Abstract:
BACKGROUND:Axis I comorbidity complicates diagnosing axis II personality disorders (PDs). PDs might influence Axis I outcome. No research has examined psychotherapy effects on PDs of treating Axis I comorbidity. Secondary analysis of a randomized controlled trial examined PD diagnostic stability after brief psychotherapy of chronic posttraumatic stress disorder (PTSD). METHODS:Patients with chronic PTSD were randomly assigned to 14 weeks of prolonged exposure, interpersonal psychotherapy, or relaxation therapy. Assessments included the Structured Clinical Interview for DSM-IV, Patient Version (SCID-P) and Structured Clinical Interview for DSM-IV Axis II Disorders (SCID-II) at baseline, week 14, and for treatment responders (≥30% clinician-administered PTSD scale improvement, defined a priori) at week 26 follow-up. We hypothesized patients whose PTSD improved would retain fewer baseline PD diagnoses posttreatment, particularly with personality traits PTSD mimics, e.g. paranoid and avoidant. RESULTS:Forty-seven (47%) of 99 SCID-II patients evaluated at baseline received a SCID-II diagnosis: paranoid (28%), obsessive-compulsive (27%), and avoidant (23%) PDs were most prevalent. Among 78 patients who repeated SCID-II evaluations posttreatment, 45% (N = 35) had baseline PD diagnoses, of which 43% (N = 15/35) lost at week 14. Three (7%) patients without baseline PDs acquired diagnoses at week 14; 10 others shifted diagnoses. Treatment modality and PTSD response were unrelated to PD improvement. Of treatment responders reevaluated at follow-up (N = 44), 56% with any baseline Axis II diagnosis had none at week 26. CONCLUSION:This first evaluation of Axis I psychotherapy effects on personality disorder stability found that acutely treating a chronic state decreased apparent trait-across most PDs observed. These exploratory findings suggest personality diagnoses may have limited prognostic meaning in treating chronic PTSD.
journal_name
Depress Anxietyjournal_title
Depression and anxietyauthors
Markowitz JC,Petkova E,Biyanova T,Ding K,Suh EJ,Neria Ydoi
10.1002/da.22436subject
Has Abstractpub_date
2015-12-01 00:00:00pages
919-26issue
12eissn
1091-4269issn
1520-6394journal_volume
32pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Many individuals with obsessive-compulsive disorder (OCD) do not receive professional treatment due to various idiosyncratic barriers. Internet-based cognitive-behavioral therapy (iCBT) is increasingly used to narrow treatment gaps, but the efficacy of such interventions without guidance of therapists has no...
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abstract::The psychometric properties of the Social Phobia Anxiety Inventory (SPAI) were assessed in a sample of participants who either had a primary diagnosis of social phobia or were normal volunteers. Positive evidence was obtained on the SPAI's concurrent and predictive convergent validity: it was significantly correlated ...
journal_title:Depression and anxiety
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abstract::Acute grief is emotionally intense, cognitively preoccupying, and disruptive, but grief is not an illness; major depression and anxiety disorders are. Grief and mourning have a purpose. They provide an intense, focused opportunity to reregulate emotion and to engage in a learning process that is aimed at reconfiguring...
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20231
更新日期:2007-01-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22145
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更新日期:2010-03-01 00:00:00
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更新日期:2010-03-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22710
更新日期:2018-04-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22083
更新日期:2013-05-01 00:00:00
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journal_title:Depression and anxiety
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doi:10.1002/da.23101
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journal_title:Depression and anxiety
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journal_title:Depression and anxiety
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,随机对照试验
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更新日期:2012-10-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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更新日期:2013-02-01 00:00:00
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journal_title:Depression and anxiety
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1998-01-01 00:00:00
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