Getting straight about grief.

abstract：:Increasing attention has been paid to the role of inflammation in a host of illnesses including neuropsychiatric disorders such as depression and anxiety. Activation of the inflammatory response leads to release of inflammatory cytokines and mobilization of immune cells both of which have been shown to access the brai...

journal_title：Depression and anxiety

authors： Miller AH,Haroon E,Raison CL,Felger JC

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Posttraumatic stress disorder (PTSD) is associated with significant health risk, illness, and functional impairment, e.g., Green and Kimerling [2004: Physical Health Consequences of Exposure to Extreme Stress. Washington, DC: American Psychological Association] Kimerling et al. [2000: Trauma and Health: J Tr...

journal_title：Depression and anxiety

authors： Rauch SA,Grunfeld TE,Yadin E,Cahill SP,Hembree E,Foa EB

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Hypothalamic-pituitary-adrenal (HPA) axis functioning has been implicated in the development of stress-related psychiatric diagnoses and response to adverse life experiences. This study aimed to investigate the association between genetic and epigenetics in HPA axis and response to cognitive behavior therapy...

journal_title：Depression and anxiety

authors： Roberts S,Keers R,Lester KJ,Coleman JR,Breen G,Arendt K,Blatter-Meunier J,Cooper P,Creswell C,Fjermestad K,Havik OE,Herren C,Hogendoorn SM,Hudson JL,Krause K,Lyneham HJ,Morris T,Nauta M,Rapee RM,Rey Y,Schneider S

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Treatment utilization/costs and work performance for persons with major depressive disorder (MDD) by severity of illness is not well documented. METHODS:Using National Comorbidity Survey-Replication (2001-2002) data, US workforce respondents (n=4,465) were classified by clinical severity (not clinically dep...

journal_title：Depression and anxiety

authors： Birnbaum HG,Kessler RC,Kelley D,Ben-Hamadi R,Joish VN,Greenberg PE

更新日期：2010-01-01 00:00:00

abstract：:In this analysis we examined studies of tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) to compare efficacy and drop-out rates. Frequency of reported side effects was also studied. Using Medline, we located 36 clinical trials of TCAs and SSRIs in a double-blind comparison. We perfo...

journal_title：Depression and anxiety

authors： Steffens DC,Krishnan KR,Helms MJ

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:This study examined the feasibility and preliminary effectiveness of d-cycloserine (DCS)-augmented cognitive behavioral therapy (CBT) for children and adolescents with difficult-to-treat Obsessive Compulsive Disorder, in a double-blind randomized controlled pilot trial (RCT). METHODS:Seventeen children and ...

journal_title：Depression and anxiety

authors： Farrell LJ,Waters AM,Boschen MJ,Hattingh L,McConnell H,Milliner EL,Collings N,Zimmer-Gembeck M,Shelton D,Ollendick TH,Testa C,Storch EA

更新日期：2013-08-01 00:00:00

abstract：:The current study describes the validation of a new cognitive assessment measure for social phobia, entitled the Appraisal of Social Concerns (ASC). Item content is relevant to a range of social situations. The ASC can be used to tailor interventions to patients' idiosyncratic concerns. Data are presented from both cl...

journal_title：Depression and anxiety

authors： Telch MJ,Lucas RA,Smits JA,Powers MB,Heimberg R,Hart T

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:In this study, we examined executive control of attention in individuals with contamination-related obsessive-compulsive (OC) symptoms using a modified version of the Eriksen flanker task. The task indexes one's ability to resolve attentional conflict between different responses and to ignore task distracter...

journal_title：Depression and anxiety

authors： Najmi S,Hindash AC,Amir N

更新日期：2010-09-01 00:00:00

abstract：:Functional impairment might amplify suicide risk in later life. A positive view of the future may reduce this risk. We tested the hypothesis that hopelessness and positive future orientation moderate the association between functional status and suicide ideation in a sample of 136 patients, 55 years of age or older, i...

journal_title：Depression and anxiety

authors： Hirsch JK,Duberstein PR,Conner KR,Heisel MJ,Beckman A,Franus N,Conwell Y

更新日期：2007-01-01 00:00:00

abstract：:This study seeks to determine how panic disorder patients with anxiety and depression comorbidity differ from panic disorder patients without comorbidity at the time of presentation for treatment. One-hundred seventy-one panic disorder patients presenting for their initial assessment and treatment at the Payne Whitney...

journal_title：Depression and anxiety

authors： Apfeldorf WJ,Spielman LA,Cloitre M,Heckelman L,Shear MK

更新日期：2000-01-01 00:00:00

abstract：:Sensitization of stress-responsive neurobiological systems as a possible consequence of early adverse experience has been implicated in the pathophysiology of mood and anxiety disorders. In addition to early adversities, adulthood stressors are also known to precipitate the manifestation of these disorders. The presen...

journal_title：Depression and anxiety

authors： Heim C,Newport DJ,Wagner D,Wilcox MM,Miller AH,Nemeroff CB

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Previous work on gene-environment (GxE) interplay concerning anxiety has focused on the interaction of 5-HTTLPR with childhood adversities or traumatic events whereas the impact of recent stressors is understudied, as is the integration of resilience. The current study aimed to investigate the interactive ef...

journal_title：Depression and anxiety

authors： Ollmann TM,Voss C,Venz J,Seidl E,Hoyer J,Kische H,Pieper L,Schiele MA,Domschke K,Beesdo-Baum K

更新日期：2020-10-14 00:00:00

abstract：OBJECTIVE:The impact of childhood adversity persists across the life course. This study aimed to investigate the associations of childhood adversity with the course, suicidality, and treatment outcomes of depressive disorders. METHOD:A total of 919 people with depressive disorders were recruited. Childhood adversities...

journal_title：Depression and anxiety

authors： Kim SW,Kang HJ,Kim SY,Kim JM,Yoon JS,Jung SW,Lee MS,Yim HW,Jun TY

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:A significant proportion of soldiers return from deployment with symptoms of fatigue, sleep difficulties, and posttraumatic complaints. Disrupted sleep has been proposed as a contributing factor for the development of posttraumatic stress disorder (PTSD). This study investigates the impact of impaired sleep ...

journal_title：Depression and anxiety

authors： van Liempt S,van Zuiden M,Westenberg H,Super A,Vermetten E

更新日期：2013-05-01 00:00:00

abstract：:Little is known about the beliefs of patients suffering from major depression as to the causes of their illness and effective treatments. This study introduces a new instrument for capturing these beliefs, the Explanatory Model for Depression (EMD) Questionnaire, and explores the beliefs of patients participating in a...

journal_title：Depression and anxiety

authors： Bann CM,Parker CB,Bradwejn J,Davidson JR,Vitiello B,Gadde KM

更新日期：2004-01-01 00:00:00

abstract：:Effective treatment of severe or chronic unipolar depression requires the combination of pharmacological and psychotherapeutic interventions, and demands a theoretical paradigm integrating biological and psychosocial aspects of depression. Supported by recent research, we propose in our article a biopsychosocial diath...

journal_title：Depression and anxiety

authors： Schotte CK,Van Den Bossche B,De Doncker D,Claes S,Cosyns P

更新日期：2006-01-01 00:00:00

abstract：:Age at onset is an important dimension in the classification of mood disorders. Recent findings on early-onset (EO) versus late-onset (LO) unipolar chronic depressions support this subtyping. The aim of the present study was to determine clinical differences between EO and LO bipolar II chronic depression and to suppo...

journal_title：Depression and anxiety

authors： Benazzi F

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Depression is a highly prevalent disease with a high morbidity and mortality risk. Its pathophysiology is not entirely clear. However, type 2 diabetes is an important risk factor for depression. One mechanism that may explain this association may include the formation of advanced glycation end products (AGEs...

journal_title：Depression and anxiety

authors： van Dooren FE,Pouwer F,Schalkwijk CG,Sep SJ,Stehouwer CD,Henry RM,Dagnelie PC,Schaper NC,van der Kallen CJ,Koster A,Denollet J,Verhey FR,Schram MT

更新日期：2017-01-01 00:00:00

abstract：:This study sought to describe clinical and demographic characteristics differentiating patients with DSM-III-R simple phobias comorbid with one or more of five DSM-III-R index anxiety disorders as compared with those with the index diagnoses alone. From 711 subjects participating in a multicenter, longitudinal, natura...

journal_title：Depression and anxiety

authors： Goisman RM,Allsworth J,Rogers MP,Warshaw MG,Goldenberg I,Vasile RG,Rodriguez-Villa F,Mallya G,Keller MB

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:There is ample evidence of the efficacy of cognitive-behavioral therapy (CBT) for depression in adolescents, including Puerto Rican adolescents. However, there is still a high percentage of adolescents who do not respond to a standard "dose" of 12 sessions of CBT. This clinical case study explores the charac...

journal_title：Depression and anxiety

authors： Jiménez Chafey MI,Bernal G,Rosselló J

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The impact of the May 2008 Wenchuan earthquake, measuring a massive 8.0 on the surface wave magnitude scale, on public health in China has been significant and multifaceted. In light of extant data on prevalence and risk factors for posttraumatic stress disorder (PTSD) after other natural diasters, we collec...

journal_title：Depression and anxiety

authors： Kun P,Han S,Chen X,Yao L

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Controversy surrounds the question of whether agoraphobia (AG) exists as an independent diagnostic entity apart from panic. In favor of this position, AG without panic disorder (PD) in parents was found being unrelated to offsprings' risk for AG or PD, albeit it may enhance the familial transmission of PD (N...

journal_title：Depression and anxiety

authors： Knappe S,Beesdo-Baum K,Nocon A,Wittchen HU

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Metacognitive therapy (MCT) is a relatively new approach to treating mental disorders. The aim of the current meta-analysis was to examine the efficacy of MCT in patients with mental disorders. METHOD:A comprehensive literature search revealed 16 published as well as unpublished studies on the efficacy of M...

journal_title：Depression and anxiety

authors： Normann N,van Emmerik AA,Morina N

更新日期：2014-05-01 00:00:00

abstract：:The diagnosis of anxiety disorders and major depression can be reliably made based on signs and symptoms. However there are significant limitations to the current system of classification including overlapping criteria, high comorbidity, and the issue of subthreshold syndromes. The literature on treatment response doc...

journal_title：Depression and anxiety

authors： Ninan PT,Berger J

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Vilazodone, a selective serotonin reuptake inhibitor and 5-HT1A receptor partial agonist, is approved for treating major depressive disorder in adults. This study (NCT01629966 ClinicalTrials.gov) evaluated the efficacy and safety of vilazodone in adults with generalized anxiety disorder (GAD). METHODS:A mul...

journal_title：Depression and anxiety

authors： Gommoll C,Durgam S,Mathews M,Forero G,Nunez R,Tang X,Thase ME

更新日期：2015-06-01 00:00:00

abstract：:There are well-established sex differences in the prevalence of certain mental disorders. Work in animal models has provided us with an emerging understanding of the role that epigenetic factors play in establishing sex differences in the brain during development. Similarly, work in animal models, and a more limited b...

journal_title：Depression and anxiety

authors： Uddin M,Sipahi L,Li J,Koenen KC

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Understanding cognitive and biological mechanisms of PTSD treatment can help refine treatments and increase rates of response. METHODS:Thirty-six veterans with PTSD were randomly assigned to receive Prolonged exposure therapy (PE) or Present-Centered therapy (PCT). We examined symptoms, trauma-related cogni...

journal_title：Depression and anxiety

authors： Rauch SA,King AP,Abelson J,Tuerk PW,Smith E,Rothbaum BO,Clifton E,Defever A,Liberzon I

更新日期：2015-03-01 00:00:00

abstract：:There is abundant evidence for abnormalities of the norepinephrine (NE) and serotonin (5HT) neurotransmitter systems in depression and anxiety disorders. The majority of evidence supports underactivation of serotonergic function and complex dysregulation of noradrenergic function, most consistent with overactivation o...

journal_title：Depression and anxiety

authors： Ressler KJ,Nemeroff CB

更新日期：2000-01-01 00:00:00

abstract：:This paper discusses the role of psychosocial intervention in the treatment of suicidal youth, summarizes the existing relevant literature, describes model programs for treating suicidal youth, and discusses efficacy-to-effectiveness issues in working with this population. ...

journal_title：Depression and anxiety

authors： Fristad MA,Shaver AE

更新日期：2001-01-01 00:00:00

abstract：:The American Psychiatric Association and the World Health Organization have begun to revise their classifications of mental disorders. Four issues related to these revisions are discussed in this study: the structure of the classifications, the relationship between categories and dimensions, the sensitivity of categor...

journal_title：Depression and anxiety

authors： Andrews G,Anderson TM,Slade T,Sunderland M

更新日期：2008-01-01 00:00:00