听力与言语-语言病理学

行为科学

医学伦理学

你正在浏览EPILEPSY RESEARCH期刊下所有文献
  • Semiological differences of focal onset bilateral motor (convulsive) seizure between mesial temporal lobe epilepsy and neocortical epilepsy.

    abstract:OBJECTIVE:We investigated the semiology of focal onset bilateral motor (convulsive) seizure (FBMS) in patients with intractable focal epilepsy who underwent epilepsy surgery to understand its value in localizing the origin of the seizure. METHODS:The study included 20 patients who underwent resective surgery after int...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2021.106553

    authors: Punyawai P,Usui N,Kondo A,Ichikawa N,Tottori T,Terada K,Takahashi Y,Inoue Y

    更新日期:2021-01-07 00:00:00

  • Neural functional connectivity in patients with periventricular nodular heterotopia-mediated epilepsy.

    abstract::Periventricular nodular heterotopia (PNH) is characterized by disabled neural migration and is usually associated with epilepsy. Despite awareness of PNH-related epilepsy, little is known about the brain-level underlying functional neural bases. Thus, we used functional magnetic resonance imaging (MRI) to examine the ...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2021.106548

    authors: Liu W,Yue Q,Tian Y,Gong Q,Zhou D,Wu X

    更新日期:2021-01-05 00:00:00

  • Pregnancy outcomes of refractory epilepsy patients treated with Brain-responsive neurostimulation.

    abstract:OBJECTIVE:To study the pregnancy outcomes, including obstetric complications and fetal outcomes, in pregnant women with epilepsy (WWE) treated with direct brain-responsive neurostimulation (RNS System). METHODS:Retrospective review of obstetric outcomes and fetal outcomes in WWE treated with the RNS System at nine com...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106532

    authors: Li Y,Eliashiv D,LaHue SC,Rao VR,Martini ML,Panov F,Oster JM,Yoshii-Contreras J,Skidmore CT,Kalayjian LA,Millett D,Meador KJ

    更新日期:2021-01-01 00:00:00

  • Time of day is an inaccurate surrogate marker for sleep-wake state in an epilepsy monitoring unit.

    abstract:OBJECTIVE:To assess the correlation between time of day and sleep-wake state prior to seizure onset for seizures recorded in an inpatient epilepsy monitoring unit. METHODS:We prospectively enrolled a consecutive series of patients undergoing inpatient epilepsy monitoring. For each epileptic seizure recorded, continuou...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106524

    authors: Ha KH,Schomer AC,Leonardo J,Quigg M

    更新日期:2021-01-01 00:00:00

  • Self-limited epilepsy with centro-temporal spikes: A study of 46 patients with unusual clinical manifestations.

    abstract:PURPOSE:We retrospectively analyzed the seizure characteristics, EEG pattern, treatment, and outcome in a series of patients with self-limited epilepsy with centrotemporal spikes (SLECTS) who presented with unusual clinical manifestations. METHOD:A retrospective, descriptive, multicenter study was conducted evaluating...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106507

    authors: Galicchio S,Espeche A,Cersosimo R,Chacon S,Gamboni B,Adi J,Fasulo L,Semprino M,Fortini S,Cachia P,Caraballo RH

    更新日期:2021-01-01 00:00:00

  • Reduced H3 histamine receptor binding densities in the upper layers of motor cortex in rats prone to audiogenic convulsive seizures.

    abstract::Fits of audiogenic seizures in rodents are considered as a model for generalized convulsive epilepsies in humans. The laminar distribution of the H3 histamine receptor binding densities was quantified in the motor cortex of two strains of rats with genetically determined generalized epilepsies, namely KM rats with aud...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106543

    authors: Midzyanovskaya IS,Petrenko TE,Birioukova LM,Tuomisto LM

    更新日期:2020-12-25 00:00:00

  • Testing broad-spectrum and isoform-preferring HCN channel blockers for anticonvulsant properties in mice.

    abstract::Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels have been implicated in the pathogenesis of epilepsy and consequently as targets for anticonvulsant drugs. Consistent with this, broad-spectrum block of HCN-mediated current (Ih) reduces seizure susceptibility in a variety of epilepsy models. However, ...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106484

    authors: Kharouf Q,Pinares-Garcia P,Romanelli MN,Reid CA

    更新日期:2020-12-01 00:00:00

  • Shift in electrocorticography electrode locations after surgical implantation in children.

    abstract::Interpreting electrocorticography (ECoG) in the context of neuroimaging requires that multimodal information be integrated accurately. However, the implantation of ECoG electrodes can shift the brain impacting the spatial interpretation of electrode locations in the context of pre-implant imaging. We characterized the...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106410

    authors: Foldes ST,Munter BT,Appavu BL,Kerrigan JF,Adelson PD

    更新日期:2020-11-01 00:00:00

  • Levetiracetam effect on behavioral and electrophysiological parameters in rat model of global brain ischemia.

    abstract::Post-stroke paroxysmal activity is a neurophysiological indicator of epileptogenesis and increase of seizure susceptibility, so treatments with neuroprotective activity and anti-paroxysmal activity can be more beneficial during post-ischemic period. The goal of this study was evaluation of levetiracetam (100 mg/kg, 7 ...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106466

    authors: Litvinova SA,Kutepova IS,Voronina TA,Petrunina АА

    更新日期:2020-11-01 00:00:00

  • Aphasic status epilepticus in a tertiary referral center in Turkey: Clinical features, etiology, and outcome.

    abstract:OBJECTIVE:Aphasic status epilepticus (ASE), although rare, may often remain underdiagnosed. We aimed to report the patients diagnosed with ASE and describe their clinical presentation, etiology, electrophysiological findings, neuroimaging, treatment options, and outcome. METHODS:We retrospectively analyzed a series of...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106479

    authors: Azman F,Tezer FI,Saygi S

    更新日期:2020-11-01 00:00:00

  • Familial mesial temporal lobe epilepsy in Mexico: Inheritance pattern and clinical features.

    abstract:PURPOSE:The objectives of this study were to determine the inheritance pattern by which familial mesial temporal lobe epilepsy (FMTLE) is segregated in Mexican families, and to identify if there was an association between the clinical characteristics and the inheritance pattern. METHOD:We included a total of 25 famili...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106450

    authors: Guzmán-Jiménez DE,Campos JB,Venegas-Vega CA,Sánchez MA,Velasco AL

    更新日期:2020-11-01 00:00:00

  • Quality of life and stigma in Lebanese people with epilepsy taking medication.

    abstract:BACKGROUND:Epilepsy is among the more stigmatising diseases, leading to a negative impact on the quality of life (QoL) of people with epilepsy (PWE). Assessment of the QoL and stigma in PWE reflects the outcome of their disease, and the findings can be used to improve the management of epilepsy. To fill a gap in the li...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106437

    authors: Mroueh L,Boumediene F,Jost J,Ratsimbazafy V,Preux PM,Salameh P,Al-Hajje A

    更新日期:2020-11-01 00:00:00

  • A gut feeling about the ketogenic diet in epilepsy.

    abstract::The ketogenic diet has been used to treat intractable epilepsy for many years, yet the mechanism(s) underlying its effectiveness have not been completely elucidated. However, emerging evidence indicates that the ketogenic diet may correct or otherwise alter a 'dystopic' gut microbiota that exhibits altered fecal micro...

    journal_title:Epilepsy research

    pub_type: 杂志文章,评审

    doi:10.1016/j.eplepsyres.2020.106409

    authors: Pittman QJ

    更新日期:2020-10-01 00:00:00

  • Telomere shortening in patients with drug-resistant epilepsy.

    abstract::Epilepsy affects about 1 % of the world population. Mesial temporal lobe epilepsy (mTLE) presents with seizures initiated in hippocampus and is the most frequent form of epilepsy. About 30 % of individuals with mTLE do not respond to conventional medications maintaining seizures and consequently new lesions on a daily...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106427

    authors: Miranda DM,Rosa DV,Costa BS,Nicolau NF,Magno LAV,de Paula JJ,Romano-Silva MA

    更新日期:2020-10-01 00:00:00

  • LPDs - «Linked to penumbra» discharges or EEG correlate of excitotoxicity: A review based hypothesis.

    abstract::Periodic lateralized epileptiform discharges (PLEDs) or lateralized periodic discharges (LPDs) are a well-known variant of pathological EEG activity. However, the mechanisms underpinning the appearance of this pattern are not completely understood. The heterogeneity of the features derived from LPDs patterns, and the ...

    journal_title:Epilepsy research

    pub_type: 杂志文章,评审

    doi:10.1016/j.eplepsyres.2020.106429

    authors: Chegodaev D,Pavlova NV,Pavlova P,Lvova O

    更新日期:2020-10-01 00:00:00

  • Immediate versus late effects of vigabatrin on spike and wave discharges.

    abstract::Vigabatrin increases GABA concentrations by inhibiting GABA transaminase. In previous studies, it was shown that vigabatrin increases the incidence of Spike and Wave Discharges (SWD) in the WAG/Rij rat model for absence epilepsy. Since following a single dose of vigabatrin GABA concentrations are known to be increased...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106379

    authors: Perescis MFJ,van Luijtelaar G,van Rijn CM

    更新日期:2020-09-01 00:00:00

  • Electro-clinical analysis of epilepsy patients with generalized seizures on adjunctive perampanel treatment.

    abstract::Quantifying epileptiform discharges before and after the initiation of treatment can be useful for evaluating the efficacy of antiepileptic drugs in generalized epilepsy. The aim of this study was to determine if the selective α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor antagonist perampanel ...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106378

    authors: Montoya Gutiérrez FJ,Díaz Román M,Cerveró Albert D

    更新日期:2020-09-01 00:00:00

  • Anticonvulsant Effects of Thalidomide on Pentylenetetrazole-Induced Seizure in Mice: A Role for Opioidergic and Nitrergic Transmissions.

    abstract::Although accumulating evidence indicates that the immunomodulatory medication thalidomide exerts anticonvulsant properties, the mechanisms underlying such effects of thalidomide are still unknown. Our previous preclinical study suggested that nitric oxide (NO) signaling may be involved in the anticonvulsant effects of...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106362

    authors: Pourshadi N,Rahimi N,Ghasemi M,Faghir-Ghanesefat H,Sharifzadeh M,Dehpour AR

    更新日期:2020-08-01 00:00:00

  • Immunotherapy for GRIN2A and GRIN2D-related epileptic encephalopathy.

    abstract:BACKGROUND:GRIN-related developmental-epileptic encephalopathies are associated with a spectrum of neurodevelopmental disorders, including intellectual disability, epilepsy including continuous spike-and-wave during sleep syndrome (CSWS), or epilepsy-aphasia spectrum phenotypes such as in Landau-Kleffner syndrome. Effi...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106325

    authors: Hausman-Kedem M,Menascu S,Greenstein Y,Fattal-Valevski A

    更新日期:2020-07-01 00:00:00

  • The interactions between anticonvulsants and non-vitamin K antagonist oral anticoagulant agents: A systematic review.

    abstract::Use of non-vitamin K antagonist oral anticoagulants (NOACs), including dabigatran etexilate, rivaroxaban, apixaban, edoxaban or betrixaban provides a safe and convenient alternative to the traditional anticoagulation with vitamin K antagonists or heparin derivatives. Many patients receiving long-term seizure prophylax...

    journal_title:Epilepsy research

    pub_type: 杂志文章,评审

    doi:10.1016/j.eplepsyres.2020.106304

    authors: Taha M,Li W,Schmidt CM,Gonzalez-Castellon M,Taraschenko O

    更新日期:2020-05-01 00:00:00

  • Transcriptome analysis of rat dorsal hippocampal CA1 after an early life seizure induced by kainic acid.

    abstract::Seizures that occur during early development are associated with adverse neurodevelopmental outcomes. Causation and mechanisms are currently under investigation. Induction of an early life seizure by kainic acid (KA) in immature rats on post-natal day (P) 7 results in behavioral changes in the adult rat that reflect s...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106283

    authors: O'Leary H,Vanderlinden L,Southard L,Castano A,Saba LM,Benke TA

    更新日期:2020-03-01 00:00:00

  • Electrocorticographic events from long-term ambulatory brain recordings can potentially supplement seizure diaries.

    abstract:PURPOSE:To determine the feasibility of using epileptiform events detected by continuous electrocorticographic monitoring via a brain-responsive neurostimulation system to supplement patient-maintained seizure diaries. METHODS:Data were retrospectively analyzed from a randomized controlled trial of brain-responsive ne...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106302

    authors: Quigg M,Skarpaas TL,Spencer DC,Fountain NB,Jarosiewicz B,Morrell MJ

    更新日期:2020-03-01 00:00:00

  • Distortion of the cortical motor map in patients with Unverricht-Lundborg disease: A combined TMS-MRI study.

    abstract:OBJECTIVE:To assess functional organization of the motor cortex in patients with Unverricht-Lundborg disease (EPM1A) using a combined neurophysiologic and imaging approach. METHODS:EPM1A patients underwent transcranial magnetic stimulation (TMS)-based cortical mapping of the motor hand area. Moreover, they performed n...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2020.106278

    authors: Rossi Sebastiano D,Visani E,Contarino VE,Panzica F,Duran D,D'Incerti L,Franceschetti S,Canafoglia L

    更新日期:2020-02-01 00:00:00

  • Personality functioning in adults with refractory epilepsy and community adults: Implications for health-related quality of life.

    abstract:INTRODUCTION:Prior research has shown that people with epilepsy are at risk for a poorer health-related quality of life (HRQOL). However, patients differ greatly in how well they adjust to their epilepsy. To better understand these differences, the present study examined the role of personality. More specifically, we e...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.106251

    authors: Rassart J,Luyckx K,Verdyck L,Mijnster T,Mark RE

    更新日期:2020-01-01 00:00:00

  • Genetic and clinical features of SCN8A developmental and epileptic encephalopathy.

    abstract:OBJECTIVE:We aim to delineate the genetic and clinical features of SCN8A developmental and epileptic encephalopathy. METHODS:Nine patients with SCN8A developmental and epileptic encephalopathy were included in this study. Genetic and clinical features and effectiveness of sodium channel blockers were assessed in patie...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.106222

    authors: Kim HJ,Yang D,Kim SH,Kim B,Kim HD,Lee JS,Choi JR,Lee ST,Kang HC

    更新日期:2019-12-01 00:00:00

  • Epileptiform activity promotes decreasing of Ca2+ conductivity of NMDARs, AMPARs, KARs, and voltage-gated calcium channels in Mg2+-free model.

    abstract::NMDA, AMPA, and kainate receptors are the principal excitatory receptors in the brain. These receptors have been considered as the main targets in the treatment of epilepsy in recent years. This work aimed to determine how the Ca2+ conductivity of ionotropic glutamate receptors and voltage-gated Ca2+ channels changes ...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.106224

    authors: Gaidin SG,Zinchenko VP,Teplov IY,Tuleukhanov ST,Kosenkov AM

    更新日期:2019-12-01 00:00:00

  • Pharmacometrics of clobazam in pediatrics: Prediction of effective clobazam doses for Dravet syndrome.

    abstract:OBJECTIVE:To describe the use of a population pharmacokinetic (PopPK) model incorporating weight and ontogeny to identify effective clobazam (CLB) dosing for use in a clinical trial in pediatric patients with Dravet syndrome. METHODS:Pharmacokinetic data were combined from 3 CLB trials (OV-1012, OV-1017, and study 301...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.106182

    authors: Tolbert D,Chu HM,Ette EI

    更新日期:2019-11-01 00:00:00

  • Allopregnanolone augments epileptiform activity of an in-vitro mouse hippocampal preparation in the first postnatal week.

    abstract::In the immature brain the neurotransmitter γ-amino butyric acid (GABA) mediates a membrane depolarization and can contribute to both, inhibition and excitation. Therefore the consequences of a positive modulation of GABA(A) receptors by neurosteroids on epileptiform activity are hard to predict. In order to analyze wh...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.106196

    authors: Sharopov S,Winkler P,Uehara R,Lombardi A,Halbhuber L,Okabe A,Luhmann HJ,Kilb W

    更新日期:2019-11-01 00:00:00

  • Effects of vitamin D and paricalcitol on epileptogenesis and behavioral properties of WAG/Rij rats with absence epilepsy.

    abstract:AIM:Vitamin D (Vit D) has been considered as a neurosteroid and has a pivotal role in neuroprotection including epilepsy. Vit D regulator acts via a Vit D receptor (VDR). WAG/Rij rats have a genetically epileptic model of absence epilepsy with comorbidity of depression. The aim of the present study was to investigate t...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.106208

    authors: Aygun H,Ayyildiz M,Agar E

    更新日期:2019-11-01 00:00:00

  • Use of dietary and herbal supplements in adult patients with epilepsy.

    abstract:PURPOSE:To study the extent and characteristics of dietary and herbal supplements use in a large cohort of adult patients with epilepsy. METHODS:This prospective study included 490 patients receiving care at a university epilepsy clinic. A number of variables, including demographics, characteristics of epilepsy and it...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.106168

    authors: Bosak M,Mołek P,Słowik A

    更新日期:2019-10-01 00:00:00

  • Genetic heterogeneity in infantile spasms.

    abstract::Infantile spasms (IS) is a developmental and epileptic encephalopathy with heterogeneous etiologies including many genetic causes. Genetic studies have identified pathogenic variants in over 30 genes as causes of IS. Many of these genetic causes are extremely rare, with only one reported incidence in an individual wit...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.106181

    authors: Muir AM,Myers CT,Nguyen NT,Saykally J,Craiu D,De Jonghe P,Helbig I,Hoffman-Zacharska D,Guerrini R,Lehesjoki AE,Marini C,Møller RS,Serratosa J,Štěrbová K,Striano P,von Spiczak S,Weckhuysen S,Mefford HC,EuroEPINOMICS-RE

    更新日期:2019-10-01 00:00:00

  • Cardiac changes in epileptic baboons with high-frequency microburst VNS therapy: A pilot study.

    abstract::The epileptic baboon provides a natural model of idiopathic generalized epilepsy and sudden unexpected death in epilepsy (SUDEP). We sought to evaluate autonomic differences, including heart rate (HR), heart rate variability (HRV) and corrected QT-duration (QTc) between two epileptic (EB1, EB2) and one control (CB) ba...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.106156

    authors: de la Garza MA,Poldiak D,Shade R,Salinas FS,Papanastassiou AM,Szabó CÁ

    更新日期:2019-09-01 00:00:00

  • Effects of ketamine on EEG in baboons with genetic generalized epilepsy.

    abstract::Ketamine, a noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist, used as an anesthetic has been reported to induce seizures both in humans and baboons predisposed to epilepsy. In this study, we aimed to characterize the acute effects of ketamine on scalp (sc-EEG) and intracranial EEG (ic-EEG) in the baboon...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.04.008

    authors: Gowda S,Szabó CÁ

    更新日期:2019-08-01 00:00:00

  • Long-term safety and efficacy following conversion to eslicarbazepine acetate monotherapy in adults with focal seizures.

    abstract:OBJECTIVE:To assess the long-term safety and efficacy of eslicarbazepine acetate (ESL) monotherapy in adults with focal seizures (FS). METHODS:Study 050 was a long-term, multicenter, open-label (OL) safety extension of two conversion-to-ESL monotherapy studies in adults with refractory FS. After participating in Study...

    journal_title:Epilepsy research

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.eplepsyres.2019.03.018

    authors: Chung S,Sinha SR,Shah A,Stern JM,Cheng H,Jung J,Grinnell T,Blum D

    更新日期:2019-07-01 00:00:00

  • 30 years of vagus nerve stimulation trials in epilepsy: Do we need neuromodulation-specific trial designs?

    abstract::Neuromodulation therapies represent an important treatment arm for patients with drug-resistant epilepsy (DRE) who are not candidates for resective surgery. Vagus nerve stimulation (VNS) - the neurostimulation modality in focus in this review - was the first available neuromodulatory therapy for DRE and was followed b...

    journal_title:Epilepsy research

    pub_type: 历史文章,杂志文章,评审

    doi:10.1016/j.eplepsyres.2019.02.004

    authors: Dibué-Adjei M,Kamp MA,Vonck K

    更新日期:2019-07-01 00:00:00

  • Effects of sinapic acid on hepatic cytochrome P450 3A2, 2C11, and intestinal P-glycoprotein on the pharmacokinetics of oral carbamazepine in rats: Potential food/herb-drug interaction.

    abstract::Dietary supplements, herbal medicines, and other foods may affect the pharmacokinetics and/or pharmacodynamics of carbamazepine (CBZ), which may possibly lead to potential drug-drug/herb-drug interactions, as CBZ has a narrow therapeutic window. Sinapic acid (SA) is a bioactive phytoconstituent used as a dietary suppl...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.03.012

    authors: Raish M,Ahmad A,Ansari MA,Alkharfy KM,Ahad A,Al-Jenoobi FI,Al-Mohizea AM,Khan A,Ali N

    更新日期:2019-07-01 00:00:00

  • Historical trend toward improved long-term outcome in childhood absence epilepsy.

    abstract::We retrospectively analyzed published studies to investigate historical trends in outcome of childhood absence epilepsy (CAE). We included patients based on onset of absence seizures in childhood, 3 Hz bilateral spike-wave discharges on EEG, and availability of seizure-free outcome data. The primary endpoint was seizu...

    journal_title:Epilepsy research

    pub_type: 历史文章,杂志文章,meta分析

    doi:10.1016/j.eplepsyres.2019.02.013

    authors: Morse E,Giblin K,Chung MH,Dohle C,Berg AT,Blumenfeld H

    更新日期:2019-05-01 00:00:00

  • Medicare claims can identify post-stroke epilepsy.

    abstract:OBJECTIVE:There have been no validated Medicare claims-based algorithms available to identify epilepsy by discrete etiology of stroke (e.g., post-stroke epilepsy, PSE) in community-dwelling elderly individuals, despite the increasing availability of large datasets. Our objective was to validate algorithms that detect w...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2019.02.002

    authors: Moura LMVR,Smith JR,Blacker D,Vogeli C,Schwamm LH,Hsu J

    更新日期:2019-03-01 00:00:00

  • Cannabis for refractory epilepsy in children: A review focusing on CDKL5 Deficiency Disorder.

    abstract::Severe paediatric epilepsies such as CDKL5 Deficiency Disorder (CDD) are extremely debilitating, largely due to the early-onset and refractory nature of the seizures. Existing treatment options are often ineffective and associated with a host of adverse effects, causing those that are affected to seek alternative trea...

    journal_title:Epilepsy research

    pub_type: 杂志文章,评审

    doi:10.1016/j.eplepsyres.2019.02.001

    authors: Dale T,Downs J,Olson H,Bergin AM,Smith S,Leonard H

    更新日期:2019-03-01 00:00:00

  • Levodropropizine suppresses seizure activity in rats with pentylenetetrazol-induced epilepsy.

    abstract:BACKGROUND:Millions of individuals worldwide suffer from epilepsy, and up to 25% of patients have seizures that are resistant to currently available antiepileptic drugs. Hence, there continues to be a need for more seizure medications that are effective yet tolerable. Levodropropizine (LVDP) is an established antitussi...

    journal_title:Epilepsy research

    pub_type: 杂志文章

    doi:10.1016/j.eplepsyres.2018.12.011

    authors: Erdogan MA,Yusuf D,Erdogan A,Erbas O

    更新日期:2019-02-01 00:00:00

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