Adolescent suicide attempts and adult adjustment.

abstract：BACKGROUND:To elucidate mechanisms related to remission in winter seasonal affective disorder (SAD), we explored the course of individual depressive symptom offset across two distinct treatment modalities that show comparable outcomes at treatment endpoint: cognitive-behavioral therapy for SAD (CBT-SAD) and light thera...

journal_title：Depression and anxiety

authors： Meyerhoff J,Young MA,Rohan KJ

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Few studies have longitudinally examined predictors of posttraumatic stress disorder (PTSD) in a nationally representative sample of US veterans. We examined predictors of warzone-related PTSD over a 25-year span using data from the National Vietnam Veterans Longitudinal Study (NVVLS). METHODS:The NVVLS is ...

journal_title：Depression and anxiety

authors： Steenkamp MM,Schlenger WE,Corry N,Henn-Haase C,Qian M,Li M,Horesh D,Karstoft KI,Williams C,Ho CL,Shalev A,Kulka R,Marmar C

更新日期：2017-08-01 00:00:00

abstract：:This study was designed to investigate the efficacy of the antidepressant fluvoxamine in the treatment of combat-related post-traumatic stress disorder (PTSD). Fifteen veterans with combat-related PTSD and no other psychiatric diagnosis except depression were recruited to participate in a 14-week open-label study of f...

journal_title：Depression and anxiety

authors： Escalona R,Canive JM,Calais LA,Davidson JR

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:In previous reports from the Rhode Island Methods to Improve Diagnostic Assessment and Services project, we developed a briefer definition of major depressive disorder (MDD), and found high levels of agreement between the simplified and DSM-IV definitions of MDD. The goal of the present study was to examine ...

journal_title：Depression and anxiety

authors： Zimmerman M,Galione JN,Chelminski I,Young D,Dalrymple K,Witt CF

更新日期：2010-10-01 00:00:00

abstract：:Internet-delivered cognitive behavioral therapy (iCBT) was developed to overcome some of the barriers in accessing best practice face-to-face CBT. iCBT affords many benefits, such as high fidelity, greater accessibility, convenience, and reduced cost to patients and health-care systems. Recent meta-analyses of iCBT fo...

journal_title：Depression and anxiety

authors： Andrews G,Williams AD

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Depression outcomes in research and clinical practice are commonly defined by the concepts of remission, recovery, relapse, and recurrence. Despite their widespread use, there has been little empirical examination of these concepts. Therefore, we investigated profiles of individual symptoms during each of th...

journal_title：Depression and anxiety

authors： Conradi HJ,Ormel J,de Jonge P

更新日期：2012-07-01 00:00:00

abstract：:Depressed patients who rapidly metabolize antidepressants may be common, and may not respond to even high doses of antidepressants if subtherapeutic plasma levels are produced. Rapid metabolizers (RMs) are identifiable if patients are on tricyclic antidepressants (TCAs), and TCA plasma levels (commonly available) are ...

journal_title：Depression and anxiety

authors： Kraus RP,Diaz P,McEachran A

更新日期：1996-01-01 00:00:00

abstract：:In spite of substantial advances in the treatment of major depression by pharmacotherapy and other means, a significant number of depressed patients require hospitalization. In the context of the Jerusalem Collaborative Depression Project, possible precipitants of psychiatric hospitalization were sought in a cohort of...

journal_title：Depression and anxiety

authors： Lerer B,Shapira B,Bloch M,Hanin B,Trudart T,Alexander JR,Popper M,Braun D,Segman RH,Ritsner M

更新日期：1999-01-01 00:00:00

abstract：:Dopamine D(2) receptor availability in the striatum has been reported to be low in generalized social anxiety disorder (GSAD) and obsessive-compulsive disorder (OCD), but it has not been studied in persons with comorbid OCD and GSAD (OCD+GSAD). D(2) receptor availability was assessed in 7 subjects with OCD+GSAD, 8 wit...

journal_title：Depression and anxiety

authors： Schneier FR,Martinez D,Abi-Dargham A,Zea-Ponce Y,Simpson HB,Liebowitz MR,Laruelle M

更新日期：2008-01-01 00:00:00

abstract：:Serotonergic (5-hydroxytryptamine; 5-HT) mechanisms have been implicated in a number of physiological and pathophysiological processes including mood, anxiety, and cognitive functioning. Among the many 5-HT receptor subtypes, the 5-HT2A receptors (5-HT2A-R) seem to be of particular importance in mediating these effect...

journal_title：Depression and anxiety

authors： Cohen H

更新日期：2005-01-01 00:00:00

abstract：:There is abundant evidence for abnormalities of the norepinephrine (NE) and serotonin (5HT) neurotransmitter systems in depression and anxiety disorders. The majority of evidence supports underactivation of serotonergic function and complex dysregulation of noradrenergic function, most consistent with overactivation o...

journal_title：Depression and anxiety

authors： Ressler KJ,Nemeroff CB

更新日期：2000-01-01 00:00:00

abstract：:Pediatric psychopharmacology is hindered by the relative lack of controlled, empirical clinical trials [Shatzberg and Nemeroff, 1998: Washington, D.C.: The American Psychiatric Press, Inc. p 301-306]. Psychiatric disorders in children and adolescents carry considerable morbidity, impede development, and carry a signif...

journal_title：Depression and anxiety

authors： Weller EB,Weller RA,Davis GP

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Depression and anxiety have been related to poorer self-reported physical functioning over time; however, objective measures of physical function are less frequently examined. This study assessed the 6-year trajectory of hand-grip strength and lung function in persons with depressive and/or anxiety disorders...

journal_title：Depression and anxiety

authors： Lever-van Milligen BA,Lamers F,Smit JH,Penninx BW

更新日期：2017-02-01 00:00:00

abstract：:Participants with generalized social phobia (GSP) with (n=36) and without (n=19) avoidant personality disorder (AVPD) were compared via contrasts of group means and classification analysis on purported core features of AVPD. GSP-AVPD participants proved to be more severely impaired or distressed on some group contrast...

journal_title：Depression and anxiety

authors： Chambless DL,Fydrich T,Rodebaugh TL

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Investigations of gene-environment interaction (GxE) in depression have implicated a polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) as a moderator of the stress-depression relationship. However, recent evidence for 5-HTTLPR GxE in depression has been inconsistent. This study...

journal_title：Depression and anxiety

authors： Conway CC,Hammen C,Brennan PA,Lind PA,Najman JM

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVE:To compare the rates of low birth weight, preterm delivery and small for gestational age (SGA), in pregnancy outcomes among women who were exposed and nonexposed to antidepressants during pregnancy. METHODS:At The Motherisk Program, we analyzed pregnancy outcomes of 1,243 women in our database who took vario...

journal_title：Depression and anxiety

authors： Einarson A,Choi J,Einarson TR,Koren G

更新日期：2010-01-01 00:00:00

abstract：:We successfully treated a 46-year-old narcoleptic woman suffering from atypical depression with bupropion hydrochloride. Diagnostic evaluation revealed a Beck Depression Inventory (BDI) score of 24, a short nocturnal REM-sleep latency, subjective and objective sleepiness (mean sleep latency (MSL) = 1.8 minutes), and t...

journal_title：Depression and anxiety

authors： Rye DB,Dihenia B,Bliwise DL

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Complicated grief (CG) is a bereavement-specific syndrome characterized by traumatic and separation distress lasting over 6 months. Little is known about the role of dissociation experienced during or immediately after the loss of a loved one (i.e., periloss dissociation [PLD]) in CG. The present study aimed...

journal_title：Depression and anxiety

authors： Bui E,Simon NM,Robinaugh DJ,Leblanc NJ,Wang Y,Skritskaya NA,Mauro C,Shear MK

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Pathological avoidance is a transdiagnostic characteristic of anxiety disorders. Avoidance conditioning re-emerged as a translational model to examine mechanisms and treatment of avoidance. However, its validity for anxiety disorders remains unclear. METHODS:This study tested for altered avoidance in patien...

journal_title：Depression and anxiety

authors： Pittig A,Boschet JM,Glück VM,Schneider K

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Brain structures underlying posttraumatic stress disorder (PTSD) have been a focus of imaging studies, but associations between treatment outcome and alterations in brain structures remain largely unexamined. We longitudinally examined the relation of structural changes in the rostral anterior cingulate cort...

journal_title：Depression and anxiety

authors： Helpman L,Papini S,Chhetry BT,Shvil E,Rubin M,Sullivan GM,Markowitz JC,Mann JJ,Neria Y

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Previous work has shown that inhibition of fear is impaired in posttraumatic stress disorder (PTSD) resulting from both civilian and combat trauma. The purpose of the present study was to investigate the inhibition of learned fear in traumatized individuals diagnosed with either acute stress disorder (ASD) o...

journal_title：Depression and anxiety

authors： Jovanovic T,Sakoman AJ,Kozarić-Kovačić D,Meštrović AH,Duncan EJ,Davis M,Norrholm SD

更新日期：2013-03-01 00:00:00

abstract：:It is well known that insomnia is more frequent in women than in men throughout all age groups. In this respect insomnia resembles other psychiatric disorders that occur more frequently in women such as anxiety and depressive disorders. Since insomnia is frequently a symptom of anxiety and depression, it remains an op...

journal_title：Depression and anxiety

authors： Voderholzer U,Al-Shajlawi A,Weske G,Feige B,Riemann D

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Understanding cognitive and biological mechanisms of PTSD treatment can help refine treatments and increase rates of response. METHODS:Thirty-six veterans with PTSD were randomly assigned to receive Prolonged exposure therapy (PE) or Present-Centered therapy (PCT). We examined symptoms, trauma-related cogni...

journal_title：Depression and anxiety

authors： Rauch SA,King AP,Abelson J,Tuerk PW,Smith E,Rothbaum BO,Clifton E,Defever A,Liberzon I

更新日期：2015-03-01 00:00:00

abstract：:Progestational hormones may have anxiolytic properties. CCK-4 (cholecystokinin tetrapeptide) can be used pharmacologically to induce panic attacks both in normal controls and patients suffering from panic disorder. In this study we compared the effects of pretreatment with the progestational hormone megestrol and plac...

journal_title：Depression and anxiety

authors： Raedler TJ,Jahn H,Goedeken B,Gescher DM,Kellner M,Wiedemann K

更新日期：2006-01-01 00:00:00

abstract：:Given the high rates of maladjustment among children of depressed mothers, parenting is likely to cause significant life stress in this population, potentially worsening the course of mothers' depression. The present study is a comparison of severe life stress in 38 mothers and 62 non-mothers receiving treatment for r...

journal_title：Depression and anxiety

authors： Feske U,Shear MK,Anderson B,Cyranowski J,Strassburger M,Matty M,Luther J,Frank E

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Childhood maltreatment has been associated with symptom severity, reduced quality of life, and impaired functioning in adults with social anxiety disorder (SAD). No study has investigated how childhood maltreatment impacts pharmacotherapy outcomes in this population, despite evidence for such a link in depre...

journal_title：Depression and anxiety

authors： Bruce LC,Heimberg RG,Blanco C,Schneier FR,Liebowitz MR

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Psychiatrists frequently struggle with how to sequence treatment for depressed adolescents who do not respond to an adequate trial of a selective serotonin reuptake inhibitor (SSRI). This study leveraged recent statistical and computational advances to create Bayesian hierarchal models (BHMs) of response in ...

journal_title：Depression and anxiety

authors： Suresh V,Mills JA,Croarkin PE,Strawn JR

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Oligodendrocyte transcription factor 2 (OLIG2) is primarily concentrated in the brain and spinal cord ventricular zone, where this protein stimulates oligodendrocytes and specific neurons, determines motor neuron and oligodendrocyte differentiation, and sustains replication in early development. Recent studi...

journal_title：Depression and anxiety

authors： Zhang X,Liu J,Guo Y,Jiang W,Yu J

更新日期：2015-10-01 00:00:00

abstract：:This study examined sex differences in the use of coping strategies and their relationship to depression and anxiety-related psychopathology. Responses on measures of coping strategies, depression, and anxiety were obtained from a carefully screened nonclinical sample (N = 107). The results demonstrated that women who...

journal_title：Depression and anxiety

authors： Kelly MM,Tyrka AR,Price LH,Carpenter LL

更新日期：2008-01-01 00:00:00

abstract：:The use of a placebo run-in phase, in which placebo responders are withdrawn from a study before random assignment to treatment condition, has been criticized as favoring the active treatment in clinical trials. We compared the effect size of randomized, placebo-controlled clinical trials (in the treatment of depressi...

journal_title：Depression and anxiety

authors： Lee S,Walker JR,Jakul L,Sexton K

更新日期：2004-01-01 00:00:00