Abstract:
:Age at onset is an important dimension in the classification of mood disorders. Recent findings on early-onset (EO) versus late-onset (LO) unipolar chronic depressions support this subtyping. The aim of the present study was to determine clinical differences between EO and LO bipolar II chronic depression and to support this subtyping also in bipolar II. Eighty-seven consecutive bipolar II chronic depression outpatients were interviewed with the Structured Clinical Interview for DSM-IV, the Montgomery Asberg Depression Rating Scale, and the Global Assessment of Functioning scale. EO cut-offs were 21 and 23 years of age. Variables, studied with linear and logistic regression, were age, gender, age at onset, illness duration, recurrences, atypical, melancholic, and psychotic features, axis I comorbidity, and severity. Lower age at onset was significantly associated with lower age, longer illness duration, less psychosis, less severity, more atypical features, and more axis I comorbidity. Results support the subtyping of bipolar II chronic depression in EO and LO on the basis of different clinical features.
journal_name
Depress Anxietyjournal_title
Depression and anxietyauthors
Benazzi Fdoi
10.1002/1520-6394(2001)13:1<45::aid-da7>3.0.co;2-4subject
Has Abstractpub_date
2001-01-01 00:00:00pages
45-9issue
1eissn
1091-4269issn
1520-6394pii
10.1002/1520-6394(2001)13:1<45::AID-DA7>3.0.CO;2-4journal_volume
13pub_type
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