Protein synthesis inhibition before or after stress exposure results in divergent endocrine and BDNF responses disassociated from behavioral responses.

abstract：BACKGROUND:The significance of the timing and chronicity of childhood adversity for depression outcomes later in life is unclear. Identifying trajectories of adversity throughout childhood would allow classification of children according to the accumulation, timing, and persistence of adversity, and may provide unique ...

journal_title：Depression and anxiety

authors： Tracy M,Salo M,Slopen N,Udo T,Appleton AA

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Increased psychophysiological reactivity is a hallmark intermediate phenotype of posttraumatic stress disorder (PTSD). Individuals with PTSD exhibit greater skin conductance (SC) responses to trauma scripts than trauma survivors without PTSD. However, trauma scripts require time for development and cannot be...

journal_title：Depression and anxiety

authors： Hinrichs R,Michopoulos V,Winters S,Rothbaum AO,Rothbaum BO,Ressler KJ,Jovanovic T

更新日期：2017-06-01 00:00:00

abstract：:Sleep deprivation for one night has been investigated as a treatment for depression since the first publications describing its antidepressant properties almost 30 years ago [Pflug and Tolle, 1971: Int Pharmacopsychiatry 6:187-196]. It remains a field of active research. It is the only intervention consistently demons...

journal_title：Depression and anxiety

authors： Ringel BL,Szuba MP

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Self-esteem is a major concern in mood disorders. Low self-esteem is a symptom of depressive disorders and is considered by some to be a predictor for relapse, whereas high self-esteem seems to buffer against depression. Recently, Competitive Memory Training (COMET) has shown to be effective for the enhancem...

journal_title：Depression and anxiety

authors： Korrelboom K,Maarsingh M,Huijbrechts I

更新日期：2012-02-01 00:00:00

abstract：:This study replicated the factor structure of the Parental Bonding Instrument (PBI), and explored the relationships of PBI scores to demographic variables. We investigated the association between parental bonding in the parents measured by the PBI, and lifetime history of depression in their children assessed by the I...

journal_title：Depression and anxiety

authors： Uehara T,Sato T,Sakado K,Someya T

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Psychiatrists frequently struggle with how to sequence treatment for depressed adolescents who do not respond to an adequate trial of a selective serotonin reuptake inhibitor (SSRI). This study leveraged recent statistical and computational advances to create Bayesian hierarchal models (BHMs) of response in ...

journal_title：Depression and anxiety

authors： Suresh V,Mills JA,Croarkin PE,Strawn JR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Individuals with depression may not seek treatment for their symptoms due to several types of barriers to treatment. In support of the growing research on mental health care access and the role of social media, this study aimed to increase knowledge of these barriers among social media users. METHODS:Partic...

journal_title：Depression and anxiety

authors： Szlyk H,Deng J,Xu C,Krauss MJ,Cavazos-Rehg PA

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Depression and anxiety have been related to poorer self-reported physical functioning over time; however, objective measures of physical function are less frequently examined. This study assessed the 6-year trajectory of hand-grip strength and lung function in persons with depressive and/or anxiety disorders...

journal_title：Depression and anxiety

authors： Lever-van Milligen BA,Lamers F,Smit JH,Penninx BW

更新日期：2017-02-01 00:00:00

abstract：:Memory function was studied in combat veterans with posttraumatic stress disorder (PTSD), combat veterans without PTSD, and noncombat veterans. The Vocabulary and Digit Span subtests of the WAIS and Logical Memory (LMS) and Verbal Paired Associates (VPAS) subtests of the Wechsler Memory Scale III were administered. Co...

journal_title：Depression and anxiety

authors： Burriss L,Ayers E,Ginsberg J,Powell DA

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:There is evidence that negative affect (NA) and anxiety sensitivity (AS) predict the development of anxiety disorders, particularly panic disorder (PD). The main purpose of this study was to examine whether NA and AS will also predict the clinical course of PD. METHODS:Participants were 136 individuals with...

journal_title：Depression and anxiety

authors： Benítez CI,Shea MT,Raffa S,Rende R,Dyck IR,Ramsawh HJ,Edelen MO,Keller MB

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Brain structures underlying posttraumatic stress disorder (PTSD) have been a focus of imaging studies, but associations between treatment outcome and alterations in brain structures remain largely unexamined. We longitudinally examined the relation of structural changes in the rostral anterior cingulate cort...

journal_title：Depression and anxiety

authors： Helpman L,Papini S,Chhetry BT,Shvil E,Rubin M,Sullivan GM,Markowitz JC,Mann JJ,Neria Y

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Acute stress disorder (ASD) predicts the development of posttraumatic stress disorder (PTSD), which in some sufferers can persist for years and lead to significant disability. We carried out a review of randomized controlled trials to give an update on which psychological treatments are empirically supported...

journal_title：Depression and anxiety

authors： Ponniah K,Hollon SD

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Many individuals with obsessive-compulsive disorder (OCD) do not receive professional treatment due to various idiosyncratic barriers. Internet-based cognitive-behavioral therapy (iCBT) is increasingly used to narrow treatment gaps, but the efficacy of such interventions without guidance of therapists has no...

journal_title：Depression and anxiety

authors： Schröder J,Werkle N,Cludius B,Jelinek L,Moritz S,Westermann S

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Bipolar disorder (BD) is highly familial, but studies have yet to examine preschoolers at risk for BD using standardized, developmentally appropriate clinical assessment tools. We used such methods to test whether preschoolers at familial risk for BD have more observed difficulty modulating emotions and beha...

journal_title：Depression and anxiety

authors： Tseng WL,Guyer AE,Briggs-Gowan MJ,Axelson D,Birmaher B,Egger HL,Helm J,Stowe Z,Towbin KA,Wakschlag LS,Leibenluft E,Brotman MA

更新日期：2015-05-01 00:00:00

abstract：:Research has shown that obsessive compulsive disorder (OCD) is related to structural and functional abnormalities in the brain, and several authors have organized these findings into theories of OCD neuropsychiatric dysfunction. In this paper, these theories were used to develop a neural network model of OCD. OCD symp...

journal_title：Depression and anxiety

authors： Ownby RL

更新日期：1998-01-01 00:00:00

abstract：:Acute grief is emotionally intense, cognitively preoccupying, and disruptive, but grief is not an illness; major depression and anxiety disorders are. Grief and mourning have a purpose. They provide an intense, focused opportunity to reregulate emotion and to engage in a learning process that is aimed at reconfiguring...

journal_title：Depression and anxiety

authors： Shear MK

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Controversy surrounds the question of whether agoraphobia (AG) exists as an independent diagnostic entity apart from panic. In favor of this position, AG without panic disorder (PD) in parents was found being unrelated to offsprings' risk for AG or PD, albeit it may enhance the familial transmission of PD (N...

journal_title：Depression and anxiety

authors： Knappe S,Beesdo-Baum K,Nocon A,Wittchen HU

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Understanding cognitive and biological mechanisms of PTSD treatment can help refine treatments and increase rates of response. METHODS:Thirty-six veterans with PTSD were randomly assigned to receive Prolonged exposure therapy (PE) or Present-Centered therapy (PCT). We examined symptoms, trauma-related cogni...

journal_title：Depression and anxiety

authors： Rauch SA,King AP,Abelson J,Tuerk PW,Smith E,Rothbaum BO,Clifton E,Defever A,Liberzon I

更新日期：2015-03-01 00:00:00

abstract：:The American Psychiatric Association and the World Health Organization have begun to revise their classifications of mental disorders. Four issues related to these revisions are discussed in this study: the structure of the classifications, the relationship between categories and dimensions, the sensitivity of categor...

journal_title：Depression and anxiety

authors： Andrews G,Anderson TM,Slade T,Sunderland M

更新日期：2008-01-01 00:00:00

abstract：:Obsessive-compulsive disorder (OCD) is a clinically heterogeneous disorder; nonetheless, most of the previous neuropsychological studies for assessing the involvement of memory dysfunction grouped together patients with different symptoms, thereby potentially accounting for the inconsistencies of results. The goals of...

journal_title：Depression and anxiety

authors： Cha KR,Koo MS,Kim CH,Kim JW,Oh WJ,Suh HS,Lee HS

更新日期：2008-01-01 00:00:00

abstract：:Data from early studies of selective serotonin reuptake inhibitors have shown that these agents are effective in the treatment of social anxiety disorder (social phobia). This review highlights the outcomes of three large clinical trials of paroxetine in patients with social anxiety disorder. In two of the studies, pa...

journal_title：Depression and anxiety

authors： Lydiard RB,Bobes J

更新日期：2000-01-01 00:00:00

abstract：:This study provides a focused review of issues that are relevant to the nosology of the tic disorders and presents preliminary recommendations to be considered for DSM-V. The recommended changes are designed to clarify and simplify the diagnostic criteria, reduce the use of the residual category, tic disorder not othe...

journal_title：Depression and anxiety

authors： Walkup JT,Ferrão Y,Leckman JF,Stein DJ,Singer H

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Diagnostic criteria for DSM-5 posttraumatic stress disorder (PTSD) are in many ways similar to DSM-IV criteria, raising the possibility that it might be possible to closely approximate DSM-5 diagnoses using DSM-IV symptoms. If so, the resulting transformation rules could be used to pool research data based o...

journal_title：Depression and anxiety

authors： Rosellini AJ,Stein MB,Colpe LJ,Heeringa SG,Petukhova MV,Sampson NA,Schoenbaum M,Ursano RJ,Kessler RC,Army STARRS Collaborators.

更新日期：2015-07-01 00:00:00

abstract：:The use of a placebo run-in phase, in which placebo responders are withdrawn from a study before random assignment to treatment condition, has been criticized as favoring the active treatment in clinical trials. We compared the effect size of randomized, placebo-controlled clinical trials (in the treatment of depressi...

journal_title：Depression and anxiety

authors： Lee S,Walker JR,Jakul L,Sexton K

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The clinical presentation of panic disorder (PD) is known to be highly heterogeneous, complicating research on its etiology, neurobiological pathways, and treatment. None of the attempts to identify PD subtypes have been independently reproduced, rendering the current literature inconclusive. METHODS:Using ...

journal_title：Depression and anxiety

authors： Pattyn T,Van Den Eede F,Lamers F,Veltman D,Sabbe BG,Penninx BW

更新日期：2015-07-01 00:00:00

abstract：:There is an urgent need for more rapidly effective pharmacotherapies for major depressive disorder and bipolar disorder (BP) that are efficacious and tolerable for depressed patients who respond poorly to conventional treatments. Multiple controlled trials have now demonstrated a rapid, nonsustained antidepressive res...

journal_title：Depression and anxiety

authors： Bobo WV,Vande Voort JL,Croarkin PE,Leung JG,Tye SJ,Frye MA

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Adolescent suicide attempts are disproportionally prevalent and frequently of low severity, raising questions regarding their long-term prognostic implications. In this study, we examined whether adolescent attempts were associated with impairments related to suicidality, psychopathology, and psychosocial fu...

journal_title：Depression and anxiety

authors： Brière FN,Rohde P,Seeley JR,Klein D,Lewinsohn PM

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Oligodendrocyte transcription factor 2 (OLIG2) is primarily concentrated in the brain and spinal cord ventricular zone, where this protein stimulates oligodendrocytes and specific neurons, determines motor neuron and oligodendrocyte differentiation, and sustains replication in early development. Recent studi...

journal_title：Depression and anxiety

authors： Zhang X,Liu J,Guo Y,Jiang W,Yu J

更新日期：2015-10-01 00:00:00

abstract：:Treatment-resistant depression (TRD) in adolescents is prevalent and impairing. We here review the definition, prevalence, clinical significance, risk factors, and management of TRD in adolescents. Risk factors associated with TRD include characteristics of depression (severity, level of hopelessness, and suicidal ide...

journal_title：Depression and anxiety

authors： Maalouf FT,Atwi M,Brent DA

更新日期：2011-11-01 00:00:00

abstract：:Dopamine D(2) receptor availability in the striatum has been reported to be low in generalized social anxiety disorder (GSAD) and obsessive-compulsive disorder (OCD), but it has not been studied in persons with comorbid OCD and GSAD (OCD+GSAD). D(2) receptor availability was assessed in 7 subjects with OCD+GSAD, 8 wit...

journal_title：Depression and anxiety

authors： Schneier FR,Martinez D,Abi-Dargham A,Zea-Ponce Y,Simpson HB,Liebowitz MR,Laruelle M

更新日期：2008-01-01 00:00:00