Abstract:
:The diagnosis of anxiety disorders and major depression can be reliably made based on signs and symptoms. However there are significant limitations to the current system of classification including overlapping criteria, high comorbidity, and the issue of subthreshold syndromes. The literature on treatment response documents that selective serotonin reuptake inhibitors are effective in the treatment of the various anxiety disorders, including when comorbid major depression is present. The literature also suggests that tricyclic antidepressant medications have superior benefits over selective serotonin reuptake inhibitors in major depression. Examination of the functional anatomy of the fear and reward systems may shed light on the underlying processes in the anxiety and depressive disorders. Such an approach points out the importance of addressing avoidance behaviors, which may be more responsive to cognitive behavioral treatments than pharmacological agents.
journal_name
Depress Anxietyjournal_title
Depression and anxietyauthors
Ninan PT,Berger Jdoi
10.1002/da.1049subject
Has Abstractpub_date
2001-01-01 00:00:00pages
79-85issue
2eissn
1091-4269issn
1520-6394pii
10.1002/da.1049journal_volume
14pub_type
杂志文章,评审abstract:BACKGROUND:Physical activity is increasingly recognized as an important modifiable factor for depression. However, the extent to which individuals with stable risk factors for depression, such as high genetic vulnerability, can benefit from the protective effects of physical activity, remains unknown. Using a longitudi...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22967
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Little is known regarding changes in the hypothalamic-pituitary-adrenal axis (HPA axis) of adolescent girls with and without posttraumatic stress disorder (PTSD) who have recently experienced sexual abuse. Therefore, in this pilot study, we utilized non-stressed home saliva collection three times a day for t...
journal_title:Depression and anxiety
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abstract::This study aimed to assess the effects of anisomycin, a protein synthesis inhibitor, on behavioral responses, brain-derived neurotrophic factor (BDNF) and TrkB mRNA levels, and circulating corticosterone in rats-when administered before or after initial exposure to a predator scent stress stimulus. Magnitude of change...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20366
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abstract::Acute grief is emotionally intense, cognitively preoccupying, and disruptive, but grief is not an illness; major depression and anxiety disorders are. Grief and mourning have a purpose. They provide an intense, focused opportunity to reregulate emotion and to engage in a learning process that is aimed at reconfiguring...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.21963
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:To elucidate mechanisms related to remission in winter seasonal affective disorder (SAD), we explored the course of individual depressive symptom offset across two distinct treatment modalities that show comparable outcomes at treatment endpoint: cognitive-behavioral therapy for SAD (CBT-SAD) and light thera...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.22739
更新日期:2018-05-01 00:00:00
abstract::It is well known that insomnia is more frequent in women than in men throughout all age groups. In this respect insomnia resembles other psychiatric disorders that occur more frequently in women such as anxiety and depressive disorders. Since insomnia is frequently a symptom of anxiety and depression, it remains an op...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.10101
更新日期:2003-01-01 00:00:00
abstract::Pediatric psychopharmacology is hindered by the relative lack of controlled, empirical clinical trials [Shatzberg and Nemeroff, 1998: Washington, D.C.: The American Psychiatric Press, Inc. p 301-306]. Psychiatric disorders in children and adolescents carry considerable morbidity, impede development, and carry a signif...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/1520-6394(2000)12:1+<85::AID-DA12>3.0.CO;2
更新日期:2000-01-01 00:00:00
abstract::Reports on the severity and reversibility of cognitive disturbances in major depression in the literature diverge due to methodological biases. The present study, using a precise methodology, examined attention and executive functions in 20 relatively young, depressed patients presenting a first or second episode of u...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20060
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Whether psychological resilience correlates with neurocognitive performance is largely unknown. Therefore, we assessed association between neurocognitive performance and resilience in individuals with a history of childhood abuse or trauma exposure. METHODS:In this cross-sectional study of 226 highly trauma...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20675
更新日期:2010-08-01 00:00:00
abstract::A National Institutes of Health (National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute on Aging) working group meeting focused on the non-motor aspects of Parkinson's disease (PD). Below is the summary of the meeting presentations and recommendations for a res...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.10057
更新日期:2002-01-01 00:00:00
abstract::Despite emotion regulation being altered in patients with obsessive-compulsive disorder (OCD), no studies have investigated its relation to multimodal amygdala connectivity. We compared corticolimbic functional and structural connectivity between OCD patients and healthy controls (HCs), and correlated this with the di...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22845
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Television (TV) viewing and computer use have been associated with higher risk of depression, but studies specifically assessing the impact of these and other types of sedentary behaviors (SBs) on the mental health of older adults are scarce and their results are inconclusive. Similarly, the association betw...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22804
更新日期:2018-09-01 00:00:00
abstract::Because of their high comorbidity and strong associations, the distinctiveness of anxiety and depression in youth continues to be debated. In this study we used cluster analysis in a community sample (n=225) of youth to test tripartite model predictions regarding the grouping of individuals based on their levels of an...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20215
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Exposure therapy, a gold-standard treatment for anxiety disorders, is assumed to work via extinction learning, but this has never been tested. Anxious individuals demonstrate extinction learning deficits, likely related to less ventromedial prefrontal cortex (vmPFC) and more amygdala activation, but the rela...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22583
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Diagnostic criteria for DSM-5 posttraumatic stress disorder (PTSD) are in many ways similar to DSM-IV criteria, raising the possibility that it might be possible to closely approximate DSM-5 diagnoses using DSM-IV symptoms. If so, the resulting transformation rules could be used to pool research data based o...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22364
更新日期:2015-07-01 00:00:00
abstract::This report describes the reactivation of a posttraumatic stress disorder (PTSD) after a minor head injury in two young women who had recovered from extreme stress caused by sexual abuse during adolescence. Intrusive thoughts, images, dreams, and phobic avoidance bear a direct relationship to the specific circumstance...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/(sici)1520-6394(1998)8:1<43::aid-da9>3.0.c
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Previous studies have indicated a high prevalence of generalized anxiety disorder (GAD) in women with anorexia nervosa (AN). However, the shared genetic and environmental components of these disorders have not been explored. This study seeks to elucidate the shared genetic and environmental components betwee...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20834
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVE:To examine (1) clinically relevant anxiety with comorbid depression in an older population, and the presentation of subthreshold symptoms; (2) to assess anxiety and levels of comorbid depression associated with migration, religion, loneliness and long-term illness. METHODS:Analysis of Wave 1 of The Irish Lon...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22893
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:A pooled analysis was performed on data from two studies evaluating the efficacy of once-daily extended-release quetiapine fumarate (quetiapine XR) monotherapy for patients with major depressive disorder. Through these analyses (based on Hamilton Rating Scale for Depression (HAM-D) and Hamilton Rating Scale ...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.21970
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Current neurobiological models of obsessive-compulsive disorder (OCD) propose a dysfunction of cortico-striato-thalamo-cortical circuits that leads to enhanced activity in frontal and striatal brain regions. In accordance with that, OCD patients show alterations in learning and flexible adaptation to changin...
journal_title:Depression and anxiety
pub_type: 杂志文章
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journal_title:Depression and anxiety
pub_type: 杂志文章
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更新日期:2010-03-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章,meta分析
doi:10.1002/da.10134
更新日期:2004-01-01 00:00:00
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journal_title:Depression and anxiety
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更新日期:2020-05-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20710
更新日期:2010-10-01 00:00:00
abstract::This study seeks to determine how panic disorder patients with anxiety and depression comorbidity differ from panic disorder patients without comorbidity at the time of presentation for treatment. One-hundred seventy-one panic disorder patients presenting for their initial assessment and treatment at the Payne Whitney...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/1520-6394(2000)12:2<78::AID-DA3>3.0.CO;2-5
更新日期:2000-01-01 00:00:00
abstract::Although global clinical rating scales have been a mainstay of clinical research, little is known about the relationship between these measures and other assessment modalities. The present study examined the Clinician's Severity Rating (CSR) from the Anxiety Disorders Interview Schedule in a sample of 186 social phobi...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/(SICI)1520-6394(1996)4:3<120::AID-DA4>3.0.
更新日期:1996-01-01 00:00:00
abstract::Since the introduction of the concept of social anxiety (or phobia) to the American nosological system in DSM-III (1980), it has become increasingly apparent that the condition is also prevalent in other cultures. In Japan, for example, the condition, called taijinkyofusho (usually abbreviated as TKS in English), is w...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/(sici)1520-6394(1997)5:3<115::aid-da1>3.0.
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Investigations of gene-environment interaction (GxE) in depression have implicated a polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) as a moderator of the stress-depression relationship. However, recent evidence for 5-HTTLPR GxE in depression has been inconsistent. This study...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20715
更新日期:2010-08-01 00:00:00
abstract:OBJECTIVE:The impact of childhood adversity persists across the life course. This study aimed to investigate the associations of childhood adversity with the course, suicidality, and treatment outcomes of depressive disorders. METHOD:A total of 919 people with depressive disorders were recruited. Childhood adversities...
journal_title:Depression and anxiety
pub_type: 杂志文章
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更新日期:2013-10-01 00:00:00
abstract::The growing recognition and occurrence of traumatic exposure in the general population has given increased salience to the need to understand the concept of resilience. More than just the "flip side" of a risk factor, the notion of resilience encompasses psychological and biological characteristics, intrinsic to an in...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.20175
更新日期:2007-01-01 00:00:00