abstract：BACKGROUND AND PURPOSE:As a leading cause of disability and death in China, stroke as well as its epidemiologic features have gained increasing attention. Prior studies, however, have overgeneralized the north-to-south gradient in China. Whether the differences exist across urban and rural areas remains unexplored. Thi...

journal_title：Journal of stroke

authors： Xia F,Yu X,Li Y,Chen Y,Zhang W,You C,Hu X

更新日期：2020-09-01 00:00:00

abstract：:Spontaneous intracerebral hemorrhage (ICH) is a catastrophic illness causing significant morbidity and mortality. Despite advances in surgical technique addressing primary brain injury caused by ICH, little progress has been made treating the subsequent inflammatory cascade. Pre-clinical studies have made advancements...

journal_title：Journal of stroke

authors： Tschoe C,Bushnell CD,Duncan PW,Alexander-Miller MA,Wolfe SQ

更新日期：2020-01-01 00:00:00

abstract：: ...

journal_title：Journal of stroke

authors： Kim JS

更新日期：2019-09-01 00:00:00

abstract：: ...

journal_title：Journal of stroke

authors： Nam HS,Ha J,Ji D,Kwon I,Lee HS,Han M,Kim YD,Heo JH,Lee SG

更新日期：2019-09-01 00:00:00

abstract：:Endovascular recanalization therapy (ERT) has been a standard of care for patients with acute ischemic stroke due to large artery occlusion (LAO) within 6 hours after onset, since five landmark ERT trials conducted by 2015 demonstrated its clinical benefit. Recently, two randomized clinical trials demonstrated that ER...

journal_title：Journal of stroke

authors： Ko SB,Park HK,Kim BM,Heo JH,Rha JH,Kwon SU,Kim JS,Lee BC,Suh SH,Jung C,Jeong HW,Kang DH,Bae HJ,Yoon BW,Hong KS

更新日期：2019-05-01 00:00:00

abstract：:Trimethylamine N-oxide (TMAO) is produced when trimethylamine, a waste product of gut microbes, is converted via hepatic flavin monooxygenases. As TMAO is a potential causative factor in various cardiovascular diseases (CVDs) considerable research interest has arisen on its use as a biomarker. Higher TMAO levels are a...

journal_title：Journal of stroke

authors： Nam HS

更新日期：2019-05-01 00:00:00

abstract：:Despite the great socioeconomic burden of stroke, there have been few reports of stroke statistics in Korea. In this scenario, the Epidemiologic Research Council of the Korean Stroke Society launched the "Stroke Statistics in Korea" project, aimed at writing a contemporary, comprehensive, and representative report on ...

journal_title：Journal of stroke

authors： Kim JY,Kang K,Kang J,Koo J,Kim DH,Kim BJ,Kim WJ,Kim EG,Kim JG,Kim JM,Kim JT,Kim C,Nah HW,Park KY,Park MS,Park JM,Park JH,Park TH,Park HK,Seo WK,Seo JH,Song TJ,Ahn SH,Oh MS,Oh HG,Yu S,Lee KJ,Lee KB,

更新日期：2019-01-01 00:00:00

abstract：:The optimal treatment strategy for secondary prevention in patients with cryptogenic stroke and patent foramen ovale (PFO) has been a matter of controversy for decades. After three randomized trials failed to show a benefit of closure with an excess of complications in the interventional arm, two large recent trials s...

journal_title：Journal of stroke

authors： Köhrmann M,Schellinger PD,Tsivgoulis G,Steiner T

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The pathogenesis of moyamoya disease (MMD) remains poorly understood, and no reliable molecular biomarkers for MMD have been identified to date. The present study aimed to identify epigenetic biomarkers for use in the diagnosis of MMD. METHODS:We performed integrated analyses of gene expression ...

journal_title：Journal of stroke

authors： Sung HY,Lee JY,Park AK,Moon YJ,Jo I,Park EM,Wang KC,Phi JH,Ahn JH,Kim SK

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To test whether alcohol intake, both observational and estimated by genetic instruments, is associated with risk of ischemic and haemorrhagic stroke. METHODS:We used data from the Copenhagen City Heart Study 1991 to 1994 and 2001 to 2003, and the Copenhagen General Population Study 2003 to 2012 ...

journal_title：Journal of stroke

authors： Christensen AI,Nordestgaard BG,Tolstrup JS

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Thrombolysis >4.5 hours after ischemic stroke onset is unproven. We assessed the feasibility of tenecteplase (TNK) treatment in patients with evidence of an ischemic penumbra 4.5 to 24 hours after onset. METHODS:Acute ischemic stroke patients underwent perfusion computed tomography (CT)/magnetic...

journal_title：Journal of stroke

authors： Kate M,Wannamaker R,Kamble H,Riaz P,Gioia LC,Buck B,Jeerakathil T,Smyth P,Shuaib A,Emery D,Butcher K

更新日期：2018-01-01 00:00:00

abstract：:Heart failure (HF) is one of the major causes of death worldwide. Despite the high incidence of stroke in patients with HF, there has been a controversy as to whether HF itself is a risk factor for stroke. Recently, there is a great deal of evidence that HF itself increases the risk of stroke. In previous studies, the...

journal_title：Journal of stroke

authors： Kim W,Kim EJ

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:To compare the efficacy and safety of antiplatelet agents for the secondary prevention of ischemic stroke based on cytochrome P450 2C19 (CYP2C19) polymorphisms. METHODS:This study was a prospective, multicenter, randomized, parallel-group, open-label, blind genotype trial. First time non-cardiog...

journal_title：Journal of stroke

authors： Han SW,Kim YJ,Ahn SH,Seo WK,Yu S,Oh SH,Nam HS,Choi HY,Yoon SS,Kim SH,Lee JY,Lee JH,Hwang YH,Lee KO,Jung YH,Lee J,Sohn SI,Kim YN,Lee KA,Bushnell CD,Lee KY

更新日期：2017-09-01 00:00:00

abstract：:To date, reperfusion with tissue plasminogen activator (tPA) remains the gold standard treatment for ischemic stroke. However, when tPA is given beyond 4.5 hours of stroke onset, deleterious effects of the drug ensue, especially, hemorrhagic transformation (HT), which causes the most significant morbidity and mortalit...

journal_title：Journal of stroke

authors： Peña ID,Borlongan C,Shen G,Davis W

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Cerebral small vessel disease (SVDs) are related with large artery atherosclerosis. However, the association between aortic atheroma (AA) and cerebral small vessel disease has rarely been reported. This study evaluated the relationship between presence and burden of AAs and those of SVDs in patie...

journal_title：Journal of stroke

authors： Song TJ,Kim YD,Yoo J,Kim J,Chang HJ,Hong GR,Shim CY,Song D,Heo JH,Nam HS

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Early neurologic deterioration (END) occurs in up to one-third of patients with ischemic stroke and is associated with poor outcomes. The purpose of the present study was to determine which stroke etiologies and vascular distributions pose a greater threat of END in stroke patients. METHODS:Usin...

journal_title：Journal of stroke

authors： Siegler JE,Samai A,Semmes E,Martin-Schild S

更新日期：2016-05-01 00:00:00

abstract：:Hypertension is the most important potentially reversible risk factor for stroke in all age groups; high blood pressure (BP) is also associated with increased risk of recurrent stroke in patients who have already had an ischemic or hemorrhagic event. Twenty-four hour ambulatory BP monitoring (ABPM) has become an impor...

journal_title：Journal of stroke

authors： Castilla-Guerra L,Fernandez-Moreno Mdel C

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The benefit of statins in acute stroke remains uncertain. Statins may prevent stroke recurrence during the acute stage of stroke via pleiotropic effects. However, statins may increase the risk of intracerebral hemorrhage. We investigated the effect and safety of rosuvastatin in acute stroke patie...

journal_title：Journal of stroke

authors： Heo JH,Song D,Nam HS,Kim EY,Kim YD,Lee KY,Lee KJ,Yoo J,Kim YN,Lee BC,Yoon BW,Kim JS,EUREKA Investigators.

更新日期：2016-01-01 00:00:00

abstract：:Patent foramen ovale (PFO) is growing in clinical interest because of a renewed focus on embolic stroke of undetermined source (ESUS), the PFO attributable fraction (the 10-point Risk of Paradoxical Embolism score), technical advances in PFO diagnosis, and the emergence of endovascular device closure as a treatment op...

journal_title：Journal of stroke

authors： Bang OY,Lee MJ,Ryoo S,Kim SJ,Kim JW

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Compression of the anterior optic pathway results in visual deficits that can lead to the detection of unruptured aneurysms in the internal carotid artery (ICA). The general types of treatment modalities for aneurysms and visual deficits include surgery and endosaccular coiling. This study retros...

journal_title：Journal of stroke

authors： Park W,Park JC,Han K,Ahn JS,Kwun BD

更新日期：2015-09-01 00:00:00

abstract：:Intravenous thrombolysis is an effective treatment for acute ischaemic stroke. However, vascular recanalization rates remain poor especially in the setting of large artery occlusion. On the other hand, endovascular intra-arterial therapy addresses this issue with superior recanalization rates compared with intravenous...

journal_title：Journal of stroke

authors： Balasubramaian A,Mitchell P,Dowling R,Yan B

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Rapid recanalization might improve clinical outcomes after intraarterial thrombolysis (IAT) for acute ischemic stroke patients with collateral circulation. We determined whether rapid recanalization and collateral circulation affect clinical outcomes after IAT. METHODS:We retrospectively evaluat...

journal_title：Journal of stroke

authors： Jeong HS,Kwon HJ,Song HJ,Koh HS,Kim YS,Lee JH,Shin JE,Lee SH,Kim J

更新日期：2015-01-01 00:00:00

abstract：:Stroke genetics includes several topics of clinical interest, including (1) molecular genetic variations affecting risk of monogenic stroke syndromes; (2) molecular genetic variations affecting risk of common stroke syndromes, sometimes with specific effects on risk of specific main types of stroke or subtypes of isch...

journal_title：Journal of stroke

authors： Lindgren A

更新日期：2014-09-01 00:00:00

abstract：:Stroke is the third leading cause of death and the most common cause of complex disability in Taiwan. The annual age-standardized mortality rate of stroke is steadily decreasing between 2001 and 2012. The average years of potential life lost before age 70 for stroke is 13.8 years, ranked the fifth in the cause of deat...

journal_title：Journal of stroke

authors： Hsieh FI,Chiou HY

更新日期：2014-05-01 00:00:00

abstract：:Proper classification of the causative mechanism of stroke is important for optimizing stroke treatment and assessing prognosis. The primary etiology of stroke differs according to race and ethnicity: emboli originating from the heart or extracranial large arteries are common in Western populations, whereas small-vess...

journal_title：Journal of stroke

authors： Kim BJ,Kim JS

更新日期：2014-01-01 00:00:00

abstract：:CT perfusion (CTP) has been applied increasingly in research of ischemic stroke. However, in clinical practice, it is still a relatively new technology. For neurologists and radiologists, the challenge is to interpret CTP results properly in the context of the clinical presentation. In this article, we will illustrate...

journal_title：Journal of stroke

authors： Lin L,Bivard A,Parsons MW

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Organized inpatient stroke care is one of the most effective therapies for improving patient outcomes. Many stroke centers have been established to meet this need, however, there are limited data on the effectiveness of these organized comprehensive stroke center (CSC) in the real-world setting. ...

journal_title：Journal of stroke

authors： Kim DH,Cha JK,Bae HJ,Park HS,Choi JH,Kang MJ,Kim BG,Huh JT,Kim SB

更新日期：2013-01-01 00:00:00