Abstract:
BACKGROUND:Whether psychological resilience correlates with neurocognitive performance is largely unknown. Therefore, we assessed association between neurocognitive performance and resilience in individuals with a history of childhood abuse or trauma exposure. METHODS:In this cross-sectional study of 226 highly traumatized civilians, we assessed neurocognitive performance, history of childhood abuse and other trauma exposure, and current depressive and PTSD symptoms. Resilience was defined as having > or =1 trauma and no current depressive or PTSD symptoms; non-resilience as having > or =1 trauma and current moderate/severe depressive or PTSD symptoms. RESULTS:The non-resilient group had a higher percentage of unemployment (P=.006) and previous suicide attempts (P<.0001) than the resilient group. Both groups had comparable education and performance on verbal reasoning, nonverbal reasoning, and verbal memory. However, the resilient group performed better on nonverbal memory (P=.016) with an effect size of .35. Additionally, more severe childhood abuse or other trauma exposure was significantly associated with non-resilience. Better nonverbal memory was significantly associated with resilience even after adjusting for severity of childhood abuse, other trauma exposure, sex, and race using multiple logistic regression (adjusted OR=1.2; P=.017). CONCLUSIONS:We examined resilience as absence of psychopathology despite trauma exposure in a highly traumatized, low socioeconomic, urban population. Resilience was significantly associated with better nonverbal memory, a measure of ability to code, store, and visually recognize concrete and abstract pictorial stimuli. Nonverbal memory may be a proxy for emotional learning, which is often dysregulated in stress-related psychopathology, and may contribute to our understanding of resilience.
journal_name
Depress Anxietyjournal_title
Depression and anxietyauthors
Wingo AP,Fani N,Bradley B,Ressler KJdoi
10.1002/da.20675subject
Has Abstractpub_date
2010-08-01 00:00:00pages
768-74issue
8eissn
1091-4269issn
1520-6394journal_volume
27pub_type
杂志文章abstract:OBJECTIVE:To examine (1) clinically relevant anxiety with comorbid depression in an older population, and the presentation of subthreshold symptoms; (2) to assess anxiety and levels of comorbid depression associated with migration, religion, loneliness and long-term illness. METHODS:Analysis of Wave 1 of The Irish Lon...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22893
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Irritability is prevalent and impairing in pediatric bipolar disorder (BD) but has been minimally studied using neuroimaging techniques. We used magnetoencephalography (MEG) to study theta band oscillations in the anterior cingulate cortex (ACC) during frustration in BD youth. ACC theta power is associated w...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20649
更新日期:2010-03-01 00:00:00
abstract::We successfully treated a 46-year-old narcoleptic woman suffering from atypical depression with bupropion hydrochloride. Diagnostic evaluation revealed a Beck Depression Inventory (BDI) score of 24, a short nocturnal REM-sleep latency, subjective and objective sleepiness (mean sleep latency (MSL) = 1.8 minutes), and t...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::The increased risk of physical health problems in adult depressed patients has been shown in numerous studies. A recent study of the offspring of depressed parents found similar associations. The purpose of this study is to examine the strength and specificity of the association between depression and physical health ...
journal_title:Depression and anxiety
pub_type: 临床试验,杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::The growing recognition and occurrence of traumatic exposure in the general population has given increased salience to the need to understand the concept of resilience. More than just the "flip side" of a risk factor, the notion of resilience encompasses psychological and biological characteristics, intrinsic to an in...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.20175
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Chronotype is an individual's preferred timing of sleep and activity, and is often referred to as a later chronotype (or evening-type) or an earlier chronotype (or morning-type). Having an evening chronotype is associated with more severe depressive and anxiety symptoms. Based on these findings it is has bee...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22995
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Although there has been abundant research on chronic low-grade inflammation as a potential mechanism underlying the link between mood disorders and cardiovascular risk, less is known about the role of inflammatory factors and anxiety disorders. The aim of this paper is to evaluate the bi-directional associat...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22710
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Oligodendrocyte transcription factor 2 (OLIG2) is primarily concentrated in the brain and spinal cord ventricular zone, where this protein stimulates oligodendrocytes and specific neurons, determines motor neuron and oligodendrocyte differentiation, and sustains replication in early development. Recent studi...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22394
更新日期:2015-10-01 00:00:00
abstract::Thus, there appears to be a large variety of approaches to refractory bipolar depression. In contrast to several decades ago, wherein augmentation of lithium with antidepressants and neuroleptics was essentially the only treatment mode available, a panoply of treatment options now exist. However, their relative effica...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Vilazodone, a selective serotonin reuptake inhibitor and 5-HT1A receptor partial agonist, is approved for treating major depressive disorder in adults. This study (NCT01629966 ClinicalTrials.gov) evaluated the efficacy and safety of vilazodone in adults with generalized anxiety disorder (GAD). METHODS:A mul...
journal_title:Depression and anxiety
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/da.22365
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Adolescent depression may increase risk for poor mental health outcomes in adulthood. The objective of this study was to systematically review the literature on the association between adolescent depression and adult anxiety and depressive disorders as well as suicidality. METHODS:EMBASE, MEDLINE, and PSYCi...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.22777
更新日期:2018-08-01 00:00:00
abstract::This multicenter study estimated the prevalence of major depressive disorder (MDD) among emergency department patients in Latin America. To identify patients with MDD, we used a combination of DSM IV- criteria interview and a questionnaire screen including the center for Epidemiological Studies Depression Scale. We an...
journal_title:Depression and anxiety
pub_type: 杂志文章,多中心研究
doi:10.1002/da.20380
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Individuals with depression may not seek treatment for their symptoms due to several types of barriers to treatment. In support of the growing research on mental health care access and the role of social media, this study aimed to increase knowledge of these barriers among social media users. METHODS:Partic...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22990
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Television (TV) viewing and computer use have been associated with higher risk of depression, but studies specifically assessing the impact of these and other types of sedentary behaviors (SBs) on the mental health of older adults are scarce and their results are inconclusive. Similarly, the association betw...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22804
更新日期:2018-09-01 00:00:00
abstract::This study aimed to assess the effects of anisomycin, a protein synthesis inhibitor, on behavioral responses, brain-derived neurotrophic factor (BDNF) and TrkB mRNA levels, and circulating corticosterone in rats-when administered before or after initial exposure to a predator scent stress stimulus. Magnitude of change...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20366
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Recent research suggests that posttraumatic stress disorder (PTSD) is associated with altered amygdala and hippocampal resting-state functional connectivity (rsFC). However, less research has examined whether Prolonged Exposure (PE), a first line exposure-based treatment for PTSD, has the potential to alter ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22816
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Previous work has shown that inhibition of fear is impaired in posttraumatic stress disorder (PTSD) resulting from both civilian and combat trauma. The purpose of the present study was to investigate the inhibition of learned fear in traumatized individuals diagnosed with either acute stress disorder (ASD) o...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.21991
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:In previous reports from the Rhode Island Methods to Improve Diagnostic Assessment and Services project, we developed a briefer definition of major depressive disorder (MDD), and found high levels of agreement between the simplified and DSM-IV definitions of MDD. The goal of the present study was to examine ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20710
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Complicated grief (CG) is a bereavement-specific syndrome distinct from but commonly comorbid with posttraumatic stress disorder (PTSD). While bereavement is common among military personnel (Simon et al., 2018), there is little research on the impact of CG comorbidity on PTSD treatment outcomes. METHODS:To ...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.22911
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Investigations of gene-environment interaction (GxE) in depression have implicated a polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) as a moderator of the stress-depression relationship. However, recent evidence for 5-HTTLPR GxE in depression has been inconsistent. This study...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20715
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Many individuals with obsessive-compulsive disorder (OCD) do not receive professional treatment due to various idiosyncratic barriers. Internet-based cognitive-behavioral therapy (iCBT) is increasingly used to narrow treatment gaps, but the efficacy of such interventions without guidance of therapists has no...
journal_title:Depression and anxiety
pub_type: 杂志文章,随机对照试验
doi:10.1002/da.23105
更新日期:2020-12-01 00:00:00
abstract::Memory function was studied in combat veterans with posttraumatic stress disorder (PTSD), combat veterans without PTSD, and noncombat veterans. The Vocabulary and Digit Span subtests of the WAIS and Logical Memory (LMS) and Verbal Paired Associates (VPAS) subtests of the Wechsler Memory Scale III were administered. Co...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.20291
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:There has been little research on the generalizability of clinical trials for generalized anxiety disorder (GAD). The present study examines the generalizability of pharmacological and psychotherapy clinical trials' results of individuals with DSM-IV GAD to a large community sample. METHODS:Data were drawn ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.21937
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Although evidence-based psychotherapies (EBPs) for posttraumatic stress disorder (PTSD) were implemented starting in 2005 in the veterans health administration (VHA), the largest national healthcare system in the U.S., the rate of initiation (uptake) and prevalence of these treatments in each calendar year h...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22983
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Diagnostic criteria for DSM-5 posttraumatic stress disorder (PTSD) are in many ways similar to DSM-IV criteria, raising the possibility that it might be possible to closely approximate DSM-5 diagnoses using DSM-IV symptoms. If so, the resulting transformation rules could be used to pool research data based o...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22364
更新日期:2015-07-01 00:00:00
abstract::Cognitive therapy of depression, based on the cognitive theory of depression, is an established treatment for major depressive disorder. Although few clinicians expect acute treatment of depression with antidepressant medication to prevent long-term relapse of the illness, some practitioners of cognitive therapy repor...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/da.20022
更新日期:2004-01-01 00:00:00
abstract::Depressive symptoms, due either major depression or clinically significant, subsyndromal depression, occur commonly in the course of Alzheimer's disease. For a variety of clinical and methodological reasons, this remains an area that begs for new investigation. At the very least, these depressive symptoms should be vi...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Processes of phasic fear responses to threatening stimuli are thought to be distinct from sustained, anticipatory anxiety toward an unpredicted, potential threat. There is evidence for dissociable neural correlates of phasic fear and sustained anxiety. Whereas increased amygdala activity has been associated ...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22382
更新日期:2015-09-01 00:00:00
abstract::Pediatric psychopharmacology is hindered by the relative lack of controlled, empirical clinical trials [Shatzberg and Nemeroff, 1998: Washington, D.C.: The American Psychiatric Press, Inc. p 301-306]. Psychiatric disorders in children and adolescents carry considerable morbidity, impede development, and carry a signif...
journal_title:Depression and anxiety
pub_type: 杂志文章,评审
doi:10.1002/1520-6394(2000)12:1+<85::AID-DA12>3.0.CO;2
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Although a large body of empirical research has examined negative psychological outcomes in older veterans, relatively little is known about the prevalence and determinants of psychological resilience in this population. METHODS:A nationally representative sample of 2,025 U.S. veterans aged 60 and older (me...
journal_title:Depression and anxiety
pub_type: 杂志文章
doi:10.1002/da.22083
更新日期:2013-05-01 00:00:00