听力与言语-语言病理学

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  • Nutritional Requirements for Sustaining Health and Performance During Exposure to Extreme Environments.

    abstract::Dietary guidelines are formulated to meet minimum nutrient requirements, which prevent deficiencies and maintain health, growth, development, and function. These guidelines can be inadequate and contribute to disrupted homeostasis, lean body mass loss, and deteriorated performance in individuals who are working long, ...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章

    doi:10.1146/annurev-nutr-011720-122637

    authors: Pasiakos SM

    更新日期:2020-09-23 00:00:00

  • Nutrition Regulates Innate Immunity in Health and Disease.

    abstract::Nutrient content and nutrient timing are considered key regulators of human health and a variety of diseases and involve complex interactions with the mucosal immune system. In particular, the innate immune system is emerging as an important signaling hub that modulates the response to nutritional signals, in part via...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章

    doi:10.1146/annurev-nutr-120919-094440

    authors: Nobs SP,Zmora N,Elinav E

    更新日期:2020-09-23 00:00:00

  • FADS1 and FADS2 Polymorphisms Modulate Fatty Acid Metabolism and Dietary Impact on Health.

    abstract::Variants in the FADS gene cluster modify the activity of polyunsaturated fatty acid (PUFA) desaturation and the lipid composition in human blood and tissue. FADS variants have been associated with plasma lipid concentrations, risk of cardiovascular diseases, overweight, eczema, pregnancy outcomes, and cognitive functi...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-082018-124250

    authors: Koletzko B,Reischl E,Tanjung C,Gonzalez-Casanova I,Ramakrishnan U,Meldrum S,Simmer K,Heinrich J,Demmelmair H

    更新日期:2019-08-21 00:00:00

  • Consumption of Sugars, Sugary Foods, and Sugary Beverages in Relation to Cancer Risk: A Systematic Review of Longitudinal Studies.

    abstract::High sugar intake may increase cancer risk by promoting insulin-glucose dysregulation, oxidative stress, inflammation, and body adiposity, but epidemiologic evidence is unclear. Associations between dietary sugars and lifestyle-related cancer risk from longitudinal studies were evaluated. We systematically searched Pu...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章

    doi:10.1146/annurev-nutr-082117-051805

    authors: Makarem N,Bandera EV,Nicholson JM,Parekh N

    更新日期:2018-08-21 00:00:00

  • Single-Subject Studies in Translational Nutrition Research.

    abstract::There is a great deal of interest in personalized, individualized, or precision interventions for disease and health-risk mitigation. This is as true of nutrition-based intervention and prevention strategies as it is for pharmacotherapies and pharmaceutical-oriented prevention strategies. Essentially, technological br...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071816-064717

    authors: Schork NJ,Goetz LH

    更新日期:2017-08-21 00:00:00

  • Genetic Risk Factors for Folate-Responsive Neural Tube Defects.

    abstract::Neural tube defects (NTDs) are the most severe congenital malformations of the central nervous system. The etiology is complex, with both genetic and environmental factors having important contributions. Researchers have known for the past two decades that maternal periconceptional use of the B vitamin folic acid can ...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071714-034235

    authors: Molloy AM,Pangilinan F,Brody LC

    更新日期:2017-08-21 00:00:00

  • Nutrient-Gene Interaction in Colon Cancer, from the Membrane to Cellular Physiology.

    abstract::The International Agency for Research on Cancer recently released an assessment classifying red and processed meat as "carcinogenic to humans" on the basis of the positive association between increased consumption and risk for colorectal cancer. Diet, however, can also decrease the risk for colorectal cancer and be us...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071715-051039

    authors: Hou TY,Davidson LA,Kim E,Fan YY,Fuentes NR,Triff K,Chapkin RS

    更新日期:2016-07-17 00:00:00

  • Variation in the Ability to Taste Bitter Thiourea Compounds: Implications for Food Acceptance, Dietary Intake, and Obesity Risk in Children.

    abstract::The ability to taste bitter thiourea compounds, such as phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP), is inherited. Polymorphisms in the bitter-taste receptor TAS2R38 explain the majority of phenotypic variation in the PROP phenotype. It has been hypothesized that the PROP phenotype is a marker for percep...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071715-050916

    authors: Keller KL,Adise S

    更新日期:2016-07-17 00:00:00

  • The Neurobiology of "Food Addiction" and Its Implications for Obesity Treatment and Policy.

    abstract::There is a growing view that certain foods, particularly those high in refined sugars and fats, are addictive and that some forms of obesity can usefully be treated as a food addiction. This perspective is supported by a growing body of neuroscience research demonstrating that the chronic consumption of energy-dense f...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071715-050909

    authors: Carter A,Hendrikse J,Lee N,Yücel M,Verdejo-Garcia A,Andrews ZB,Hall W

    更新日期:2016-07-17 00:00:00

  • Regulation of the Epigenome by Vitamin C.

    abstract::Emerging evidence suggests that ascorbate, the dominant form of vitamin C under physiological pH conditions, influences activity of the genome via regulating epigenomic processes. Ascorbate serves as a cofactor for Ten-eleven translocation (TET) dioxygenases that catalyze the oxidation of 5-methylcytosine (5mC) into 5...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071714-034228

    authors: Young JI,Züchner S,Wang G

    更新日期:2015-01-01 00:00:00

  • Saturated Fats Versus Polyunsaturated Fats Versus Carbohydrates for Cardiovascular Disease Prevention and Treatment.

    abstract::The effects of saturated fatty acids (SFAs) on cardiovascular disease (CVD) risk are modulated by the nutrients that replace them and their food matrices. Replacement of SFAs with polyunsaturated fatty acids has been associated with reduced CVD risk, although there is heterogeneity in both fatty acid categories. In co...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071714-034449

    authors: Siri-Tarino PW,Chiu S,Bergeron N,Krauss RM

    更新日期:2015-01-01 00:00:00

  • Hypoxia and adipocyte physiology: implications for adipose tissue dysfunction in obesity.

    abstract::Hypoxia develops in white adipose tissue in obese mice, resulting in changes in adipocyte function that may underpin the dysregulation that leads to obesity-associated disorders. Whether hypoxia occurs in adipose tissue in human obesity is unclear, with recent studies contradicting earlier reports that this was the ca...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071812-161156

    authors: Trayhurn P

    更新日期:2014-01-01 00:00:00

  • Vitamin D as a neurosteroid affecting the developing and adult brain.

    abstract::Vitamin D deficiency is prevalent throughout the world, and growing evidence supports a requirement for optimal vitamin D levels for the healthy developing and adult brain. Vitamin D has important roles in proliferation and differentiation, calcium signaling within the brain, and neurotrophic and neuroprotective actio...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071813-105557

    authors: Groves NJ,McGrath JJ,Burne TH

    更新日期:2014-01-01 00:00:00

  • Molecular mediators governing iron-copper interactions.

    abstract::Given their similar physiochemical properties, it is a logical postulate that iron and copper metabolism are intertwined. Indeed, iron-copper interactions were first documented over a century ago, but the homeostatic effects of one on the other has not been elucidated at a molecular level to date. Recent experimental ...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071812-161215

    authors: Gulec S,Collins JF

    更新日期:2014-01-01 00:00:00

  • Quantifying diet for nutrigenomic studies.

    abstract::The field of nutrigenomics shows tremendous promise for improved understanding of the effects of dietary intake on health. The knowledge that metabolic pathways may be altered in individuals with genetic variants in the presence of certain dietary exposures offers great potential for personalized nutrition advice. How...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-072610-145203

    authors: Tucker KL,Smith CE,Lai CQ,Ordovas JM

    更新日期:2013-01-01 00:00:00

  • Selenoproteins and cancer prevention.

    abstract::The discovery of multiple selenoproteins has raised tantalizing questions about their role in maintaining normal cellular function. Unfortunately, many of these remain inadequately investigated. While they have a role in maintaining redox balance, other functions are becoming increasingly recognized. As the roles of t...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-071811-150740

    authors: Davis CD,Tsuji PA,Milner JA

    更新日期:2012-08-21 00:00:00

  • What are the risks and benefits to increasing dietary bone minerals and vitamin D intake in infants and small children?

    abstract::Bone minerals and vitamin D are crucial for infants and small children. Human milk has little vitamin D, and supplemental vitamin D must be given to all infants either via drops or as contained in infant formula or foods. The calcium and phosphorus in human milk are adequate for infants in the first six months of life...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-072610-145216

    authors: Abrams SA

    更新日期:2011-08-21 00:00:00

  • Micronutrients, birth weight, and survival.

    abstract::Maternal micronutrient requirements during pregnancy increase to meet the physiologic changes in gestation and fetal demands for growth and development. Maternal micronutrient deficiencies are high and coexist in many settings, likely influencing birth and newborn outcomes. The only recommendation for pregnancy curren...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.012809.104813

    authors: Christian P

    更新日期:2010-08-21 00:00:00

  • Compartmentalization of Mammalian folate-mediated one-carbon metabolism.

    abstract::The recognition that mitochondria participate in folate-mediated one-carbon metabolism grew out of pioneering work beginning in the 1950s from the laboratories of D.M. Greenberg, C.G. Mackenzie, and G. Kikuchi. These studies revealed mitochondria as the site of oxidation of one-carbon donors such as serine, glycine, s...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.012809.104810

    authors: Tibbetts AS,Appling DR

    更新日期:2010-08-21 00:00:00

  • Is there a fatty acid taste?

    abstract::Taste is a chemical sense that aids in the detection of nutrients and guides food choice. A limited number of primary qualities comprise taste. Accumulating evidence has raised a question about whether fat should be among them. Most evidence indicates triacylglycerol is not an effective taste stimulus, though it clear...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-080508-141108

    authors: Mattes RD

    更新日期:2009-01-01 00:00:00

  • Dietary protein, weight loss, and weight maintenance.

    abstract::The role of dietary protein in weight loss and weight maintenance encompasses influences on crucial targets for body weight regulation, namely satiety, thermogenesis, energy efficiency, and body composition. Protein-induced satiety may be mainly due to oxidation of amino acids fed in excess, especially in diets with "...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev-nutr-080508-141056

    authors: Westerterp-Plantenga MS,Nieuwenhuizen A,Tomé D,Soenen S,Westerterp KR

    更新日期:2009-01-01 00:00:00

  • Protein and amino acid metabolism in the human newborn.

    abstract::Birth and adaptation to extrauterine life involve major shifts in the protein and energy metabolism of the human newborn. These include a shift from a state of continuous supply of nutrients including amino acids from the mother to cyclic periodic oral intake, a change in the redox state of organs, thermogenesis, and ...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.28.061807.155333

    authors: Kalhan SC,Bier DM

    更新日期:2008-01-01 00:00:00

  • The emerging functions and mechanisms of mammalian fatty acid-binding proteins.

    abstract::Fatty acid-binding proteins (FABPs) are abundant intracellular proteins that bind long-chain fatty acids with high affinity. Nine separate mammalian FABPs have been identified, and their tertiary structures are highly conserved. The FABPs have unique tissue-specific distributions that have long suggested functional di...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.27.061406.093710

    authors: Storch J,Corsico B

    更新日期:2008-01-01 00:00:00

  • Association of maternal obesity before conception with poor lactation performance.

    abstract::The objective of this review is to evaluate the evidence for a link between maternal obesity and poor lactation performance. In nonhuman species, excess maternal fatness is deleterious for lactation and also for maternal health and survival. These effects occur during pregnancy and as milk production is beginning. The...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.27.061406.093738

    authors: Rasmussen KM

    更新日期:2007-01-01 00:00:00

  • Conserved and tissue-specific genic and physiologic responses to caloric restriction and altered IGFI signaling in mitotic and postmitotic tissues.

    abstract::Caloric restriction (CR), the consumption of fewer calories without malnutrition, and reduced insulin and/or IGFI receptor signaling delay many age-related physiological changes and extend the lifespan of many model organisms. Here, we present and review microarray and biochemical studies indicating that the potent an...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.27.061406.093743

    authors: Spindler SR,Dhahbi JM

    更新日期:2007-01-01 00:00:00

  • Role of dietary proteins and amino acids in the pathogenesis of insulin resistance.

    abstract::Dietary proteins and amino acids are important modulators of glucose metabolism and insulin sensitivity. Although high intake of dietary proteins has positive effects on energy homeostasis by inducing satiety and possibly increasing energy expenditure, it has detrimental effects on glucose homeostasis by promoting ins...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.25.050304.092545

    authors: Tremblay F,Lavigne C,Jacques H,Marette A

    更新日期:2007-01-01 00:00:00

  • Regulation of lipolysis in adipocytes.

    abstract::Lipolysis of white adipose tissue triacylglycerol stores results in the liberation of glycerol and nonesterified fatty acids that are released into the vasculature for use by other organs as energy substrates. In response to changes in nutritional state, lipolysis rates are precisely regulated through hormonal and bio...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.27.061406.093734

    authors: Duncan RE,Ahmadian M,Jaworski K,Sarkadi-Nagy E,Sul HS

    更新日期:2007-01-01 00:00:00

  • Variations on a gene: rare and common variants in ABCA1 and their impact on HDL cholesterol levels and atherosclerosis.

    abstract::Cholesterol and its metabolites play a variety of essential roles in living systems. Virtually all animal cells require cholesterol, which they acquire through synthesis or uptake, but only the liver can degrade cholesterol. The ABCA1 gene product regulates the rate-controlling step in the removal of cellular choleste...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.26.061505.111214

    authors: Brunham LR,Singaraja RR,Hayden MR

    更新日期:2006-01-01 00:00:00

  • Food allergies: prevalence, molecular characterization, and treatment/prevention strategies.

    abstract::A significant proportion of the population is either affected by or concerned about food allergy. Our knowledge about food allergens and how they stimulate the immune system has increased dramatically over the past decade. However, reasons for the increased prevalence of food allergy are not clear. The diagnosis of fo...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.26.061505.111211

    authors: Lee LA,Burks AW

    更新日期:2006-01-01 00:00:00

  • Fatty acids as modulators of the immune response.

    abstract::Research describing fatty acids as modulators of inflammation and immune responses abounds. Many of these studies have focused on one particular group of fatty acids, omega-3. The data from animal studies have shown that these fatty acids can have powerful anti-inflammatory and immunomodulatory activities in a wide ar...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.25.050304.092610

    authors: Fritsche K

    更新日期:2006-01-01 00:00:00

  • Regulation of iron metabolism by hepcidin.

    abstract::Hepcidin, a peptide hormone made in the liver, is the principal regulator of systemic iron homeostasis. Hepcidin controls plasma iron concentration and tissue distribution of iron by inhibiting intestinal iron absorption, iron recycling by macrophages, and iron mobilization from hepatic stores. Hepcidin acts by inhibi...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.26.061505.111303

    authors: Nemeth E,Ganz T

    更新日期:2006-01-01 00:00:00

  • Mechanisms of digestion and absorption of dietary vitamin A.

    abstract::Mechanisms involved in the digestion and absorption of dietary vitamin A require the participation of several proteins. Dietary retinyl esters are hydrolyzed in the intestine by the pancreatic enzyme, pancreatic triglyceride lipase, and intestinal brush border enzyme, phospholipase B. Unesterified retinol taken up by ...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.25.050304.092614

    authors: Harrison EH

    更新日期:2005-01-01 00:00:00

  • Polyunsaturated fatty acid regulation of genes of lipid metabolism.

    abstract::Apart from being an important macronutrient, dietary fat has recently gained much prominence for its role in regulating gene expression. Polyunsaturated fatty acids (PUFAs) affect gene expression through various mechanisms including, but not limited to, changes in membrane composition, intracellular calcium levels, an...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.25.051804.101917

    authors: Sampath H,Ntambi JM

    更新日期:2005-01-01 00:00:00

  • On becoming a nutritional biochemist.

    abstract::Much of the science underlying nutrition has come from biochemical studies. This certainly is true in our understanding of the metabolism and function of such micronutrient cofactors as vitamins and metal ions. My own interest stems from an early desire to understand the molecular events in an organism and ultimately ...

    journal_title:Annual review of nutrition

    pub_type: 传,历史文章,杂志文章

    doi:10.1146/annurev.nutr.24.120203.113511

    authors: McCormick DB

    更新日期:2004-01-01 00:00:00

  • Nutrition and cancer prevention: a multidisciplinary perspective on human trials.

    abstract::More than one million Americans were expected to be diagnosed with cancer in 2003 (7a). Compelling experimental, epidemiological, and clinical evidence indicates that many cancers are preventable, especially because diet and nutrition are key factors in the modulation of cancer risk. The road to nutritional interventi...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.24.012003.132315

    authors: Forman MR,Hursting SD,Umar A,Barrett JC

    更新日期:2004-01-01 00:00:00

  • Bioactive compounds in nutrition and health-research methodologies for establishing biological function: the antioxidant and anti-inflammatory effects of flavonoids on atherosclerosis.

    abstract::Identifying bioactive compounds and establishing their health effects are active areas of scientific inquiry. There are exciting prospects that select bioactive compounds will reduce the risk of many diseases, including chronic diseases such as cardiovascular disease. Recent findings have established that cardiovascul...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.23.011702.073237

    authors: Kris-Etherton PM,Lefevre M,Beecher GR,Gross MD,Keen CL,Etherton TD

    更新日期:2004-01-01 00:00:00

  • Different approaches to define individual amino acid requirements.

    abstract::A full review of the strengths and limitations of the various methods used to define amino acid requirements is provided. The focus is on the recent development of carbon oxidation techniques such as indicator amino acid oxidation and 24-h amino acid balance to determine dietary indispensable (essential) amino acid ne...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.23.011702.073247

    authors: Pencharz PB,Ball RO

    更新日期:2003-01-01 00:00:00

  • Rough and rocky road to the retinoid revolution.

    abstract::Some of us who were born in the middle of Europe between World Wars I and II had to face quite a few unusual challenges that we all met in different ways. I was born and raised in Prague, Czechoslovakia, a country at the time of my birth that was governed by a Western style of democracy, which was later destroyed by t...

    journal_title:Annual review of nutrition

    pub_type: 传,历史文章,杂志文章

    doi:10.1146/annurev.nutr.23.011702.073155

    authors: Chytil F

    更新日期:2003-01-01 00:00:00

  • Iron status and neural functioning.

    abstract::Iron deficiency in early life is associated with delayed development as assessed by a number of clinical trials using similar global scales of development; this poor development during infancy persists in most cases after iron therapy has corrected iron status. If iron deficiency occurs in preschool and older children...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.23.020102.075739

    authors: Beard JL,Connor JR

    更新日期:2003-01-01 00:00:00

  • Nutritional impact of pre- and probiotics as protective gastrointestinal organisms.

    abstract::The health benefits of pre- and probiotics have been the subject of increased research interests. These food supplements have been demonstrated to alter the pre-existing intestinal flora so as to provide an advantage to the host. This review focuses on the scientific evidence both for and against their role in promoti...

    journal_title:Annual review of nutrition

    pub_type: 杂志文章,评审

    doi:10.1146/annurev.nutr.22.110901.145412

    authors: Teitelbaum JE,Walker WA

    更新日期:2002-01-01 00:00:00

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