Regulation of iron metabolism by hepcidin.

abstract：:A significant proportion of the population is either affected by or concerned about food allergy. Our knowledge about food allergens and how they stimulate the immune system has increased dramatically over the past decade. However, reasons for the increased prevalence of food allergy are not clear. The diagnosis of fo...

journal_title：Annual review of nutrition

authors： Lee LA,Burks AW

更新日期：2006-01-01 00:00:00

abstract：:Taste is a chemical sense that aids in the detection of nutrients and guides food choice. A limited number of primary qualities comprise taste. Accumulating evidence has raised a question about whether fat should be among them. Most evidence indicates triacylglycerol is not an effective taste stimulus, though it clear...

journal_title：Annual review of nutrition

authors： Mattes RD

更新日期：2009-01-01 00:00:00

abstract：:The recognition that mitochondria participate in folate-mediated one-carbon metabolism grew out of pioneering work beginning in the 1950s from the laboratories of D.M. Greenberg, C.G. Mackenzie, and G. Kikuchi. These studies revealed mitochondria as the site of oxidation of one-carbon donors such as serine, glycine, s...

journal_title：Annual review of nutrition

authors： Tibbetts AS,Appling DR

更新日期：2010-08-21 00:00:00

abstract：:It appears that specific functions may be assigned to some of the cellular folate binding proteins with some degree of certainty. Those that are membrane bound or derived from membranes probably have a role in transport of folate molecules into the cell. This is in spite of the fact that the localization of this prote...

journal_title：Annual review of nutrition

authors： Wagner C

更新日期：1982-01-01 00:00:00

abstract：:Some of us who were born in the middle of Europe between World Wars I and II had to face quite a few unusual challenges that we all met in different ways. I was born and raised in Prague, Czechoslovakia, a country at the time of my birth that was governed by a Western style of democracy, which was later destroyed by t...

journal_title：Annual review of nutrition

authors： Chytil F

更新日期：2003-01-01 00:00:00

abstract：:Investigations into regulating metabolic pathways with stable isotopes have, over the past decade, undergone major development with the use of nuclear magnetic resonance and mass spectrometry in studying labeling patterns of newly synthesized biomolecules. In this review, we concentrate on investigations of mass isoto...

journal_title：Annual review of nutrition

authors： Brunengraber H,Kelleher JK,Des Rosiers C

更新日期：1997-01-01 00:00:00

abstract：:In summary, nutritionally directed alterations in thyroid hormone metabolism appear to be adaptive and to serve important protective roles in the overall economy of the body. These adjustments to nutrition are found at practically every level of thyroid regulation, beginning in the CNS and ending with the final action...

journal_title：Annual review of nutrition

authors： Danforth E Jr,Burger AG

更新日期：1989-01-01 00:00:00

abstract：:It is clear that many diseases are known to involve defects in vitamin B6 metabolism, but that even more await definitive studies. Furthermore, some functions of vitamin B6, such as its role in glucocorticoid action (21), have been discovered so recently that the medical implications have not yet been fully explored. ...

journal_title：Annual review of nutrition

authors： Merrill AH Jr,Henderson JM

更新日期：1987-01-01 00:00:00

abstract：:Oxidative stress is implicated in the pathogenesis of several viral infections, including hepatitis, influenza, and AIDS. Dietary oxidative stress due to either selenium or vitamin E deficiency increases cardiac damage in mice infected with a myocarditic strain of coxsackievirus B3. Such dietary oxidative stress also ...

journal_title：Annual review of nutrition

authors： Beck MA,Levander OA

更新日期：1998-01-01 00:00:00

abstract：:Birth and adaptation to extrauterine life involve major shifts in the protein and energy metabolism of the human newborn. These include a shift from a state of continuous supply of nutrients including amino acids from the mother to cyclic periodic oral intake, a change in the redox state of organs, thermogenesis, and ...

journal_title：Annual review of nutrition

authors： Kalhan SC,Bier DM

更新日期：2008-01-01 00:00:00

abstract：:Some coffee brewing techniques raise the serum concentration of total and low-density-lipoprotein cholesterol in humans, whereas others do not. The responsible factors are the diterpene lipids cafestol and kahweol, which make up about 1% (wt:wt) of coffee beans. Diterpenes are extracted by hot water but are retained b...

journal_title：Annual review of nutrition

authors： Urgert R,Katan MB

更新日期：1997-01-01 00:00:00

abstract：:Iron deficiency in early life is associated with delayed development as assessed by a number of clinical trials using similar global scales of development; this poor development during infancy persists in most cases after iron therapy has corrected iron status. If iron deficiency occurs in preschool and older children...

journal_title：Annual review of nutrition

authors： Beard JL,Connor JR

更新日期：2003-01-01 00:00:00

abstract：:Thirty years ago, it was suggested that maternal intake of certain vitamins during pregnancy affected the incidence of serious fetal malformations. Subsequent research has revealed that folate (folic acid), a B vitamin, plays a crucial role in the development of the central nervous system during the early weeks of ges...

journal_title：Annual review of nutrition

authors： Butterworth CE Jr,Bendich A

更新日期：1996-01-01 00:00:00

abstract：:Hypoxia develops in white adipose tissue in obese mice, resulting in changes in adipocyte function that may underpin the dysregulation that leads to obesity-associated disorders. Whether hypoxia occurs in adipose tissue in human obesity is unclear, with recent studies contradicting earlier reports that this was the ca...

journal_title：Annual review of nutrition

authors： Trayhurn P

更新日期：2014-01-01 00:00:00

abstract：:The discovery of multiple selenoproteins has raised tantalizing questions about their role in maintaining normal cellular function. Unfortunately, many of these remain inadequately investigated. While they have a role in maintaining redox balance, other functions are becoming increasingly recognized. As the roles of t...

journal_title：Annual review of nutrition

authors： Davis CD,Tsuji PA,Milner JA

更新日期：2012-08-21 00:00:00

abstract：:Trans fatty acids raise plasma low-density lipoprotein (LDL) cholesterol levels in volunteers when exchanged for cis unsaturated fatty acids in the diet. In addition, trans fatty acids may lower high-density lipoprotein (HDL) cholesterol levels and raise triglyceride and lipoprotein(a) levels in plasma. Trans and cis ...

journal_title：Annual review of nutrition

authors： Katan MB,Zock PL,Mensink RP

更新日期：1995-01-01 00:00:00

abstract：:Emerging evidence suggests that ascorbate, the dominant form of vitamin C under physiological pH conditions, influences activity of the genome via regulating epigenomic processes. Ascorbate serves as a cofactor for Ten-eleven translocation (TET) dioxygenases that catalyze the oxidation of 5-methylcytosine (5mC) into 5...

journal_title：Annual review of nutrition

authors： Young JI,Züchner S,Wang G

更新日期：2015-01-01 00:00:00

abstract：:Long-chain fatty acids are involved in all aspects of cellular structure and function. For controlling amounts of fatty acids, cells are endowed with two acetyl-coenzyme A carboxylase (ACC) systems. ACC-alpha is the rate-limiting enzyme in the biogenesis of long-chain fatty acids, and ACC-beta is believed to control m...

journal_title：Annual review of nutrition

authors： Kim KH

更新日期：1997-01-01 00:00:00

abstract：:There are many tumors that have paraneoplastic syndromes. Furthermore, location of certain tumors can result in very specific effects on the host, especially tumors in the hypothalamus, the intestinal tract, or the liver. Finally, tumors of the immune system can have significant distant consequences. However, from dir...

journal_title：Annual review of nutrition

authors： van Eys J

更新日期：1985-01-01 00:00:00

abstract：:Maternal micronutrient requirements during pregnancy increase to meet the physiologic changes in gestation and fetal demands for growth and development. Maternal micronutrient deficiencies are high and coexist in many settings, likely influencing birth and newborn outcomes. The only recommendation for pregnancy curren...

journal_title：Annual review of nutrition

authors： Christian P

更新日期：2010-08-21 00:00:00

abstract：:This review examines the involvement of the gastrointestinal tract in the utilization of nitrogen, the identities of the nitrogenous substances entering and leaving the gut, and the significance of this recycling in the overall nitrogen economy of the body. It is concerned with nonruminant mammals, including man. ...

journal_title：Annual review of nutrition

authors： Fuller MF,Reeds PJ

更新日期：1998-01-01 00:00:00

abstract：:The ability to taste bitter thiourea compounds, such as phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP), is inherited. Polymorphisms in the bitter-taste receptor TAS2R38 explain the majority of phenotypic variation in the PROP phenotype. It has been hypothesized that the PROP phenotype is a marker for percep...

journal_title：Annual review of nutrition

authors： Keller KL,Adise S

更新日期：2016-07-17 00:00:00

abstract：:There is a growing view that certain foods, particularly those high in refined sugars and fats, are addictive and that some forms of obesity can usefully be treated as a food addiction. This perspective is supported by a growing body of neuroscience research demonstrating that the chronic consumption of energy-dense f...

journal_title：Annual review of nutrition

authors： Carter A,Hendrikse J,Lee N,Yücel M,Verdejo-Garcia A,Andrews ZB,Hall W

更新日期：2016-07-17 00:00:00

abstract：:The health benefits of pre- and probiotics have been the subject of increased research interests. These food supplements have been demonstrated to alter the pre-existing intestinal flora so as to provide an advantage to the host. This review focuses on the scientific evidence both for and against their role in promoti...

journal_title：Annual review of nutrition

authors： Teitelbaum JE,Walker WA

更新日期：2002-01-01 00:00:00

abstract：:Recent advances in the knowledge of iron metabolism underscore its complex relationship to overall cell metabolism. One of the key components of the iron uptake and storage pathway is ferritin, a protein that sequesters iron in a nontoxic form. Ferritin synthesis is translationally regulated by iron. Molecules such as...

journal_title：Annual review of nutrition

authors： Mascotti DP,Rup D,Thach RE

更新日期：1995-01-01 00:00:00

abstract：:Epidemiologic and experimental evidence reviewed in this article emphasizes the complex and multifactorial etiology of endemic goiter. The important role of iodine deficiency as an etiologic factor in endemic goiter is firmly established, but there is evidence that other environmental factors can play an equally impor...

journal_title：Annual review of nutrition

authors： Gaitan E

更新日期：1990-01-01 00:00:00

abstract：:Obesity is now recognized as a serious chronic disease, but there is pessimism about how successful treatment can be. A general perception is that almost no one succeeds in long-term maintenance of weight loss. To define long-term weight loss success, we need an accepted definition. We propose defining successful long...

journal_title：Annual review of nutrition

authors： Wing RR,Hill JO

更新日期：2001-01-01 00:00:00

abstract：:How much vitamin E is enough? An established use of supplemental vitamin E in humans is in the prevention and therapy of deficiency symptoms. The cause of vitamin E deficiency, characterized by peripheral neuropathy and ataxia, is usually malabsorption-a result of fat malabsorption or genetic abnormalities in lipoprot...

journal_title：Annual review of nutrition

authors： Traber MG,Sies H

更新日期：1996-01-01 00:00:00

abstract：:The low-density lipoprotein (LDL) receptor (LDL-R) family consists of cell-surface receptors that recognize extracellular ligands and internalize them for degradation by lysosomes. The LDL-R is the prototype of this family, which also contains very-low-density lipoprotein receptors (VLDL-R), apolipoprotein E receptor ...

journal_title：Annual review of nutrition

authors： Hussain MM,Strickland DK,Bakillah A

更新日期：1999-01-01 00:00:00

abstract：:Bone minerals and vitamin D are crucial for infants and small children. Human milk has little vitamin D, and supplemental vitamin D must be given to all infants either via drops or as contained in infant formula or foods. The calcium and phosphorus in human milk are adequate for infants in the first six months of life...

journal_title：Annual review of nutrition

authors： Abrams SA

更新日期：2011-08-21 00:00:00