Abstract:
:Pediatric psychopharmacology is hindered by the relative lack of controlled, empirical clinical trials [Shatzberg and Nemeroff, 1998: Washington, D.C.: The American Psychiatric Press, Inc. p 301-306]. Psychiatric disorders in children and adolescents carry considerable morbidity, impede development, and carry a significant mortality by suicide. Therefore, there is a need for studies of antidepressants and other psychotropics in children and adolescents. This article reviews the preliminary evidence that venlafaxine (Effexor), a novel antidepressant, may be useful in children and adolescents with a variety of psychiatric disorders.
journal_name
Depress Anxietyjournal_title
Depression and anxietyauthors
Weller EB,Weller RA,Davis GPdoi
10.1002/1520-6394(2000)12:1+<85::AID-DA12>3.0.CO;2subject
Has Abstractpub_date
2000-01-01 00:00:00pages
85-9eissn
1091-4269issn
1520-6394journal_volume
12 Suppl 1pub_type
杂志文章,评审abstract:BACKGROUND:Internet-delivered cognitive behavioral therapy (iCBT) is a relatively novel treatment method that may improve the accessibility of mental health care for individuals with posttraumatic stress disorder (PTSD). The aim of this meta-analysis was to evaluate the effectiveness of iCBT compared to inactive (waitl...
journal_title:Depression and anxiety
pub_type: 杂志文章,meta分析,评审
doi:10.1002/da.22533
更新日期:2016-09-01 00:00:00
abstract::Internet-delivered cognitive behavioral therapy (iCBT) was developed to overcome some of the barriers in accessing best practice face-to-face CBT. iCBT affords many benefits, such as high fidelity, greater accessibility, convenience, and reduced cost to patients and health-care systems. Recent meta-analyses of iCBT fo...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22302
更新日期:2014-11-01 00:00:00
abstract:BACKGROUND:Fear overgeneralization is a central feature of anxiety disorders and can lead to excessive avoidance. As perceptual discrimination is a key component of fear overgeneralization, a perceptual discrimination training task was created aimed at improving perceptual discrimination and reducing fear overgeneraliz...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.22930
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVE:To determine the factors, which are associated with suicidal ideation and ideas of self-harm in patients with congestive heart failure (CHF). METHODS:We examined 294 patients with documented CHF, New York Heart Association (NYHA) functional class II-IV, in a cross sectional study at three cardiac outpatient ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20587
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Neural activity is increasingly used in addition to behavioral measures to study anxiety and attentional biases toward threatening stimuli. Event-related potentials (ERPs) might be particularly useful because of their excellent temporal resolution. In particular, the late positive potential (LPP) reflects in...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20679
更新日期:2010-03-01 00:00:00
abstract::Sensitization of stress-responsive neurobiological systems as a possible consequence of early adverse experience has been implicated in the pathophysiology of mood and anxiety disorders. In addition to early adversities, adulthood stressors are also known to precipitate the manifestation of these disorders. The presen...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.10015
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:We used a dot-probe paradigm to examine attention bias toward threat (i.e., angry) and happy face stimuli in severe mood dysregulation (SMD) versus healthy comparison (HC) youth. The tendency to allocate attention to threat is well established in anxiety and other disorders of negative affect. SMD is charact...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22145
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Reducing access to lethal means (especially firearms) might prevent suicide, but counseling of at-risk individuals about this strategy may not be routine. Among emergency department (ED) patients with suicidal ideation or attempts (SI/SA), we sought to describe home firearm access and examine ED provider ass...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22486
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:To elucidate mechanisms related to remission in winter seasonal affective disorder (SAD), we explored the course of individual depressive symptom offset across two distinct treatment modalities that show comparable outcomes at treatment endpoint: cognitive-behavioral therapy for SAD (CBT-SAD) and light thera...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.22739
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Controversy surrounds the question of whether agoraphobia (AG) exists as an independent diagnostic entity apart from panic. In favor of this position, AG without panic disorder (PD) in parents was found being unrelated to offsprings' risk for AG or PD, albeit it may enhance the familial transmission of PD (N...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.21975
更新日期:2012-11-01 00:00:00
abstract::Since the introduction of the concept of social anxiety (or phobia) to the American nosological system in DSM-III (1980), it has become increasingly apparent that the condition is also prevalent in other cultures. In Japan, for example, the condition, called taijinkyofusho (usually abbreviated as TKS in English), is w...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/(sici)1520-6394(1997)5:3<115::aid-da1>3.0.
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Childhood maltreatment has been associated with symptom severity, reduced quality of life, and impaired functioning in adults with social anxiety disorder (SAD). No study has investigated how childhood maltreatment impacts pharmacotherapy outcomes in this population, despite evidence for such a link in depre...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20909
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Actigraphy may provide a more valid assessment of sleep, circadian rhythm (CR), and physical activity (PA) than self-reported questionnaires, but has not been used widely to study the association with depression/anxiety and their clinical characteristics. METHODS:Fourteen-day actigraphy data of 359 particip...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22949
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Although losses are important consequences of disasters, few epidemiological studies of disasters have assessed complicated grief (CG) and none assessed CG associated with losses other than death of loved one. METHODS:Data come from the baseline survey of the Hurricane Katrina Community Advisory Group, a re...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20865
更新日期:2011-08-01 00:00:00
abstract::This study explores the psychometric properties of the Portuguese version of Corah's Dental Anxiety Scale (DAS), an instrument designed to assess the manifestations of dental anxiety. The DAS has been translated into several languages, but no adaptation and reliability analysis of the Portuguese version of the scale h...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20258
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:Comparing the overall and differential effects of psychodynamic psychotherapy (PDT) versus cognitive behavior therapy (CBT) for social anxiety disorder (SAD). DESIGN:Patients with a primary SAD (N = 47) were randomly assigned to PDT (N = 22) or CBT (N = 27). Both PDT and CBT consisted of up to 36 sessions (...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.22246
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND/OBJECTIVE:The role of the neuropeptide oxytocin (OT) in Borderline Personality Disorder (BPD) is poorly understood. It is particularly unknown how early experiences with caregivers moderate the action of OT in BPD. Here, we examined the association of plasma OT levels in BPD patients with the experience of c...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22683
更新日期:2018-01-01 00:00:00
abstract::This study used an open clinical trial to test a cognitive-behavioral treatment for public-speaking anxiety that utilized virtual reality as a tool for exposure therapy. Treatment was completed by participants (n = 10) meeting the Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV criteria for social phobi...
journal_title:Depression and anxiety
pub_type: 临床试验,杂志文章
doi:10.1002/da.20090
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Previous work has shown that inhibition of fear is impaired in posttraumatic stress disorder (PTSD) resulting from both civilian and combat trauma. The purpose of the present study was to investigate the inhibition of learned fear in traumatized individuals diagnosed with either acute stress disorder (ASD) o...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.21991
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Depression outcomes in research and clinical practice are commonly defined by the concepts of remission, recovery, relapse, and recurrence. Despite their widespread use, there has been little empirical examination of these concepts. Therefore, we investigated profiles of individual symptoms during each of th...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.21960
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:To examine the potential mediating role of parenting behaviors in the longitudinal, bidirectional relationships between maternal depression and child internalizing symptoms (i.e. depression and anxiety). METHODS:We analyzed data from 4,581 mother-child dyads from the Fragile Families and Child Wellbeing Stu...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22688
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Anxiety symptoms are common in adolescence and are often considered developmentally benign. Yet for some, anxiety presents with serious comorbid nonanxiety psychopathology. Early identification of such "malignant" anxiety presentations is a major challenge. We aimed to characterize anxiety symptoms suggestiv...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.23060
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Although diagnostically dissociable, anxiety is strongly co-morbid with depression. To examine further the clinical symptoms of anxiety in major depressive disorder (MDD), a non-parametric item response analysis on "blinded" data from four pharmaceutical company clinical trials was performed on the Hamilton ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20435
更新日期:2008-01-01 00:00:00
abstract::Reports on the severity and reversibility of cognitive disturbances in major depression in the literature diverge due to methodological biases. The present study, using a precise methodology, examined attention and executive functions in 20 relatively young, depressed patients presenting a first or second episode of u...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20060
更新日期:2005-01-01 00:00:00
abstract::Although the use of telemedicine in psychiatry has a long history in providing clinical care to patients, its use in clinical trials research has not yet been commonly employed. Telemedicine allows for the remote assessment of study patients, which could be done by a centralized, highly calibrated, and impartial cohor...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20392
更新日期:2008-01-01 00:00:00
abstract::This study assessed striatal dopamine 1 (D1) receptor binding in patients with major depressive disorder and anger attacks (MDD+A) and healthy volunteers. We used positron emission tomography with [(11)C]SCH 23,390 to compare 10 patients with MDD+A to 10 healthy volunteers. [(11)C]SCH 23,390 binding in bilateral stria...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20168
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:The link between systemic inflammation and depression has been deeply investigated, but relatively few studies explored symptom-specific associations, mostly focusing on common inflammatory biomarkers like C-reactive protein (CRP) levels. METHODS:We investigated associations of low-grade inflammation with d...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.23070
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Social anxiety disorder (SAD) is an incapacitating disorder running in families. Previous work associated social fearfulness with a failure to habituate, but the habituation response to neutral faces has, as of yet, not been investigated in patients with SAD and their family members concurrently. Here, we ex...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22962
更新日期:2019-12-01 00:00:00
abstract::Depressed patients who rapidly metabolize antidepressants may be common, and may not respond to even high doses of antidepressants if subtherapeutic plasma levels are produced. Rapid metabolizers (RMs) are identifiable if patients are on tricyclic antidepressants (TCAs), and TCA plasma levels (commonly available) are ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/(SICI)1520-6394(1996)4:6<320::AID-DA8>3.0.
更新日期:1996-01-01 00:00:00
abstract::The selective serotonin reuptake inhibitors (SSRIs) are recognized as effective as and better tolerated than older antidepressant therapies and have become the drugs of choice in the treatment of mild to moderate depression. However, there is a clinical impression that the SSRIs are less effective than older therapies...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1520-6394(1996)4:4<182::AID-DA4>3.0.
更新日期:1996-01-01 00:00:00