Difficult-to-treat pediatric obsessive-compulsive disorder: feasibility and preliminary results of a randomized pilot trial of D-cycloserine-augmented behavior therapy.

abstract：BACKGROUND:Psychiatrists frequently struggle with how to sequence treatment for depressed adolescents who do not respond to an adequate trial of a selective serotonin reuptake inhibitor (SSRI). This study leveraged recent statistical and computational advances to create Bayesian hierarchal models (BHMs) of response in ...

journal_title：Depression and anxiety

authors： Suresh V,Mills JA,Croarkin PE,Strawn JR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Comorbid psychiatric disorders, cardiovascular disease, chronic hypertension, diabetes, and musculoskeletal disorders are highly prevalent in depression. However, the extent to which these conditions affect the recurrence of depression-related work disability is unknown. The specific aims of the study were t...

journal_title：Depression and anxiety

authors： Ervasti J,Vahtera J,Pentti J,Oksanen T,Ahola K,Kivekäs T,Kivimäki M,Virtanen M

更新日期：2014-09-01 00:00:00

abstract：:Research on the effects of childhood trauma has been limited by the lack of a comprehensive, reliable, and valid instrument that assesses the occurrence of early traumatic experiences. This paper presents the development and preliminary psychometric properties of an instrument, the Early Trauma Inventory (ETI), for th...

journal_title：Depression and anxiety

authors： Bremner JD,Vermetten E,Mazure CM

更新日期：2000-01-01 00:00:00

abstract：:Age at onset is an important dimension in the classification of mood disorders. Recent findings on early-onset (EO) versus late-onset (LO) unipolar chronic depressions support this subtyping. The aim of the present study was to determine clinical differences between EO and LO bipolar II chronic depression and to suppo...

journal_title：Depression and anxiety

authors： Benazzi F

更新日期：2001-01-01 00:00:00

abstract：:Increasing attention has been paid to the role of inflammation in a host of illnesses including neuropsychiatric disorders such as depression and anxiety. Activation of the inflammatory response leads to release of inflammatory cytokines and mobilization of immune cells both of which have been shown to access the brai...

journal_title：Depression and anxiety

authors： Miller AH,Haroon E,Raison CL,Felger JC

更新日期：2013-04-01 00:00:00

abstract：:This study examined the validity of the Assessment of Depression Inventory (ADI), a 39-item measure of depression with three embedded validity scales, using inpatient participants. The ADI Depression (Dep) and Feigning (Fg) scales were compared to the corresponding scales of a widely used multiscale instrument, the Pe...

journal_title：Depression and anxiety

authors： Mogge NL

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Depression and substance use disorders (SUDs) commonly co-occur, which presents diagnostic challenges in classifying independent major depressive disorder (MDD) versus substance-induced depressive disorder (SIDD). It remains unclear if distinct characteristics and/or patterns in temporal course distinguish M...

journal_title：Depression and anxiety

authors： Magidson JF,Wang S,Lejuez CW,Iza M,Blanco C

更新日期：2013-06-01 00:00:00

abstract：:Previous studies have revealed altered structural development of the frontal lobes and prefrontal cortex (PFC) in children with symptoms of posttraumatic stress disorder (PTSD). This study is the first to provide a detailed structural analysis of the PFC in children with and without PTSD symptoms. We compared gray and...

journal_title：Depression and anxiety

authors： Richert KA,Carrion VG,Karchemskiy A,Reiss AL

更新日期：2006-01-01 00:00:00

abstract：:This study examined sex differences in the use of coping strategies and their relationship to depression and anxiety-related psychopathology. Responses on measures of coping strategies, depression, and anxiety were obtained from a carefully screened nonclinical sample (N = 107). The results demonstrated that women who...

journal_title：Depression and anxiety

authors： Kelly MM,Tyrka AR,Price LH,Carpenter LL

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:Comparing the overall and differential effects of psychodynamic psychotherapy (PDT) versus cognitive behavior therapy (CBT) for social anxiety disorder (SAD). DESIGN:Patients with a primary SAD (N = 47) were randomly assigned to PDT (N = 22) or CBT (N = 27). Both PDT and CBT consisted of up to 36 sessions (...

journal_title：Depression and anxiety

authors： Bögels SM,Wijts P,Oort FJ,Sallaerts SJ

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Treatment utilization/costs and work performance for persons with major depressive disorder (MDD) by severity of illness is not well documented. METHODS:Using National Comorbidity Survey-Replication (2001-2002) data, US workforce respondents (n=4,465) were classified by clinical severity (not clinically dep...

journal_title：Depression and anxiety

authors： Birnbaum HG,Kessler RC,Kelley D,Ben-Hamadi R,Joish VN,Greenberg PE

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Although trauma-focused cognitive behavioral therapy (TF-CBT) is the frontline treatment for posttraumatic stress disorder (PTSD), at least one-third of patients are treatment nonresponders. This study aimed to identify neural markers of treatment response, specifically the prediction of remission of specifi...

journal_title：Depression and anxiety

authors： Bryant RA,Erlinger M,Felmingham K,Malhi GS,O'Donnell ML,Williams LM,Korgaonkar MS

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The impact of the May 2008 Wenchuan earthquake, measuring a massive 8.0 on the surface wave magnitude scale, on public health in China has been significant and multifaceted. In light of extant data on prevalence and risk factors for posttraumatic stress disorder (PTSD) after other natural diasters, we collec...

journal_title：Depression and anxiety

authors： Kun P,Han S,Chen X,Yao L

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Social anxiety disorder (SAD) is an incapacitating disorder running in families. Previous work associated social fearfulness with a failure to habituate, but the habituation response to neutral faces has, as of yet, not been investigated in patients with SAD and their family members concurrently. Here, we ex...

journal_title：Depression and anxiety

authors： Bas-Hoogendam JM,van Steenbergen H,Blackford JU,Tissier RLM,van der Wee NJA,Westenberg PM

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Synchronized transcranial magnetic stimulation (sTMS) is a new modality to reduce symptoms of major depressive disorder (MDD). sTMS uses rotating neodymium magnets to deliver low-field stimulation matched to the individual alpha frequency (IAF). A previous multisite study showed that sTMS significantly reduc...

journal_title：Depression and anxiety

authors： Philip NS,Leuchter AF,Cook IA,Massaro J,Goethe JW,Carpenter LL

更新日期：2019-03-01 00:00:00

abstract：:The objective was to present naturalistic 1-year follow-up information of 96 child and adolescent outpatients with major depressive disorder who had been randomized in an 8-week double-blind, placebo-controlled trial of fluoxetine. Subjects were children and adolescents, ages 8-18 years, who were entered in a randomiz...

journal_title：Depression and anxiety

authors： Emslie GJ,Rush AJ,Weinberg WA,Kowatch RA,Carmody T,Mayes TL

更新日期：1998-01-01 00:00:00

abstract：:Shame has been observed to play an important role in social anxiety in China [Xu, 1982]. Shame and personality factors, such as neuroticism and introversion-extraversion, are also related to social anxiety symptoms in Chinese college students [Li et al., 2003]. The aim of this study was to explore cross-cultural diffe...

journal_title：Depression and anxiety

authors： Zhong J,Wang A,Qian M,Zhang L,Gao J,Yang J,Li B,Chen P

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Exposure therapy, a gold-standard treatment for anxiety disorders, is assumed to work via extinction learning, but this has never been tested. Anxious individuals demonstrate extinction learning deficits, likely related to less ventromedial prefrontal cortex (vmPFC) and more amygdala activation, but the rela...

journal_title：Depression and anxiety

authors： Ball TM,Knapp SE,Paulus MP,Stein MB

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Although losses are important consequences of disasters, few epidemiological studies of disasters have assessed complicated grief (CG) and none assessed CG associated with losses other than death of loved one. METHODS:Data come from the baseline survey of the Hurricane Katrina Community Advisory Group, a re...

journal_title：Depression and anxiety

authors： Shear MK,McLaughlin KA,Ghesquiere A,Gruber MJ,Sampson NA,Kessler RC

更新日期：2011-08-01 00:00:00

abstract：:Disrupted sensory filtering, or problems with suppressing irrelevant environmental sensory stimuli, has been reported in individuals with posttraumatic stress disorder (PTSD). However, the relationship of sensory filtering deficits to specific PTSD symptoms versus an association with general trauma exposure is unclear...

journal_title：Depression and anxiety

authors： Stewart LP,White PM

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Bipolar disorder (BD) is highly familial, but studies have yet to examine preschoolers at risk for BD using standardized, developmentally appropriate clinical assessment tools. We used such methods to test whether preschoolers at familial risk for BD have more observed difficulty modulating emotions and beha...

journal_title：Depression and anxiety

authors： Tseng WL,Guyer AE,Briggs-Gowan MJ,Axelson D,Birmaher B,Egger HL,Helm J,Stowe Z,Towbin KA,Wakschlag LS,Leibenluft E,Brotman MA

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Vilazodone, a selective serotonin reuptake inhibitor and 5-HT1A receptor partial agonist, is approved for treating major depressive disorder in adults. This study (NCT01629966 ClinicalTrials.gov) evaluated the efficacy and safety of vilazodone in adults with generalized anxiety disorder (GAD). METHODS:A mul...

journal_title：Depression and anxiety

authors： Gommoll C,Durgam S,Mathews M,Forero G,Nunez R,Tang X,Thase ME

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:There is evidence that negative affect (NA) and anxiety sensitivity (AS) predict the development of anxiety disorders, particularly panic disorder (PD). The main purpose of this study was to examine whether NA and AS will also predict the clinical course of PD. METHODS:Participants were 136 individuals with...

journal_title：Depression and anxiety

authors： Benítez CI,Shea MT,Raffa S,Rende R,Dyck IR,Ramsawh HJ,Edelen MO,Keller MB

更新日期：2009-01-01 00:00:00

abstract：:Since the introduction of the concept of social anxiety (or phobia) to the American nosological system in DSM-III (1980), it has become increasingly apparent that the condition is also prevalent in other cultures. In Japan, for example, the condition, called taijinkyofusho (usually abbreviated as TKS in English), is w...

journal_title：Depression and anxiety

authors： Chang SC

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:A history of past major depressive episodes (MDEs) is known to be a risk factor for future MDEs. Additional information about the relationship between past and future episodes would be useful in clinical practice, it is therefore important to fully understand the epidemiology of major depression. We asked wh...

journal_title：Depression and anxiety

authors： Bulloch A,Williams J,Lavorato D,Patten S

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Evidence-based treatments for post-traumatic stress disorder (PTSD) have poor uptake and remission rates, suggesting that alternative treatments are needed. Morning bright light may be an effective treatment for PTSD given its established effects on mood and sleep, however, there are no published trials. ME...

journal_title：Depression and anxiety

authors： Zalta AK,Bravo K,Valdespino-Hayden Z,Pollack MH,Burgess HJ

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Although evidence-based psychotherapies (EBPs) for posttraumatic stress disorder (PTSD) were implemented starting in 2005 in the veterans health administration (VHA), the largest national healthcare system in the U.S., the rate of initiation (uptake) and prevalence of these treatments in each calendar year h...

journal_title：Depression and anxiety

authors： Maguen S,Holder N,Madden E,Li Y,Seal KH,Neylan TC,Lujan C,Patterson OV,DuVall SL,Shiner B

更新日期：2020-04-01 00:00:00

abstract：:Progestational hormones may have anxiolytic properties. CCK-4 (cholecystokinin tetrapeptide) can be used pharmacologically to induce panic attacks both in normal controls and patients suffering from panic disorder. In this study we compared the effects of pretreatment with the progestational hormone megestrol and plac...

journal_title：Depression and anxiety

authors： Raedler TJ,Jahn H,Goedeken B,Gescher DM,Kellner M,Wiedemann K

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Although a large body of empirical research has examined negative psychological outcomes in older veterans, relatively little is known about the prevalence and determinants of psychological resilience in this population. METHODS:A nationally representative sample of 2,025 U.S. veterans aged 60 and older (me...

journal_title：Depression and anxiety

authors： Pietrzak RH,Cook JM

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Despite its popularity, little is known about the measurement invariance of the Patient Health Questionnaire-9 (PHQ-9) across U.S. sociodemographic groups. Use of a screener shown not to possess measurement invariance could result in under/over-detection of depression, potentially exacerbating sociodemograph...

journal_title：Depression and anxiety

authors： Patel JS,Oh Y,Rand KL,Wu W,Cyders MA,Kroenke K,Stewart JC

更新日期：2019-09-01 00:00:00