解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:OBJECTIVES:To appraise effective predictors for COVID-19 mortality in a retrospective cohort study. METHODS:A total of 1270 COVID-19 patients, including 984 admitted in Sino French New City Branch (training and internal validation sets randomly split at 7:3 ratio) and 286 admitted in Optical Valley Branch (external va...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2020.1868564
更新日期:2021-12-01 00:00:00
abstract:BACKGROUND:Hyperglycaemia has emerged as an important risk factor for death in coronavirus disease 2019 (COVID-19). The aim of this study was to evaluate the association between blood glucose (BG) levels and in-hospital mortality in non-critically patients hospitalized with COVID-19. METHODS:This is a retrospective mu...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2020.1836566
更新日期:2021-12-01 00:00:00
abstract:INTRODUCTION:As individuals age, the prevalence of neurocognitive and mental health disorders increases. Current biomedical treatments do not completely address the management of these conditions. Despite new pharmacological therapy the challenges of managing these diseases remain.There is increasing evidence that the ...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2020.1808239
更新日期:2020-12-01 00:00:00
abstract::Statins are the first-line choice in Lipid-lowering therapy to reduce cardiovascular risk. In a continuous attempt to optimise treatment success, there is a need for additional research on genes and related molecular pathways that can determine the efficacy and toxicity of lipid-lowering drugs. Several variations with...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2020.1800074
更新日期:2020-12-01 00:00:00
abstract::In recent years a revival of interest has emerged in the health benefits of intermittent fasting and long-term fasting, as well as of other related nutritional strategies. In addition to meal size and composition a new focus on time and frequency of meals has gained attention. The present review will investigate the e...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2020.1770849
更新日期:2020-08-01 00:00:00
abstract::Objective: Investigation of the clinical potential of extensive phenotype data and machine learning (ML) in the prediction of mortality in acute coronary syndrome (ACS). Methods: The value of ML and extensive clinical data was analyzed in a retrospective registry study of 9066 consecutive ACS patients (January 2007 to...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2019.1596302
更新日期:2019-03-01 00:00:00
abstract::Aim: We investigated the outcomes of transcatheter (TAVR) and surgical aortic valve replacement (SAVR) in Finland during the last decade. Methods: The nationwide FinnValve registry included data from 6463 patients who underwent TAVR or SAVR with a bioprosthesis for aortic stenosis from 2008 to 2017. Results: The annua...
journal_title:Annals of medicine
pub_type: 临床试验,杂志文章
doi:10.1080/07853890.2019.1614657
更新日期:2019-01-01 00:00:00
abstract::Introduction: The use of dipeptidyl peptidase-4 inhibitors in hospitalized patients is an area of active research. We aimed to compare the efficacy and the safety of the basal-bolus insulin regimen versus linagliptin-basal insulin in non-critically ill non-cardiac surgery patients in a real-world setting. Methods: We ...
journal_title:Annals of medicine
pub_type: 杂志文章,多中心研究
doi:10.1080/07853890.2019.1613672
更新日期:2019-01-01 00:00:00
abstract::Aim: This meta-analysis study aimed to compare the efficacy and safety of TEVAR versus OCSR for TBAD patients.Methods: We systematically searched PubMed, EmBase, and the Cochrane library to identify studies compared the effectiveness of TEVAR and OCSR in TBAD patients from the inception up to July 2019. The summary re...
journal_title:Annals of medicine
pub_type: 杂志文章,meta分析
doi:10.1080/07853890.2019.1679874
更新日期:2019-01-01 00:00:00
abstract:AIM:Previous studies have shown that both triglyceride glucose (TyG) and haemoglobin glycation indexes (HGI) are predictors of cardiovascular risk. However, the prognostic value of TyG index and HGI in patients with type 2 diabetes mellitus (T2DM) and stable coronary artery disease (CAD) is not determined. METHODS:We ...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2018.1523549
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:Evidence on the association between depression, antidepressant use and venous thromboembolism (VTE) risk is conflicting. We conducted a systematic review and meta-analysis of published observational studies evaluating the associations of depression and antidepressant use with VTE risk. DESIGN:Eligible studies ...
journal_title:Annals of medicine
pub_type: 杂志文章,meta分析
doi:10.1080/07853890.2018.1500703
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:To assess the relationship between the FRAX index and the Barthel index/MiniMental State Examination in older people. PATIENTS AND METHODS:Observational descriptive study. Demographic data, comorbidity, dependency and cognitive state, and risk of osteoporotic fracture were collected. RESULTS:A total of 375 ...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2018.1505052
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:The association between otitis media and vestibular symptoms has been hypothesized in the past. Thus, in this study, we aimed to critically analyze (based in a systematic review of the literature) whether patients who have otitis media are at greater risk of developing vestibular impairment or not. METHODS:...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2018.1470665
更新日期:2018-08-01 00:00:00
abstract::Inflammatory bowel diseases (IBD) are chronic inflammatory conditions of the gastrointestinal tract encompassing two main clinical entities: Crohn's disease (CD) and ulcerative colitis (UC). These disorders are characterized by various grades of tissue damage and development of local complications and extra-intestinal...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890.2018.1490025
更新日期:2018-08-01 00:00:00
abstract::Atrial fibrillation (AF) is the most prevalent arrhythmia and is associated with an increased risk of ischemic stroke (IS) and systemic embolism (SE). Stroke prevention is a key element for the overall management of AF patients. The non-vitamin K antagonist oral anticoagulants (NOACs), such as dabigatran, rivaroxaban,...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890.2018.1460489
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:We aimed to assess the prospective association of serum albumin with venous thromboembolism (VTE) risk and evaluate if the association is independent of or modified by inflammation, as measured by high sensitivity C-reactive protein (hsCRP). DESIGN:We analysed data of 2176 men aged 42-61 years free from VTE in...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2018.1441537
更新日期:2018-05-01 00:00:00
abstract::The Human Genome Project (HGP), as the primary sequencing of the human genome, lasted more than one decade to be completed using the traditional Sanger's method. At present, next-generation sequencing (NGS) technology could provide the genome sequence data in hours. NGS has also decreased the expense of sequencing; th...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890.2017.1392595
更新日期:2018-03-01 00:00:00
abstract::Vaccines are considered to be one of the greatest public health achievements of the last century. Depending on the biology of the infection, the disease to be prevented, and the targeted population, a vaccine may require the induction of different adaptive immune mechanisms to be effective. Understanding the basic con...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890.2017.1407035
更新日期:2018-03-01 00:00:00
abstract::Heart failure syndrome results from compensatory mechanisms that operate to restore - back to normal - the systemic perfusion pressure. Sympathetic overactivity plays a pivotal role in heart failure; norepinephrine contributes to maintenance of the systemic blood pressure and increasing preload. Cardiac norepinephrine...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890.2017.1282168
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Female sex, old age, and time to cardioversion increase the risk of thromboembolic complications (TEC) after cardioversion of atrial fibrillation (AF) < 48 h. The interaction of these variables is not known. We investigated the interaction of sex, age, and time to electrical cardioversion (ECV) on TEC in ant...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2016.1267869
更新日期:2017-05-01 00:00:00
abstract::Despite striking extensions of lifespan, leading causes of death in most countries now constitute chronic, degenerative diseases which outpace the capacity of health systems. Cardiovascular disease is the most common cause of death in both developed and undeveloped countries. In America, nearly half of the adult popul...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890.2016.1271957
更新日期:2017-05-01 00:00:00
abstract::Despite intensive research in spondyloarthritis pathogenesis, some important questions still remain unanswered, particularly concerning enthesis new bone formation. Several evidences suggest that it prevalently occurs by endochondral ossification, however it remains to identify factors that can induce and influence it...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.1080/07853890.2016.1243802
更新日期:2017-05-01 00:00:00
abstract:INTRODUCTION:Ambient air pollution is associated with adverse cardiovascular events. This meta-analysis aimed to investigate the short-term association between air pollution and cardiovascular effects on healthy volunteers. METHODS:We searched databases to identify randomized trials with controlled human exposures to ...
journal_title:Annals of medicine
pub_type: 杂志文章,meta分析
doi:10.1080/07853890.2016.1252054
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Heart rate (HR), heart rate variability (HRV), and inflammation are all associated with cardiovascular morbidity and mortality. The aim of this study was to assess potential interrelationships between these parameters in a young and healthy population. METHODS:Healthy individuals aged 25-41 years were inclu...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2016.1226512
更新日期:2017-02-01 00:00:00
abstract:INTRODUCTION:Ischemic stroke (IS) in a young patient is a disaster and recurrent cardiovascular events could add further impairment. Identifying patients with high risk of such events is therefore important. The prognostic relevance of ECG for this population is unknown. MATERIALS AND METHODS:A total of 690 IS patient...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2016.1202443
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Finnish type of hereditary gelsolin amyloidosis (AGel amyloidosis) is an autosomal dominant disorder. Until recently, there has only been little knowledge of fatal complications of the disease and its possible impact on the patients' life span. METHODS:We identified 272 deceased patients based on patient in...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.1080/07853890.2016.1177197
更新日期:2016-08-01 00:00:00
abstract:IMPORTANCE:There is limited information about the durability of glycaemic control when different oral glucose-lowering therapies (GLTs) are used as add-on treatments to metformin (MET) in patients with type 2 diabetes mellitus (T2DM). OBJECTIVE:To compare time to treatment failure between different classes of oral GLT...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853890.2016.1157263
更新日期:2016-01-01 00:00:00
abstract::Small cell carcinoma (SCC) of the prostate is an uncommon condition; there are very few cases in which presenting symptoms are consistent with Cushing Syndrome (CS). We report a new case in which CS triggers the suspicion of an SCC of the prostate and a review of the published cases of SCC of the prostate presenting w...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.3109/07853890.2016.1168936
更新日期:2016-01-01 00:00:00
abstract::The Benchmarking Controlled Trial (BCT) is a novel concept which covers all observational studies aiming to assess effectiveness. BCTs provide evidence of the comparative effectiveness between health service providers, and of effectiveness due to particular features of the health and social care systems. BCTs compleme...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853890.2015.1027255
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Several studies have suggested that the occurrence of severe hypoglycemia during sleep may be more dangerous for cardiac arrhythmia than that in the day-time. METHODS:We performed a retrospective study between January 2006 and March 2012 to assess electrocardiograms during severe hypoglycemia in patients wi...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853890.2015.1017528
更新日期:2015-05-01 00:00:00
abstract:INTRODUCTION:The association between sleep disturbances and cardiometabolic diseases has been understudied in blacks with metabolic syndrome. METHODS:This study is a cross-sectional analysis of the Metabolic Syndrome Outcome Study (MetSO) trial. We assessed insomnia symptoms, sleep duration, and risk for sleep apnea. ...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853890.2015.1015601
更新日期:2015-05-01 00:00:00
abstract:INTRODUCTION:We studied prevalence of hypovitaminosis D, its determinants, and whether achievement of recommended dietary vitamin D intake (10 μg/d) is associated with absence of hypovitaminosis D in adults. METHODS:The study is part of the Cardiovascular Risk in Young Finns Study. We collected serum samples of 25-hyd...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853890.2015.1020860
更新日期:2015-05-01 00:00:00
abstract:INTRODUCTION:Maternal obesity has long-term consequences for the offspring's later health, including an increased risk of type 2 diabetes and cardiovascular disease. The underlying mechanisms explaining these associations are, however, not fully understood. METHODS:A total of 2003 individuals from the Helsinki Birth C...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853890.2015.1004360
更新日期:2015-03-01 00:00:00
abstract:AIM:To evaluate the effects of canrenone compared to placebo on blood pressure control, some non-conventional biomarkers in cardiovascular stratification, and on metalloproteinases in patients affected by metabolic syndrome. METHODS:A total of 156 Caucasian patients were treated with placebo or canrenone, 50 mg once a...
journal_title:Annals of medicine
pub_type: 杂志文章,随机对照试验
doi:10.3109/07853890.2014.969303
更新日期:2015-02-01 00:00:00
abstract::Idiopathic pulmonary fibrosis (IPF) is the most common and lethal form of idiopathic interstitial pneumonia. The disease, which occurs primarily in middle-aged and older adults, is thought to arise following an aberrant reparative response to alveolar epithelial cell injury characterized by secretion of excessive amou...
journal_title:Annals of medicine
pub_type: 杂志文章,评审
doi:10.3109/07853890.2014.982165
更新日期:2015-02-01 00:00:00
abstract::This meta-analysis examined the effect of probiotics on the reduction of lipid components and coexisting risk factors associated with cardiovascular disease. All randomized controlled trials published in English on PubMed and Scopus from 2000 to 2014 were systematically searched. Using the PEDro scale to assess the qu...
journal_title:Annals of medicine
pub_type: 杂志文章,meta分析,评审
doi:10.3109/07853890.2015.1071872
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Finnish type of hereditary gelsolin amyloidosis (FGA) is one of the most common diseases of Finnish disease heritage. Existing FGA knowledge is based only on smaller patient series, so our aim was to elucidate the natural course of the disease in a comprehensive sample of patients and to build up a national ...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853890.2015.1075063
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:Undetermined strokes with an embolic pattern (USEP) represent a common phenotype. We assessed their frequency and compared USEP with cardioembolic stroke with a known source and non-cardioembolic stroke etiology. METHODS:Study patients were 540 consecutive ischemic stroke patients admitted to Helsinki Uni...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853890.2015.1057612
更新日期:2015-01-01 00:00:00
abstract:INTRODUCTION:The objective of the present study was to examine the association between low-grade albuminuria and hearing impairment in the non-diabetic population. MATERIALS AND METHODS:Data from the Korean National Health and Nutrition Examination Survey 2011-2013 were used in the analyses. Participants were excluded...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853890.2015.1093163
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE AND METHODS:The impact of the rs9939609 FTO variant on cardiovascular events was investigated in the 19-year follow-up of subjects recruited to the OPERA study. RESULTS:A total of 212 cardiovascular disease (CVD) and 152 coronary heart disease (CHD) events or deaths occurred during follow-up. The logistic re...
journal_title:Annals of medicine
pub_type: 杂志文章
doi:10.3109/07853890.2015.1091088
更新日期:2015-01-01 00:00:00