听力与言语-语言病理学

行为科学

医学伦理学

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  • Metolazone upregulates mitochondrial chaperones and extends lifespan in Caenorhabditis elegans.

    abstract::Accumulating studies have argued that the mitochondrial unfolded protein response (UPRmt) is a mitochondrial stress response that promotes longevity in model organisms. In the present study, we screened an off-patent drug library to identify compounds that activate UPRmt using a mitochondrial chaperone hsp-6::GFP repo...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-020-09907-6

    authors: Ito A,Zhao Q,Tanaka Y,Yasui M,Katayama R,Sun S,Tanimoto Y,Nishikawa Y,Kage-Nakadai E

    更新日期:2021-02-01 00:00:00

  • Background radiation impacts human longevity and cancer mortality: reconsidering the linear no-threshold paradigm.

    abstract::The current linear no-threshold paradigm assumes that any exposure to ionizing radiation carries some risk, thus every effort should be made to maintain the exposures as low as possible. We examined whether background radiation impacts human longevity and cancer mortality. Our data covered the entire US population of ...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-020-09909-4

    authors: David E,Wolfson M,Fraifeld VE

    更新日期:2021-01-22 00:00:00

  • Low-dose ionizing radiation as a hormetin: experimental observations and therapeutic perspective for age-related disorders.

    abstract::Hormesis is any kind of biphasic dose-response when low doses of some agents are beneficial while higher doses are detrimental. Radiation hormesis is the most thoroughly investigated among all hormesis-like phenomena, in particular in biogerontology. In this review, we aimed to summarize research evidence supporting h...

    journal_title:Biogerontology

    pub_type: 杂志文章,评审

    doi:10.1007/s10522-020-09908-5

    authors: Vaiserman A,Cuttler JM,Socol Y

    更新日期:2021-01-09 00:00:00

  • D-galactose: a model of accelerated ageing sufficiently sensitive to reflect preventative efficacy of an antioxidant treatment.

    abstract::Considering that the phenomenon of accelerated ageing contributes to early onset of various chronic diseases, modelling of the relevant dysregulated systems or responses is vital for research aimed at identification of potential therapeutic targets. Here, we aimed to establish a model capable of simulating the redox a...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-020-09891-x

    authors: Ross KS,Smith C

    更新日期:2020-12-01 00:00:00

  • Effects of lifelong exercise and aging on the blood metabolic fingerprint of rats.

    abstract::Regular exercise is an important part of a healthy lifestyle, as it helps maintain a healthy weight and reduces the risk of chronic diseases. We explored the effects of lifelong exercise and aging on rat metabolism through a metabolomics approach. Thirty-six rats were divided into four equal groups: exercise during th...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-020-09871-1

    authors: Tzimou A,Benaki D,Nikolaidis S,Mikros E,Taitzoglou I,Mougios V

    更新日期:2020-10-01 00:00:00

  • Preadipocyte secretory factors differentially modulate murine macrophage functions during aging which are reversed by the application of phytochemical EGCG.

    abstract::The present study aimed at evaluating the role of senescent cell microenvironment as an extrinsic causal factor for altered age-associated macrophage functions, and that whether such changes could be ameliorated by the application of tea catechin epigallocatechin gallate (EGCG). To ascertain this, we analyzed the impa...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-020-09861-3

    authors: Kumar R,Sharma A,Padwad Y,Sharma R

    更新日期:2020-06-01 00:00:00

  • Dysregulations of mitochondrial quality control and autophagic flux at an early age lead to progression of sarcopenia in SAMP8 mice.

    abstract::The senescence-accelerated mouse (SAM) prone 8 (SAMP8) has been demonstrated for muscular aging research including sarcopenia, but its underlying mechanisms remain scarce. Physiological indices and histology of skeletal muscle were analyzed in SAMP8 mice at different ages. SAMP8 mice exhibited typical features of sarc...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-020-09867-x

    authors: Liu HW,Chang YC,Chan YC,Hu SH,Liu MY,Chang SJ

    更新日期:2020-06-01 00:00:00

  • Metabolic remodelling of mice by hypoxic-hypercapnic environment: imitating the naked mole-rat.

    abstract::We hypothesised that hypoxic-hypercapnic environment (HHE) could induce metabolic suppression and associated benefits for health and longevity, as observed in the naked-mole rat (NMR). We developed a model of self-produced HHE (similar to a natural habitat of NMRs), which is simple, reliable and natural, and does not ...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-019-09848-9

    authors: Tolstun DA,Knyazer A,Tushynska TV,Dubiley TA,Bezrukov VV,Fraifeld VE,Muradian KK

    更新日期:2020-04-01 00:00:00

  • Increase in hippocampal histone H3K9me3 is negatively correlated with memory in old male mice.

    abstract::With advancing age, memory declines through different mechanisms including dysregulation of expression of synaptic plasticity genes in hippocampus. Increasing evidences suggest that these synaptic plasticity genes are regulated through epigenetic modifications. Recently we have reported that the neuronal immediate ear...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-019-09850-1

    authors: Kushwaha A,Thakur MK

    更新日期:2020-04-01 00:00:00

  • A 2D analysis of correlations between the parameters of the Gompertz-Makeham model (or law?) of relationships between aging, mortality, and longevity.

    abstract::When mortality (μ), aging rate (γ) and age (t) are treated according to the Gompertz model μ(t) = μ0eγt (GM), any mean age corresponds to a manifold of paired reciprocally changing μ0 and γ. Therefore, any noisiness of data used to derive GM parameters makes them negatively correlated. Besides this artifactual factor ...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-019-09828-z

    authors: Golubev A

    更新日期:2019-12-01 00:00:00

  • Genetic background, epigenetic factors and dietary interventions which influence human longevity.

    abstract::Longevity is mainly conditioned by genetic, epigenetic and environmental factors. Different genetic modifications seem to be positively associated to longevity, including SNPs in SIRT1, APOE, FOXO3A, ACE, ATM, NOS1 and NOS2 gene. Epigenetic changes as DNA hyper- and hypo-methylation influence significantly human longe...

    journal_title:Biogerontology

    pub_type: 杂志文章,评审

    doi:10.1007/s10522-019-09824-3

    authors: Costa D,Scognamiglio M,Fiorito C,Benincasa G,Napoli C

    更新日期:2019-10-01 00:00:00

  • Generation of a novel model of primary human cell senescence through Tenovin-6 mediated inhibition of sirtuins.

    abstract::Cell senescence, a state of cell cycle arrest and altered metabolism with enhanced pro-inflammatory secretion, underlies at least some aspects of organismal ageing. The sirtuin family of deacetylases has been implicated in preventing premature ageing; sirtuin overexpression or resveratrol-mediated activation of sirtui...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-018-09792-0

    authors: Walters HE,Cox LS

    更新日期:2019-06-01 00:00:00

  • Optimisation of a screening platform for determining IL-6 inflammatory signalling in the senescence-associated secretory phenotype (SASP).

    abstract::Cellular senescence has been shown to be sufficient for the development of multiple age-related pathologies. Senescent cells adopt a secretory phenotype (the SASP) which comprises a large number of pro-inflammatory cytokines, chemokines and proteases. The SASP itself is thought to be causative in many pathologies of a...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-019-09796-4

    authors: Rolt A,Nair A,Cox LS

    更新日期:2019-06-01 00:00:00

  • Convergence of longevity and immunity: lessons from animal models.

    abstract::An increasing amount of data implicate immunity-mostly innate immunity-in the ageing process; both during healthy ageing as well as in neurodegenerative diseases. Despite the aetiology however, the underlying mechanisms are poorly understood. Here we review what we know from model organisms (worms, flies and mice) on ...

    journal_title:Biogerontology

    pub_type: 杂志文章,评审

    doi:10.1007/s10522-019-09801-w

    authors: Xia J,Gravato-Nobre M,Ligoxygakis P

    更新日期:2019-06-01 00:00:00

  • Epigallocatechin gallate suppresses premature senescence of preadipocytes by inhibition of PI3K/Akt/mTOR pathway and induces senescent cell death by regulation of Bax/Bcl-2 pathway.

    abstract::The phytochemical epigallocatechin gallate (EGCG) has been reported to alleviate age-associated immune disorders and organ dysfunction. However, information regarding the mechanistic role of EGCG in the suppression of cellular senescence is limited. The present study thus assessed the effects and underlying mechanisms...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-018-9785-1

    authors: Kumar R,Sharma A,Kumari A,Gulati A,Padwad Y,Sharma R

    更新日期:2019-04-01 00:00:00

  • L-Carnitine inhibits the senescence-associated secretory phenotype of aging adipose tissue by JNK/p53 pathway.

    abstract::Senescence-associated secretory phenotype (SASP) plays a role in aging adipose tissue dysfunction by directly promoting chronic inflammation. The JNK/p53 pathway was reported as a potential mechanism that mediates SASP. In this study, we investigated the effects of L-carnitine, an inhibitor of the JNK/p53 pathway in a...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-018-9787-z

    authors: Yang LW,Song M,Li YL,Liu YP,Liu C,Han L,Wang ZH,Zhang W,Xing YQ,Zhong M

    更新日期:2019-04-01 00:00:00

  • Bridging the gap between the laboratory and the clinic for patients with sarcopenia.

    abstract::Sarcopenia-the age-related loss of skeletal muscle mass and strength-is a major public health issue. Sarcopenia is associated with an increased risk of falls, disability, dependency, institutionalization, hospital stay and early death. Finding interventions to stabilize, reverse or prevent sarcopenia is therefore a ke...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-018-09793-z

    authors: Witham MD

    更新日期:2019-04-01 00:00:00

  • Gene expression hallmarks of cellular ageing.

    abstract::Ageing leads to dramatic changes in the physiology of many different tissues resulting in a spectrum of pathology. Nonetheless, many lines of evidence suggest that ageing is driven by highly conserved cell intrinsic processes, and a set of unifying hallmarks of ageing has been defined. Here, we survey reports of age-l...

    journal_title:Biogerontology

    pub_type: 杂志文章,评审

    doi:10.1007/s10522-018-9750-z

    authors: Frenk S,Houseley J

    更新日期:2018-12-01 00:00:00

  • Dissecting cause and effect in host-microbiome interactions using the combined worm-bug model system.

    abstract::High-throughput molecular studies are greatly advancing our knowledge of the human microbiome and its specific role in governing health and disease states. A myriad of ongoing studies aim at identifying links between microbial community disequilibria (dysbiosis) and human diseases. However, due to the inherent complex...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-018-9752-x

    authors: Ezcurra M

    更新日期:2018-12-01 00:00:00

  • The impact of aging on CD4+ T cell responses to influenza infection.

    abstract::CD4+ T cells are important for generating high quality and robust immune responses to influenza infection. Immunosenescence that occurs with aging, however, compromises the ability of CD4+ T cells to differentiate into functional subsets resulting in a multitude of dysregulated responses namely, delayed viral clearanc...

    journal_title:Biogerontology

    pub_type: 杂志文章,评审

    doi:10.1007/s10522-018-9754-8

    authors: Lorenzo EC,Bartley JM,Haynes L

    更新日期:2018-12-01 00:00:00

  • Applying parametric models to survival data: tradeoffs between statistical significance, biological plausibility, and common sense.

    abstract::Parametric models for survival data help to differentiate aging from other lifespan determinants. However, such inferences suffer from small sizes of experimental animal samples and variable animals handling by different labs. We analyzed control data from a single laboratory where interventions in murine lifespan wer...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-018-9759-3

    authors: Golubev A,Panchenko A,Anisimov V

    更新日期:2018-10-01 00:00:00

  • The secretory phenotype of senescent astrocytes isolated from Wistar newborn rats changes with anti-inflammatory drugs, but does not have a short-term effect on neuronal mitochondrial potential.

    abstract::In the central nervous system (CNS), senescent astrocytes have been associated with neurodegeneration. Senescent cells secrete a complex mixture of pro-inflammatory factors, which are collectively called Senescence Associated Secretory Phenotype (SASP). The SASP components can vary depending on the cell type, senescen...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-018-9767-3

    authors: Maciel-Barón LÁ,Morales-Rosales SL,Silva-Palacios A,Rodríguez-Barrera RH,García-Álvarez JA,Luna-López A,Pérez VI,Torres C,Königsberg M

    更新日期:2018-10-01 00:00:00

  • Mitochondria, its DNA and telomeres in ageing and human population.

    abstract::In the last decades, studies about ageing have become more essential as our population grows older. The incidence of age-related diseases increases, which pose challenges both for societies and individuals in terms of life quality and economic impact. Understanding ageing and ageing-related processes will help us to s...

    journal_title:Biogerontology

    pub_type: 杂志文章,评审

    doi:10.1007/s10522-018-9748-6

    authors: Zole E,Ranka R

    更新日期:2018-07-01 00:00:00

  • How regularities of mortality statistics explain why we age despite having potentially ageless somatic stem cells.

    abstract::Researchers working in the area of ageing have found numerous manifestations of this process at the molecular biological level, including DNA and protein damage, accumulation of metabolic by-products, lipids peroxidation, macromolecular cross-linking, non-enzymatic glycosylation, anti-oxidant/pro-oxidant misbalance, r...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-017-9728-2

    authors: Khalyavkin AV,Krut'ko VN

    更新日期:2018-02-01 00:00:00

  • Accumulation of glycated proteins suggesting premature ageing in lamin B receptor deficient mice.

    abstract::Accumulation of advanced glycation end products (AGEs) is accompanied by increased free radical activity which contributes to ageing and the development or worsening of degenerative diseases. Apart from other physiological factors, AGEs are also an important biomarker for premature ageing. Here we report protein modif...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-017-9733-5

    authors: Hause F,Schlote D,Simm A,Hoffmann K,Santos AN

    更新日期:2018-02-01 00:00:00

  • Daily chronomics of proteomic profile in aging and rotenone-induced Parkinson's disease model in male Wistar rat and its modulation by melatonin.

    abstract::Aging is associated with changes in several basic parameters of circadian timing system (CTS) in mammals leading to circadian dysfunction. We had reported earlier that upon aging and in rotenone induced Parkinson's disease (RIPD) rat model there were significant alterations in the core clock genes expression levels an...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-017-9711-y

    authors: Jagota A,Mattam U

    更新日期:2017-08-01 00:00:00

  • Mitochondrial biogenesis and neural differentiation of human iPSC is modulated by idebenone in a developmental stage-dependent manner.

    abstract::Idebenone, the synthetic analog of coenzyme Q10 can improve electron transport in mitochondria. Therefore, it is used in the treatment of Alzheimer's disease and other cognitive impairments. However, the mechanism of its action on neurodevelopment is still to be elucidated. Here we demonstrate that the cellular respon...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-017-9718-4

    authors: Augustyniak J,Lenart J,Zychowicz M,Stepien PP,Buzanska L

    更新日期:2017-08-01 00:00:00

  • Different transcriptional profiling between senescent and non-senescent human coronary artery endothelial cells (HCAECs) by Omeprazole and Lansoprazole treatment.

    abstract::Recent evidence suggests that high dose and/or long term use of proton pump inhibitors (PPIs) may increase the risk of adverse cardiovascular events in older patients, but mechanisms underlying these detrimental effects are not known. Taking into account that the senescent endothelial cells have been implicated in the...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-016-9675-3

    authors: Costarelli L,Giacconi R,Malavolta M,Basso A,Piacenza F,Provinciali M,Maggio MG,Corsonello A,Lattanzio F

    更新日期:2017-04-01 00:00:00

  • Increase in tumor suppressor Arf compensates gene dysregulation in in vitro aged adipocytes.

    abstract::Deterioration of adipocyte function due to increased oxidative stress predisposes patients to metabolic disorders in advanced age. However, the roles of tumor suppressors in such conditions remain largely unknown. Therefore, we aimed to address their dynamics in aged adipocytes using a long-term culture model. We comp...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-016-9661-9

    authors: Hasan AU,Ohmori K,Hashimoto T,Kamitori K,Yamaguchi F,Konishi K,Noma T,Igarashi J,Yamashita T,Hirano K,Tokuda M,Minamino T,Nishiyama A,Kohno M

    更新日期:2017-02-01 00:00:00

  • Insulin/insulin-like growth factor-1 signalling (IIS) based regulation of lifespan across species.

    abstract::An organism's well-being is facilitated by numerous molecular and biochemical pathways that ensure homeostasis within cells and tissues. Aging causes a gradual let-down in the maintenance of homeostasis due to various endogenous and environmental challenges, leading to amassing of damages, functional deterioration of ...

    journal_title:Biogerontology

    pub_type: 杂志文章,评审

    doi:10.1007/s10522-016-9670-8

    authors: Mathew R,Pal Bhadra M,Bhadra U

    更新日期:2017-02-01 00:00:00

  • Age-dependent differential expression of death-associated protein 6 (Daxx) in various peripheral tissues and different brain regions of C57BL/6 male mice.

    abstract::Death-associated protein 6 (DAXX) is a ubiquitous protein implicated in various cellular processes such as apoptosis, tumorigenesis, development and transcription. The role of DAXX is however ambiguous and many contradictory results regarding its function in apoptosis upon various cellular stresses are described in th...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-016-9651-y

    authors: Lessard-Beaudoin M,Laroche M,Demers MJ,Duclos C,Denault JB,Grenier G,Riechers SP,Wanker EE,Graham RK

    更新日期:2016-11-01 00:00:00

  • Daily NO rhythms in peripheral clocks in aging male Wistar rats: protective effects of exogenous melatonin.

    abstract::In mammals suprachiasmatic nucleus (SCN), acts as a light entrainable master clock and by generation of temporal oscillations regulates the peripheral organs acting as autonomous clocks resulting in overt behavioral and physiological rhythms. SCN also controls synthesis and release of melatonin (hormonal message for d...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-016-9656-6

    authors: Vinod C,Jagota A

    更新日期:2016-11-01 00:00:00

  • LPS alters pattern of sickness behavior but does not affect glutathione level in aged male rats.

    abstract::Behavioral symptoms of sickness, such as fever and motor activity are a coordinated set of changes that develop during infection. The aim of study was to compare the sickness behaviour (SB) in healthy old and young rats treated with pyrogenic dose of endotoxin and to check their glutathione level. Before experimentati...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-016-9636-x

    authors: Wrotek S,Jędrzejewski T,Nowakowska A,Kozak W

    更新日期:2016-08-01 00:00:00

  • The impact of obesity on skeletal muscle strength and structure through adolescence to old age.

    abstract::Obesity is associated with functional limitations in muscle performance and increased likelihood of developing a functional disability such as mobility, strength, postural and dynamic balance limitations. The consensus is that obese individuals, regardless of age, have a greater absolute maximum muscle strength compar...

    journal_title:Biogerontology

    pub_type: 杂志文章,评审

    doi:10.1007/s10522-015-9626-4

    authors: Tomlinson DJ,Erskine RM,Morse CI,Winwood K,Onambélé-Pearson G

    更新日期:2016-06-01 00:00:00

  • Biomarkers of aging, life span and spontaneous carcinogenesis in the wild type and HER-2 transgenic FVB/N female mice.

    abstract::FVB/N wild type and transgenic HER-2/neu FVB/N female mice breed at N.N. Petrov Research Institute of Oncology were under observation until natural death without any special treatment. Age-related dynamics of body weight, food consumption and parameters of carbohydrate and lipid metabolism, level of nitric oxide, malo...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-015-9611-y

    authors: Panchenko AV,Popovich IG,Trashkov AP,Egormin PA,Yurova MN,Tyndyk ML,Gubareva EA,Artyukin IN,Vasiliev AG,Khaitsev NV,Zabezhinski MA,Anisimov VN

    更新日期:2016-04-01 00:00:00

  • Puzzling role of genetic risk factors in human longevity: "risk alleles" as pro-longevity variants.

    abstract::Complex diseases are major contributors to human mortality in old age. Paradoxically, many genetic variants that have been associated with increased risks of such diseases are found in genomes of long-lived people, and do not seem to compromise longevity. Here we argue that trade-off-like and conditional effects of ge...

    journal_title:Biogerontology

    pub_type: 杂志文章,评审

    doi:10.1007/s10522-015-9600-1

    authors: Ukraintseva S,Yashin A,Arbeev K,Kulminski A,Akushevich I,Wu D,Joshi G,Land KC,Stallard E

    更新日期:2016-02-01 00:00:00

  • Hutchinson-Gilford progeria syndrome as a model for vascular aging.

    abstract::Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disorder caused by a de novo genetic mutation that leads to the accumulation of a splicing isoform of lamin A termed progerin. Progerin expression alters the organization of the nuclear lamina and chromatin. The life expectancy of HGPS patients is severe...

    journal_title:Biogerontology

    pub_type: 杂志文章,评审

    doi:10.1007/s10522-015-9602-z

    authors: Brassard JA,Fekete N,Garnier A,Hoesli CA

    更新日期:2016-02-01 00:00:00

  • Reproduction, aging and mortality rate in social subterranean mole voles (Ellobius talpinus Pall.).

    abstract::Eusocial subterranean rodents of the Bathyergidae family have enormous longevity. The long lifespan of these species is associated with negligible senescence, that is, an absence of the signs of age-related deterioration in physical condition. The question arises as to whether these features are unique to eusocial Bat...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-015-9592-x

    authors: Novikov E,Kondratyuk E,Petrovski D,Titova T,Zadubrovskaya I,Zadubrovskiy P,Moshkin M

    更新日期:2015-12-01 00:00:00

  • Muscle-specificity of age-related changes in markers of autophagy and sphingolipid metabolism.

    abstract::Our previous findings indicate that the gastrocnemius muscle of aging rats exhibits impairments of muscle quality (force/unit muscle tissue) and autophagy and increased sarcoplasmic reticulum stress. The purpose of this study was to examine age-related changes in soleus muscle contractility and in markers of autophagy...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-015-9598-4

    authors: Russ DW,Boyd IM,McCoy KM,McCorkle KW

    更新日期:2015-12-01 00:00:00

  • A correlation of reactive oxygen species accumulation by depletion of superoxide dismutases with age-dependent impairment in the nervous system and muscles of Drosophila adults.

    abstract::The theory that accumulation of reactive oxygen species (ROS) in internal organs is a major promoter of aging has been considered negatively. However, it is still controversial whether overexpression of superoxide dismutases (SODs), which remove ROS, extends the lifespan in Drosophila adults. We examined whether ROS a...

    journal_title:Biogerontology

    pub_type: 杂志文章

    doi:10.1007/s10522-015-9570-3

    authors: Oka S,Hirai J,Yasukawa T,Nakahara Y,Inoue YH

    更新日期:2015-08-01 00:00:00

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