akova BŞ,Özcan G,Fitoz S,Çobanoğlu N

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The Centers for Medicare and Medicaid Services stipulate shared decision-making (SDM) counseling as a prerequisite to lung cancer screening (LCS) reimbursement, despite well-known challenges implementing SDM in practice. RESEARCH QUESTION:How have health-care organizations implemented SDM for LCS? STUDY DE...

journal_title：Chest

authors： Alishahi Tabriz A,Neslund-Dudas C,Turner K,Rivera MP,Reuland DS,Elston Lafata J

更新日期：2021-01-01 00:00:00

abstract：:All aspects of medical education were affected by the Novel Coronavirus Infectious Disease-19 (COVID-19) pandemic. Several challenges were experienced by trainees and programs alike due to the economic repercussions of the pandemic, how social distancing affected the delivery of medical education, testing and intervie...

journal_title：Chest

authors： Kaul V,Gallo de Moraes A,Khateeb D,Greenstein Y,Winter G,Chae J,Stewart NH,Qadir N,Dangayach NS

更新日期：2020-12-29 00:00:00

abstract：:To assess airway and lung parenchymal damage non-invasively in cystic fibrosis (CF), chest MRI has been historically out of the scope of routine clinical imaging due to technical difficulties such as the low proton density and respiratory and cardiac motion. However, technological breakthroughs have recently emerged t...

journal_title：Chest

authors： Dournes G,Walkup LL,Benlala I,Willmering MM,Macey J,Bui S,Laurent F,Woods JC

更新日期：2020-12-17 00:00:00

abstract：BACKGROUND:During medical procedures with the potential to produce aerosols such as bronchoscopy, intubation, or CPR, health-care workers (HCWs) may be exposed to infectious bioaerosols. This scenario is of particular concern when high consequence pathogens such as severe acute respiratory syndrome coronavirus 2 (SARS-...

journal_title：Chest

authors： Doggett N,Chow CW,Mubareka S

更新日期：2020-12-01 00:00:00

abstract：CASE PRESENTATION:A 69-year-old man consulted for a 3-day history of fever, wet cough, and yellow-green phlegm. He denied having any dyspnea, chest pain, hemoptysis, swallowing disorders, choke, chills, asthenia, anorexia, or weight loss. He reported a continuous dry cough and three episodes of pneumonia in the past 4 ...

journal_title：Chest

authors： Hoan L,Hang LM,Thanh Hong DT,Nhu Quynh NT,Linh LT,Cuong NN,Minh TN,Luan DT,Thang ND,Delphine N

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:There is an increasing demand for home mechanical ventilation (HMV) in patients with chronic respiratory insufficiency. At present, noninvasive ventilation is exclusively initiated in a clinical setting at all four centers for HMV in the Netherlands. In addition to its high societal costs and patient discomf...

journal_title：Chest

authors： van den Biggelaar RJM,Hazenberg A,Cobben NAM,Gaytant MA,Vermeulen KM,Wijkstra PJ

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Individual studies have reported widely variable rates for VTE and bleeding among hospitalized patients with coronavirus disease 2019 (COVID-19). RESEARCH QUESTION:What is the incidence of VTE and bleeding among hospitalized patients with COVID-19? METHODS:In this systematic review and meta-analysis, 15 st...

journal_title：Chest

authors： Jiménez D,García-Sanchez A,Rali P,Muriel A,Bikdeli B,Ruiz-Artacho P,Le Mao R,Rodríguez C,Hunt BJ,Monreal M

更新日期：2020-11-17 00:00:00

abstract：BACKGROUND:Institutional-level disparities in non-small cell lung cancer (NSCLC) survival may be driven by reversible differences in care-delivery processes. We quantified the impact of differences in readily identifiable quality metrics on long-term survival disparities in resected NSCLC. RESEARCH QUESTION:How do rev...

journal_title：Chest

authors： Osarogiagbon RU,Sineshaw HM,Lin CC,Jemal A

更新日期：2020-11-14 00:00:00

abstract：:Exertional dyspnea is a common complaint for patients seen in pulmonary, cardiac, and general medicine clinics, and elucidating the cause is often challenging, particularly when physical examination, echocardiography, radiography, and pulmonary function test results are inconclusive. Invasive cardiopulmonary exercise ...

journal_title：Chest

authors： Jain CC,Borlaug BA

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Physicians play a crucial role in providing smoking cessation counseling and medications. However, it is unknown whether individual physicians' approaches affect whether patients quit. RESEARCH QUESTION:This study assessed patient quit rates within a national quality-improvement learning collaborative to do...

journal_title：Chest

authors： Almaaitah S,Ciemins EL,Joshi V,Arora A,Meskow C,Rothberg MB

更新日期：2020-11-01 00:00:00

abstract：:A 40-year-old woman with lymphangiomatosis also had an intrathoracic lymphangioma infection. Since the age of 8 years, the patient had undergone repeated abdominal and mediastinal cyst surgeries and had received a diagnosis of lymphangiomatosis. At this time, she showed a high fever of 38.5°C. Cultures of both blood a...

journal_title：Chest

authors： Minakata T,Suzuki T,Kamio Y,Kadokura M,Himuro N,Takei H

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Studies have demonstrated that high-flow nasal cannula (HFNC) prevents intubation in acute hypoxic respiratory failure when compared with conventional oxygen therapy (COT). However, the data examining routine HFNC use in the immediate postoperative period are less clear. RESEARCH QUESTION:Is routine HFNC us...

journal_title：Chest

authors： Chaudhuri D,Granton D,Wang DX,Burns KEA,Helviz Y,Einav S,Trivedi V,Mauri T,Ricard JD,Mancebo J,Frat JP,Jog S,Hernandez G,Maggiore SM,Mbuagbaw L,Hodgson CL,Jaber S,Goligher EC,Brochard L,Rochwerg B

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Excessive daytime sleepiness (EDS) in individuals with OSA syndrome persisting despite good adherence to CPAP is a disabling condition. Pitolisant is a selective histamine H3-receptor antagonist with wake-promoting effects. RESEARCH QUESTION:Is pitolisant effective and safe for reducing daytime sleepiness i...

journal_title：Chest

authors： Pépin JL,Georgiev O,Tiholov R,Attali V,Verbraecken J,Buyse B,Partinen M,Fietze I,Belev G,Dokic D,Tamisier R,Lévy P,Lecomte I,Lecomte JM,Schwartz JC,Dauvilliers Y,HAROSA I Study Group.

更新日期：2020-10-26 00:00:00

abstract：:In recent months, medical institutions across the United States redoubled their efforts to examine the history of race and racism in medicine, in classrooms, in research, and in clinical practice. In this essay, I explore the history of racialization of the spirometer, a widely used instrument in pulmonary medicine to...

journal_title：Chest

authors： Braun L

更新日期：2020-10-24 00:00:00

abstract：BACKGROUND:Guidelines are critical for facilitating cost-effective COPD care. Development and implementation in low-and middle-income countries (LMICs) is challenging. To guide future strategy, an overview of current global COPD guidelines is required. RESEARCH QUESTION:We systematically reviewed national COPD guideli...

journal_title：Chest

authors： Tabyshova A,Hurst JR,Soriano JB,Checkley W,Wan-Chun Huang E,Trofor AC,Flores-Flores O,Alupo P,Gianella G,Ferdous T,Meharg D,Alison J,Correia de Sousa J,Postma MJ,Chavannes NH,van Boven JFM

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Kidney disease has been linked to risk for hospitalization-related (HR) VTE, but the effect size and differences across types of kidney disease are described poorly. RESEARCH QUESTION:Can the risk for HR VTE among patients with acute kidney injury (AKI) and chronic kidney disease be quantified, and if so, h...

journal_title：Chest

authors： McMahon MMJ,Collen LPJF,Chung CKK,Stewart LIJ,Haydar L,Moores CRLK,Holley CAB

更新日期：2020-10-05 00:00:00

abstract：:Infection with the severe acute respiratory syndrome coronavirus 2 causes severe acute lung injury in approximately 5% of infected adults, but few reports have been made of severe pediatric disease. We present an adolescent patient who contracted severe acute respiratory syndrome coronavirus 2 one week after a paterna...

journal_title：Chest

authors： Fisler G,Haimed A,Levy CF,Stiles J,Capone CA,Fish JD,Brochstein JA,Taylor MD

更新日期：2020-10-01 00:00:00

abstract：:Pulmonary hypertension (PH) due to interstitial lung disease (ILD; PH-ILD) can complicate a multitude of ILDs, including idiopathic pulmonary fibrosis, chronic hypersensitivity pneumonitis, and nonspecific interstitial pneumonia. Development of PH-ILD is associated with increased need for supplemental oxygen, reduced ...

journal_title：Chest

authors： King CS,Shlobin OA

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Bronchoscopy is a useful tool for the diagnosis of lesions near central airways; however, the diagnostic accuracy of these procedures for peripheral pulmonary lesions (PPLs) is a matter of ongoing debate. In this setting, electromagnetic navigation bronchoscopy (ENB) is a technique used to navigate and obtai...

journal_title：Chest

authors： Folch EE,Labarca G,Ospina-Delgado D,Kheir F,Majid A,Khandhar SJ,Mehta HJ,Jantz MA,Fernandez-Bussy S

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:To address the burden of tobacco use in underserved populations, our safety net hospital developed a tobacco treatment intervention consisting of an "opt-out" electronic health record-based best practice alert + order set, which triggers consultation to an inpatient tobacco treatment consult (TTC) service fo...

journal_title：Chest

authors： Herbst N,Wiener RS,Helm ED,O'Donnell C,Fitzgerald C,Wong C,Bulekova K,Waite M,Mishuris RG,Kathuria H

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:In patients with bronchiectasis, airway clearance techniques (ACTs) are important management strategies. RESEARCH QUESTION:What are the differences in patients with bronchiectasis and a productive cough who used ACTs and those who did not? What was the assessment of bronchiectasis exacerbation frequency and...

journal_title：Chest

authors： Basavaraj A,Choate R,Addrizzo-Harris D,Aksamit TR,Barker A,Daley CL,Anne Daniels ML,Eden E,DiMango A,Fennelly K,Griffith DE,Johnson MM,Knowles MR,Metersky ML,Noone PG,O'Donnell AE,Olivier KN,Salathe MA,Schmid A,Thom

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Black smokers have earlier development of lung disease as well as poorer sleep health than whites. RESEARCH QUESTION:In a sample of black smokers, to what extent does sleep health modify the association between smoking level and functional exercise capacity? DESIGN AND METHODS:Cross-sectional data from 209...

journal_title：Chest

authors： Gangemi AJ,Satti A,Zantah M,Blair R,Brewer B,Ma G,Grandner MA,Davey A,Criner GJ,Patterson F

更新日期：2020-10-01 00:00:00

abstract：:Although nearly 3,000 e-cigarette-related hospitalizations have been reported in North America, the long-term outcomes in these patients have not been described. We followed an 18-year-old boy who survived acute critical illness and respiratory failure related to 5 months of e-cigarette use. Chronic irreversible airfl...

journal_title：Chest

authors： Eddy RL,Serajeddini H,Knipping D,Landman ST,Bosma KJ,Mackenzie CA,Dhaliwal I,Parraga G

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Strong evidence exists for clinically relevant night-to-night variability of respiratory events in patients with suspected OSA. RESEARCH QUESTION:How many sleep study nights are required to diagnose OSA accurately? STUDY DESIGN AND METHODS:Patients with suspected OSA underwent up to 14 nights of pulse oxim...

journal_title：Chest

authors： Roeder M,Sievi NA,Bradicich M,Grewe F,Siegfried S,Gaisl T,Kohler M

更新日期：2020-09-25 00:00:00

abstract：BACKGROUND:Chronic tobacco smoke exposure results in a broad range of lung pathologies including emphysema, airway disease and parenchymal fibrosis as well as a multitude of extra-pulmonary comorbidities. Prior work using CT imaging has identified several clinically relevant subgroups of smoking related lung disease, b...

journal_title：Chest

authors： Billatos E,Ash SY,Duan F,Xu K,Romanoff J,Marques H,Moses E,Han MK,Regan EA,Bowler RP,Mason SE,Doyle TJ,San José Estépar R,Rosas IO,Ross JC,Xiao X,Liu H,Liu G,Sukumar G,Wilkerson M,Dalgard C,Stevenson C,Whitney

更新日期：2020-09-16 00:00:00

abstract：BACKGROUND:Self-reported tobacco pack-year history plays a large role in decisions about low-dose CT screening for lung cancer, yet is challenging to measure accurately. RESEARCH QUESTION:To what extent does random measurement error in pack-year information impact screening decisions and screening effectiveness? STUD...

journal_title：Chest

authors： Caverly TJ,Zhang X,Hayward RA,Zhu J,Waljee AK

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:The coronavirus disease 2019 (COVID-19) pandemic has severely affected ICUs and critical care health-care providers (HCPs) worldwide. RESEARCH QUESTION:How do regional differences and perceived lack of ICU resources affect critical care resource use and the well-being of HCPs? STUDY DESIGN AND METHODS:Betw...

journal_title：Chest

authors： Wahlster S,Sharma M,Lewis AK,Patel PV,Hartog CS,Jannotta G,Blissitt P,Kross EK,Kassebaum NJ,Greer DM,Curtis JR,Creutzfeldt CJ

更新日期：2020-09-11 00:00:00

abstract：BACKGROUND:A paucity of studies have assessed the epidemiology of community-acquired pneumonia (CAP) that require ICU admission. We conducted a study on this group of patients with the primary objective of defining the incidence, epidemiology, and mortality rate of CAP in the ICUs in Louisville, Kentucky. The secondary...

journal_title：Chest

authors： Cavallazzi R,Furmanek S,Arnold FW,Beavin LA,Wunderink RG,Niederman MS,Ramirez JA

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Vasodilatory shock refractory to catecholamine vasopressors and arginine vasopressin is highly morbid and responsible for significant mortality. Synthetic angiotensin II is a potent vasoconstrictor that may be suitable for use in these patients. RESEARCH QUESTION:What is the safety and effectiveness of angi...

journal_title：Chest

authors： Wieruszewski PM,Wittwer ED,Kashani KB,Brown DR,Butler SO,Clark AM,Cooper CJ,Davison DL,Gajic O,Gunnerson KJ,Tendler R,Mara KC,Barreto EF

更新日期：2020-08-31 00:00:00

abstract：BACKGROUND:Mepolizumab was the first licensed anti-IL5 monoclonal antibody for severe eosinophilic asthma (SEA). To date there are few data to confirm its efficacy in the real-world setting or assessment of baseline characteristics associated with response. RESEARCH QUESTION:How do patients with severe eosinophilic as...

journal_title：Chest

authors： Kavanagh JE,d'Ancona G,Elstad M,Green L,Fernandes M,Thomson L,Roxas C,Dhariwal J,Nanzer AM,Kent BD,Jackson DJ

更新日期：2020-08-01 00:00:00

abstract：:Health systems confronting the coronavirus disease 2019 (COVID-19) pandemic must plan for surges in ICU demand and equitably distribute resources to maximize benefit for critically ill patients and the public during periods of resource scarcity. For example, morbidity and mortality could be mitigated by a proactive re...

journal_title：Chest

authors： Prekker ME,Brunsvold ME,Bohman JK,Fischer G,Gram KL,Litell JM,Saavedra-Romero R,Hick JL

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Little is known about the prevalence, predictors, and outcomes of late vasopressor administration which evolves after admission to the ICU. RESEARCH QUESTION:What is the epidemiology of late vasopressor administration in the ICU? STUDY DESIGN AND METHODS:We retrospectively studied a cohort of veterans admi...

journal_title：Chest

authors： Viglianti EM,Bagshaw SM,Bellomo R,McPeake J,Molling DJ,Wang XQ,Seelye S,Iwashyna TJ

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Participant retention is a major challenge in clinical research, especially in studies with multiple, longitudinal research assessments. Despite the importance of retention methods, there is little empirical research on how cohort retention efforts are perceived by study participants. RESEARCH QUESTION:To e...

journal_title：Chest

authors： Eakin MN,Eckmann T,Dinglas VD,Akinremi AA,Hosey M,Hopkins RO,Needham DM

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Interstitial lung disease (ILD) results in high morbidity and health-care utilization. Diagnostic delays remain common and often occur in nonpulmonology settings. Screening for ILD in these settings has the potential to reduce diagnostic delays and improve patient outcomes. RESEARCH QUESTION:This study soug...

journal_title：Chest

authors： Pugashetti JV,Kitich A,Alqalyoobi S,Maynard-Paquette AC,Pritchard D,Graham J,Boctor N,Kulinich A,Lafond E,Foster E,Mendez C,Choudhry S,Chalaoui J,Morisset J,Kadoch M,Oldham JM

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Long-term outcomes of awakened survivors of out-of-hospital cardiac arrest (OHCA) are poorly known. RESEARCH QUESTION:What are the month (M) 18 outcomes of survivors of out-of-hospital cardiac arrest (OHCA) who awakened during the first 2 weeks' post-OHCA and their poor-outcome risk factors? STUDY DESIGN A...

journal_title：Chest

authors： Peskine A,Cariou A,Hajage D,Deye N,Guérot E,Dres M,Sonneville R,Lafourcade A,Navarro V,Robert H,Azouvi P,Sharshar T,Bayen E,Luyt CE,Hanox Study Group.

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:COPD is a heterogeneous disease demonstrating inter-individual variation. A high COPD prevalence in Chinese populations is described, but little is known about disease clusters and prognostic outcomes in the Chinese population across Southeast Asia. We aim to determine if clusters of Chinese patients with CO...

journal_title：Chest

authors： Tiew PY,Ko FWS,Narayana JK,Poh ME,Xu H,Neo HY,Loh LC,Ong CK,Mac Aogáin M,Tan JHY,Kamaruddin NH,Sim GJH,Lapperre TS,Koh MS,Hui DSC,Abisheganaden JA,Tee A,Tsaneva-Atanasova K,Chotirmall SH

更新日期：2020-07-01 00:00:00