Subthreshold PTSD and PTSD in a prospective-longitudinal cohort of military personnel: Potential targets for preventive interventions.

abstract：:The use of a placebo run-in phase, in which placebo responders are withdrawn from a study before random assignment to treatment condition, has been criticized as favoring the active treatment in clinical trials. We compared the effect size of randomized, placebo-controlled clinical trials (in the treatment of depressi...

journal_title：Depression and anxiety

authors： Lee S,Walker JR,Jakul L,Sexton K

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Vilazodone, a selective serotonin reuptake inhibitor and 5-HT1A receptor partial agonist, is approved for treating major depressive disorder in adults. This study (NCT01629966 ClinicalTrials.gov) evaluated the efficacy and safety of vilazodone in adults with generalized anxiety disorder (GAD). METHODS:A mul...

journal_title：Depression and anxiety

authors： Gommoll C,Durgam S,Mathews M,Forero G,Nunez R,Tang X,Thase ME

更新日期：2015-06-01 00:00:00

abstract：:This paper discusses the role of psychosocial intervention in the treatment of suicidal youth, summarizes the existing relevant literature, describes model programs for treating suicidal youth, and discusses efficacy-to-effectiveness issues in working with this population. ...

journal_title：Depression and anxiety

authors： Fristad MA,Shaver AE

更新日期：2001-01-01 00:00:00

abstract：:This study seeks to determine how panic disorder patients with anxiety and depression comorbidity differ from panic disorder patients without comorbidity at the time of presentation for treatment. One-hundred seventy-one panic disorder patients presenting for their initial assessment and treatment at the Payne Whitney...

journal_title：Depression and anxiety

authors： Apfeldorf WJ,Spielman LA,Cloitre M,Heckelman L,Shear MK

更新日期：2000-01-01 00:00:00

abstract：:This study assessed striatal dopamine 1 (D1) receptor binding in patients with major depressive disorder and anger attacks (MDD+A) and healthy volunteers. We used positron emission tomography with [(11)C]SCH 23,390 to compare 10 patients with MDD+A to 10 healthy volunteers. [(11)C]SCH 23,390 binding in bilateral stria...

journal_title：Depression and anxiety

authors： Dougherty DD,Bonab AA,Ottowitz WE,Livni E,Alpert NM,Rauch SL,Fava M,Fischman AJ

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Socioeconomic deprivation is associated with higher prevalence of mental health problems; however, the influence of socioeconomic status (SES) on psychological therapy outcomes is as yet unclear. AIM:To review published evidence on the association between indicators of SES (income, education, employment, ne...

journal_title：Depression and anxiety

authors： Finegan M,Firth N,Wojnarowski C,Delgadillo J

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:There is ample evidence of the efficacy of cognitive-behavioral therapy (CBT) for depression in adolescents, including Puerto Rican adolescents. However, there is still a high percentage of adolescents who do not respond to a standard "dose" of 12 sessions of CBT. This clinical case study explores the charac...

journal_title：Depression and anxiety

authors： Jiménez Chafey MI,Bernal G,Rosselló J

更新日期：2009-01-01 00:00:00

abstract：:There are no reports of a child taking a selective serotonin reuptake inhibitor and an atypical anti-psychotic being successfully tapered from these medications after completion of cognitive-behavioral therapy (CBT) for obsessive-compulsive disorder. With this in mind, we report the case of an 8.5-year-old male who wa...

journal_title：Depression and anxiety

authors： Goldstein RB,Storch EA,Lehmkuhl H,Geffken GR,Goodman WK,Murphy TK

更新日期：2009-01-01 00:00:00

abstract：:Despite emotion regulation being altered in patients with obsessive-compulsive disorder (OCD), no studies have investigated its relation to multimodal amygdala connectivity. We compared corticolimbic functional and structural connectivity between OCD patients and healthy controls (HCs), and correlated this with the di...

journal_title：Depression and anxiety

authors： Picó-Pérez M,Ipser J,Taylor P,Alonso P,López-Solà C,Real E,Segalàs C,Roos A,Menchón JM,Stein DJ,Soriano-Mas C

更新日期：2019-02-01 00:00:00

abstract：:The goal of this study was to discriminate subtypes of pediatric obsessive-compulsive disorder (OCD) among youth with and without a comorbid tic disorder. Seventy-four youth (M(age)=9.7+/-2.3 years) with a principal diagnosis of OCD, with (n=46) or without (n=28) a comorbid tic disorder, were assessed with a semi-stru...

journal_title：Depression and anxiety

authors： Storch EA,Stigge-Kaufman D,Marien WE,Sajid M,Jacob ML,Geffken GR,Goodman WK,Murphy TK

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:There is a growing body of literature suggesting that panic attacks without panic disorder are associated with increases in a wide range of psychopathology and impairment. However, the majority of the literature to date has been cross-sectional. Some longitudinal research supports the view that panic attacks...

journal_title：Depression and anxiety

authors： Kinley DJ,Walker JR,Enns MW,Sareen J

更新日期：2011-05-01 00:00:00

abstract：:This study explores the psychometric properties of the Portuguese version of Corah's Dental Anxiety Scale (DAS), an instrument designed to assess the manifestations of dental anxiety. The DAS has been translated into several languages, but no adaptation and reliability analysis of the Portuguese version of the scale h...

journal_title：Depression and anxiety

authors： Hu LW,Gorenstein C,Fuentes D

更新日期：2007-01-01 00:00:00

abstract：:This study examined the differences of heart rate variability measures between children of parents with panic disorder and children of healthy controls using linear as well as nonlinear techniques. Supine and standing heart rate variability indices were measured in all children using power spectral analysis and a meas...

journal_title：Depression and anxiety

authors： Srinivasan K,Ashok MV,Vaz M,Yeragani VK

更新日期：2002-01-01 00:00:00

abstract：:The diagnosis of anxiety disorders and major depression can be reliably made based on signs and symptoms. However there are significant limitations to the current system of classification including overlapping criteria, high comorbidity, and the issue of subthreshold syndromes. The literature on treatment response doc...

journal_title：Depression and anxiety

authors： Ninan PT,Berger J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Exaggerated amygdala activation to threatening faces has been detected in adults and children with anxiety disorders, compared to healthy comparison (HC) subjects. However, the profile of amygdala activation in response to facial expressions in obsessive-compulsive disorder (OCD) may be a distinguishing feat...

journal_title：Depression and anxiety

authors： Britton JC,Stewart SE,Killgore WD,Rosso IM,Price LM,Gold AL,Pine DS,Wilhelm S,Jenike MA,Rauch SL

更新日期：2010-07-01 00:00:00

abstract：:Ninety-three patients, including 47 patients with Generalized Anxiety Disorder (GAD) and 46 patients with Major Depression (MD), were entered into recent clinical trials. Clinicians acknowledge that during the initial screening process, clear separation between depressed and anxious patients may be difficult. By using...

journal_title：Depression and anxiety

authors： Freeman AM 3rd,Kablinger AS,Rolland PD,Brannon GE

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Little is known regarding changes in the hypothalamic-pituitary-adrenal axis (HPA axis) of adolescent girls with and without posttraumatic stress disorder (PTSD) who have recently experienced sexual abuse. Therefore, in this pilot study, we utilized non-stressed home saliva collection three times a day for t...

journal_title：Depression and anxiety

authors： Keeshin BR,Strawn JR,Out D,Granger DA,Putnam FW

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Internet-delivered cognitive behavioral therapy (iCBT) is a relatively novel treatment method that may improve the accessibility of mental health care for individuals with posttraumatic stress disorder (PTSD). The aim of this meta-analysis was to evaluate the effectiveness of iCBT compared to inactive (waitl...

journal_title：Depression and anxiety

authors： Sijbrandij M,Kunovski I,Cuijpers P

更新日期：2016-09-01 00:00:00

abstract：:Internet-delivered cognitive behavioral therapy (iCBT) was developed to overcome some of the barriers in accessing best practice face-to-face CBT. iCBT affords many benefits, such as high fidelity, greater accessibility, convenience, and reduced cost to patients and health-care systems. Recent meta-analyses of iCBT fo...

journal_title：Depression and anxiety

authors： Andrews G,Williams AD

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Self-esteem is a major concern in mood disorders. Low self-esteem is a symptom of depressive disorders and is considered by some to be a predictor for relapse, whereas high self-esteem seems to buffer against depression. Recently, Competitive Memory Training (COMET) has shown to be effective for the enhancem...

journal_title：Depression and anxiety

authors： Korrelboom K,Maarsingh M,Huijbrechts I

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Collectively, functional neuroimaging studies implicate frontal-limbic dysfunction in the pathophysiology of posttraumatic stress disorder (PTSD), as reflected by altered amygdala reactivity and deficient prefrontal responses. These neural patterns are often elicited by social signals of threat (fearful/angr...

journal_title：Depression and anxiety

authors： Rabinak CA,MacNamara A,Kennedy AE,Angstadt M,Stein MB,Liberzon I,Phan KL

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The clinical presentation of panic disorder (PD) is known to be highly heterogeneous, complicating research on its etiology, neurobiological pathways, and treatment. None of the attempts to identify PD subtypes have been independently reproduced, rendering the current literature inconclusive. METHODS:Using ...

journal_title：Depression and anxiety

authors： Pattyn T,Van Den Eede F,Lamers F,Veltman D,Sabbe BG,Penninx BW

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Many individuals with obsessive-compulsive disorder (OCD) do not receive professional treatment due to various idiosyncratic barriers. Internet-based cognitive-behavioral therapy (iCBT) is increasingly used to narrow treatment gaps, but the efficacy of such interventions without guidance of therapists has no...

journal_title：Depression and anxiety

authors： Schröder J,Werkle N,Cludius B,Jelinek L,Moritz S,Westermann S

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:We used a dot-probe paradigm to examine attention bias toward threat (i.e., angry) and happy face stimuli in severe mood dysregulation (SMD) versus healthy comparison (HC) youth. The tendency to allocate attention to threat is well established in anxiety and other disorders of negative affect. SMD is charact...

journal_title：Depression and anxiety

authors： Hommer RE,Meyer A,Stoddard J,Connolly ME,Mogg K,Bradley BP,Pine DS,Leibenluft E,Brotman MA

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Metacognitive therapy (MCT) is a relatively new approach to treating mental disorders. The aim of the current meta-analysis was to examine the efficacy of MCT in patients with mental disorders. METHOD:A comprehensive literature search revealed 16 published as well as unpublished studies on the efficacy of M...

journal_title：Depression and anxiety

authors： Normann N,van Emmerik AA,Morina N

更新日期：2014-05-01 00:00:00

abstract：:Sleep deprivation for one night has been investigated as a treatment for depression since the first publications describing its antidepressant properties almost 30 years ago [Pflug and Tolle, 1971: Int Pharmacopsychiatry 6:187-196]. It remains a field of active research. It is the only intervention consistently demons...

journal_title：Depression and anxiety

authors： Ringel BL,Szuba MP

更新日期：2001-01-01 00:00:00

abstract：:Social support is proposed to attenuate behavioral consequences of exposure to uncontrollable stressors. To test this possibility, we compared the effects of two post-stress housing conditions, in pairs or in groups of 10-12 animals per cage, on the behavior of rats tested in the elevated plus-maze (EPM) 24 hr after s...

journal_title：Depression and anxiety

authors： Andrade CS,Guimarães FS

更新日期：2003-01-01 00:00:00

abstract：:This study was designed to investigate the efficacy of the antidepressant fluvoxamine in the treatment of combat-related post-traumatic stress disorder (PTSD). Fifteen veterans with combat-related PTSD and no other psychiatric diagnosis except depression were recruited to participate in a 14-week open-label study of f...

journal_title：Depression and anxiety

authors： Escalona R,Canive JM,Calais LA,Davidson JR

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The present trial was designed to assess the efficacy and safety of escitalopram prescribed to patients seeking treatment of major depressive disorder (MDD) in a Canadian primary-care setting. METHODS:Investigators (mainly primary-care physicians) enrolled patients with MDD from their daily practice. Patien...

journal_title：Depression and anxiety

authors： Chokka P,Legault M

更新日期：2008-01-01 00:00:00

abstract：:The objective was to present naturalistic 1-year follow-up information of 96 child and adolescent outpatients with major depressive disorder who had been randomized in an 8-week double-blind, placebo-controlled trial of fluoxetine. Subjects were children and adolescents, ages 8-18 years, who were entered in a randomiz...

journal_title：Depression and anxiety

authors： Emslie GJ,Rush AJ,Weinberg WA,Kowatch RA,Carmody T,Mayes TL

更新日期：1998-01-01 00:00:00