abstract：:Mutations in the granulin gene (GRN) cause familial frontotemporal dementia. Understanding the structural brain changes in presymptomatic GRN carriers would enforce the use of neuroimaging biomarkers for early diagnosis and monitoring. We studied 100 presymptomatic GRN mutation carriers and 94 noncarriers from the Gen...

journal_title：NeuroImage. Clinical

authors： Borrego-Écija S,Sala-Llonch R,van Swieten J,Borroni B,Moreno F,Masellis M,Tartaglia C,Graff C,Galimberti D,Laforce R Jr,Rowe JB,Finger E,Vandenberghe R,Tagliavini F,de Mendonça A,Santana I,Synofzik M,Ducharme S,Levin

更新日期：2020-12-29 00:00:00

abstract：:Cerebral amyloid angiopathy (CAA) is a major cause of intracerebral hemorrhage and neurological decline in the elderly. CAA results in focal brain lesions, but the influence on global brain functioning needs further investigation. Here we study functional brain connectivity in patients with Dutch type hereditary CAA u...

journal_title：NeuroImage. Clinical

authors： Drenth N,van der Grond J,Rombouts SARB,van Buchem MA,Terwindt GM,Wermer MJH,Chhatwal JP,Gurol ME,Greenberg SM,van Rooden S

更新日期：2020-12-24 00:00:00

abstract：INTRODUCTION:Cognitive complaints are common shortly after mild traumatic brain injury (mTBI) but may persist up to years. Age-related cognitive decline can worsen these symptoms. However, effects of age on mTBI sequelae have scarcely been investigated. METHODS:Fifty-four mTBI patients (median age: 35 years, range 19-...

journal_title：NeuroImage. Clinical

authors： Bittencourt-Villalpando M,van der Horn HJ,Maurits NM,van der Naalt J

更新日期：2020-12-22 00:00:00

abstract：BACKGROUND AND PURPOSE:Cognitive impairment is a common consequence of stroke, and the rewiring of the surviving brain circuits might contribute to cognitive recovery. Studies investigating how the functional connectivity of networks change across time and whether their remapping relates to cognitive recovery in stroke...

journal_title：NeuroImage. Clinical

authors： Vicentini JE,Weiler M,Casseb RF,Almeida SR,Valler L,de Campos BM,Li LM

更新日期：2020-12-17 00:00:00

abstract：:The neurophysiology of face processing has been studied extensively in the context of social impairments associated with autism spectrum disorder (ASD), but the existing studies have concentrated mainly on univariate analyses of responses to upright faces, and, less frequently, inverted faces. The small number of exis...

journal_title：NeuroImage. Clinical

authors： Nunes AS,Mamashli F,Kozhemiako N,Khan S,McGuiggan NM,Losh A,Joseph RM,Ahveninen J,Doesburg SM,Hämäläinen MS,Kenet T

更新日期：2020-11-30 00:00:00

abstract：:This study investigated the functional brain connectome architecture in patients with Posterior Cortical Atrophy (PCA). Eighteen PCA patients and 29 age- and sex- matched healthy controls were consecutively recruited in a specialized referral center. Participants underwent neurologic examination, cerebrospinal fluid (...

journal_title：NeuroImage. Clinical

authors： Migliaccio R,Agosta F,Basaia S,Cividini C,Habert MO,Kas A,Montembeault M,Filippi M

更新日期：2020-01-01 00:00:00

abstract：:Children and adolescents with congenital heart disease (CHD) are at risk for mild to moderate cognitive impairments. In particular, impaired working memory performance has been found in CHD patients of all ages. Working memory is an important domain of higher order cognitive function and is crucial for everyday activi...

journal_title：NeuroImage. Clinical

authors： Ehrler M,Latal B,Kretschmar O,von Rhein M,O'Gorman Tuura R

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The history of immune suppression, especially CD4 nadir, has been shown to be a strong predictor of HIV-associated neurocognitive disorders (HAND). However, the potential mechanism of this association is not well understood. METHODS:High resolution structural MRI images and neuropsychological data were obta...

journal_title：NeuroImage. Clinical

authors： Hassanzadeh-Behbahani S,Shattuck KF,Bronshteyn M,Dawson M,Diaz M,Kumar P,Moore DJ,Ellis RJ,Jiang X

更新日期：2020-01-01 00:00:00

abstract：:The detection of new or enlarged white-matter lesions is a vital task in the monitoring of patients undergoing disease-modifying treatment for multiple sclerosis. However, the definition of 'new or enlarged' is not fixed, and it is known that lesion-counting is highly subjective, with high degree of inter- and intra-r...

journal_title：NeuroImage. Clinical

authors： McKinley R,Wepfer R,Grunder L,Aschwanden F,Fischer T,Friedli C,Muri R,Rummel C,Verma R,Weisstanner C,Wiestler B,Berger C,Eichinger P,Muhlau M,Reyes M,Salmen A,Chan A,Wiest R,Wagner F

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Predicting cognitive decline and the eventual onset of dementia in patients with Mild Cognitive Impairment (MCI) is of high value for patient management and potential cohort enrichment in pharmaceutical trials. We used cognitive scores and MRI biomarkers from a single baseline visit to predict the onset of d...

journal_title：NeuroImage. Clinical

authors： Zandifar A,Fonov VS,Ducharme S,Belleville S,Collins DL,Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2020-01-01 00:00:00

abstract：:Autism Spectrum Disorder (ASD) is a brain disorder that is typically characterized by deficits in social communication and interaction, as well as restrictive and repetitive behaviors and interests. During the last years, there has been an increase in the use of magnetic resonance imaging (MRI) to help in the detectio...

journal_title：NeuroImage. Clinical

authors： Rakić M,Cabezas M,Kushibar K,Oliver A,Lladó X

更新日期：2020-01-01 00:00:00

abstract：:The locus coeruleus (LC) has a long-established role in the attentional and arousal response to threat, and in the emergence of pathological anxiety in pre-clinical models. However, human evidence of links between LC function and pathological anxiety has been restricted by limitations in discerning LC with current neu...

journal_title：NeuroImage. Clinical

authors： Morris LS,Tan A,Smith DA,Grehl M,Han-Huang K,Naidich TP,Charney DS,Balchandani P,Kundu P,Murrough JW

更新日期：2020-01-01 00:00:00

abstract：:Approximately 30% of adolescents with concussion develop persistent post-concussion symptoms (PPCS) that include emotional symptoms. Elevated amygdalae reactivity to emotional faces has been reported in a variety of psychopathologies characterized by emotional symptoms overlapping with those in PPCS. We tested the hyp...

journal_title：NeuroImage. Clinical

authors： Bohorquez-Montoya L,España LY,Nader AM,Furger RE,Mayer AR,Meier TB

更新日期：2020-01-01 00:00:00

abstract：:Altered resting-state functional connectivity (rsFC) of the amygdala has been demonstrated to be implicated in schizophrenia neuronal pathophysiology. However, whether rsFC of amygdala subregions is differentially affected in schizophrenia remains unclear. This study compared the functional networks of each amygdala s...

journal_title：NeuroImage. Clinical

authors： Zhang M,Yang F,Fan F,Wang Z,Hong X,Tan Y,Tan S,Hong LE

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:Previous imaging studies in patients with refractory temporal lobe epilepsy (TLE) have examined the spatial distribution of changes in imaging parameters such as diffusion tensor imaging (DTI) metrics and cortical thickness. Multi-compartment models offer greater specificity with parameters more directly relate...

journal_title：NeuroImage. Clinical

authors： Winston GP,Vos SB,Caldairou B,Hong SJ,Czech M,Wood TC,Wastling SJ,Barker GJ,Bernhardt BC,Bernasconi N,Duncan JS,Bernasconi A

更新日期：2020-01-01 00:00:00

abstract：:Patients with major depressive disorder (MDD) show heterogeneous treatment response and highly variable clinical trajectories: while some patients experience swift recovery, others show relapsing-remitting or chronic courses. Predicting individual clinical trajectories at an early stage is a key challenge for psychiat...

journal_title：NeuroImage. Clinical

authors： Frässle S,Marquand AF,Schmaal L,Dinga R,Veltman DJ,van der Wee NJA,van Tol MJ,Schöbi D,Penninx BWJH,Stephan KE

更新日期：2020-01-01 00:00:00

abstract：:Gray matter disruptions have been found consistently in Attention-deficit/Hyperactivity Disorder (ADHD). The organization of these alterations into brain structural networks remains largely unexplored. We investigated 508 participants (281 males) with ADHD (N = 210), their unaffected siblings (N = 108), individuals wi...

journal_title：NeuroImage. Clinical

authors： Jiang W,Duan K,Rootes-Murdy K,Hoekstra PJ,Hartman CA,Oosterlaan J,Heslenfeld D,Franke B,Buitelaar J,Arias-Vasquez A,Liu J,Turner JA

更新日期：2020-01-01 00:00:00

abstract：:The perception of faces and consequent social inferences are fundamental for interpersonal communication. While facial expression is important for interindividual communication, constitutional and acquired features are crucial for basic emotions of attraction or repulsion. An emotional bias in face processing has been...

journal_title：NeuroImage. Clinical

authors： Furger S,Stahnke A,Zengaffinen F,Federspiel A,Morishima Y,Papmeyer M,Wiest R,Dierks T,Strik W

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Progressive cognitive decline following multimodal neurooncological treatment is a common observation in patients suffering from malignant glioma. Alterations of the default-mode network (DMN) represent a possible source of impaired neurocognitive functioning and were analyzed in these patients. METHODS:Eig...

journal_title：NeuroImage. Clinical

authors： Kocher M,Jockwitz C,Caspers S,Schreiber J,Farrher E,Stoffels G,Filss C,Lohmann P,Tscherpel C,Ruge MI,Fink GR,Shah NJ,Galldiks N,Langen KJ

更新日期：2020-01-01 00:00:00

abstract：:Visual field defects in chronic hemianopia can improve through visual restitution training, yet not all patients benefit equally from this long and exhaustive procedure. Here, we asked if resting-state functional connectivity prior to visual restitution could predict training success. In two training sessions of eight...

journal_title：NeuroImage. Clinical

authors： Halbertsma HN,Elshout JA,Bergsma DP,Norris DG,Cornelissen FW,van den Berg AV,Haak KV

更新日期：2020-01-01 00:00:00

abstract：:It is difficult to distinguish schizophrenia (SZ), schizoaffective disorder (SAD), and bipolar disorder with psychosis (BPP) as their clinical diagnoses rely on symptoms that overlap. In this paper, we investigate if there is biological evidence to support the symptom-based clinical categories by looking across the th...

journal_title：NeuroImage. Clinical

authors： Du Y,Hao H,Wang S,Pearlson GD,Calhoun VD

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Differentiation between self-produced tactile stimuli and touch by others is necessary for social interactions and for a coherent concept of "self". In attention-deficit-hyperactivity-disorder (ADHD), tactile hypersensitivity and social cognition problems are part of the symptomatology, but pathophysiologi...

journal_title：NeuroImage. Clinical

authors： Boehme R,Frost Karlsson M,Heilig M,Olausson H,Capusan AJ

更新日期：2020-01-01 00:00:00

abstract：:Neurofeedback (NF), a training tool aimed at enhancing neural self-regulation, has been suggested as a complementary treatment option for neuropsychiatric disorders. Despite its potential as a neurobiological intervention directly targeting neural alterations underlying clinical symptoms, the efficacy of NF for the tr...

journal_title：NeuroImage. Clinical

authors： Weber LA,Ethofer T,Ehlis AC

更新日期：2020-01-01 00:00:00

abstract：:Simultaneous real-time fMRI and EEG neurofeedback (rtfMRI-EEG-nf) is an emerging neuromodulation approach, that enables simultaneous volitional regulation of both hemodynamic (BOLD fMRI) and electrophysiological (EEG) brain activities. Here we report the first application of rtfMRI-EEG-nf for emotion self-regulation t...

journal_title：NeuroImage. Clinical

authors： Zotev V,Mayeli A,Misaki M,Bodurka J

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Stuttering is a complex speech fluency disorder occurring in childhood. In young children, stuttering has been associated with speech-related auditory and motor areas of the brain. During transition into adolescence, the majority of children who stutter (75-80%) will experience remission of their symptoms. T...

journal_title：NeuroImage. Clinical

authors： Koenraads SPC,van der Schroeff MP,van Ingen G,Lamballais S,Tiemeier H,Baatenburg de Jong RJ,White T,Franken MC,Muetzel RL

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Premutation carriers of the FMR1 gene are at risk of developing fragile X-associated tremor/ataxia syndrome (FXTAS), a neurodegenerative disease characterized by motor, cognitive, and psychiatric decline as well as cerebellar and cerebral white matter pathology. Several studies have documented preclinical ...

journal_title：NeuroImage. Clinical

authors： McKinney WS,Bartolotti J,Khemani P,Wang JY,Hagerman RJ,Mosconi MW

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Parkinson's disease is associated with severe nigro-striatal dopamine depletion, leading to motor dysfunction and altered reward processing. We previously showed that drug-naïve patients with Parkinson's disease had a consistent attenuation of reward signalling in the mesolimbic and mesocortical system. Here...

journal_title：NeuroImage. Clinical

authors： van der Vegt JPM,Hulme OJ,Madsen KH,Buhmann C,Bloem BR,Münchau A,Helmich RC,Siebner HR

更新日期：2020-01-01 00:00:00

abstract：:The identification of oscillatory neural markers of Parkinson's disease (PD) can contribute not only to the understanding of functional mechanisms of the disorder, but may also serve in adaptive deep brain stimulation (DBS) systems. These systems seek online adaptation of stimulation parameters in closed-loop as a fun...

journal_title：NeuroImage. Clinical

authors： Castaño-Candamil S,Piroth T,Reinacher P,Sajonz B,Coenen VA,Tangermann M

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Successful neurosurgical intervention in gliomas depends on the precision of the preoperative definition of the tumor and its margins since a safe maximum resection translates into a better patient outcome. Metabolic high-resolution imaging might result in improved presurgical tumor characterization, and thu...

journal_title：NeuroImage. Clinical

authors： Hangel G,Cadrien C,Lazen P,Furtner J,Lipka A,Hečková E,Hingerl L,Motyka S,Gruber S,Strasser B,Kiesel B,Mischkulnig M,Preusser M,Roetzer T,Wöhrer A,Widhalm G,Rössler K,Trattnig S,Bogner W

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Insomnia disorder has been reclassified into short-term/acute and chronic subtypes based on recent etiological advances. However, understanding the similarities and differences in the neural mechanisms underlying the two subtypes and accurately predicting the sleep quality remain challenging. METHODS:Using ...

journal_title：NeuroImage. Clinical

authors： Ma X,Wu D,Mai Y,Xu G,Tian J,Jiang G

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:Multiple system atrophy (MSA) is an atypical parkinsonian syndrome and often difficult to discriminate clinically from progressive supranuclear palsy (PSP) and Parkinson's disease (PD) in early stages. Although a characteristic metabolic brain network has been reported for MSA, it is unknown whether this networ...

journal_title：NeuroImage. Clinical

authors： Shen B,Wei S,Ge J,Peng S,Liu F,Li L,Guo S,Wu P,Zuo C,Eidelberg D,Wang J,Ma Y

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:This prospective clinical trial investigated sodium (23Na) MRI at 7 Tesla (T) field strength as biomarker for tumor extent, isocitrate dehydrogenase (IDH) mutation and O6-methylguanine DNA methyltransferase (MGMT) promotor methylation in glioma patients. METHODS:28 glioma patients underwent 23Na MRI on a 7T sc...

journal_title：NeuroImage. Clinical

authors： Regnery S,Behl NGR,Platt T,Weinfurtner N,Windisch P,Deike-Hofmann K,Sahm F,Bendszus M,Debus J,Ladd ME,Schlemmer HP,Rieken S,Adeberg S,Paech D

更新日期：2020-01-01 00:00:00

abstract：:Cerebral Microbleeds (CMBs) are small chronic brain hemorrhages, which have been considered as diagnostic indicators for different cerebrovascular diseases including stroke, dysfunction, dementia, and cognitive impairment. However, automated detection and identification of CMBs in Magnetic Resonance (MR) images is a v...

journal_title：NeuroImage. Clinical

authors： Al-Masni MA,Kim WR,Kim EY,Noh Y,Kim DH

更新日期：2020-01-01 00:00:00

abstract：:Children who have been diagnosed with autism spectrum disorder (ASD) often show a marked deficit in measures of social cognition. In autistic adults, measures of social cognition have been shown to relate to differences in brain synchronization (as measured by fMRI) when individuals are processing naturalistic stimuli...

journal_title：NeuroImage. Clinical

authors： Lyons KM,Stevenson RA,Owen AM,Stojanoski B

更新日期：2020-01-01 00:00:00

abstract：:Disparate diagnostic categories from the Diagnostic and Statistical Manual of Mental Disorders (DSM), including generalized anxiety disorder, major depressive disorder and post-traumatic stress disorder, share common behavioral and phenomenological dysfunctions. While high levels of comorbidity and common features acr...

journal_title：NeuroImage. Clinical

authors： Seok D,Smyk N,Jaskir M,Cook P,Elliott M,Girelli T,Scott JC,Balderston N,Beer J,Stock J,Makhoul W,Gur RC,Davatzikos C,Shinohara R,Sheline Y

更新日期：2020-01-01 00:00:00

abstract：:Autism spectrum disorder (ASD) is characterized by deficits in social interactions, impairments in language and communication, and highly restricted behavioral interests. Transcranial direct current stimulation (tDCS) is a widely used form of noninvasive stimulation and may have therapeutic potential for ASD. So far, ...

journal_title：NeuroImage. Clinical

authors： Zhou T,Kang J,Li Z,Chen H,Li X

更新日期：2020-01-01 00:00:00

abstract：:The intraparietal sulcus (IPS) plays a key role in the distribution of attention across the visual field. In stroke patients, an imbalance between left and right IPS activity has been related to a spatial bias in visual attention characteristic of hemispatial neglect. In this study, we describe the development and imp...

journal_title：NeuroImage. Clinical

authors： Wang T,Peeters R,Mantini D,Gillebert CR

更新日期：2020-01-01 00:00:00

abstract：:Cognitive reasoning is thought to require functional interactions between whole-brain networks. Such networks rely on both cerebral hemispheres, with the corpus callosum providing cross-hemispheric communication. Here we used high-field functional magnetic resonance imaging (7 T fMRI), a well validated cognitive task,...

journal_title：NeuroImage. Clinical

authors： Hearne LJ,Dean RJ,Robinson GA,Richards LJ,Mattingley JB,Cocchi L

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Multiple pathway models of ADHD suggest that multiple, separable biological pathways may lead to symptoms of the disorder. If this is the case, it should be possible to identify subgroups of children with ADHD based on distinct patterns of brain activity. Previous studies have used latent class analysis (LCA...

journal_title：NeuroImage. Clinical

authors： Lecei A,van Hulst BM,de Zeeuw P,van der Pluijm M,Rijks Y,Durston S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Quantitative MRI (qMRI) permits the quantification of brain changes compatible with inflammation, degeneration and repair in multiple sclerosis (MS) patients. In this study, we propose a new method to provide personalized maps of tissue alterations and longitudinal brain changes based on diffe...

journal_title：NeuroImage. Clinical

authors： Bonnier G,Fischi-Gomez E,Roche A,Hilbert T,Kober T,Krueger G,Granziera C

更新日期：2019-01-01 00:00:00