Potential mechanisms of the sleep therapies for depression.

Abstract:

:Sleep deprivation for one night has been investigated as a treatment for depression since the first publications describing its antidepressant properties almost 30 years ago [Pflug and Tolle, 1971: Int Pharmacopsychiatry 6:187-196]. It remains a field of active research. It is the only intervention consistently demonstrated to produce next-day antidepressant results. This makes sleep deprivation an exciting and unique tool to study the pathophysiology of depressive disorders and to formulate targets for novel antidepressant agents. Importantly, it is also an effective, but underused, clinical treatment for unipolar and bipolar depression.

journal_name

Depress Anxiety

journal_title

Depression and anxiety

authors

Ringel BL,Szuba MP

doi

10.1002/da.1044

subject

Has Abstract

pub_date

2001-01-01 00:00:00

pages

29-36

issue

1

eissn

1091-4269

issn

1520-6394

pii

10.1002/da.1044

journal_volume

14

pub_type

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