abstract：BACKGROUND:Imerslund-Gräsbeck syndrome is a rare genetic disease characterised by vitamin B12 deficiency and proteinuria. CASE PRESENTATION:A 4-year old Sri Lankan boy presented with gradually worsening difficulty in walking for two weeks duration. He was previously diagnosed and managed as having non-transfusion-depe...

journal_title：BMC pediatrics

authors： Arunath V,Hoole TJ,Rathnasri A,Muthukumarana O,Kumarasiri IM,Liyanage ND,Costa Y,Mettananda S

更新日期：2021-01-18 00:00:00

abstract：BACKGROUND:Because of the absence of a specific diagnostic test and pathognomonic clinical features, physicians must rely on the presence of specific clinical criteria and laboratory data that support the diagnosis of KD. To help clinicians distinguish KD, KDSS, septic shock, and TSS earlier, we suggest differential di...

journal_title：BMC pediatrics

authors： Park WY,Lee SY,Kim GB,Song MK,Kwon HW,Bae EJ,Choi EH,Park JD

更新日期：2021-01-08 00:00:00

abstract：BACKGROUND:Intestinal lymphangiectasia is a rare disease. Thus, prospective studies are impossible, and therapy is still controversial. Several medicines are suggested for treatment but there are no existing indications for drug choice and treatment guidelines. We aimed to introduce the action mechanism of each drug an...

journal_title：BMC pediatrics

authors： Kwon Y,Kim ES,Choe YH,Kim MJ

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:We propose a modified lung ultrasound (LUS) score in neonates with respiratory distress syndrome (RDS), which includes posterior instead of lateral lung fields, and a 5-grade rating scale instead of a 4-grade rating scale. The purpose of this study was to evaluate the reproducibility of the rating scale and ...

journal_title：BMC pediatrics

authors： Szymański P,Kruczek P,Hożejowski R,Wais P

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:Coronavirus disease 2019 (COVID-19) has impacted the provision of health services in all specialties. We aim to study the impact of COVID-19 on the utilization of pediatric hospital services including emergency department (ED) attendances, hospitalizations, diagnostic categories and resource utilization in S...

journal_title：BMC pediatrics

authors： Chong SL,Soo JSL,Allen JC Jr,Ganapathy S,Lee KP,Tyebally A,Yung CF,Thoon KC,Ng YH,Oh JY,Teoh OH,Mok YH,Chan YH

更新日期：2020-12-23 00:00:00

abstract：BACKGROUND:Children with a history of caustic or foreign body ingestion (FBI) seem to be presenting more frequently to emergency departments. This study aims to elucidate the clinical presentation, diagnostic procedures, and complications associated with the ingestion of different object categories over a 13-year time ...

journal_title：BMC pediatrics

authors： Speidel AJ,Wölfle L,Mayer B,Posovszky C

更新日期：2020-12-18 00:00:00

abstract：BACKGROUND:Bazett formula is frequently used in paediatric screening for the long QT syndrome (LQTS) and proposals exist that using standing rather than supine electrocardiograms (ECG) improves the sensitivity of LQTS diagnosis. Nevertheless, compared to adults, children have higher heart rates (especially during postu...

journal_title：BMC pediatrics

authors： Andršová I,Hnatkova K,Helánová K,Šišáková M,Novotný T,Kala P,Malik M

更新日期：2020-12-14 00:00:00

abstract：BACKGROUND:Necrotizing enterocolitis (NEC) is a devastating disease that is relatively frequently diagnosed in term infants with congenital heart disease (CHD), compared with term infants without CHD, in whom NEC is rare. The exact pathogenesis of NEC in term infants with CHD is unknown, but it is hypothesized that isc...

journal_title：BMC pediatrics

authors： van der Heide M,Mebius MJ,Bos AF,Roofthooft MTR,Berger RMF,Hulscher JBF,Kooi EMW

更新日期：2020-12-07 00:00:00

abstract：BACKGROUND:Maternal iodine requirements increase during pregnancy to supply thyroid hormones essential for fetal brain development. Maternal iodine deficiency can lead to hypothyroxinemia, a reduced fetal supply of thyroid hormones which, in the first trimester, has been linked to an increased risk of autism spectrum d...

journal_title：BMC pediatrics

authors： Cromie KJ,Threapleton DE,Snart CJP,Taylor E,Mason D,Wright B,Kelly B,Reid S,Azad R,Keeble C,Waterman AH,Meadows S,McKillion A,Alwan NA,Cade JE,Simpson NAB,Stewart PM,Zimmermann M,Wright J,Waiblinger D,Mon-Williams

更新日期：2020-12-05 00:00:00

abstract：BACKGROUND:Medication Errors (MEs) are considered the most common type of error in pediatric critical care services. Moreover, the ME rate in pediatric patients is up to three times higher than the rate for adults. Nevertheless, information in pediatric population is still limited, particularly in emergency/critical ca...

journal_title：BMC pediatrics

authors： Brennan-Bourdon LM,Vázquez-Alvarez AO,Gallegos-Llamas J,Koninckx-Cañada M,Marco-Garbayo JL,Huerta-Olvera SG

更新日期：2020-12-05 00:00:00

abstract：BACKGROUND:Parents of infants in neonatal intensive care units (NICUs) are often unintentionally marginalized in pursuit of optimal clinical care. Family Integrated Care (FICare) was developed to support families as part of their infants' care team in level III NICUs. We adapted the model for level II NICUs in Alberta,...

journal_title：BMC pediatrics

authors： Benzies KM,Aziz K,Shah V,Faris P,Isaranuwatchai W,Scotland J,Larocque J,Mrklas KJ,Naugler C,Stelfox HT,Chari R,Soraisham AS,Akierman AR,Phillipos E,Amin H,Hoch JS,Zanoni P,Kurilova J,Lodha A,Alberta FICare Level II

更新日期：2020-11-28 00:00:00

abstract：BACKGROUND:Hemiscrotal agenesis (HSA) is an exceedingly rare congenital anomaly in scrotal development. It is characterized by unilateral absence of scrotal skin with intact midline raphe. In the English literature, only seven patients were diagnosed with HSA. Herein, we report a 14-month-old boy with HSA, unilateral c...

journal_title：BMC pediatrics

authors： Mansy M,Kotb M,Abdelmeguid Y,Raafat S,Abdelaziz M

更新日期：2020-11-28 00:00:00

abstract：BACKGROUND:This report summarizes the clinical characteristics of intractable anemia as part of the clinical presentation of Hirschsprung's disease (HD) and aims to strengthen clinicians' ability to recognize early signs of HD. CASE PRESENTATION:An 11-year-old boy with a 6-year history of intractable anemia, low hemog...

journal_title：BMC pediatrics

authors： Sun X,Chu J,Li C,Deng Z

更新日期：2020-11-16 00:00:00

abstract：BACKGROUND:Childhood apraxia of speech (CAS) is a neurodevelopmental disorder with heterogeneous communication and other comorbid manifestations. While previous studies have characterized speech deficits associated with CAS, few studies have examined variability in reading and language and/or other developmental comorb...

journal_title：BMC pediatrics

authors： Stein CM,Benchek P,Miller G,Hall NB,Menon D,Freebairn L,Tag J,Vick J,Taylor HG,Lewis BA,Iyengar SK

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:The Pediatric Quality of Life Inventory (PedsQL) is a modular instrument, designed to integrate generic and disease specific measures, and includes both self- and proxy-reports. The aim of the study was to assess the reliability and limited validity of the Swedish version of the disease specific Pediatric Qu...

journal_title：BMC pediatrics

authors： Sand P,Kleiberg AN,Kljajić M,Lannering B

更新日期：2020-10-28 00:00:00

abstract：BACKGROUND:Ehlers-Danlos syndrome (EDS) is a group of inherited connective tissue disorders characterized by skin hyperextensibility, joint hypermobility and soft tissue vulnerable to blunt injury. Early recognition and diagnosis are crucial to patients to provide appropriate treatment, as well as to screen for life-th...

journal_title：BMC pediatrics

authors： Chiu WC,Chen SH,Lo MC,Kuo YT

更新日期：2020-10-27 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via the original article. ...

journal_title：BMC pediatrics

authors： Canty EA,Fogel BN,Batra EK,Schaefer EW,Beiler JS,Paul IM

更新日期：2020-10-24 00:00:00

abstract：BACKGROUND:Concepts such as participation and environment may differ across cultures. Consequently, to use a measure like the Participation and Environment Measure for Children and Youth (PEM-CY) in other than the original English-speaking contexts, cultural adaptation needs to be assured. The aim of this study was to ...

journal_title：BMC pediatrics

authors： Krieger B,Schulze C,Boyd J,Amann R,Piškur B,Beurskens A,Teplicky R,Moser A

更新日期：2020-10-24 00:00:00

abstract：BACKGROUND:Rosai- Dorfman Disease (RDD) is a benign condition of unknown aetiology which is characterized by non-neoplastic proliferation of histiocytes. Pathophysiology and natural history remain obscure due to the low prevalence of disease. It is known to present with nodal or extranodal involvement and occurrence in...

journal_title：BMC pediatrics

authors： Danisious T,Hettiarachchi M,Dharmadasa C,Jayaweera H

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:There is growing concern as regards the emergence of metabolic disorders among children living with the Human Immunodeficiency Virus (HIV) worldwide. However, there is paucity of data on the correlates of metabolic indices among HIV-positive children in Africa. METHODS:This study examined 84 HIV-positive ch...

journal_title：BMC pediatrics

authors： Ohuche IO,Chikani UN,Oyenusi EE,Onu JU,Oduwole A

更新日期：2020-10-02 00:00:00

abstract：BACKGROUND:The Global Trigger Tool (GTT),which is a method using "triggers" to review medical record retrospectively to identify possible adverse events. Several studies showed that the GTT was effective. However, there were only a few localized trigger tools that had been established to detect pediatric adverse drug e...

journal_title：BMC pediatrics

authors： Liu Y,Yan J,Xie Y,Bian Y

更新日期：2020-09-29 00:00:00

abstract：BACKGROUND:Haemoptysis is an uncommon presenting symptom in children and is usually caused by acute lower respiratory tract infection or foreign body aspiration. We report a rare case of right unilateral pulmonary vein atresia (PVA) as the underlying aetiology of recurrent haemoptysis in a child. CASE PRESENTATION:A 4...

journal_title：BMC pediatrics

authors： Wong MNL,Tang IP,Chor YK,Lau KS,John AR,Hii KC,Lee OPY,Lim WK,Tan HPK

更新日期：2020-09-24 00:00:00

abstract：BACKGROUND:Type 1 diabetes (T1D) is caused by immune-mediated destruction of the β-cells. After initiation of insulin therapy many patients experience a period of improved residual β-cell function leading to partial disease remission. Cytokines are important immune-modulatory molecules and contribute to β-cell damage i...

journal_title：BMC pediatrics

authors： Overgaard AJ,Madsen JOB,Pociot F,Johannesen J,Størling J

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND:In order for infants and toddlers to meet recommended movement guidelines, their caregivers need to encourage play daily. This study used a qualitative approach to understand how mothers perceive and promote play and physical activity during the first 2 years of life. METHODS:Mothers with children between 0...

journal_title：BMC pediatrics

authors： Prioreschi A,Wrottesley SV,Slemming W,Cohen E,Norris SA

更新日期：2020-09-09 00:00:00

abstract：BACKGROUND:The COVID-19 pandemic has disrupted healthcare systems worldwide. In addition to the direct impact of the virus on patient morbidity and mortality, the effect of lockdown strategies on health and healthcare utilization have become apparent. Little is known on the effect of the pandemic on pediatric and adole...

journal_title：BMC pediatrics

authors： Dopfer C,Wetzke M,Zychlinsky Scharff A,Mueller F,Dressler F,Baumann U,Sasse M,Hansen G,Jablonka A,Happle C

更新日期：2020-09-07 00:00:00

abstract：BACKGROUND:In preterm infants with Respiratory Distress Syndrome (RDS), Less Invasive Surfactant Administration (LISA) has been established to reduce the need of mechanical ventilation and might improve survival rates without bronchopulmonary dysplasia. The aim of this study was to investigate whether NICU care has cha...

journal_title：BMC pediatrics

authors： Bugter IAL,Janssen LCE,Dieleman J,Kramer BW,Andriessen P,Niemarkt HJ

更新日期：2020-09-03 00:00:00

abstract：BACKGROUND:To explore the relationship between the pathological changes of the colon, terminal ileum, lung, liver and kidney, and the changes of Bax, PCNA and PAF in a rat model of NEC. METHODS:One hundred and forty neonatal SD rats were randomly divided into NEC group and control group (70 in each group). NEC group w...

journal_title：BMC pediatrics

authors： Wang FS,Yu ML,Li WZ,Hong K,Xu CB,Wang GH

更新日期：2020-09-02 00:00:00

abstract：BACKGROUND:The Internet may serve as a suitable environment for discriminated adolescents as they may consider the online space as the place where they have possibility to build social ties they are missing in their offline life or manage their self-presentation. Therefore, our aim was to explore the association betwee...

journal_title：BMC pediatrics

authors： Bitto Urbanova L,Holubcikova J,Madarasova Geckova A,van Dijk JP,Reijneveld SA

更新日期：2020-08-25 00:00:00

abstract：BACKGROUND:Melnick-Needles syndrome (MNS) is an extremely rare osteochondrodysplasia caused by a mutation of FLNA, the gene encoding filamin A. MNS is inherited in an X-linked dominant manner. In this study, we describe three members of the same family with MNS, who exhibited different phenotypic severity despite havin...

journal_title：BMC pediatrics

authors： Oh CH,Lee CH,Kim SY,Lee SY,Jun HH,Lee S

更新日期：2020-08-19 00:00:00

abstract：BACKGROUND:Non-Hispanic black (NHB) infants are twice as likely as non-Hispanic white infants to experience rapid weight gain in the first 6 months, yet few trials have targeted this population. The current study tests the efficacy of "Mothers & Others," a home-based intervention for NHB women and their study partners ...

journal_title：BMC pediatrics

authors： Wasser HM,Thompson AL,Suchindran CM,Goldman BD,Hodges EA,Heinig MJ,Bentley ME

更新日期：2020-08-18 00:00:00

abstract：BACKGROUND:At present, there are few studies on the economic burden and medical treatment of children with asthma in China. Thus this study aimed to investigate the economic burden of medical treatment of children with asthma in China. METHOD:The 2015 China Medical Insurance Research Association (CHIRA) database was s...

journal_title：BMC pediatrics

authors： Wu P,Xu B,Shen A,He Z,Zhang CJP,Ming WK,Shen K

更新日期：2020-08-18 00:00:00

abstract：BACKGROUND:To investigate the prevalence and patterns of breastfeeding at discharge and in the first six months of life in a high-risk fetal, neonatal and child referral center. METHODS:Prospective, longitudinal study that included the following three steps: hospital admission, first visit after hospital discharge and...

journal_title：BMC pediatrics

authors： Silva MDB,Carvalhaes de Oliveira RV,Braga JU,de Almeida JAG,Melo ECP

更新日期：2020-08-07 00:00:00

abstract：BACKGROUND:The human foot is shaped throughout all life in a way that is individual for every human being. Footwear fitting in the process of foot development is the issue covered by a limited range of empirical studies. This prompted the authors to undertake this subject of the study aimed at the influence of fitting ...

journal_title：BMC pediatrics

authors： Puszczalowska-Lizis E,Zarzyczna P,Mikulakova W,Migala M,Jandzis S

更新日期：2020-07-20 00:00:00

abstract：BACKGROUND:Severe acute malnutrition affects around 17 million under-five children in the world, of which the highest burden is accounted by Sub-Saharan Africa where Ethiopia is found. Though there are few individual, inconsistent and inconclusive studies, there is no nationally representative study on treatment outcom...

journal_title：BMC pediatrics

authors： Bitew ZW,Alemu A,Worku T

更新日期：2020-07-07 00:00:00

abstract：BACKGROUND:13q33-q34 microdeletions are rare chromosomal aberrations associated with a high risk of developmental disability, facial dysmorphism, cardiac defects and other malformation of organs. It is necessary to collect and report evidence of this rare chromosome mutation to improve the prognosis of this rare diseas...

journal_title：BMC pediatrics

authors： He X,Shen H,Fu H,Feng C,Liu Z,Jin Y,Mao J

更新日期：2020-07-02 00:00:00

abstract：BACKGROUND:With the importance of early childhood development more recognized by the international society, low-cost and cross-culturally comparable measures of early childhood development is in great demand, both in China and worldwide. In this study, we aim to test the psychometrics of the Chinese version of The Earl...

journal_title：BMC pediatrics

authors： Zhao J,Brinkman SA,Zhang Y,Song Y,Lu C,Young ME,Zhang Y,Ip P,Shan W,Jiang F

更新日期：2020-06-30 00:00:00

abstract：BACKGROUND:Continuous monitoring of SpO2 in the neonatal ICU is the standard of care. Changes in SpO2 exposure have been shown to markedly impact outcome, but limiting extreme episodes is an arduous task. Much more complicated than setting alarm policy, it is fraught with balancing alarm fatigue and compliance. Informa...

journal_title：BMC pediatrics

authors： Bachman TE,Iyer NP,Newth CJL,Ross PA,Khemani RG

更新日期：2020-06-27 00:00:00

abstract：BACKGROUND:Sleep-disordered breathing (SDB) is a common syndrome in children, related to their immune responses, cardiovascular function, and neurocognitive function. This study aimed to determine the prevalence of SDB among children in Wuxi, China, and to evaluate the protective and risk factors of SDB in children. M...

journal_title：BMC pediatrics

authors： Guo Y,Pan Z,Gao F,Wang Q,Pan S,Xu S,Hui Y,Li L,Qian J

更新日期：2020-06-26 00:00:00

abstract：BACKGROUND:Currently in the United States, childhood injuries are the leading cause of mortality and morbidity, resulting in an estimated 9.2 million emergency department visits and $17 billion annually in medical costs. For preschoolers, it is also the leading cause of disability. METHODS:We use linked administrative...

journal_title：BMC pediatrics

authors： Heflin CM,Arteaga I,Ndashimye JF,Rabbitt MP

更新日期：2020-06-17 00:00:00

abstract：BACKGROUND:Several environmental factors favour the occurrence of acute respiratory disease, which is the main reason for paediatric consultations in our country (Colombia). Tobacco smoke is considered a significant environmental pollutant with a great impact on health. The objective of this study is to estimate the pr...

journal_title：BMC pediatrics

authors： Tovar MF,Ortiz W,Valderrama MA,Rodríguez F,Gamboa O,Maldonado MJ,Agudelo SI

更新日期：2020-06-16 00:00:00