Psychological distress and comorbid physical conditions: disease or disability?

abstract：BACKGROUND:Increased psychophysiological reactivity is a hallmark intermediate phenotype of posttraumatic stress disorder (PTSD). Individuals with PTSD exhibit greater skin conductance (SC) responses to trauma scripts than trauma survivors without PTSD. However, trauma scripts require time for development and cannot be...

journal_title：Depression and anxiety

authors： Hinrichs R,Michopoulos V,Winters S,Rothbaum AO,Rothbaum BO,Ressler KJ,Jovanovic T

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Oligodendrocyte transcription factor 2 (OLIG2) is primarily concentrated in the brain and spinal cord ventricular zone, where this protein stimulates oligodendrocytes and specific neurons, determines motor neuron and oligodendrocyte differentiation, and sustains replication in early development. Recent studi...

journal_title：Depression and anxiety

authors： Zhang X,Liu J,Guo Y,Jiang W,Yu J

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:An issue of critical importance for psychiatry and women's health is whether postpartum depression (PPD) represents a unique condition. The Diagnostic and Statistical Manual of Mental Disorders asserts that major depressive disorder (MDD) may present with peripartum onset, without suggesting any other differ...

journal_title：Depression and anxiety

authors： Fox M,Sandman CA,Davis EP,Glynn LM

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:We used a dot-probe paradigm to examine attention bias toward threat (i.e., angry) and happy face stimuli in severe mood dysregulation (SMD) versus healthy comparison (HC) youth. The tendency to allocate attention to threat is well established in anxiety and other disorders of negative affect. SMD is charact...

journal_title：Depression and anxiety

authors： Hommer RE,Meyer A,Stoddard J,Connolly ME,Mogg K,Bradley BP,Pine DS,Leibenluft E,Brotman MA

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Treatment utilization/costs and work performance for persons with major depressive disorder (MDD) by severity of illness is not well documented. METHODS:Using National Comorbidity Survey-Replication (2001-2002) data, US workforce respondents (n=4,465) were classified by clinical severity (not clinically dep...

journal_title：Depression and anxiety

authors： Birnbaum HG,Kessler RC,Kelley D,Ben-Hamadi R,Joish VN,Greenberg PE

更新日期：2010-01-01 00:00:00

abstract：:It is well known that insomnia is more frequent in women than in men throughout all age groups. In this respect insomnia resembles other psychiatric disorders that occur more frequently in women such as anxiety and depressive disorders. Since insomnia is frequently a symptom of anxiety and depression, it remains an op...

journal_title：Depression and anxiety

authors： Voderholzer U,Al-Shajlawi A,Weske G,Feige B,Riemann D

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Generalized anxiety disorder (GAD) is a common and sometimes disabling condition often associated with stressful life events that involve significant loss or danger. The disorder appears moderately heritable. Polymorphisms in the RGS2 (regulator of G-protein signaling 2) gene were recently associated with an...

journal_title：Depression and anxiety

authors： Koenen KC,Amstadter AB,Ruggiero KJ,Acierno R,Galea S,Kilpatrick DG,Gelernter J

更新日期：2009-01-01 00:00:00

abstract：:There are well-established sex differences in the prevalence of certain mental disorders. Work in animal models has provided us with an emerging understanding of the role that epigenetic factors play in establishing sex differences in the brain during development. Similarly, work in animal models, and a more limited b...

journal_title：Depression and anxiety

authors： Uddin M,Sipahi L,Li J,Koenen KC

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:There is ample evidence of the efficacy of cognitive-behavioral therapy (CBT) for depression in adolescents, including Puerto Rican adolescents. However, there is still a high percentage of adolescents who do not respond to a standard "dose" of 12 sessions of CBT. This clinical case study explores the charac...

journal_title：Depression and anxiety

authors： Jiménez Chafey MI,Bernal G,Rosselló J

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Major depressive disorder (MDD) has been associated with changes in mean telomere length and mitochondrial DNA (mtDNA) copy number. This study investigates if clinical features of MDD differentially impact these molecular markers. METHODS:Data from a large, clinically ascertained sample of Han Chinese women...

journal_title：Depression and anxiety

authors： Edwards AC,Aggen SH,Cai N,Bigdeli TB,Peterson RE,Docherty AR,Webb BT,Bacanu SA,Flint J,Kendler KS

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Understanding cognitive and biological mechanisms of PTSD treatment can help refine treatments and increase rates of response. METHODS:Thirty-six veterans with PTSD were randomly assigned to receive Prolonged exposure therapy (PE) or Present-Centered therapy (PCT). We examined symptoms, trauma-related cogni...

journal_title：Depression and anxiety

authors： Rauch SA,King AP,Abelson J,Tuerk PW,Smith E,Rothbaum BO,Clifton E,Defever A,Liberzon I

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Bipolar disorder (BD) is highly familial, but studies have yet to examine preschoolers at risk for BD using standardized, developmentally appropriate clinical assessment tools. We used such methods to test whether preschoolers at familial risk for BD have more observed difficulty modulating emotions and beha...

journal_title：Depression and anxiety

authors： Tseng WL,Guyer AE,Briggs-Gowan MJ,Axelson D,Birmaher B,Egger HL,Helm J,Stowe Z,Towbin KA,Wakschlag LS,Leibenluft E,Brotman MA

更新日期：2015-05-01 00:00:00

abstract：:This study explores the psychometric properties of the Portuguese version of Corah's Dental Anxiety Scale (DAS), an instrument designed to assess the manifestations of dental anxiety. The DAS has been translated into several languages, but no adaptation and reliability analysis of the Portuguese version of the scale h...

journal_title：Depression and anxiety

authors： Hu LW,Gorenstein C,Fuentes D

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Acute stress disorder (ASD) predicts the development of posttraumatic stress disorder (PTSD), which in some sufferers can persist for years and lead to significant disability. We carried out a review of randomized controlled trials to give an update on which psychological treatments are empirically supported...

journal_title：Depression and anxiety

authors： Ponniah K,Hollon SD

更新日期：2009-01-01 00:00:00

abstract：:In this analysis we examined studies of tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) to compare efficacy and drop-out rates. Frequency of reported side effects was also studied. Using Medline, we located 36 clinical trials of TCAs and SSRIs in a double-blind comparison. We perfo...

journal_title：Depression and anxiety

authors： Steffens DC,Krishnan KR,Helms MJ

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Synchronized transcranial magnetic stimulation (sTMS) is a new modality to reduce symptoms of major depressive disorder (MDD). sTMS uses rotating neodymium magnets to deliver low-field stimulation matched to the individual alpha frequency (IAF). A previous multisite study showed that sTMS significantly reduc...

journal_title：Depression and anxiety

authors： Philip NS,Leuchter AF,Cook IA,Massaro J,Goethe JW,Carpenter LL

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Adolescent suicide attempts are disproportionally prevalent and frequently of low severity, raising questions regarding their long-term prognostic implications. In this study, we examined whether adolescent attempts were associated with impairments related to suicidality, psychopathology, and psychosocial fu...

journal_title：Depression and anxiety

authors： Brière FN,Rohde P,Seeley JR,Klein D,Lewinsohn PM

更新日期：2015-04-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is a clinically heterogeneous disorder; nonetheless, most of the previous neuropsychological studies for assessing the involvement of memory dysfunction grouped together patients with different symptoms, thereby potentially accounting for the inconsistencies of results. The goals of...

journal_title：Depression and anxiety

authors： Cha KR,Koo MS,Kim CH,Kim JW,Oh WJ,Suh HS,Lee HS

更新日期：2008-01-01 00:00:00

abstract：:Depressive symptoms, due either major depression or clinically significant, subsyndromal depression, occur commonly in the course of Alzheimer's disease. For a variety of clinical and methodological reasons, this remains an area that begs for new investigation. At the very least, these depressive symptoms should be vi...

journal_title：Depression and anxiety

authors： Tune LE

更新日期：1998-01-01 00:00:00

abstract：:The objective was to present naturalistic 1-year follow-up information of 96 child and adolescent outpatients with major depressive disorder who had been randomized in an 8-week double-blind, placebo-controlled trial of fluoxetine. Subjects were children and adolescents, ages 8-18 years, who were entered in a randomiz...

journal_title：Depression and anxiety

authors： Emslie GJ,Rush AJ,Weinberg WA,Kowatch RA,Carmody T,Mayes TL

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:The role of the neuropeptide oxytocin (OT) in Borderline Personality Disorder (BPD) is poorly understood. It is particularly unknown how early experiences with caregivers moderate the action of OT in BPD. Here, we examined the association of plasma OT levels in BPD patients with the experience of c...

journal_title：Depression and anxiety

authors： Ebert A,Edel MA,Gilbert P,Brüne M

更新日期：2018-01-01 00:00:00

abstract：:The selective serotonin reuptake inhibitors (SSRIs) are recognized as effective as and better tolerated than older antidepressant therapies and have become the drugs of choice in the treatment of mild to moderate depression. However, there is a clinical impression that the SSRIs are less effective than older therapies...

journal_title：Depression and anxiety

authors： Schatzberg AF

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Amygdala-prefrontal cortex (PFC) functional connectivity may be influenced by anxiety and development. A prior study on anxiety found age-specific dysfunction in the ventromedial PFC (vmPFC), but not amygdala, associated with threat-safety discrimination during extinction recall (Britton et al.). However, tr...

journal_title：Depression and anxiety

authors： Gold AL,Shechner T,Farber MJ,Spiro CN,Leibenluft E,Pine DS,Britton JC

更新日期：2016-10-01 00:00:00

abstract：:This study provides a focused review of issues that are relevant to the nosology of the tic disorders and presents preliminary recommendations to be considered for DSM-V. The recommended changes are designed to clarify and simplify the diagnostic criteria, reduce the use of the residual category, tic disorder not othe...

journal_title：Depression and anxiety

authors： Walkup JT,Ferrão Y,Leckman JF,Stein DJ,Singer H

更新日期：2010-06-01 00:00:00

abstract：:Depressed patients who rapidly metabolize antidepressants may be common, and may not respond to even high doses of antidepressants if subtherapeutic plasma levels are produced. Rapid metabolizers (RMs) are identifiable if patients are on tricyclic antidepressants (TCAs), and TCA plasma levels (commonly available) are ...

journal_title：Depression and anxiety

authors： Kraus RP,Diaz P,McEachran A

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Diagnostic criteria for DSM-5 posttraumatic stress disorder (PTSD) are in many ways similar to DSM-IV criteria, raising the possibility that it might be possible to closely approximate DSM-5 diagnoses using DSM-IV symptoms. If so, the resulting transformation rules could be used to pool research data based o...

journal_title：Depression and anxiety

authors： Rosellini AJ,Stein MB,Colpe LJ,Heeringa SG,Petukhova MV,Sampson NA,Schoenbaum M,Ursano RJ,Kessler RC,Army STARRS Collaborators.

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Many individuals with obsessive-compulsive disorder (OCD) do not receive professional treatment due to various idiosyncratic barriers. Internet-based cognitive-behavioral therapy (iCBT) is increasingly used to narrow treatment gaps, but the efficacy of such interventions without guidance of therapists has no...

journal_title：Depression and anxiety

authors： Schröder J,Werkle N,Cludius B,Jelinek L,Moritz S,Westermann S

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:A significant proportion of soldiers return from deployment with symptoms of fatigue, sleep difficulties, and posttraumatic complaints. Disrupted sleep has been proposed as a contributing factor for the development of posttraumatic stress disorder (PTSD). This study investigates the impact of impaired sleep ...

journal_title：Depression and anxiety

authors： van Liempt S,van Zuiden M,Westenberg H,Super A,Vermetten E

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Complicated grief (CG) is a bereavement-specific syndrome characterized by traumatic and separation distress lasting over 6 months. Little is known about the role of dissociation experienced during or immediately after the loss of a loved one (i.e., periloss dissociation [PLD]) in CG. The present study aimed...

journal_title：Depression and anxiety

authors： Bui E,Simon NM,Robinaugh DJ,Leblanc NJ,Wang Y,Skritskaya NA,Mauro C,Shear MK

更新日期：2013-02-01 00:00:00

abstract：:Despite emotion regulation being altered in patients with obsessive-compulsive disorder (OCD), no studies have investigated its relation to multimodal amygdala connectivity. We compared corticolimbic functional and structural connectivity between OCD patients and healthy controls (HCs), and correlated this with the di...

journal_title：Depression and anxiety

authors： Picó-Pérez M,Ipser J,Taylor P,Alonso P,López-Solà C,Real E,Segalàs C,Roos A,Menchón JM,Stein DJ,Soriano-Mas C

更新日期：2019-02-01 00:00:00