abstract：BACKGROUND:Many individuals with obsessive-compulsive disorder (OCD) do not receive professional treatment due to various idiosyncratic barriers. Internet-based cognitive-behavioral therapy (iCBT) is increasingly used to narrow treatment gaps, but the efficacy of such interventions without guidance of therapists has no...

journal_title：Depression and anxiety

authors： Schröder J,Werkle N,Cludius B,Jelinek L,Moritz S,Westermann S

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Pathological avoidance is a transdiagnostic characteristic of anxiety disorders. Avoidance conditioning re-emerged as a translational model to examine mechanisms and treatment of avoidance. However, its validity for anxiety disorders remains unclear. METHODS:This study tested for altered avoidance in patien...

journal_title：Depression and anxiety

authors： Pittig A,Boschet JM,Glück VM,Schneider K

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Previous work on gene-environment (GxE) interplay concerning anxiety has focused on the interaction of 5-HTTLPR with childhood adversities or traumatic events whereas the impact of recent stressors is understudied, as is the integration of resilience. The current study aimed to investigate the interactive ef...

journal_title：Depression and anxiety

authors： Ollmann TM,Voss C,Venz J,Seidl E,Hoyer J,Kische H,Pieper L,Schiele MA,Domschke K,Beesdo-Baum K

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Although trauma-focused cognitive behavioral therapy (TF-CBT) is the frontline treatment for posttraumatic stress disorder (PTSD), at least one-third of patients are treatment nonresponders. This study aimed to identify neural markers of treatment response, specifically the prediction of remission of specifi...

journal_title：Depression and anxiety

authors： Bryant RA,Erlinger M,Felmingham K,Malhi GS,O'Donnell ML,Williams LM,Korgaonkar MS

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Anxiety symptoms are common in adolescence and are often considered developmentally benign. Yet for some, anxiety presents with serious comorbid nonanxiety psychopathology. Early identification of such "malignant" anxiety presentations is a major challenge. We aimed to characterize anxiety symptoms suggestiv...

journal_title：Depression and anxiety

authors： Barzilay R,White LK,Moore TM,Calkins ME,Taylor JH,Patrick A,Huque ZM,Young JF,Ruparel K,Pine DS,Gur RC,Gur RE

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Psychiatrists frequently struggle with how to sequence treatment for depressed adolescents who do not respond to an adequate trial of a selective serotonin reuptake inhibitor (SSRI). This study leveraged recent statistical and computational advances to create Bayesian hierarchal models (BHMs) of response in ...

journal_title：Depression and anxiety

authors： Suresh V,Mills JA,Croarkin PE,Strawn JR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The link between systemic inflammation and depression has been deeply investigated, but relatively few studies explored symptom-specific associations, mostly focusing on common inflammatory biomarkers like C-reactive protein (CRP) levels. METHODS:We investigated associations of low-grade inflammation with d...

journal_title：Depression and anxiety

authors： Gialluisi A,Di Castelnuovo A,Bracone F,De Curtis A,Cerletti C,Donati MB,de Gaetano G,Iacoviello L

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:To explore the anxiolytic effects of a 4-month randomized, placebo-controlled trial of exercise and antidepressant medication in patients with major depressive disorder (MDD), and to examine the potential modifying effects of anxiety in treating depressive symptoms. MATERIALS AND METHODS:In this secondary a...

journal_title：Depression and anxiety

authors： Blumenthal JA,Babyak MA,Craighead WE,Davidson J,Hinderliter A,Hoffman B,Doraiswamy PM,Sherwood A

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Many patients with major depressive disorder (MDD) have been found to have psychotic symptoms. However, few studies have reported the prevalence of comorbid psychotic symptoms in first-episode drug naïve (FEDN) MDD patients. This study was to investigate the prevalence of psychotic symptoms and related risk ...

journal_title：Depression and anxiety

authors： Shen Y,Wei Y,Yang XN,Zhang G,Du X,Jia Q,Zhu X,Ma Y,Lang X,Luo X,Zhang XY

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Individuals with depression may not seek treatment for their symptoms due to several types of barriers to treatment. In support of the growing research on mental health care access and the role of social media, this study aimed to increase knowledge of these barriers among social media users. METHODS:Partic...

journal_title：Depression and anxiety

authors： Szlyk H,Deng J,Xu C,Krauss MJ,Cavazos-Rehg PA

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Chronotype is an individual's preferred timing of sleep and activity, and is often referred to as a later chronotype (or evening-type) or an earlier chronotype (or morning-type). Having an evening chronotype is associated with more severe depressive and anxiety symptoms. Based on these findings it is has bee...

journal_title：Depression and anxiety

authors： Druiven SJM,Hovenkamp-Hermelink JHM,Knapen SE,Kamphuis J,Haarman BCM,Penninx BWJH,Antypa N,Meesters Y,Schoevers RA,Riese H

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Although evidence-based psychotherapies (EBPs) for posttraumatic stress disorder (PTSD) were implemented starting in 2005 in the veterans health administration (VHA), the largest national healthcare system in the U.S., the rate of initiation (uptake) and prevalence of these treatments in each calendar year h...

journal_title：Depression and anxiety

authors： Maguen S,Holder N,Madden E,Li Y,Seal KH,Neylan TC,Lujan C,Patterson OV,DuVall SL,Shiner B

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Physical activity is increasingly recognized as an important modifiable factor for depression. However, the extent to which individuals with stable risk factors for depression, such as high genetic vulnerability, can benefit from the protective effects of physical activity, remains unknown. Using a longitudi...

journal_title：Depression and anxiety

authors： Choi KW,Zheutlin AB,Karlson RA,Wang MJ,Dunn EC,Stein MB,Karlson EW,Smoller JW

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Complicated grief (CG) is a bereavement-specific syndrome distinct from but commonly comorbid with posttraumatic stress disorder (PTSD). While bereavement is common among military personnel (Simon et al., 2018), there is little research on the impact of CG comorbidity on PTSD treatment outcomes. METHODS:To ...

journal_title：Depression and anxiety

authors： Simon NM,Hoeppner SS,Lubin RE,Robinaugh DJ,Malgaroli M,Norman SB,Acierno R,Goetter EM,Hellberg SN,Charney ME,Bui E,Baker AW,Smith E,Kim HM,Rauch SAM

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Social anxiety disorder (SAD) is an incapacitating disorder running in families. Previous work associated social fearfulness with a failure to habituate, but the habituation response to neutral faces has, as of yet, not been investigated in patients with SAD and their family members concurrently. Here, we ex...

journal_title：Depression and anxiety

authors： Bas-Hoogendam JM,van Steenbergen H,Blackford JU,Tissier RLM,van der Wee NJA,Westenberg PM

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Actigraphy may provide a more valid assessment of sleep, circadian rhythm (CR), and physical activity (PA) than self-reported questionnaires, but has not been used widely to study the association with depression/anxiety and their clinical characteristics. METHODS:Fourteen-day actigraphy data of 359 particip...

journal_title：Depression and anxiety

authors： Difrancesco S,Lamers F,Riese H,Merikangas KR,Beekman ATF,van Hemert AM,Schoevers RA,Penninx BWJH

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To examine (1) clinically relevant anxiety with comorbid depression in an older population, and the presentation of subthreshold symptoms; (2) to assess anxiety and levels of comorbid depression associated with migration, religion, loneliness and long-term illness. METHODS:Analysis of Wave 1 of The Irish Lon...

journal_title：Depression and anxiety

authors： Curran E,Rosato M,Cooper J,Mc Garrigle CA,Leavey G

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Fear overgeneralization is a central feature of anxiety disorders and can lead to excessive avoidance. As perceptual discrimination is a key component of fear overgeneralization, a perceptual discrimination training task was created aimed at improving perceptual discrimination and reducing fear overgeneraliz...

journal_title：Depression and anxiety

authors： Ginat-Frolich R,Klein Z,Aderka IM,Shechner T

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Recent evidence shows that screen time may be an important risk factor for mental health. The aim of this study was to examine the association of computer/mobile devices (CMD) use and TV watching separately with depressive symptoms in a large representative sample of Chinese adults. METHODS:A sample of 18,9...

journal_title：Depression and anxiety

authors： Yu B,Gu Y,Bao X,Meng G,Wu H,Zhang Q,Liu L,Sun S,Wang X,Zhou M,Jia Q,Song K,Niu K

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Despite its popularity, little is known about the measurement invariance of the Patient Health Questionnaire-9 (PHQ-9) across U.S. sociodemographic groups. Use of a screener shown not to possess measurement invariance could result in under/over-detection of depression, potentially exacerbating sociodemograph...

journal_title：Depression and anxiety

authors： Patel JS,Oh Y,Rand KL,Wu W,Cyders MA,Kroenke K,Stewart JC

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:The significance of the timing and chronicity of childhood adversity for depression outcomes later in life is unclear. Identifying trajectories of adversity throughout childhood would allow classification of children according to the accumulation, timing, and persistence of adversity, and may provide unique ...

journal_title：Depression and anxiety

authors： Tracy M,Salo M,Slopen N,Udo T,Appleton AA

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Evidence-based treatments for post-traumatic stress disorder (PTSD) have poor uptake and remission rates, suggesting that alternative treatments are needed. Morning bright light may be an effective treatment for PTSD given its established effects on mood and sleep, however, there are no published trials. ME...

journal_title：Depression and anxiety

authors： Zalta AK,Bravo K,Valdespino-Hayden Z,Pollack MH,Burgess HJ

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Parental mental disorders have been shown to predict offspring's mental health problems. We examined whether pathways from parental mental disorders to offspring's psychiatric work disability in early adulthood are mediated through offspring's mental disorders and social disadvantage in adolescence. METHODS...

journal_title：Depression and anxiety

authors： Halonen JI,Merikukka M,Gissler M,Kerkelä M,Virtanen M,Ristikari T,Hiilamo H,Lallukka T

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Synchronized transcranial magnetic stimulation (sTMS) is a new modality to reduce symptoms of major depressive disorder (MDD). sTMS uses rotating neodymium magnets to deliver low-field stimulation matched to the individual alpha frequency (IAF). A previous multisite study showed that sTMS significantly reduc...

journal_title：Depression and anxiety

authors： Philip NS,Leuchter AF,Cook IA,Massaro J,Goethe JW,Carpenter LL

更新日期：2019-03-01 00:00:00

abstract：:Despite emotion regulation being altered in patients with obsessive-compulsive disorder (OCD), no studies have investigated its relation to multimodal amygdala connectivity. We compared corticolimbic functional and structural connectivity between OCD patients and healthy controls (HCs), and correlated this with the di...

journal_title：Depression and anxiety

authors： Picó-Pérez M,Ipser J,Taylor P,Alonso P,López-Solà C,Real E,Segalàs C,Roos A,Menchón JM,Stein DJ,Soriano-Mas C

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Despite the effectiveness of evidence-based treatments for posttraumatic stress disorder (PTSD), some symptoms, such as sleep disturbance, can be difficult to treat regardless of treatment type. METHODS:We examined residual PTSD symptoms in 235 female veterans and soldiers who were randomized to receive 10 ...

journal_title：Depression and anxiety

authors： Schnurr PP,Lunney CA

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Prevention of PTSD requires identification of subpopulations contributing most to the population burden of PTSD. This study examines the relative contribution of subthreshold PTSD and probable PTSD on future PTSD in a representative military cohort. METHODS:We analyze data on 3,457 U.S. National Guard membe...

journal_title：Depression and anxiety

authors： Fink DS,Gradus JL,Keyes KM,Calabrese JR,Liberzon I,Tamburrino MB,Cohen GH,Sampson L,Galea S

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Recent research suggests that posttraumatic stress disorder (PTSD) is associated with altered amygdala and hippocampal resting-state functional connectivity (rsFC). However, less research has examined whether Prolonged Exposure (PE), a first line exposure-based treatment for PTSD, has the potential to alter ...

journal_title：Depression and anxiety

authors： Zhu X,Suarez-Jimenez B,Lazarov A,Helpman L,Papini S,Lowell A,Durosky A,Lindquist MA,Markowitz JC,Schneier F,Wager TD,Neria Y

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Television (TV) viewing and computer use have been associated with higher risk of depression, but studies specifically assessing the impact of these and other types of sedentary behaviors (SBs) on the mental health of older adults are scarce and their results are inconclusive. Similarly, the association betw...

journal_title：Depression and anxiety

authors： Andrade-Gómez E,Martínez-Gómez D,Rodríguez-Artalejo F,García-Esquinas E

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Adolescent depression may increase risk for poor mental health outcomes in adulthood. The objective of this study was to systematically review the literature on the association between adolescent depression and adult anxiety and depressive disorders as well as suicidality. METHODS:EMBASE, MEDLINE, and PSYCi...

journal_title：Depression and anxiety

authors： Johnson D,Dupuis G,Piche J,Clayborne Z,Colman I

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Socioeconomic deprivation is associated with higher prevalence of mental health problems; however, the influence of socioeconomic status (SES) on psychological therapy outcomes is as yet unclear. AIM:To review published evidence on the association between indicators of SES (income, education, employment, ne...

journal_title：Depression and anxiety

authors： Finegan M,Firth N,Wojnarowski C,Delgadillo J

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:To elucidate mechanisms related to remission in winter seasonal affective disorder (SAD), we explored the course of individual depressive symptom offset across two distinct treatment modalities that show comparable outcomes at treatment endpoint: cognitive-behavioral therapy for SAD (CBT-SAD) and light thera...

journal_title：Depression and anxiety

authors： Meyerhoff J,Young MA,Rohan KJ

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Although there has been abundant research on chronic low-grade inflammation as a potential mechanism underlying the link between mood disorders and cardiovascular risk, less is known about the role of inflammatory factors and anxiety disorders. The aim of this paper is to evaluate the bi-directional associat...

journal_title：Depression and anxiety

authors： Glaus J,von Känel R,Lasserre AM,Strippoli MF,Vandeleur CL,Castelao E,Gholam-Rezaee M,Marangoni C,Wagner EN,Marques-Vidal P,Waeber G,Vollenweider P,Preisig M,Merikangas KR

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:An issue of critical importance for psychiatry and women's health is whether postpartum depression (PPD) represents a unique condition. The Diagnostic and Statistical Manual of Mental Disorders asserts that major depressive disorder (MDD) may present with peripartum onset, without suggesting any other differ...

journal_title：Depression and anxiety

authors： Fox M,Sandman CA,Davis EP,Glynn LM

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Prenatal maternal depression has been associated with multiple problems in offspring involving affect, cognition, and neuroendocrine functioning. This suggests that prenatal depression influences neurodevelopment. However, the underlying neurodevelopmental mechanism remains unclear. We prospectively assessed...

journal_title：Depression and anxiety

authors： El Marroun H,Zou R,Muetzel RL,Jaddoe VW,Verhulst FC,White T,Tiemeier H

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:The role of the neuropeptide oxytocin (OT) in Borderline Personality Disorder (BPD) is poorly understood. It is particularly unknown how early experiences with caregivers moderate the action of OT in BPD. Here, we examined the association of plasma OT levels in BPD patients with the experience of c...

journal_title：Depression and anxiety

authors： Ebert A,Edel MA,Gilbert P,Brüne M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:To examine the potential mediating role of parenting behaviors in the longitudinal, bidirectional relationships between maternal depression and child internalizing symptoms (i.e. depression and anxiety). METHODS:We analyzed data from 4,581 mother-child dyads from the Fragile Families and Child Wellbeing Stu...

journal_title：Depression and anxiety

authors： Kuckertz JM,Mitchell C,Wiggins JL

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The past decade of research has seen considerable interest in computer-based approaches designed to directly target cognitive mechanisms of anxiety, such as attention bias modification (ABM). METHODS:By pooling patient-level datasets from randomized controlled trials of ABM that utilized a dot-probe trainin...

journal_title：Depression and anxiety

authors： Price RB,Kuckertz JM,Amir N,Bar-Haim Y,Carlbring P,Wallace ML

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Patients with obsessive-compulsive disorder (OCD) experience abnormally high levels of uncertainty, and unpredictability is evaluated negatively and not well tolerated. The current study examined neural correlates of attentional processing in response to experimentally induced uncertainty in OCD. METHODS:Tw...

journal_title：Depression and anxiety

authors： Dieterich R,Endrass T,Kathmann N

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Exposure and response prevention (ERP) is an effective treatment for individuals with obsessive-compulsive disorder (OCD), yet a substantial number of individuals with OCD do not fully respond to this intervention. Based on emerging experimental and clinical research on acceptance, this study sought to explor...

journal_title：Depression and anxiety

authors： Reid AM,Garner LE,Van Kirk N,Gironda C,Krompinger JW,Brennan BP,Mathes BM,Monaghan SC,Tifft ED,André MC,Cattie J,Crosby JM,Elias JA

更新日期：2017-11-01 00:00:00