Abstract:
:A reclassification of obsessive-compulsive disorder (OCD) into a new diagnostic category spectrum of "obsessive-compulsive spectrum disorders" (OCSDs) has recently been proposed, with considerable debate, for the forthcoming Diagnostic and Statistical Manual-Fifth Edition (DSM-V). This paper provides a critical analysis of the available empirical data regarding this conceptual and nosological shift. Specifically, we review research on shared commonalities and differences between OCD and the putative OCSDs in relation to their clinical presentation, phenotype, neurobiology, and treatment response. We conclude that a reclassification of OCD into a separate OCSD spectrum is premature and not supported by the currently available data.
journal_name
Depress Anxietyjournal_title
Depression and anxietyauthors
Storch EA,Abramowitz J,Goodman WKdoi
10.1002/da.20488subject
Has Abstractpub_date
2008-01-01 00:00:00pages
336-47issue
4eissn
1091-4269issn
1520-6394journal_volume
25pub_type
杂志文章,评审abstract:BACKGROUND:Anticipatory anxiety can be described as a conditioned response with a defensive posture of freezing and autonomic activation. The purpose of this study was to assess the postural control analysis and autonomic activation in panic disorder (PD) patients presented with visual stimuli. METHODS:PD patients (n=...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20593
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:The present trial was designed to assess the efficacy and safety of escitalopram prescribed to patients seeking treatment of major depressive disorder (MDD) in a Canadian primary-care setting. METHODS:Investigators (mainly primary-care physicians) enrolled patients with MDD from their daily practice. Patien...
journal_title:Depression and anxiety
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/da.20458
更新日期:2008-01-01 00:00:00
abstract::This study was designed to investigate the efficacy of the antidepressant fluvoxamine in the treatment of combat-related post-traumatic stress disorder (PTSD). Fifteen veterans with combat-related PTSD and no other psychiatric diagnosis except depression were recruited to participate in a 14-week open-label study of f...
journal_title:Depression and anxiety
pub_type: 临床试验,杂志文章
doi:10.1002/da.1082
更新日期:2002-01-01 00:00:00
abstract::We assessed psychophysiological responses to imagery of traumatic events, panic attacks, and loss of vigilance (i.e., being hypnotized) in participants diagnosed with panic disorder. Participants were either currently experiencing nocturnal panic or daytime panics only. It was hypothesized that nocturnal panickers wou...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.10091
更新日期:2003-01-01 00:00:00
abstract::A key component of how depression may impact personality pathology involves an understanding of how cognition and dysfunctional attitudes may change as a result of experiencing a depressive state, and how these changes may affect reporting of personality disorder symptoms. This study examines whether dysfunctional att...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.20174
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Hoarding Disorder (HD) is currently under consideration for inclusion as a distinct disorder in DSM-5 (1). Few studies have examined comorbidity patterns in people who hoard, and the ones that have suffer from serious methodological shortcomings including drawing from populations already diagnosed with obses...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20861
更新日期:2011-10-03 00:00:00
abstract:BACKGROUND:Recent evidence shows that screen time may be an important risk factor for mental health. The aim of this study was to examine the association of computer/mobile devices (CMD) use and TV watching separately with depressive symptoms in a large representative sample of Chinese adults. METHODS:A sample of 18,9...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22932
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Complicated grief (CG) is a bereavement-specific syndrome distinct from but commonly comorbid with posttraumatic stress disorder (PTSD). While bereavement is common among military personnel (Simon et al., 2018), there is little research on the impact of CG comorbidity on PTSD treatment outcomes. METHODS:To ...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.22911
更新日期:2020-01-01 00:00:00
abstract::Research has shown that obsessive compulsive disorder (OCD) is related to structural and functional abnormalities in the brain, and several authors have organized these findings into theories of OCD neuropsychiatric dysfunction. In this paper, these theories were used to develop a neural network model of OCD. OCD symp...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/(sici)1520-6394(1998)8:3<91::aid-da1>3.0.c
更新日期:1998-01-01 00:00:00
abstract::Age at onset is an important dimension in the classification of mood disorders. Recent findings on early-onset (EO) versus late-onset (LO) unipolar chronic depressions support this subtyping. The aim of the present study was to determine clinical differences between EO and LO bipolar II chronic depression and to suppo...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/1520-6394(2001)13:1<45::aid-da7>3.0.co;2-4
更新日期:2001-01-01 00:00:00
abstract::It is well known that insomnia is more frequent in women than in men throughout all age groups. In this respect insomnia resembles other psychiatric disorders that occur more frequently in women such as anxiety and depressive disorders. Since insomnia is frequently a symptom of anxiety and depression, it remains an op...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.10101
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:We examined the prevalence and predictors of past-year antidepressant use in a nationally representative sample of Asian Americans and non-Latino Whites. METHODS:Analyses of 12-month antidepressant medication use were based on data from the Collaborative Psychiatric Epidemiology Surveys that surveyed Asian ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20636
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Transdiagnostic cognitive-behavioral treatments for anxiety disorders have been gaining increased attention and empirical study in recent years. Despite this, research on transdiagnostic anxiety treatments has, to date, relied on open trials, or comparisons to waitlist conditions, published benchmarks, or re...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.21974
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:We used a dot-probe paradigm to examine attention bias toward threat (i.e., angry) and happy face stimuli in severe mood dysregulation (SMD) versus healthy comparison (HC) youth. The tendency to allocate attention to threat is well established in anxiety and other disorders of negative affect. SMD is charact...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22145
更新日期:2014-07-01 00:00:00
abstract::Obsessive-compulsive disorder (OCD) is a clinically heterogeneous disorder; nonetheless, most of the previous neuropsychological studies for assessing the involvement of memory dysfunction grouped together patients with different symptoms, thereby potentially accounting for the inconsistencies of results. The goals of...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20377
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Many patients with major depressive disorder (MDD) have been found to have psychotic symptoms. However, few studies have reported the prevalence of comorbid psychotic symptoms in first-episode drug naïve (FEDN) MDD patients. This study was to investigate the prevalence of psychotic symptoms and related risk ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.23026
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Recent studies suggest that mindfulness may be an effective component for posttraumatic stress disorder (PTSD) treatment. Mindfulness involves practice in volitional shifting of attention from "mind wandering" to present-moment attention to sensations, and cultivating acceptance. We examined potential neural...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22481
更新日期:2016-04-01 00:00:00
abstract::Social support is proposed to attenuate behavioral consequences of exposure to uncontrollable stressors. To test this possibility, we compared the effects of two post-stress housing conditions, in pairs or in groups of 10-12 animals per cage, on the behavior of rats tested in the elevated plus-maze (EPM) 24 hr after s...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.10124
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Panic disorder (PD) is highly comorbid with major depressive disorder (MDD) with potential impact on patient-reported outcomes of quality of life (QOL), functioning, and depressive symptom severity. METHODS:Using data from the sequenced treatment alternatives to relieve depression (STAR*D) trial, we compare...
journal_title:Depression and anxiety
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/da.22152
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Repetitive transcranial magnetic stimulation (rTMS) has shown safety and efficacy for treatment-resistant depression, but requires daily treatment for 4-6 weeks. Accelerated TMS, with all treatments delivered over a few days, would have significant advantages in terms of access and patient acceptance. METHO...
journal_title:Depression and anxiety
pub_type: 临床试验,杂志文章
doi:10.1002/da.20731
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVES:To explore the anxiolytic effects of a 4-month randomized, placebo-controlled trial of exercise and antidepressant medication in patients with major depressive disorder (MDD), and to examine the potential modifying effects of anxiety in treating depressive symptoms. MATERIALS AND METHODS:In this secondary a...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.23088
更新日期:2020-08-12 00:00:00
abstract::The growing recognition and occurrence of traumatic exposure in the general population has given increased salience to the need to understand the concept of resilience. More than just the "flip side" of a risk factor, the notion of resilience encompasses psychological and biological characteristics, intrinsic to an in...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.20175
更新日期:2007-01-01 00:00:00
abstract::In this analysis we examined studies of tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) to compare efficacy and drop-out rates. Frequency of reported side effects was also studied. Using Medline, we located 36 clinical trials of TCAs and SSRIs in a double-blind comparison. We perfo...
journal_title:Depression and anxiety
pub_type: 杂志文章,meta分析
doi:10.1002/(sici)1520-6394(1997)6:1<10::aid-da2>3.0.c
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Previous work has shown that inhibition of fear is impaired in posttraumatic stress disorder (PTSD) resulting from both civilian and combat trauma. The purpose of the present study was to investigate the inhibition of learned fear in traumatized individuals diagnosed with either acute stress disorder (ASD) o...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.21991
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:In this randomized controlled trial, cognitive-behavioral group therapy (CBGT) for social anxiety disorder (SAD) was compared to group psychotherapy (GPT), a credible, structurally equivalent control condition that included only nonspecific factors of group treatment (such as group dynamics). METHODS:Partici...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.20877
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Although trauma-focused cognitive behavioral therapy (TF-CBT) is the frontline treatment for posttraumatic stress disorder (PTSD), at least one-third of patients are treatment nonresponders. This study aimed to identify neural markers of treatment response, specifically the prediction of remission of specifi...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.23061
更新日期:2020-10-01 00:00:00
abstract::We successfully treated a 46-year-old narcoleptic woman suffering from atypical depression with bupropion hydrochloride. Diagnostic evaluation revealed a Beck Depression Inventory (BDI) score of 24, a short nocturnal REM-sleep latency, subjective and objective sleepiness (mean sleep latency (MSL) = 1.8 minutes), and t...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Synchronized transcranial magnetic stimulation (sTMS) is a new modality to reduce symptoms of major depressive disorder (MDD). sTMS uses rotating neodymium magnets to deliver low-field stimulation matched to the individual alpha frequency (IAF). A previous multisite study showed that sTMS significantly reduc...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22862
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Self-esteem is a major concern in mood disorders. Low self-esteem is a symptom of depressive disorders and is considered by some to be a predictor for relapse, whereas high self-esteem seems to buffer against depression. Recently, Competitive Memory Training (COMET) has shown to be effective for the enhancem...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.20921
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Maintenance of gains with cognitive-behavioral treatment for trichotillomania (TTM) has historically been problematic. METHODS:We conducted follow-up assessments 3 and 6 months after completion of a 3-month maintenance phase on 10 individuals with DSM-IV-TR TTM who participated in an open trial of a dialect...
journal_title:Depression and anxiety
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/da.20778
更新日期:2011-04-01 00:00:00