Validity of a simpler definition of major depressive disorder.

abstract：:Serotonergic (5-hydroxytryptamine; 5-HT) mechanisms have been implicated in a number of physiological and pathophysiological processes including mood, anxiety, and cognitive functioning. Among the many 5-HT receptor subtypes, the 5-HT2A receptors (5-HT2A-R) seem to be of particular importance in mediating these effect...

journal_title：Depression and anxiety

authors： Cohen H

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Vilazodone, a selective serotonin reuptake inhibitor and 5-HT1A receptor partial agonist, is approved for treating major depressive disorder in adults. This study (NCT01629966 ClinicalTrials.gov) evaluated the efficacy and safety of vilazodone in adults with generalized anxiety disorder (GAD). METHODS:A mul...

journal_title：Depression and anxiety

authors： Gommoll C,Durgam S,Mathews M,Forero G,Nunez R,Tang X,Thase ME

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Recent research suggests that posttraumatic stress disorder (PTSD) is associated with altered amygdala and hippocampal resting-state functional connectivity (rsFC). However, less research has examined whether Prolonged Exposure (PE), a first line exposure-based treatment for PTSD, has the potential to alter ...

journal_title：Depression and anxiety

authors： Zhu X,Suarez-Jimenez B,Lazarov A,Helpman L,Papini S,Lowell A,Durosky A,Lindquist MA,Markowitz JC,Schneier F,Wager TD,Neria Y

更新日期：2018-10-01 00:00:00

abstract：:Reports on the severity and reversibility of cognitive disturbances in major depression in the literature diverge due to methodological biases. The present study, using a precise methodology, examined attention and executive functions in 20 relatively young, depressed patients presenting a first or second episode of u...

journal_title：Depression and anxiety

authors： Constant EL,Adam S,Gillain B,Seron X,Bruyer R,Seghers A

更新日期：2005-01-01 00:00:00

abstract：:A key component of how depression may impact personality pathology involves an understanding of how cognition and dysfunctional attitudes may change as a result of experiencing a depressive state, and how these changes may affect reporting of personality disorder symptoms. This study examines whether dysfunctional att...

journal_title：Depression and anxiety

authors： Farabaugh A,Mischoulon D,Schwartz F,Pender M,Fava M,Alpert J

更新日期：2007-01-01 00:00:00

abstract：:Pediatric psychopharmacology is hindered by the relative lack of controlled, empirical clinical trials [Shatzberg and Nemeroff, 1998: Washington, D.C.: The American Psychiatric Press, Inc. p 301-306]. Psychiatric disorders in children and adolescents carry considerable morbidity, impede development, and carry a signif...

journal_title：Depression and anxiety

authors： Weller EB,Weller RA,Davis GP

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Maintenance of gains with cognitive-behavioral treatment for trichotillomania (TTM) has historically been problematic. METHODS:We conducted follow-up assessments 3 and 6 months after completion of a 3-month maintenance phase on 10 individuals with DSM-IV-TR TTM who participated in an open trial of a dialect...

journal_title：Depression and anxiety

authors： Keuthen NJ,Rothbaum BO,Falkenstein MJ,Meunier S,Timpano KR,Jenike MA,Welch SS

更新日期：2011-04-01 00:00:00

abstract：:This study sought to describe clinical and demographic characteristics differentiating patients with DSM-III-R simple phobias comorbid with one or more of five DSM-III-R index anxiety disorders as compared with those with the index diagnoses alone. From 711 subjects participating in a multicenter, longitudinal, natura...

journal_title：Depression and anxiety

authors： Goisman RM,Allsworth J,Rogers MP,Warshaw MG,Goldenberg I,Vasile RG,Rodriguez-Villa F,Mallya G,Keller MB

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The clinical presentation of panic disorder (PD) is known to be highly heterogeneous, complicating research on its etiology, neurobiological pathways, and treatment. None of the attempts to identify PD subtypes have been independently reproduced, rendering the current literature inconclusive. METHODS:Using ...

journal_title：Depression and anxiety

authors： Pattyn T,Van Den Eede F,Lamers F,Veltman D,Sabbe BG,Penninx BW

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Chronotype is an individual's preferred timing of sleep and activity, and is often referred to as a later chronotype (or evening-type) or an earlier chronotype (or morning-type). Having an evening chronotype is associated with more severe depressive and anxiety symptoms. Based on these findings it is has bee...

journal_title：Depression and anxiety

authors： Druiven SJM,Hovenkamp-Hermelink JHM,Knapen SE,Kamphuis J,Haarman BCM,Penninx BWJH,Antypa N,Meesters Y,Schoevers RA,Riese H

更新日期：2020-05-01 00:00:00

abstract：:Paruresis is characterized by the fear of not being able to urinate in public bathrooms and has been classified by some to be a sub-type of social anxiety disorder (social phobia). Despite the existence of a consumer advocacy organization, the "Intentional Paruresis Association (www.paruresis.org)," there is sparse li...

journal_title：Depression and anxiety

authors： Vythilingum B,Stein DJ,Soifer S

更新日期：2002-01-01 00:00:00

abstract：:Experimental evidence suggests that panic disorder is characterized by abnormalities in the balance system function and that these abnormalities might be related to the severity of agoraphobic avoidance. Since the balance system can be modulated by the serotonergic system, we investigated the effect of a 6-week treatm...

journal_title：Depression and anxiety

authors： Perna G,Alpini D,Caldirola D,Raponi G,Cesarani A,Bellodi L

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Anxiety symptoms are common in adolescence and are often considered developmentally benign. Yet for some, anxiety presents with serious comorbid nonanxiety psychopathology. Early identification of such "malignant" anxiety presentations is a major challenge. We aimed to characterize anxiety symptoms suggestiv...

journal_title：Depression and anxiety

authors： Barzilay R,White LK,Moore TM,Calkins ME,Taylor JH,Patrick A,Huque ZM,Young JF,Ruparel K,Pine DS,Gur RC,Gur RE

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The Generalized Anxiety Disorder Severity Scale (GADSS) is an interview rating scale designed specifically for assessing symptom severity of generalized anxiety disorder (GAD), which has demonstrated positive psychometric data in a sample of adult primary care patients with GAD and panic disorder. However, t...

journal_title：Depression and anxiety

authors： Weiss BJ,Calleo J,Rhoades HM,Novy DM,Kunik ME,Lenze EJ,Stanley MA

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:A history of past major depressive episodes (MDEs) is known to be a risk factor for future MDEs. Additional information about the relationship between past and future episodes would be useful in clinical practice, it is therefore important to fully understand the epidemiology of major depression. We asked wh...

journal_title：Depression and anxiety

authors： Bulloch A,Williams J,Lavorato D,Patten S

更新日期：2014-01-01 00:00:00

abstract：:The current study describes the validation of a new cognitive assessment measure for social phobia, entitled the Appraisal of Social Concerns (ASC). Item content is relevant to a range of social situations. The ASC can be used to tailor interventions to patients' idiosyncratic concerns. Data are presented from both cl...

journal_title：Depression and anxiety

authors： Telch MJ,Lucas RA,Smits JA,Powers MB,Heimberg R,Hart T

更新日期：2004-01-01 00:00:00

abstract：:Pramipexole, a dopamine D2 receptor agonist, was tested in 174 patients with major depression, with or without melancholia and without psychotic features. Three daily dose levels (0.375 mg, 1.0 mg, and 5.0 mg) were compared to fluoxetine (Prozac) at 20 mg and placebo in a randomized, double-blind, parallel-group study...

journal_title：Depression and anxiety

authors： Corrigan MH,Denahan AQ,Wright CE,Ragual RJ,Evans DL

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Although several studies have documented a higher prevalence of psychiatric disorders in children of depressed than nondepressed parents, previous research was conducted in predominantly White, middle, or upper-middle class populations. Only limited information is available on psychiatric disorders and psych...

journal_title：Depression and anxiety

authors： Feder A,Alonso A,Tang M,Liriano W,Warner V,Pilowsky D,Barranco E,Wang Y,Verdeli H,Wickramaratne P,Weissman MM

更新日期：2009-01-01 00:00:00

abstract：:We report the case of adolescent male with obsessive-compulsive disorder (OCD) who had an incomplete response to combined cognitive-behavioral therapy (CBT) and sertraline before successful augmentation of CBT with aripiprazole. Standardized assessments indicated significant reductions in OCD symptomatology associated...

journal_title：Depression and anxiety

authors： Storch EA,Lehmkuhl H,Geffken GR,Touchton A,Murphy TK

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Recent evidence shows that screen time may be an important risk factor for mental health. The aim of this study was to examine the association of computer/mobile devices (CMD) use and TV watching separately with depressive symptoms in a large representative sample of Chinese adults. METHODS:A sample of 18,9...

journal_title：Depression and anxiety

authors： Yu B,Gu Y,Bao X,Meng G,Wu H,Zhang Q,Liu L,Sun S,Wang X,Zhou M,Jia Q,Song K,Niu K

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Panic disorder (PD) is highly comorbid with major depressive disorder (MDD) with potential impact on patient-reported outcomes of quality of life (QOL), functioning, and depressive symptom severity. METHODS:Using data from the sequenced treatment alternatives to relieve depression (STAR*D) trial, we compare...

journal_title：Depression and anxiety

authors： IsHak WW,Mirocha J,Christensen S,Wu F,Kwock R,Behjat J,Pi S,Akopyan A,Peselow ED,Cohen RM,Elashoff D

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Acute stress disorder (ASD) predicts the development of posttraumatic stress disorder (PTSD), which in some sufferers can persist for years and lead to significant disability. We carried out a review of randomized controlled trials to give an update on which psychological treatments are empirically supported...

journal_title：Depression and anxiety

authors： Ponniah K,Hollon SD

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Accumulating evidence suggests that posttraumatic stress disorder (PTSD) is associated with disrupted default mode network (DMN) connectivity, but findings across studies have not been uniform. Individual differences in relevant genes may account for some of the reported variability in the relationship betwe...

journal_title：Depression and anxiety

authors： Miller DR,Logue MW,Wolf EJ,Maniates H,Robinson ME,Hayes JP,Stone A,Schichman S,McGlinchey RE,Milberg WP,Miller MW

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Adolescent depression may increase risk for poor mental health outcomes in adulthood. The objective of this study was to systematically review the literature on the association between adolescent depression and adult anxiety and depressive disorders as well as suicidality. METHODS:EMBASE, MEDLINE, and PSYCi...

journal_title：Depression and anxiety

authors： Johnson D,Dupuis G,Piche J,Clayborne Z,Colman I

更新日期：2018-08-01 00:00:00

abstract：:Anxiety disorders are among the most common psychiatric disorders, affecting one in four individuals over a lifetime. Although our understanding of the etiology of these disorders is incomplete, familial and genetic factors are established risk factors. However, identifying the specific casual genes has been difficult...

journal_title：Depression and anxiety

authors： Smoller JW,Block SR,Young MM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:There has been little research on the generalizability of clinical trials for generalized anxiety disorder (GAD). The present study examines the generalizability of pharmacological and psychotherapy clinical trials' results of individuals with DSM-IV GAD to a large community sample. METHODS:Data were drawn ...

journal_title：Depression and anxiety

authors： Hoertel N,Le Strat Y,Blanco C,Lavaud P,Dubertret C

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Many individuals with obsessive-compulsive disorder (OCD) do not receive professional treatment due to various idiosyncratic barriers. Internet-based cognitive-behavioral therapy (iCBT) is increasingly used to narrow treatment gaps, but the efficacy of such interventions without guidance of therapists has no...

journal_title：Depression and anxiety

authors： Schröder J,Werkle N,Cludius B,Jelinek L,Moritz S,Westermann S

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Previous work on gene-environment (GxE) interplay concerning anxiety has focused on the interaction of 5-HTTLPR with childhood adversities or traumatic events whereas the impact of recent stressors is understudied, as is the integration of resilience. The current study aimed to investigate the interactive ef...

journal_title：Depression and anxiety

authors： Ollmann TM,Voss C,Venz J,Seidl E,Hoyer J,Kische H,Pieper L,Schiele MA,Domschke K,Beesdo-Baum K

更新日期：2020-10-14 00:00:00

abstract：BACKGROUND:Processes of phasic fear responses to threatening stimuli are thought to be distinct from sustained, anticipatory anxiety toward an unpredicted, potential threat. There is evidence for dissociable neural correlates of phasic fear and sustained anxiety. Whereas increased amygdala activity has been associated ...

journal_title：Depression and anxiety

authors： Münsterkötter AL,Notzon S,Redlich R,Grotegerd D,Dohm K,Arolt V,Kugel H,Zwanzger P,Dannlowski U

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Brain structures underlying posttraumatic stress disorder (PTSD) have been a focus of imaging studies, but associations between treatment outcome and alterations in brain structures remain largely unexamined. We longitudinally examined the relation of structural changes in the rostral anterior cingulate cort...

journal_title：Depression and anxiety

authors： Helpman L,Papini S,Chhetry BT,Shvil E,Rubin M,Sullivan GM,Markowitz JC,Mann JJ,Neria Y

更新日期：2016-05-01 00:00:00